- 2018
- Published
Spatial QRS-T angle variants for prediction of all-cause mortality
Kück, K., Isaksen, Jonas L., Graff, C., Skaaby, T., Linneberg, Allan René, Hansen, Torben & Kanters, Jørgen K., 2018, In: Journal of Electrocardiology. 51, 5, p. 768-775 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific synbiotics in early life protect against diet-induced obesity in adult mice
Mischke, M., Arora, Tulika, Tims, S., Engels, E., Sommer, N., van Limpt, K., Baars, A., Oozeer, R., Oosting, A., Bäckhed, F. & Knol, J., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1408-1418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sperm epigenetics and influence of environmental factors
Donkin, I. & Barrès, Romain, 2018, In: Molecular Metabolism. 14, p. 1-11 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Squeezing Flux Out of Fat
Gonzalez-Franquesa, A. & Patti, M., 2018, In: Trends in Endocrinology and Metabolism. 29, 4, p. 201-202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome
Jensen, Theis Zetner Trolle, Niemann, Jonas, Iversen, K. H., Fotaki, Anna Katerina, Gopalakrishan, S., Sinding, Mikkel Holger Strander, Ellegaard, M. R., Allentoft, Morten Erik, Lanigan, Liam Thomas, Taurozzi, Alberto John, Nielsen, Sofie Holtsmark, Dee, M. W., Mortensen, M. N., Christensen, M. C., Sørensen, S. A., Collins, Matthew James, Gilbert, M Thomas P, Sikora, Martin, Rasmussen, Simon & Schroeder, Hannes, 2018, bioRxiv, 32 p.Research output: Working paper › Preprint › Research
- Published
Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation
Milanos, S., Kuenzel, K., Gilbert, D. F., Janzen, D., Sasi, M., Buettner, A., Frimurer, Thomas Michael & Villmann, C., 2018, In: Biological Chemistry. 399, 6, p. 549-563 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Succesfuld behandling af KCNJ11-neonatal diabetes uden insulin
Gade-Rasmussen, B., Madsbad, Sten, Svane, M. S., Martinussen, C. & Hansen, Torben, 2018, In: Ugeskrift for Laeger. 180, 46, 2 p., V08180547.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Systems signatures reveal unique remission-path of Type 2 diabetes following Roux-en-Y gastric bypass surgery
Li, Q-R., Wang, Z-M., Albrechtsen, N. J. W., Wang, D-D., Su, Z-D., Gao, X-F., Wu, Q-Q., Zhang, H-P., Zhu, L., Li, R-X., Jacobsen, S., Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Petersen, J. S., Madsbad, S., Clausen, T. R., Diderichsen, B., Chen, L-N., Holst, J. J. & 2 others, , 2018, In: EBioMedicine. 28, p. 234-240 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
T cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors
Daniel, S., Nylander, V., Ingerslev, L. R., Zhong, L., Fabre, O., Clifford, B., Johnston, K., Cohn, R. J., Barrès, Romain & Simar, D., 2018, In: Clinical Epigenetics. 10, p. 1-13 138.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Combination of Fosfomycin, Metronidazole, and Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is Stable in vitro and Has Maintained Antibacterial Activity
Fonnes, S., Holzknecht, Barbara Juliane, Gasbjerg, Lærke Smidt, Weisser, J. J., Hallberg, H. W., Arpi, M. & Rosenberg, Jacob, 2018, In: Drug Research. 68, 6, p. 349-354Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals
Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Møller, H., Gillum, M., Gronbaek, H., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes. 67, Supplement 1, 2415-PUB.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The HETE Is on FFAR1 and Pancreatic Islet Cells
Trauelsen, Mette, Lückmann, Michael, Frimurer, Thomas Michael & Schwartz, Thue W., 2018, In: Cell Metabolism. 27, 2, p. 273-275 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease
Makki, K., Deehan, E. C., Walter, J. & Backhed, F., 2018, In: Cell Host & Microbe. 23, 6, p. 705-715Research output: Contribution to journal › Review › Research › peer-review
- Published
The Intestinotrophic Effects of Glucagon-Like Peptide-2 in Relation to Intestinal Neoplasia
Orhan, Adile, Gögenur, Ismail & Kissow, Hannelouise, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2827-2837Research output: Contribution to journal › Review › Research › peer-review
- Published
The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes
Hædersdal, S., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Mayo Clinic Proceedings. 93, 2, p. 217-239Research output: Contribution to journal › Review › Research › peer-review
- Published
The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial
Samkani, A., fbg982, fbg982, Anholm, C., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S., Boston, R., Krarup, T. & Haugaard, Steen Bendix, 2018, In: Lipids in Health and Disease. 17, 9 p., 295.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The complement system is differently regulated in white and brown adipocytes
Justesen, L., Bayarri-Olmos, R., Schéele, Camilla Charlotte Nielsen & Garred, Peter, 2018, In: Molecular Immunology. 102, p. 170 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.
Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults
Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects
Schmedes, M. S., Bendtsen, L. Q., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael, Astrup, A., Young, J. F., Sundekilde, U. K. & Bertram, H. C., 2018, In: Journal of the Science of Food and Agriculture. 98, 15, p. 5598-5605 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of diaries written by relatives for intensive care patients on posttraumatic stress (DRIP study): protocol for a randomized controlled trial and mixed methods study
Nielsen, A. H., Angel, S., Egerod, Ingrid Eugenie & Hansen, Torben, 2018, In: BMC Nursing. 17, p. 1-10 10 p., 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention
Hansen, T. H., Thomassen, M. T., Madsen, M. L., Kern, T., Bak, Emilie Glad, Kashani, A., Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 2018, In: Scientific Reports. 8, 12 p., 16626.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of impaired glucose metabolism on weight loss in multidisciplinary childhood obesity treatment
Kloppenborg, J. T., Gamborg, Michael Orland, Fonvig, Cilius Esmann, Nielsen, T. R. H., Pedersen, Oluf Borbye, Johannesen, Jesper, Hansen, Torben & Holm, Jens-Christian, 2018, In: Pediatric Diabetes. 19, 3, p. 366-374 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial
Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants
Sigalet, D. L., Lam, V., Brindle, M., Boctor, D., Wallace, L., de Heuval, E., Hartmann, Bolette & Holst, Jens Juul, 2018, In: Journal of Pediatric Surgery. 53, 5, p. 898-904Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon
Christiansen, Charlotte Bayer, Gabe, M. B. N., Svendsen, B., Dragsted, Lars Ove, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the incretins in the postprandial bone remodelling
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
Kleinert, Maximilian, Kotzbeck, P., Altendorfer-Kroath, T., Birngruber, T., Tschöp, M. H. & Clemmensen, Christoffer, 2018, In: Molecular Metabolism. 13, p. 77-82 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Translating biased signaling in the ghrelin receptor system into differential in vivo functions
Mende, F., Johnsen, Cecilie Hundahl, Plouffe, B., Skov, Louise Julie, Sivertsen, B., Madsen, A. N., Lückmann, Michael, Diep, T. A., Offermanns, S., Frimurer, Thomas Michael, Bouvier, M. & Holst, Birgitte, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10255-E10264 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment with GLP-1 Receptor Agonists
Madsbad, Sten & Holst, Jens Juul, 2018, Diabetes: Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 45 p. (Endocrinology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Universal infant health interventions and young adult outcomes
Wüst, Miriam, Mortensen, Erik Lykke, Osler, Merete & Sørensen, Thorkild I.A., 2018, In: Health Economics. 27, 8, p. 1319-1324 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Volume of ropivacaine 0.2% and common peroneal nerve block duration: a randomised, double-blind cohort trial in healthy volunteers
Christiansen, Charlotte Bayer, Madsen, M. H., Rothe, C., Andreasen, A. M., Lundstrøm, L. H. & Lange, Kai, 2018, In: Anaesthesia. 73, 11, p. 1361-1367 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression
Ren, S., Wei, G-H., Liu, D., Wang, L., Hou, Y., Zhu, S., Peng, L., Zhang, Q., Cheng, Y., Su, H., Zhou, X., Zhang, J., Li, F., Zheng, H., Zhao, Z., Yin, C., He, Z., Gao, X., Zhau, H. E., Chu, C-Y. & 42 others, , 2018, In: European Urology. 73, 3, p. 322-339 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Why looking at things matter: An argument from the aesthethic philosophy of Alexander Gottlieb Baumgarten
Bencard, Adam, 2018, In: Museums Worlds: Advances in Research. 6, 1, p. 48-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, , 19 Dec 2017, In: Scientific Data. 4, p. 1-20 20 p., 170179.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the relationship between glucose absorption and glucose‐stimulated secretion of GLP‐1, neurotensin, and PYY from different intestinal segments in the rat
Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Saltiel, M. Y., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 3 Dec 2017, In: Physiological Reports. 5, 23, 13 p., e13507.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial
Jin, C., Gibani, M. M., Moore, M., Juel, H. B., Jones, E., Meiring, J., Harris, V., Gardner, J., Nebykova, A., Kerridge, S. A., Hill, J., Thomaides-Brears, H., Blohmke, C. J., Yu, L. M., Angus, B. & Pollard, A. J., 2 Dec 2017, In: The Lancet. 390, 10111, p. 2472-2480 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery, characterization, and clinical development of the glucagon-like peptides
Drucker, D. J., Habener, J. F. & Holst, Jens Juul, 1 Dec 2017, In: The Journal of Clinical Investigation. 127, 12, p. 4217-4227 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Roles of increased glycemic variability, GLP-1 and glucagon in hypoglycaemia after Roux-en-Y gastric bypass
Tharakan, G., Behary, P., Albrechtsen, Nicolai Jacob Wewer, Chahal, H., Kenkre, J., Miras, A. D., Ahmed, A. R., Holst, Jens Juul, Bloom, S. R. & Tan, T. M. M., 1 Dec 2017, In: European Journal of Endocrinology. 177, p. 455-464 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, , Dec 2017, In: Diabetes. 66, p. 2019-2032 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study
Kjær, L. K., Cejvanovic, V., Henriksen, T., Petersen, K. M., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, Dec 2017, In: Diabetes Care. 40, 12, p. 1771-1778 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index and height in relation to site-specific risks of colorectal cancers in adult life
Jensen, B. W., Gamborg, M., Gögenur, Ismail, Renehan, A. G., Sørensen, Thorkild I.A. & Baker, J. L., Dec 2017, In: European Journal of Epidemiology. 32, 12, p. 1097-1106Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 acutely affects renal blood flow and urinary flow rate in spontaneously hypertensive rats despite significantly reduced renal expression of GLP-1 receptors
Ronn, J., Jensen, E. P., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Sorensen, Charlotte Mehlin, Dec 2017, In: Physiological Reports. 5, 23, 14 p., e13503.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired beta cell sensitivity to incretins in type 2 diabetes is insufficiently compensated by higher incretin response
Tura, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina & Mari, A., Dec 2017, In: Nutrition, Metabolism and Cardiovascular Diseases. 27, 12, p. 1123-1129 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice
Camporez, J. P., Wang, Y., Faarkrog, K., Chukijrungroat, N., Petersen, K. F. & Shulman, G. I., Dec 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 52, p. E11285-E11292 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient re-routing and altered gut-islet cell crosstalk may explain early relief of severe postprandial hypoglycaemia after reversal of Roux-en-Y gastric bypass
Svane, M. S., Toft-Nielsen, M. B., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., Dec 2017, In: Diabetic Medicine Online. 34, 12, p. 1783-1787Research output: Contribution to journal › Letter › Research › peer-review
- Published
Parent perspectives on biomarkers for OCD: Talking of difficult presents, desired pasts, and imagined futures
Whiteley, Louise, Borgelt, E. L., Stewart, S. E. & Illes, J., Dec 2017, In: BioSocieties. 12, 4, p. 471–493 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Trauelsen, Mette, Ulven, Elisabeth Rexen, Hjorth, Siv Annegrethe, Brvar, M., Monaco, C., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2017, In: Molecular Metabolism. 6, 12, p. 1585-1596 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subjective evaluation of psychosocial well-being in children and youths with overweight or obesity: the impact of multidisciplinary obesity treatment
Fonvig, Cilius Esmann, Hamann, S. A., Nielsen, T. R. H., Johansen, M. Ø., Grønbæk, H. N., Mollerup, P. M. & Holm, Jens-Christian, Dec 2017, In: Quality of Life Research. 26, 12, p. 3279-3288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unchanged mitochondrial phenotype, but accumulation of lipids in the myometrium in obese pregnant women
Gam, C. M. B. F., Larsen, L. H., Mortensen, Ole Hartvig, pjx571, pjx571, Poulsen, Steen Seier, Qvortrup, Klaus, Mathiesen, Elisabeth, Damm, Peter & Quistorff, B., Dec 2017, In: Journal of Physiology. 595, 23, p. 7109-7122 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environmental spread of microbes impacts the development of metabolic phenotypes in mice transplanted with microbial communities from humans
Zhang, L., Bahl, M. I., Roager, Henrik Munch, Fonvig, C. E., Hellgren, L. I., Frandsen, H. L., Pedersen, Oluf Borbye, Holm, Jens-Christian, Hansen, Torben & Licht, T. R., 18 Nov 2017, In: The ISME Journal. 11, p. 676-690 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Fixation Redefines Quiescence and Early Activation of Skeletal Muscle Stem Cells
Machado, L., Esteves de Lima, J., Fabre, O., Proux, C., Legendre, R., Szegedi, A., Varet, H., Ingerslev, L. R., Barrès, Romain, Relaix, F. & Mourikis, P., 14 Nov 2017, In: Cell Reports. 21, 7, p. 1982-1993 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans
Laker, R. C., Garde, C., Camera, D. M., Smiles, W. J., Zierath, Juleen R, Hawley, J. A. & Barrès, Romain, 9 Nov 2017, In: Scientific Reports. 7, 1, 12 p., 15134.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic determinants of circulating GIP and GLP-1 concentrations
Almgren, P., Lindqvist, A., Krus, U., Hakaste, L., Ottosson-Laakso, E., Asplund, O., Sonestedt, E., Prasad, R. B., Laurila, E., Orho-Melander, M., Melander, O., Tuomi, T., Holst, Jens Juul, Nilsson, P. M., Wierup, N., Groop, L. & Ahlqvist, E., 2 Nov 2017, In: JCI insight. 2, 21, 13 p., e93306.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of childhood body mass index and change in body mass index with first adult ischemic stroke
Gjærde, L. K., Gamborg, M., Ängquist, Lars, Truelsen, T. C., Sørensen, Thorkild I.A. & Baker, J. L., 1 Nov 2017, In: JAMA Neurology. 74, 11, p. 1312-1318 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes
Wendt, S. L., Ranjan, A., Møller, J. K., Schmidt, S., Knudsen, C. B., Holst, Jens Juul, Madsbad, Sten, Madsen, H., Nørgaard, Kirsten & Jørgensen, J. B., 1 Nov 2017, In: Journal of Diabetes Science and Technology. 11, 6, p. 1101-1111 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence Suggesting Absence of Mitochondrial DNA Methylation
Mechta, Mie, Ingerslev, L. R., Fabre, O., Picard, M. & Barrès, Romain, 1 Nov 2017, In: Frontiers in Genetics. 8, 9 p., 166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Glucagon in Catabolism and Muscle Wasting of Critical Illness and Modulation by Nutrition
Thiessen, S. E., Derde, S., Derese, I., Dufour, T., Vega, C. A., Langouche, L., Goossens, C., Peersman, N., Vermeersch, P., Vander Perre, S., Holst, Jens Juul, Wouters, P. J., Vanhorebeek, I. & Van den Berghe, G., 1 Nov 2017, In: American Journal of Respiratory and Critical Care Medicine. 196, 9, p. 1131-1143 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response
Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527Research output: Contribution to journal › Comment/debate › Research
- Published
Association between birthweight and later body mass index: an individual-based pooled analysis of 27 twin cohorts participating in the CODATwins project
Jelenkovic, A., Yokoyama, Y., Sund, R., Pietiläinen, K. H., Hur, Y-M., Willemsen, G., Bartels, M., van Beijsterveldt, T. C., Ooki, S., Saudino, K. J., Stazi, M. A., Fagnani, C., D'Ippolito, C., Nelson, T. L., Whitfield, K. E., Knafo-Noam, A., Mankuta, D., Abramson, L., Heikkilä, K., Cutler, T. L. & 46 others, , Nov 2017, In: International Journal of Epidemiology. 46, 5, p. 1488-1498 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated Postoperative Endogenous GLP-1 Levels Mediate Effects of Roux-en-Y Gastric Bypass on Neural Responsivity to Food Cues
Ten Kulve, J. S., Veltman, D. J., Gerdes, V. E. A., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M. & IJzerman, R. G., Nov 2017, In: Diabetes Care. 40, 11, p. 1522-1529 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Host-microbiota interaction induces bi-phasic inflammation and glucose intolerance in mice
Molinaro, A., Caesar, R., Holm, L. M., Tremaroli, V., Cani, P. D. & Bäckhed, F., Nov 2017, In: Molecular Metabolism. 6, 11, p. 1371-1380 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Keeping fat on time: Circadian control of adipose tissue
Ninel Hansen, S., Peics, J. & Gerhart-Hines, Zach, Nov 2017, In: Experimental Cell Research. 360, 1, p. 31-34 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Macrophage Area Content and Phenotype in Hepatic and Adipose Tissue in Patients with Obesity Undergoing Roux-en-Y Gastric Bypass
Kristensen, M. D., Lund, M. T., Hansen, M., Poulsen, Steen Seier, Ploug, Thorkil, Dela, Flemming, Helge, Jørn Wulff & Prats Gavalda, Clara, Nov 2017, In: Obesity. 25, 11, p. 1921-1931 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies
Carrasquilla, Germán D., Frumento, P., Berglund, A., Borgfeldt, C., Bottai, M., Chiavenna, C., Eliasson, M., Engstrom, G., Hallmans, G., Jansson, J., Magnusson, P. K., Nilsson, P. M., Pedersen, N. L., Wolk, A. & Leander, K., Nov 2017, In: PLoS Medicine. 14, 11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes
Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TRPV1: A Potential Therapeutic Target in Type 2 Diabetes and Comorbidities?
Gram, D. X., Holst, Jens Juul & Szallasi, A., Nov 2017, In: Trends in Molecular Medicine. 23, 11, p. 1002-1013 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
Sharp, G. C., Salas, L. A., Monnereau, C., Allard, C., Yousefi, P., Everson, T. M., Bohlin, J., Xu, Z., Huang, R-C., Reese, S. E., Xu, C-J., Baïz, N., Hoyo, C., Agha, G., Roy, R., Holloway, J. W., Ghantous, A., Merid, S. K., Bakulski, K. M., Küpers, L. K. & 65 others, , 15 Oct 2017, In: Human Molecular Genetics. 26, 20, p. 4067-4085 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-inflammatory effects of active commuting and leisure time exercise in overweight and obese women and men: A randomized controlled trial
Gram, A. S., Bladbjerg, E., Quist, Jonas Salling, Blond, Martin Bæk, Rosenkilde, M. & Stallknecht, Bente Merete, Oct 2017, In: Atherosclerosis. 265, p. 318-324 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Lundh, M., Plucinska, Kaja, Isidor, Marie Sophie, Petersen, P. S. S. & Emanuelli, Brice, Oct 2017, In: Molecular Metabolism. 6, 10, p. 1313-1320 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index and risk of adult pancreatic cancer
Nogueira, L., Stolzenberg-Solomon, R., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., Oct 2017, In: Current Opinion in Clinical Nutrition and Metabolic Care. 1, 10, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defects in α-Cell Function in Patients With Diabetes Due to Chronic Pancreatitis Compared With Patients With Type 2 Diabetes and Healthy Individuals
Mumme, L., Breuer, T. G. K., Rohrer, S., Schenker, N., Menge, B. A., Holst, Jens Juul, Nauck, M. A. & Meier, J. J., Oct 2017, In: Diabetes Care. 40, 10, p. 1314-1322 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts
Silventoinen, K., Jelenkovic, A., Latvala, A., Sund, R., Yokoyama, Y., Ullemar, V., Almqvist, C., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Kandler, C., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Rebato, E., Stazi, M. A., Fagnani, C., Brescianini, S., Hur, Y-M. & 81 others, , Oct 2017, In: Twin Research and Human Genetics. 20, 5, p. 395-405 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, , Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition
Kootte, R. S., Levin, E., Salojärvi, J., Smits, L. P., Hartstra, A. V., Udayappan, S. D., Hermes, G., Bouter, K. E., Koopen, A. M., Holst, J. J., Knop, F. K., Blaak, E. E., Zhao, J., Smidt, H., Harms, A. C., Hankemeijer, T., Bergman, J. J. G. H. M., Romijn, H. A., Schaap, F. G., Olde Damink, S. W. M. & 8 others, , Oct 2017, In: Cell Metabolism. 26, 4, p. 611-619.e6 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose
Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, Jens Juul, Ingwersen, S. H., Karlsson, M. O., Knop, Filip Krag, Vilsbøll, Tina & Kjellsson, M. C., Oct 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 4, p. 290-297 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals
Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A. E., Fava, C., Ferreira, T., Herzig, K. H., Giri, A. & 31 others, , Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5, 9 p., e001778.Research output: Contribution to journal › Journal article › Research › peer-review
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New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A-E., Fava, C., Ferreira, T., Herzig, K-H., Giri, A. & 122 others, , Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reductions in blood pressure during a community-based overweight and obesity treatment in children and adolescents with prehypertension and hypertension
Mollerup, P. M., Lausten-Thomsen, U., Fonvig, Cilius Esmann, Baker, J. L. & Holm, Jens-Christian, Oct 2017, In: Journal of Human Hypertension. 31, p. 640-646 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial
Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Oct 2017, In: Diabetes, Obesity and Metabolism. 19, 10, p. 1479-1484Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Why is it so difficult to measure glucagon-like peptide-1 in a mouse?
Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete Genome Sequences of emm111 Type Streptococcus pyogenes Strain GUR, with Antitumor Activity, and Its Derivative Strain GURSA1 with an Inactivated emm Gene
Suvorova, M. A., Tsapieva, A. N., Bak, Emilie Glad, Chereshnev, V. A., Kiseleva, E. P., Suvorov, A. N. & Arumugam, Mani, 21 Sep 2017, In: Genome Announcements. 5, 38, 2 p., e00939-17.Research output: Contribution to journal › Journal article › Research
- Published
A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma
Chinnaswamy, S., Wardzynska, A., Pawelczyk, M., Makowska, J., Skaaby, T., Mercader, J. M., Ahluwalia, T. S., Grarup, N., Guindo-Martinez, M., Bisgaard, H., Torrents, D., Linneberg, Allan René, Bønnelykke, Klaus & Kowalski, M. L., 5 Sep 2017, In: Scientific Reports. 7, 1, p. 1-11 11 p., 10500.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite
Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A urinary proteome-based classifier for the early detection of decline in glomerular filtration
Pontillo, C., Jacobs, L., Staessen, J. A., Schanstra, J. P., Rossing, Peter, Heerspink, H. J. L., Siwy, J., Mullen, W., Vlahou, A., Mischak, H., Vanholder, R., Zürbig, P. & Jankowski, J., 1 Sep 2017, In: Nephrology, Dialysis, Transplantation. 32, 9, p. 1510-1516 7 p., gfw239.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assembly and analysis of 100 full MHC haplotypes from the Danish population
Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Sørensen, L. M., Petersen, B., Sibbesen, J. A., Liu, S., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R. & 39 others, , Sep 2017, In: Genome Research. 27, 9, p. 1597-1607 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-Free DNA in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis
Spindler, K. G., Boysen, A. K., Pallisgård, N., Johansen, Julia Sidenius, Tabernero, J., Sørensen, M. M., Jensen, B. V., Hansen, Torben, Sefrioui, D., Andersen, R. F., Brandslund, I. & Jakobsen, A., Sep 2017, In: Oncologist. 22, 9, p. 1049-1055 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric bypass
Arora, Tulika, Seyfried, F., Docherty, N. G., Tremaroli, V., le Roux, C. W., Perkins, R. & Bäckhed, F., Sep 2017, In: I S M E Journal. 11, 9, p. 2035-2046 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-Intensity Interval Training, Appetite, and Reward Value of Food in the Obese
Martins, C., Aschehoug, I., Ludviksen, M., Holst, Jens Juul, Finlayson, G., Wisloff, U., Morgan, L., King, N. & Kulseng, B., Sep 2017, In: Medicine and Science in Sports and Exercise. 49, 9, p. 1851-1858 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program
Hiraike, Y., Waki, H., Yu, J., Nakamura, M., Miyake, K., Nagano, G., Nakaki, R., Suzuki, K., Kobayashi, H., Yamamoto, S., Sun, W., Aoyama, T., Hirota, Y., Ohno, H., Oki, K., Yoneda, M., White, A. P., Tseng, Y-H., Cypess, A. M., Larsen, T. J. & 6 others, , Sep 2017, In: Nature Cell Biology. 19, 9, p. 1081-1092 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signaling Pathways as Potential Therapeutic Targets in Hepatocarcinogenesis
Yılmaz, Y., Güneş, A., Topel, Hande & Atabey, N., Sep 2017, In: Journal of Gastrointestinal Cancer. 48, 3, p. 225-237 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor
Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice
Ørgaard, A. & Holst, Jens Juul, Sep 2017, In: Diabetologia. 60, 9, p. 1731-1739 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
To see and then to act, that is the challenge
Sørensen, Thorkild I.A., Sep 2017, In: European Journal of Epidemiology. 32, 9, p. 737-739 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Alcohol consumption and its interaction with adiposity-associated genetic variants in relation to subsequent changes in waist circumference and body weight
Rohde, J. F., Ängquist, Lars, Larsen, S. C., Tolstrup, J. S., Husemoen, L. L. N., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Overvad, K., Halkjær, J., Tjønneland, A., Hansen, Torben, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Heitmann, Berit, 25 Aug 2017, In: Nutrition Journal. 16, 11 p., 51.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic and Intestinal Function Post Roux-en-Y Gastric Bypass Surgery for Obesity
O'Keefe, S. J. D., Rakitt, T., Ou, J., El Hajj, I. I., Blaney, E., Vipperla, K., Holst, Jens Juul & Rehlfeld, J., 3 Aug 2017, In: Clinical and Translational Gastroenterology. 8, 11 p., e112.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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