Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2022
  2. Published

    Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity

    Hayashi, Y., Shimizu, I., Yoshida, Y., Ikegami, R., Suda, M., Katsuumi, G., Fujiki, S., Ozaki, K., Abe, M., Sakimura, K., Okuda, S., Hayano, T., Nakamura, K., Walsh, K., Jespersen, N. Z., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Minamino, T., 2022, In: iScience. 25, 7, 23 p., 104547.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cold Exposure Drives Weight Gain and Adiposity following Chronic Suppression of Brown Adipose Tissue

    Aldiss, Peter Stuart Jacob, Lewis, J. E., Lupini, I., Bloor, I., Chavoshinejad, R., Boocock, D. J., Miles, A. K., Ebling, F. J. P., Budge, H. & Symonds, M. E., 2022, In: International Journal of Molecular Sciences. 23, 3, 16 p., 1869.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Colonic lactulose fermentation has no impact on glucagon-like peptide-1 and peptide-YY secretion in healthy young men

    Christiansen, Charlotte Bayer, Veedfald, Simon, Hartmann, Bolette, Gauguin, A. M., Møller, Søren, Moritz, Thomas, Madsbad, Sten & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. 77-87

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Combined micro-osmotic pump infusion and intracerebroventricular injection to study FGF1 signaling pathways in the mouse brain

    Brown, Jenny, Phan, B. A., Aalling, Nadia, Morton, G. J., Schwartz, M. W. & Scarlett, J. M., 2022, In: STAR Protocols. 3, 2, 16 p., 101329.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Coming Closer to Citizens? Frustrated Dialogue on the Danish Health Authority's Facebook Page During COVID-19

    Madvig, F., Achiam, Marianne, Adler-Nissen, Rebecca, Johansen, Nicklas & Whiteley, Louise, 2022, In: Frontiers in Communication. 7, 822471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Comparable Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Basal Fuel Metabolism and Insulin Sensitivity in Individuals with Obesity and Type 2 Diabetes

    Brodersen, K., Nielsen, M. F., Richelsen, B., Lauritzen, E. S., Pahle, E., Abrahamsen, J., Hartmann, Bolette, Holst, Jens Juul & Møller, N., 2022, In: Journal of Diabetes Research. 2022, 9 p., 5476454.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice

    Small, Lewin Barkla, Ehrlich, Amy M, Iversen, Jo Frøkjær, Ashcroft, Stephen Paul, Trošt, K., Moritz, Thomas, Hartmann, Bolette, Holst, Jens Juul, Treebak, Jonas Thue, Zierath, Juleen R & Barrès, Romain, 2022, In: Molecular Metabolism. 57, 8 p., 101440.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Comparative analysis of sperm DNA methylation supports evolutionary acquired epigenetic plasticity for organ speciation

    Moharrek, Farideh, Ingerslev, L. R., Altıntaş, Ali, Lundell, L., Hansen, Ann Normann, Small, Lewin Barkla, Workman, C. T. & Barrès, Romain, 2022, In: Epigenomics. 14, 21, p. 1305-1324 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Context dependency of nucleotide probabilities and variants in human DNA

    Liang, Yuhu, Grønbæk, Christian, Fariselli, P. & Krogh, Anders, 2022, In: BMC Genomics. 23, 1, 15 p., 87.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Context dependent prediction in DNA sequence using neural networks

    Grønbæk, Christian, Liang, Yuhu, Elliott, Desmond & Krogh, Anders, 2022, In: PeerJ. 10, 22 p., e13666.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Culturing Impermanence at the Museum: The Metabolic Collection

    Grünfeld, Martin, 2022, Impermanenc: Exploring continuous change across cultures. Geismar, H., Otto, T. & Warner, C. D. (eds.). University College London Press

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  13. Published

    DNA Methylation and Gene Expression in Blood and Adipose Tissue of Adult Offspring of Women with Diabetes in Pregnancy - A Validation Study of DNA Methylation Changes Identified in Adolescent Offspring

    Manitta, Eleonora, Marques, I. C. F., Bredgaard, S. S., Kelstrup, Louise, Houshmand-Oeregaard, A., Clausen, Tine Dalsgaard, Grunnet, Louise Groth, Mathiesen, Elisabeth, Dalgaard, L. T., Barrès, Romain, Vaag, Allan, Damm, Peter & Hjort, Line, 2022, In: Biomedicines. 10, 6, 15 p., 1244.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    DNA methylation in blood cells is associated with cortisol levels in offspring of mothers who had prenatal post-traumatic stress disorder

    Fransquet, P. D., Hjort, Line, Rushiti, F., Wang, S. J., Krasniqi, S. P., Çarkaxhiu, S. I., Arifaj, D., Xhemaili, V. D., Salihu, M., Leku, N. A. & Ryan, J., 2022, In: Stress and Health. 38, 4, p. 755-766 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

    Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, Asger Bach, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Deciphering inhibitory activity of flavonoids against tau protein kinases: a coupled molecular docking and quantum chemical study

    Rasouli, H., Hosseini Ghazvini, S. M. B., Yarani, R., Altıntaş, Ali, Jooneghani, S. G. N. & Ramalho, T. C., 2022, In: Journal of Biomolecular Structure & Dynamics. 40, 1, p. 411-424 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    DeepFake electrocardiograms: the key for open science for artificial intelligence in medicine

    Thambawita, V., Isaksen, Jonas L., Hicks, S. A., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, N., Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., Holstein-Rathlou, N., Strümke, I., Hammer, H. L., Maleckar, M., Halvorsen, P., Riegler, M. A. & Kanters, Jørgen K., 2022, 17 p. (medRxiv).

    Research output: Working paper › Preprint › Research

  18. Published

    Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome in a Randomized, Controlled Trial

    Ferraz-Bannitz, R., Beraldo, R. A., Peluso, A., Dall, M., Babaei, P., Foglietti, R. C., Martins, L. M., Gomes, P. M., Marchini, J. S., Miguel Suen, V. M., Conti de Freitas, L. C., Navegantes, L. C., Pretti, M. A. M., Boroni, M., Treebak, Jonas Thue, Mori, M. A., Foss, M. C. & Foss-Freitas, M. C., 2022, In: Nutrients. 14, 13, 18 p., 2670.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: A randomised controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Chabanova, E., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, p. 506-517 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Differential Brain and Cerebrospinal Fluid Proteomic Responses to Acute Prenatal Endotoxin Exposure

    Muk (Mudi), Tik, Stensballe, A., Dmytriyeva, O., Brunse, Anders, Jiang, Pingping, Thymann, Thomas, Sangild, Per Torp & Pankratova, Stanislava, 2022, In: Molecular Neurobiology. 59, p. 2204–2218

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., Thomas, L. F., Tin, A., Hoppmann, A., Chu, A. Y., Tayo, B., Thio, C. H. L., Cusi, D., Chai, J-F., Sieber, K. B., Horn, K., Li, M., Scholz, M., Cocca, M., Wuttke, M. & 31 others, van der Most, P. J., Yang, Q., Ghasemi, S., Nutile, T., Li, Y., Pontali, G., Günther, F., Dehghan, A., Correa, A., Parsa, A., Feresin, A., de Vries, A. P. J., Zonderman, A. B., Smith, A. V., Oldehinkel, A. J., De Grandi, A., Rosenkranz, A. R., Franke, A., Teren, A., Metspalu, A., Hicks, A. A., Morris, A. P., Tönjes, A., Morgan, A., Podgornaia, A. I., Christensen, K., Lind, L., Kovacs, P., Rossing, Peter, Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Communications Biology . 5, p. 580 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Discovery of the GI Effects of GLP-1: An Historical Perspective

    Holst, Jens Juul, 2022, In: Digestive Diseases and Sciences. 67, p. 2716-2720

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice

    Breum, Alberte Wollesen, Falk, S., Svendsen, C. S. A., Nicolaisen, T. S., Mathiesen, C. V., Maskos, U. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 7, 9 p., bqac079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Do gene-environment interactions have implications for the precision prevention of type 2 diabetes?

    Sørensen, Thorkild I.A., Metz, Sophia & Kilpeläinen, Tuomas O., 2022, In: Diabetologia. 65, p. 1804–1813 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study

    Koopen, A., Witjes, J., Wortelboer, K., Majait, S., Prodan, A., Levin, E., Herrema, H., Winkelmeijer, M., Aalvink, S., Bergman, J. J. G. H. M., Havik, S., Hartmann, B., Levels, H., Bergh, P-O., van Son, J., Balvers, M., Bastos, D. M., Stroes, E., Groen, A. K., Henricsson, M. & 8 others, Kemper, E. M., Holst, Jens Juul, Strauch, C. M., Hazen, S. L., Backhed, F., De Vos, W. M., Nieuwdorp, M. & Rampanelli, E., 2022, In: Gut. 71, p. 1577-1587 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Dynamic interplay between Afadin S1795 phosphorylation and diet regulates glucose homeostasis in obese mice

    Tozzi, M., Brown, E. L., Petersen, P. S., Lundh, M., Isidor, Marie Sophie, Plucinska, Kaja, Nielsen, Thomas Svava, Agueda Oyarzabal, Marina, Small, Lewin Barkla, Treebak, Jonas Thue & Emanuelli, Brice, 2022, In: The Journal of Physiology. 600, 4, p. 885-902

    Research output: Contribution to journal › Journal article › Research › peer-review

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