Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2017
  2. Published

    Analysis of case-parent trios for imprinting effect using a loglinear model with adjustment for sex-of-parent-specific transmission ratio distortion

    Huang, L. O., Infante-Rivard, C. & Labbe, A., Aug 2017, In: Human Genetics. 136, 8, p. 951-961 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: an individual-based pooled analysis of 40 twin cohorts

    Silventoinen, K., Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y-M., Cozen, W., Hwang, A. E., Mack, T. M., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Tomizawa, R., Pietiläinen, K. H., Rissanen, A., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q. & 82 others, Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Öncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Song, Y., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H., Swan, G. E., Krasnow, R., Magnusson, P. K., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., Lachance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., van Beijsterveldt, C. E., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, Thorkild I.A. & Kaprio, J., Aug 2017, In: The American Journal of Clinical Nutrition. 106, 2, p. 457-466 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Glucose ingestion causes cardiac repolarization disturbances in type 1 long QT syndrome patients and healthy subjects

    Hyltén-Cavallius, L., Iepsen, E. W., Christiansen, M., Graff, C., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Hansen, Torben, Torekov, Signe Sørensen & Kanters, Jørgen K., Aug 2017, In: Heart Rhythm. 14, 8, p. 1165-1170 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Metabolic regulation and the anti-obesity perspectives of human brown fat

    Schéele, Camilla Charlotte Nielsen & Nielsen, S., Aug 2017, In: Redox Biology. 12, p. 770-775 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Ponderal index at birth associates with later risk of gestational diabetes mellitus

    Crusell, Mie Korslund Wiinblad, Damm, Peter, Hansen, Torben, Pedersen, Oluf Borbye, Glümer, C., Vaag, Allan & Lauenborg, J., Aug 2017, In: Archives of Gynecology and Obstetrics. 296, 2, p. 249-256 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The Gut: A Key to the Pathogenesis of Type 2 Diabetes?

    Holst, Jens Juul, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Knop, Filip Krag, Aug 2017, In: Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

    Zillikens, M. C., Demissie, S., Hsu, Y-H., Yerges-Armstrong, L. M., Chou, W-C., Stolk, L., Livshits, G., Broer, L., Johnson, T., Koller, D. L., Kutalik, Z., Luan, J., Malkin, I., Ried, J. S., Smith, A. V., Thorleifsson, G., Vandenput, L., Hua Zhao, J., Zhang, W., Aghdassi, A. & 173 others, Åkesson, K., Amin, N., Baier, L. J., Barroso, I., Bennett, D. A., Bertram, L., Biffar, R., Bochud, M., Boehnke, M., Borecki, I. B., Buchman, A. S., Byberg, L., Campbell, H., Campos Obanda, N., Cauley, J. A., Cawthon, P. M., Cederberg, H., Chen, Z., Cho, N. H., Jin Choi, H., Claussnitzer, M., Collins, F., Cummings, S. R., De Jager, P. L., Demuth, I., Dhonukshe-Rutten, R. A. M., Diatchenko, L., Eiriksdottir, G., Enneman, A. W., Erdos, M., Eriksson, J. G., Eriksson, J., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Garcia, M., Gieger, C., Girke, T., Glazer, N. L., Grallert, H., Grewal, J., Han, B., Hanson, R. L., Hayward, C., Hofman, A., Hoffman, E. P., Homuth, G., Hsueh, W., Hubal, M. J., Hubbard, A., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K., Kilpeläinen, Tuomas O., Klopp, N., Kloth, J. S. L., Koistinen, H. A., Kraus, W. E., Kritchevsky, S., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Launer, L. J., Lee, J., Lerch, M. M., Lewis, J. R., Lind, L., Lindgren, C., Liu, Y., Liu, T., Liu, Y., Ljunggren, Ö., Lorentzon, M., Luben, R. N., Maixner, W., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellström, D., Melov, S., Michaëlsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Newman, A., Nielson, C. M., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Parker, S., Peacock, M., Perola, M., Peters, A., Polasek, O., Prince, R. L., Räikkönen, K., Ralston, S. H., Ripatti, S., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schadt, E. E., Schipf, S., Scott, L., Sehmi, J., Shen, J., Soo Shin, C., Sigurdsson, G., Smith, S., Soranzo, N., Stančáková, A., Steinhagen-Thiessen, E., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Tan, S., Tarnopolsky, M. A., Thompson, P., Thomson, C. A., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Tuomilehto, J., van Schoor, N. M., Verma, A., Vollenweider, P., Völzke, H., Wactawski-Wende, J., Walker, M., Weedon, M. N., Welch, R., Wichmann, H., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Xie, W., Yu, L., Zhou, Y., Chambers, J. C., Döring, A., van Duijn, C. M., Econs, M. J., Gudnason, V., Kooner, J. S., Psaty, B. M., Spector, T. D., Stefansson, K., Rivadeneira, F., Uitterlinden, A. G., Wareham, N. J., Ossowski, V., Waterworth, D., Loos, R. J. F., Karasik, D., Harris, T. B., Ohlsson, C. & Kiel, D. P., 19 Jul 2017, In: Nature Communications. 8, 13 p., 80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

    Willems, S. M., et al., E. A., Grarup, N., Linneberg, Allan René, Schnurr, T. M., Pedersen, Oluf Borbye, GEFOS Any-Type of Fracture Consortium, G. A. O. F. C. & Hansen, Torben, 12 Jul 2017, In: Nature Communications. 8, 12 p., 16015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Putting the brain in its place

    Whiteley, Louise, 7 Jul 2017, In: Times Higher Education. p. 42-43 2 p.

    Research output: Contribution to journalLiterature reviewCommunication

  11. Published

    Effect of Liraglutide Treatment on Prediabetes and Overweight or Obesity in Clozapine- or Olanzapine-Treated Patients With Schizophrenia Spectrum Disorder: A Randomized Clinical Trial

    Larsen, J. R., Vedtofte, L., Jakobsen, M. S. L., Jespersen, H. R., Jakobsen, M. I., Svensson, C. K., Koyuncu, K., Schjerning, O., Oturai, P. S., Kjær, Andreas, Nielsen, J., Holst, Jens Juul, Ekstrøm, Claus Thorn, Correll, C. U., Vilsbøll, Tina & Fink-Jensen, Anders, 1 Jul 2017, In: J A M A Psychiatry. 74, 7, p. 719-728 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The effect of a subcutaneous infusion of GLP-1, OXM and PYY on Energy intake and Expenditure in Obese volunteers

    Tan, T., Behary, P., Tharakan, G., Minnion, J., Al-Najim, W., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Bloom, S. R., 1 Jul 2017, In: The Journal of clinical endocrinology and metabolism. 102, 7, p. 2364-2372 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cyp3a11 is not essential for the formation of murine bile acids

    Wahlström, A., Al-Dury, S., Ståhlman, M., Bäckhed, F. & Marschall, H., Jul 2017, In: Biochemistry and Biophysics Reports. 10, p. 70-75 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

    Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Gq and Gs signaling acting in synergy to control GLP-1 secretion

    Pedersen, M. H., Ekberg, J. H., Engelstoft, M. S., Timshel, P., Madsen, A. N. & Schwartz, Thue W., Jul 2017, In: Molecular and Cellular Endocrinology. 449, p. 64-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

    Alm, P. S., de Castro Barbosa, T., Barrès, Romain, Krook, A. & Zierath, Juleen R, Jul 2017, In: Molecular Metabolism. 6, 7, p. 621-630 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life

    Bjerregaard, L. G., Jensen, B. W. & Baker, J. L., Jul 2017, In: Paediatric and Perinatal Epidemiology. 31, 4, p. 284-292 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

    Wu, H., Esteve, E., Tremaroli, V., Khan, M. T., Caesar, R., Mannerås-Holm, L., Ståhlman, M., Olsson, L. M., Serino, M., Planas-Fèlix, M., Xifra, G., Mercader, J. M., Torrents, D., Burcelin, R., Ricart, W., Perkins, R., Fernàndez-Real, J. M. & Bäckhed, F., Jul 2017, In: Nature Medicine. 23, 7, p. 850-858 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia

    Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag, Glenthøj, Birte Yding & Ebdrup, Bjørn, Jul 2017, In: Acta Psychiatrica Scandinavica. 136, 1, p. 52-62

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals

    Canfora, E. E., van der Beek, C. M., Hermes, G. D. A., Goossens, G. H., Jocken, J. W. E., Holst, Jens Juul, van Eijk, H. M., Venema, K., Smidt, H., Zoetendal, E. G., Dejong, C. H. C., Lenaerts, K. & Blaak, E. E., Jul 2017, In: Gastroenterology. 153, 1, p. 87-97.e3

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect

    Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    ‘The house’ as a framing device for public engagement in STEM museums

    Whiteley, Louise, Stenslund, A., Arnold, Ken & Söderqvist, Thomas, Jul 2017, In: Museum & Society. 15, 2, p. 217-235 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Sociodemographic characteristics of nonparticipants in the Danish colorectal cancer screening program: A nationwide cross-sectional study

    Larsen, Mette, Mikkelsen, E. M., Rasmussen, M., Friis-Hansen, Lennart Jan, Ovesen, A. U., Rahr, H. B. & Andersen, B., 27 Jun 2017, In: Clinical Epidemiology. 9, p. 345-354 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Regulation of glycolysis in brown adipocytes by HIF-1α

    Basse, A. L., Isidor, Marie Sophie, Winther, Sally, Skjoldborg, N. B., Murholm, M., Andersen, E. S., Pedersen, S. B., Wolfrum, C., Quistorff, B. & Hansen, Jacob B., 22 Jun 2017, In: Scientific Reports. 7, 15 p., 4052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men

    Sahl, Ronni Eg, Andersen, P. R., Gronbaek, K., Morville, T. H., Rosenkilde, M., Rasmusen, H. K., Poulsen, Steen Seier, Prats Gavalda, Clara, Dela, Flemming & Helge, Jørn Wulff, 22 Jun 2017, In: Frontiers in Physiology. 8, 6 p., 407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Discovery of novel heart rate-associated loci using the Exome Chip

    van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., Lyytikäinen, L-P. & 101 others, Hall, L. M., van Setten, J., Trompet, S., Prins, B. P., Isaacs, A., Radmanesh, F., Marten, J., Entwistle, A., Kors, J. A., Silva, C. T., Alonso, A., Bis, J. C., de Boer, R. A., de Haan, H. G., de Mutsert, R., Dedoussis, G., Dominiczak, A. F., Doney, A. S. F., Ellinor, P. T., Eppinga, R. N., Felix, S. B., Guo, X., Hagemeijer, Y., Hansen, Torben, Harris, T. B., Heckbert, S. R., Huang, P. L., Hwang, S., Kähönen, M., Kanters, Jørgen K., Kolcic, I., Launer, L. J., Li, M., Yao, X. J., Linneberg, Allan René, Liu, S., Macfarlane, P. W., Mangino, M., Morris, A. D., Mulas, A., Murray, A. D., Nelson, C. P., Orrù, M., Padmanabhan, S., Peters, A., Porteous, D. J., Poulter, N., Psaty, B. M., Qi, L., Raitakari, O. T., Rivadeneira, F., Roselli, C., Rudan, I., Sattar, N., Sever, P., Sinner, M. F., Soliman, E. Z., Spector, T. D., Stanton, A. V., Stirrups, K. E., Taylor, K. D., Tobin, M. D., Uitterlinden, A., Vaartjes, I., Hoes, A. W., van der Meer, P., Völker, U., Waldenberger, M., Xie, Z., Zoledziewska, M., Tinker, A., Polasek, O., Rosand, J., Jamshidi, Y., van Duijn, C. M., Zeggini, E., Jukema, J. W., Asselbergs, F. W., Samani, N. J., Lehtimäki, T., Gudnason, V., Wilson, J., Lubitz, S. A., Kääb, S., Sotoodehnia, N., Caulfield, M. J., Palmer, C. N. A., Sanna, S., Mook-Kanamori, D. O., Deloukas, P., Pedersen, Oluf Borbye, Rotter, J. I., Dörr, M., O'Donnell, C. J., Hayward, C., Arking, D. E., Kooperberg, C., van der Harst, P., Eijgelsheim, M., Stricker, B. H. C. & Munroe, P. B., 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Sociomics: Using Omic Approaches to Understand Social Evolution

    Ghoul, M., Andersen, Sandra Breum & West, S. A., 1 Jun 2017, In: Trends in Genetics. 33, 6, p. 408-419 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Dietary Assessment in the MetaCardis Study: Development and Relative Validity of an Online Food Frequency Questionnaire

    Verger, E. O., Armstrong, P., Nielsen, T., Chakaroun, R., Aron-Wisnewsky, J., Gøbel, R. J., Schütz, T., Delaere, F., Gausseres, N., Clément, K., Holmes, B. A. & MetaCardis Consortium, M. C., Jun 2017, In: Journal of the Academy of Nutrition and Dietetics. 117, 6, p. 878-888 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men

    Matikainen, N., Söderlund, S., Björnson, E., Bogl, L. H., Pietiläinen, K. H., Hakkarainen, A., Lundbom, N., Eliasson, B., Räsänen, S. M., Rivellese, A., Patti, L., Prinster, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., Jun 2017, In: Nutrition, Metabolism & Cardiovascular Diseases. 27, 6, p. 534-542 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Neonatal Vitamin D Levels in Relation to Risk of Overweight at 7 Years in the Danish D-Tect Case-Cohort Study

    Jensen, C. B., Lundqvist, M., Sørensen, Thorkild I.A. & Heitmann, Berit, Jun 2017, In: Obesity Facts. 10, 3, p. 273-283 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Quality of life improves in children and adolescents during a community-based overweight and obesity treatment

    Mollerup, P. M., Nielsen, T. R. H., Bøjsøe, C., Kloppenborg, J. T., Baker, J. L. & Holm, Jens-Christian, Jun 2017, In: Quality of Life Research. 26, 6, p. 1597-1608

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions

    Shungin, D., Deng, W. Q., Varga, T. V., Luan, J., Mihailov, E., Metspalu, A., Morris, A. P., Forouhi, N. G., Lindgren, C., Magnusson, P. K. E., Pedersen, N. L., Hallmans, G., Chu, A. Y., Justice, A. E., Graff, M., Winkler, T. W., Rose, L. M., Langenberg, C., Cupples, L. A., Ridker, P. M. & 11 others, Wareham, N. J., Ong, K. K., Loos, R. J. F., Chasman, D. I., Ingelsson, E., Kilpeläinen, Tuomas O., Scott, R. A., Mägi, R., Paré, G., Franks, P. W. & GIANT Consortium, G. C., Jun 2017, In: P L o S Genetics. 13, 6, 15 p., e1006812.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Reference values for fasting serum resistin in healthy children and adolescents

    Lausten-Thomsen, U., Christiansen, M., Hedley, P. L., Nielsen, T. R. H., Fonvig, Cilius Esmann, Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, Jun 2017, In: Clinica Chimica Acta. 469, p. 161-165 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Selection in Europeans on fatty acid desaturases associated with dietary changes

    Buckley, M. T., Racimo, Fernando, Allentoft, Morten Erik, Jensen, M. K., Jonsson, Anna Elisabet, Huang, H., Hormozdiari, F., Sikora, Martin, Marnetto, D., Eskin, E., Jørgensen, M. E., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Kraft, P., Willerslev, Eske & Nielsen, Rasmus, Jun 2017, In: Molecular Biology and Evolution. 34, 6, p. 1307-1318 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Variability in response to albuminuria-lowering drugs: true or random?

    Petrykiv, S. I., de Zeeuw, D., Persson, F., Rossing, Peter, Gansevoort, R. T., Laverman, G. D. & Heerspink, H. J. L., Jun 2017, In: British Journal of Clinical Pharmacology. 83, 6, p. 1197-1204 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Health care professionals from developing countries report educational benefits after an online diabetes course

    Albrechtsen, Nicolai Jacob Wewer, Poulsen, K. W., Svensson, L. Ø., Jensen, Lasse X, Holst, Jens Juul & Torekov, Signe Sørensen, 31 May 2017, In: B M C Medical Education. 17, 8 p., 97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis

    DeZwaan-McCabe, D., Sheldon, R. D., Gorecki, M. C., Guo, D., Gansemer, E. R., Kaufman, R. J., Rahmouni, K., Gillum, M. P., Taylor, E. B., Teesch, L. M. & Rutkowski, D. T., 30 May 2017, In: Cell Reports. 19, 9, p. 1794-1806 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

    Väremo, L., Henriksen, T. I., Schéele, Camilla Charlotte Nielsen, Broholm, C., Pedersen, M., Uhlén, M., Pedersen, Bente Klarlund & Nielsen, J., 25 May 2017, In: Genome Medicine. 9, 12 p., 47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

    Canfora, E. E., van der Beek, C. M., Jocken, J. W. E., Goossens, G. H., Holst, Jens Juul, Olde Damink, S. W. M., Lenaerts, K., Dejong, C. H. C. & Blaak, E. E., 24 May 2017, In: Scientific Reports. 7, 12 p., 2360.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Chronic intrahypothalamic rather than subcutaneous liraglutide treatment reduces body weight gain and stimulates the melanocortin receptor system

    Kaineder, K., Birngruber, T., Rauter, G., Obermüller, B., Eichler, J., Münzker, J., Al-Zoughbi, W., Mautner, S. I., Torekov, Signe Sørensen, Hartmann, Bolette, Kotzbeck, P. & Pieber, T. R., 16 May 2017, In: International Journal of Obesity. 41, p. 1263-1270 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Voigt, A. Y., Vestergaard, H., Hercog, R., Costea, P. I., Kultima, J. R., Li, J., Jørgensen, T., Levenez, F. & 10 others, Doré, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Ehrlich, S. D., Bork, P., Pedersen, Oluf Borbye & MetaHIT consortium, M. C., 3 May 2017, In: Nature. 545, 116, 1 p., 22318.

    Research output: Contribution to journalComment/debateResearch

  42. Published

    The Limits of Exercise Physiology: From Performance to Health

    Gabriel, B. M. & Zierath, Juleen R, 2 May 2017, In: Cell Metabolism. 25, 5, p. 1000-1011 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Cardiorespiratory Fitness and Adiposity as Determinants of Metabolic Health-Pooled Analysis of Two Twin Cohorts

    Jukarainen, S., Holst, R., Dalgård, C., Piirilä, P., Lundbom, J., Hakkarainen, A., Lundbom, N., Rissanen, A., Kaprio, J., Kyvik, K. O., Sørensen, Thorkild I.A. & Pietiläinen, K. H., 1 May 2017, In: The Journal of clinical endocrinology and metabolism. 102, 5, p. 1520-1528 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials

    Hansen, M., Sonne, David Peick, Mikkelsen, K. H., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2017, In: Journal of Diabetes and its Complications. 31, 5, p. 918-927 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Combined immunotherapy for advanced prostate cancer: Empowering the T cell army.

    Suleman, Sufyan & Wei, G., May 2017, In: Asian Journal of Urology.

    Research output: Contribution to journalJournal articleCommunication

  46. Published

    Dietary intake and adipose tissue content of long-chain n-3 PUFAs and subsequent 5-y change in body weight and waist circumference

    Jakobsen, M. U., Madsen, L., Skjøth, F., Berentzen, T. L., Halkjaer, J., Tjønneland, A., Schmidt, E. B., Sørensen, Thorkild I.A., Kristiansen, Karsten & Overvad, K., May 2017, In: The American Journal of Clinical Nutrition. 105, 5, p. 1148-1157 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effect of oral contraceptives and/or metformin on GLP-1 secretion and reactive hypoglycaemia in polycystic ovary syndrome

    Glintborg, D., Mumm, H., Holst, Jens Juul & Andersen, M., May 2017, In: Endocrine Connections. 6, 4, p. 267-277 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effects of isomaltulose and high amounts of PUFAs together with elevated physical activity on subjects with a moderate metabolic risk profile before and after a 6-weeks randomized lifestyle intervention trial

    Metz, Sophia, Kabisch, S. & Pfeiffer, A. F. H., May 2017, In: Diabetologie und Stoffwechsel. 12, S 01, p. S1-S84

    Research output: Contribution to journalConference abstract in journalResearch

  49. Published

    Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes

    Dejgaard, T. F., Johansen, N. B., Frandsen, C. S. S., Asmar, A., Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., May 2017, In: Diabetes, Obesity and Metabolism. 19, 5, p. 734–738

    Research output: Contribution to journalLetterResearchpeer-review

  50. Published

    Glycaemic control and weight loss with semaglutide in type 2 diabetes

    Madsbad, Sten & Holst, Jens Juul, May 2017, In: The Lancet Diabetes and Endocrinology. 5, 5, p. 315-317 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  51. Published

    Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition

    Feng, Y., Demehri, F. R., Xiao, W., Tsai, Y., Jones, J. C., Brindley, C. D., Threadgill, D. W., Holst, Jens Juul, Hartmann, Bolette, Barrett, T. A., Teitelbaum, D. H. & Dempsey, P. J., May 2017, In: Cellular and Molecular Gastroenterology and Hepatology. 3, 3, p. 447-468 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published
  53. Published

    Reference intervals for C-peptide and insulin derived from a general adult Danish population

    Larsen, P. B., Linneberg, Allan René, Hansen, Torben & Friis-Hansen, L. J., May 2017, In: Clinical Biochemistry. 50, 7-8, p. 408-413

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

    Lynes, M. D., Leiria, L. O., Lundh, M., Bartelt, A., Shamsi, F., Huang, T. L., Takahashi, H., Hirshman, M. F., Schlein, C., Lee, A., Baer, L. A., May, F. J., Narain, N. R., Chen, E. Y., Kiebish, M. A., Cypess, A. M., Blüher, M., Goodyear, L. J., Hotamisligil, G. S., Stanford, K. I. & 1 others, Tseng, Y., May 2017, In: Nature Medicine. 23, 5, p. 631-637 7 p.

    Research output: Contribution to journalLetterResearchpeer-review

  55. Published

    25(OH)D levels in trained versus sedentary university students at 64° north

    Jerome, S., Sticka, K., Schnurr, T. M., Magnum, S., Reynolds, A. & Dunlap , K. L., 28 Apr 2017, In: International Journal of Circumpolar Health. 76, 1, 8 p., 1314414.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Dyslipidemia and reference values for fasting plasma lipid concentrations in Danish/North-European White children and adolescents

    Nielsen, T. R. H., Lausten-Thomsen, U., Fonvig, Cilius Esmann, Bøjsøe, C., Pedersen, L., Bratholm, P. S., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 28 Apr 2017, In: B M C Pediatrics. 17, 11 p., 116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Exploring the Behavioral and Metabolic Phenotype Generated by Re-Introduction of the Ghrelin Receptor in the Ventral Tegmental Area

    Skov, Louise Julie, Jensen, M., Christiansen, S. H., Ratner, C., Woldbye, David Paul Drucker & Holst, Birgitte, 26 Apr 2017, In: International Journal of Molecular Sciences. 18, 5, 17 p., 914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K. L., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A. & 297 others, Renström, F., Wu, J. C., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg-Gresham, J. L., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, Johanne Marie, Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E. P., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., De Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, Torben, Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L. A., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J., Jarvelin, M. R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, Allan René, Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., Mckenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. B., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T. K., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H. J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, Oluf Borbye, Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, Thorkild I.A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., drb459, drb459, Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J. L., Loos, R. J. F., Kilpeläinen, Tuomas O., Liu, C., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, 19 p., 14977.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

    Rocha, N., Bulger, D. A., Frontini, A., Titheradge, H., Gribsholt, S. B., Knox, R., Page, M., Harris, J., Payne, F., Adams, C., Sleigh, A., Crawford, J., Gjesing, A. P., Bork-Jensen, J., Pedersen, O., Barroso, I., Hansen, T., Cox, H., Reilly, M., Rossor, A. & 11 others, Brown, R. J., Taylor, S. I., McHale, D., Armstrong, M., Oral, E. A., Saudek, V., O'Rahilly, S., Maher, E. R., Richelsen, B., Savage, D. B. & Semple, R. K., 19 Apr 2017, In: eLife. 6, 27 p., e23813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Age at Menarche and Risk of Multiple Sclerosis: A Prospective Cohort Study Based on the Danish National Birth Cohort

    Nielsen, N. M., Harpsøe, M., Simonsen, J., Stenager, E., Magyari, M., Koch-Henriksen, N., Baker, J. L., Hjalgrim, H., Frisch, M. & Bager, P., 15 Apr 2017, In: American Journal of Epidemiology. 185, 8, p. 712-719 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Childhood Body Size and the Risk of Malignant Melanoma in Adulthood

    Meyle, K. D., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 15 Apr 2017, In: American Journal of Epidemiology. 185, 8, p. 673-680 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

    Xiao, L., Sonne, S. B., Feng, Q., Chen, N., Xia, Z., Li, X., Fang, Z., Zhang, D., Fjære, E., Midtbø, L. K., Derrien, M., Hugenholtz, F., Tang, L., Li, J., Zhang, J., Liu, C., Hao, Q., Vogel, U. B., Mortensen, A., Kleerebezem, M. & 8 others, Licht, T. R., Yang, H., Wang, J., Li, Y., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 8 Apr 2017, In: Microbiome. 5, 12 p., 43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    GPCR-Mediated Signaling of Metabolites

    Husted, Anna Sofie, Trauelsen, Mette, Rudenko, Olga, Hjorth, Siv Annegrethe & Schwartz, Thue W., 4 Apr 2017, In: Cell Metabolism. 25, 4, p. 777-796 20 p.

    Research output: Contribution to journalReviewResearchpeer-review

  64. Published

    Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D. & 34 others, Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, Johanne Marie, Kleber, M. E., Hollensted, M., Aadahl, Mette, Færch, K., Grarup, N., drb459, drb459, Sørensen, Thorkild I.A., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye, Loos, Ruth, Kilpeläinen, Tuomas O., CHARGE Consortium, C. C., EPIC-InterAct Consortium, E. C. & PAGE Consortium, P. C., 1 Apr 2017, In: PLOS Genetics. 13, 4, e1006528.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Insulin and Glucagon: Partners for Life

    Holst, Jens Juul, Holland, W., Gromada, J., Lee, Y., Unger, R. H., Yan, H., Sloop, K. W., Kieffer, T. J., Damond, N. & Herrera, P. L., 1 Apr 2017, In: Endocrinology. 158, 4, p. 696-701 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  66. Published

    Body mass index trajectories from 2 to 18 years - exploring differences between European cohorts

    Graversen, L., Howe, L. D., Sørensen, Thorkild I.A., Sovio, U., Hohwü, L., Tilling, K., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M. & Obel, C., Apr 2017, In: Pediatric Obesity. 12, 2, p. 102-109 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects

    Westberg-Rasmussen, S., Starup-Linde, J., Hermansen, K., Holst, Jens Juul, Hartmann, Bolette, Vestergaard, P. & Gregersen, S., Apr 2017, In: Bone. 97, p. 261-266 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Intensified multifactorial intervention in type 2 diabetics with microalbuminuria leads to long-term renal benefits

    Oellgaard, J., Gæde, P., Rossing, Peter, Persson, F., Parving, H. & Pedersen, Oluf Borbye, Apr 2017, In: Kidney International. 91, 4, p. 982-988 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled trial

    Mobini, R., Tremaroli, V., Ståhlman, M., Karlsson, F., Levin, M., Ljungberg, M., Sohlin, M., Bertéus Forslund, H., Perkins, R., Bäckhed, G. F. & Jansson, P., Apr 2017, In: Diabetes, Obesity and Metabolism. 19, 4, p. 579-589 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

    Castillo-Fernandez, J. E., Loke, Y. J., Bass-Stringer, S., Gao, F., Xia, Y., Wu, H., Lu, H., Liu, Y., Wang, J., Spector, T. D., Saffery, R., Craig, J. M. & Bell, J. T., 24 Mar 2017, In: Genome Medicine. 9, 15 p., 28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition

    Huang, Yun, Kim, J. K., Do, D. V., Lee, C., Penfold, C. A., Zylicz, Jan Jakub, Marioni, J. C., Hackett, J. A. & Surani, M. A., 21 Mar 2017, In: eLife. 6, e22345.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Liraglutide as adjunct to insulin treatment in type 1 diabetes does not interfere with glycaemic recovery or gastric emptying rate during hypoglycaemia: a randomised, placebo-controlled, double-blind, parallel-group study

    Frandsen, C. S., Dejgaard, T. F., Andersen, H. U., Holst, Jens Juul, Hartmann, Bolette, Thorsteinsson, B. & Madsbad, Sten, 17 Mar 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 773-782 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Impact of gain-of-function mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) on glucose and lipid homeostasis

    Foer, D., Zhu, M., Cardone, R. L., Simpson, C., Sullivan, R., Nemiroff, S., Lee, G., Kibbey, R. G., Petersen, K. M. F. & Insogna, K. L., 10 Mar 2017, In: Osteoporosis International. 28, 6, p. 2011-17 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Glucose-dependent insulinotropic polypeptide promotes lipid deposition in subcutaneous adipocytes in obese type 2 diabetes patients: a maladaptive response

    Thondam, S. K., Daousi, C., Wilding, J. P. H., Holst, Jens Juul, Ameen, G. I., Yang, C., Whitmore, C., Mora, S. & Cuthbertson, D. J., 1 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E224-E233

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Microbiota-induced obesity requires farnesoid X receptor

    Parséus, A., Sommer, N., Sommer, F., Caesar, R., Molinaro, A., Ståhlman, M., Greiner, T. U., Perkins, R. & Bäckhed, G. F., 1 Mar 2017, In: Gut. 66, 3, p. 429-437 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Roles of RFRP-3 in the Daily and Seasonal Regulation of Reproductive Activity in Female Syrian Hamsters

    Henningsen, J. B., Ancel, C., Mikkelsen, Jens D., Gauer, F. & Simonneaux, V., 1 Mar 2017, In: Endocrinology. 158, 3, p. 652-663 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Short communication: Promotion of glucagon-like peptide-2 secretion in dairy calves with a bioactive extract from Olea europaea

    Morrison, S. Y., Pastor, J. J., Quintela, J. C., Holst, Jens Juul, Hartmann, Bolette, Drackley, J. K. & Ipharraguerre, I. R., 1 Mar 2017, In: Journal of Dairy Science. 100, 3, p. 1940-1945 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents

    Dahl, M., Ohrt, J. D., Fonvig, C. E., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 1 Mar 2017, In: JCRPE Journal of Clinical Research in Pediatric Endocrinology. 9, 1, p. 8-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    The lack of natural processes of delivery and neonatal intensive care treatment lead to impaired cytokine responses later in life

    Martikainen, M. V., Keski-Nisula, L., Jakupovic, Hermina, Karvonen, A. M., Pekkanen, J., Hirvonen, M. R. & Roponen, M., 1 Mar 2017, In: American Journal of Reproductive Immunology. 77, 3, e12621.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    A molecular census of arcuate hypothalamus and median eminence cell types

    Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, Tune H, Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., Rosen, E. D., Lowell, B. B. & Tsai, L. T., Mar 2017, In: Nature Neuroscience. 20, 3, p. 484-496 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone

    Ahluwalia, Tarun Veer Singh, Troelsen, J. T., Balslev-Harder, M., Bork-Jensen, J., Thuesen, B. H., Cerqueira, C., Linneberg, Allan René, Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben & Dalgaard, L. T., Mar 2017, In: Journal of Medical Genetics. 54, 3, p. 166-175 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

    Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor Signalling

    Wahlström, A., Kovatcheva-Datchary, P., Ståhlman, M., Bäckhed, F. & Marschall, H. U., Mar 2017, In: Digestive Diseases. 35, 3, p. 246-250 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Efficacy and safety of fixed-ratio combination of insulin degludec and liraglutide (IDegLira) for the treatment of type 2 diabetes

    Vedtofte, L., Knop, Filip Krag & Vilsbøll, Tina, Mar 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 387-396 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  85. Published

    Exhibiting health and medicine as culture

    Whiteley, Louise, Tybjerg, Karin, Pedersen, B. V., Bencard, Adam & Arnold, Ken, Mar 2017, In: Public Health Panorama. 3, 1, p. 59-68 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle

    Mudry, J. M., Lassiter, D. G., Nylén, C., García-Calzón, S., Näslund, E., Krook, A. & Zierath, Juleen R, Mar 2017, In: Diabetes. 66, 3, p. 651-662

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Normal values of regional left ventricular myocardial thickness, mass and distribution-assessed by 320-detector computed tomography angiography in the Copenhagen General Population Study

    Hindsø, L., Fuchs, A., Kühl, J. T., Nilsson, E. J. P., Sigvardsen, P. E., Køber, Lars Valeur, Nordestgaard, Børge & Kofoed, Klaus Fuglsang, Mar 2017, In: International Journal of Cardiovascular Imaging. 33, 3, p. 421–429

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial

    Garcia-Perez, I., Posma, J. M., Gibson, R., Chambers, E. S., Hansen, T. H., drb459, drb459, Hansen, Torben, Beckmann, M., Pedersen, Oluf Borbye, Elliott, P., Stamler, J., Nicholson, J. K., Draper, J., Mathers, J. C., Holmes, E. & Frost, G., Mar 2017, In: The Lancet Diabetes & Endocrinology. 5, 3, p. 184-195 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

    Chursa, U., Nuñez-Durán, E., Cansby, E., Amrutkar, M., Sütt, S., Ståhlman, M., Olsson, B., Borén, J., Johansson, M. E., Bäckhed, G. F., Johansson, B. R., Sihlbom, C. & Mahlapuu, M., Mar 2017, In: Diabetologia. 60, 3, p. 553-567 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

    Brier, A. B., Loft, A., Madsen, J. G. S., Rosengren, T., Nielsen, R., Schmidt, S. F., Liu, Z., Yan, Q., Gronemeyer, H. & Mandrup, S., 28 Feb 2017, In: Nucleic Acids Research. 45, 4, p. 1743-1759 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance

    Grünberg, J. R., Hoffmann, J. M., Hedjazifar, S., Nerstedt, A., Jenndahl, L., Elvin, J., Castellot, J., Wei, L., Movérare-Skrtic, S., Ohlsson, C., Holm, L. M., Bäckhed, G. F., Syed, I., Bosch, F., Saghatelian, A., Kahn, B. B., Hammarstedt, A. & Smith, U., 27 Feb 2017, In: Scientific Reports. 7, 15 p., 43515.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins

    pjx571, pjx571, Hansen, T. H., Mahendran, Y., Pyl, P., Galijatovic, E. A. A., Jonsson, Anna Elisabet, Gjesing, A., Linneberg, Allan René, Jørgensen, T., Hansen, Torben & drb459, drb459, 21 Feb 2017, In: Scientific Reports. 7, 8 p., 43128.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels

    Mahendran, Y., Jonsson, Anna Elisabet, Have, C. T., Allin, K. H., Witte, D. R., Jørgensen, M. E., Grarup, N., Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 10 Feb 2017, In: Diabetologia. 60, 5, p. 873-878 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Rare and low-frequency coding variants alter human adult height

    Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G., Aben, K. K., Allin, K. H., Appel, E. V., Bang, L. E., Benn, Marianne, Bork-Jensen, J., Frikke-Schmidt, Ruth, Grarup, N., Hansen, Torben, Hollensted, M., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, Allan René, Nielsen, S. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, Tybjærg-Hansen, Anne, drb459, drb459, Pers, Tune H & EPIC-InterAct Consortium, E. C., 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats

    Hankir, M. K., Seyfried, F., Hintschich, C. A., Diep, T., Kleberg, K., Kranz, M., Deuther-Conrad, W., Tellez, L. A., Rullmann, M., Patt, M., Teichert, J., Hesse, S., Sabri, O., Brust, P., Hansen, Harald S., de Araujo, I. E., Krügel, U. & Fenske, W. K., 7 Feb 2017, In: Cell Metabolism. 25, 2, p. 335-344 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: A randomized controlled trial in patients with type 2 diabetes

    Nauck, M. A., Kahle, M., Baranov, O., Deacon, Carolyn F. & Holst, Jens Juul, 6 Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 200-207 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Displaying the researched body: Growing cell portraits in a medical museum

    Whiteley, Louise, Tybjerg, Karin & Pedersen, B. V., 1 Feb 2017, In: Leonardo & Leonardo Music Journal. 50, 1, p. 86-87 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

    Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., Moldovan, M., van Iperen, E., Hovingh, G. K., Demuth, I., Norman, K., Steinhagen-Thiessen, E., Demuth, J., Bertram, L., Liu, T., Coassin, S. & 31 others, Willeit, J., Kiechl, S., Willeit, K., Mason, D., Wright, J., Morris, R., Wanamethee, G., Whincup, P., Ben-Shlomo, Y., McLachlan, S., Price, J. F., Kivimaki, M., Welch, C., Sanchez-Galvez, A., Marques-Vidal, P., Nicolaides, A., Panayiotou, A. G., Onland-Moret, N. C., van der Schouw, Y. T., Matullo, G., Fiorito, G., Guarrera, S., Sacerdote, C., Wareham, N. J., Langenberg, C., Scott, R., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René & LifeLines Cohort study group, L. C. S. G., Feb 2017, In: The Lancet Diabetes & Endocrinology. 5, 2, p. 97–105

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Acute effects of glucagon-like peptide-1, GLP-19-36 amide, and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers

    Hansen, Lasse Bremholm, Andersen, U. B., Hornum, Mads, Hilsted, L., Veedfald, S., Hartmann, Bolette & Holst, Jens Juul, Feb 2017, In: Physiological Reports. 5, 4, 12 p., e13102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass

    Nielsen, S., Svane, M. S., Kuhre, Rune Ehrenreich, Clausen, T. R., Kristiansen, V. B., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Cohort description: The Danish study of Functional Disorders

    Dantoft, T. M., Ebstrup, J. F., Linneberg, Allan René, Skovbjerg, S., Madsen, A. L., Mehlsen, J., Brinth, L., Eplov, L. F., Carstensen, T. W., Schroder, A., Fink, P. K., Mortensen, Erik Lykke, Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., Feb 2017, In: Clinical Epidemiology. 9, p. 127-139 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review