Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2017
  2. Published

    Self-Reported Versus Accelerometer-Assessed Daily Physical Activity in Childhood Obesity Treatment

    Schnurr, T. M., Bech, B., Haarmark Nielsen, T. R., Andersen, I. G., Hjorth, Mads Fiil, Aadahl, Mette, Fonvig, Cilius Esmann, Hansen, Torben & Holm, Jens-Christian, 2017, In: Perceptual and Motor Skills. 124, 4, p. 795-811 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

    Sørensen, L. M., Jensen, J. M., Petersen, B., Sibbesen, J. A., Liu, S., Villesen, P., Skov, L., Belling, K. G., Have, C. T., Izarzugaza, J. M. G., Grosjean, M., Bork-Jensen, J., Grove, J., Als, T. D., Huang, S., Chang, Y., Xu, R., Ye, W., Rao, J., Guo, X. & 39 others, Sun, J., Cao, H., Ye, C., van Beusekom, J., Espeseth, T., Flindt, E., Friborg, R. M., Halager, A. E., Le Hellard, S., Hultman, C. M., Lescai, F., Li, S., Lund, O., Løngren, P., Mailund, T., Matey-Hernandez, M. L., Mors, O., Pedersen, C. N. S., Sicheritz-Pontén, T., Sullivan, P., Syed, A., Westergaard, D., Yadav, R., Li, N., Xu, X., Hansen, Torben, Krogh, Anders, Bolund, L., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Gupta, R., Rasmussen, Simon, Besenbacher, S., Børglum, A. D., Wang, J., Eiberg, Hans Rudolf Lytchoff, Kristiansen, Karsten, Brunak, Søren & Schierup, M. H., 2017, In: Nature. 548, 7665, p. 87-91 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  4. Published

    Shared genetic variants suggest common pathways in allergy and autoimmune diseases

    Kreiner, E., Waage, J., Standl, M., Brix, S., Pers, T. H., Couto Alves, A., Warrington, N. M., Tiesler, C. M., Fuertes, E., Franke, L., Hirschhorn, J. N., James, A., Simpson, A., Tung, J. Y., Koppelman, G. H., Postma, D. S., Pennell, C. E., Jarvelin, M-R., Custovic, A., Timpson, N. & 6 others, Ferreira, M. A., Strachan, D. P., Henderson, J., Hinds, D., Bisgaard, H. & Bønnelykke, Klaus, 2017, In: The Journal of allergy and clinical immunology. 140, 3, p. 771-781

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Should Europe follow the US and declare obesity a disease? A discussion of the so-called utilitarian argument

    Vallgårda, Signild, Nielsen, Morten Ebbe Juul, Hansen, A. K. K., Ó Cathaoir, Katharina, Hartlev, Mette, Holm, Lotte, Christensen, Bodil Just, Jensen, Jørgen Dejgård, Sørensen, Thorkild I.A. & Sandøe, Peter, 2017, In: European Journal of Clinical Nutrition. 71, p. 1263–1267 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Single-molecule analysis of ligand efficacy in β2AR-G-protein activation

    Gregorio, G. G., Masureel, M., Hilger, D., Terry, D. S., Juette, M., Zhao, H., Zhou, Z., Perez-Aguilar, J. M., Hauge, M., Mathiasen, Signe, Javitch, J. A., Weinstein, H., Kobilka, B. K. & Blanchard, S. C., 2017, In: Nature. 547, 7661, p. 68–73

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Smallpox and BCG vaccination and HIV-1 in Guinea-Bissau and Denmark

    Rieckmann, A., Villumsen, M., Jensen, M. L., Ravn, H., da Silva, Z. J., Sørup, S., Baker, J. L., Rodrigues, A., Benn, C. S., Roth, A. E. & Aaby, P., 2017, In: Tropical Medicine & International Health. 22, S1, p. 63-64 2 p., 4S7.5.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  8. Published

    Structural biology: Full monty of family B GPCRs

    Schwartz, Thue W. & Frimurer, Thomas Michael, 2017, In: Nature Chemical Biology. 13, 8, p. 819-821

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Structure-based discovery of novel US28 small molecule ligands with different modes of action

    Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes

    DIRECT consortium group, D. C. G., 2017, In: Diabetes, Obesity and Metabolism. 19, 3, p. 356-363 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Sweet Taste Receptor Activation in the Gut Is of Limited Importance for Glucose-Stimulated GLP-1 and GIP Secretion

    Saltiel, M. Y., Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Eliasen, R., Conde-Frieboes, K. W., Rosenkilde, Mette & Holst, Jens Juul, 2017, In: Nutrients. 9, 4, 15 p., 418.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The Effect of Smallpox and Bacillus Calmette-Guérin Vaccination on the Risk of Human Immunodeficiency Virus-1 Infection in Guinea-Bissau and Denmark

    Rieckmann, Andreas, Villumsen, M., Jensen, M. L., Ravn, H., da Silva, Z. J., Sørup, S., Baker, J. L., Rodrigues, A., Benn, C. S., Roth, A. E. & Aaby, P., 2017, In: Open Forum Infectious Diseases. 4, 3, 10 p., ofx130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The Genetic Landscape of Renal Complications in Type 1 Diabetes

    Sandholm, N., Van Zuydam, N., Ahlqvist, E., Juliusdottir, T., Deshmukh, H. A., Rayner, N. W., Di Camillo, B., Forsblom, C., Fadista, J., Ziemek, D., Salem, R. M., Hiraki, L. T., Pezzolesi, M., Trégouët, D., Dahlström, E., Valo, E., Oskolkov, N., Ladenvall, C., Marcovecchio, M. L., Cooper, J. & 32 others, Sambo, F., Malovini, A., Manfrini, M., McKnight, A. J., Lajer, M., Harjutsalo, V., Gordin, D., Parkkonen, M., FinnDiane Study Group, F. S. G., Tuomilehto, J., Lyssenko, V., McKeigue, P. M., Rich, S. S., Brosnan, M. J., Fauman, E., Bellazzi, R., Rossing, Peter, Hadjadj, S., Krolewski, A., Paterson, A. D., The DCCT/EDIC Study Group, T. D. S. G., Florez, J. C., Hirschhorn, J. N., Maxwell, A. P., GENIE Consortium, G. C., Dunger, D., Cobelli, C., Colhoun, H. M., Groop, L., McCarthy, M. I., Groop, P. & on behalf of The SUMMIT Consortium, O. B. O. T. S. C., 2017, In: Journal of the American Society of Nephrology. 28, 2, p. 557-574

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The Microbiota and Epigenetic Regulation of T Helper 17/Regulatory T Cells: In Search of a Balanced Immune System

    Luo, A., Leach, S. T., Barrès, Romain, Hesson, L. B., Grimm, M. C. & Simar, D., 2017, In: Frontiers in Immunology. 8, 14 p., 417.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    The angiotensin type 2 receptor and the kidney

    Peluso, A. A. B., Santos, R. A. S., Unger, T. & Steckelings, U. M., 2017, In: Current Opinion in Nephrology and Hypertension.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The effect of metformin on a healthy human gut microbiota

    Nielsen, T., Bryrup, T., Thomsen, C. W., Hansen, T. H., Kern, T., Allin, K. H., Jørgensen, N. R., drb459, drb459, Hansen, T. & Pedersen, Oluf Borbye, 2017, In: Diabetologia. 60, Suppl. 1, p. S113 1 p., 241.

    Research output: Contribution to journal › Conference abstract in journal › Research

  17. Published

    The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes

    Sørensen, A., Kjær, L. K., Petersen, K. M., Henriksen, T., Cejvanovic, V., Pedersen, Oluf Borbye, Hansen, Torben, Christensen, C. K., Brandslund, I. & Poulsen, Henrik Enghusen, 2017, In: Scandinavian Journal of Clinical & Laboratory Investigation. 77, 4, p. 253-258 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The identification and functional annotation of RNA structures conserved in vertebrates

    Seemann, Ernst Stefan, Mirza, A. H., Hansen, C., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Torarinsson, E., Yao, Z., Workman, C. T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Genome Research. 27, p. 1371-1383 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

    Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The influence of persistent organic pollutants in the traditional Inuit diet on markers of inflammation

    Schæbel, L. K., Bonefeld-Jørgensen, E. C., drb459, drb459 & Andersen, S., 2017, In: PLOS ONE. 12, 5, 16 p., e0177781.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB

    pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts

    Friedrich, N., Pietzner, M., Cannet, C., Thuesen, B. H., Hansen, Torben, Wallaschofski, H., Grarup, N., Skaaby, T., Budde, K., Pedersen, Oluf Borbye, Nauck, M. & Linneberg, Allan René, 2017, In: PLOS ONE. 12, 3, 17 p., e0173078.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass

    Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Variations in the prevalence of obesity among european countries, and a consideration of possible causes

    Blundell, J. E., Baker, J. L., Boyland, E., Blaak, E., Charzewska, J., De Henauw, S., Frühbeck, G., Gonzalez-Gross, M., Hebebrand, J., Holm, Lotte, Kriaucioniene, V., Lissner, L., Oppert, J. M., Schindler, K., Silva, A. M. & Woodward, E., 2017, In: Obesity Facts. 10, p. 25-37 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Linneberg, Allan René, Sørensen, Thorkild I.A., Ängquist, Lars & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2017, In: The Lancet. 389, 10064, p. 37-55 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

    Bentham, J., Di Cesare, M., Bilano, V., Jørgensen, T., Linneberg, Allan René, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Osler, Merete, Sørensen, Thorkild I.A., Zhussupov, B., Zimmermann, E., Cisneros, J. Z., Damsgaard, Camilla Trab, Ängquist, Lars & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2017, In: Lancet. 390, 10113, p. 2627-2642 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2016
  28. Published

    Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)

    Karlshøj, S., Amarandi, R. M., Larsen, Olav, Daugvilaite, V., Steen, A., Brvar, M., Pui, A., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 23 Dec 2016, In: Journal of Biological Chemistry. 291, 52, p. 26860-26874

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia

    Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, Steen Seier, Spengler, B., Janfelt, Christian & Hansen, Harald S., 22 Dec 2016, In: Scientific Reports. 6, p. 1-14 14 p., 39571.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Proteomics reveals the effects of sustained weight loss on the human plasma proteome

    Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The Human Intestinal Microbiome in Health and Disease

    Lynch, S. V. & Pedersen, Oluf Borbye, 15 Dec 2016, In: New England Journal of Medicine. 375, 24, p. 2369-2379 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    The role of kisspeptin and RFRP in the circadian control of female reproduction

    Beymer, M., Henningsen, J., Bahougne, T. & Simonneaux, V., 15 Dec 2016, In: Molecular and Cellular Endocrinology. 438, p. 89-99 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994

    Jelenkovic, A., Hur, Y-M., Sund, R., Yokoyama, Y., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q., Zhang, D., Pang, Z., Aaltonen, S., Heikkila, K., Oncel, S. Y., Aliev, F., Rebato, E., Tarnoki, A. D., Tarnoki, D. L., Christensen, K., Skytthe, A. & 79 others, Kyvik, K. O., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Ordonana, J. R., Sanchez-Romera, J. F., Colodro-Conde, L., Cozen, W., Hwang, A. E., Mack, T. M., Sun, J., Song, Y., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl-Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Lichtenstein, P., Spector, T. D., Mangino, M., Lachance, G., Bartels, M., van Beijsterveldt, T. C. E. M., Willemsen, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Hjelmborg, J. V. B., Goldberg, J. H., Iwatani, Y., Watanabe, M., Honda, C., Inui, F., Rasmussen, F., Huibregtse, B. M., Boomsma, D. I., Sørensen, Thorkild I.A., Kaprio, J. & Silventoinen, K., 14 Dec 2016, In: eLife. 5, p. 1-14 14 p., e20320.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

    Mahmood, B., Damm, M. M. B., Jensen, T. S. R., Backe, M. B., Dahllöf, M. S., Poulsen, Steen Seier, Bindslev, Niels & Hansen, M. B., 7 Dec 2016, In: B M C Cancer. 16, 12 p., 938.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    (1)H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity

    Nissen, A., Fonvig, C. E., Chabanova, E., Bøjsøe, C., Trier, C., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, Dec 2016, In: Obesity Science & Practice. 2, 4, p. 376-384 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

    Southey, M. C., Goldgar, D. E., Winqvist, R., Pylkäs, K., Couch, F., Tischkowitz, M., Foulkes, W. D., Dennis, J., Michailidou, K., van Rensburg, E. J., Heikkinen, T., Nevanlinna, H., Hopper, J. L., Dörk, T., Claes, K. B., Reis-Filho, J., Teo, Z. L., Radice, P., Catucci, I., Peterlongo, P. & 31 others, Tsimiklis, H., Odefrey, F. A., Dowty, J. G., Schmidt, M. K., Broeks, A., Hogervorst, F. B., Verhoef, S., Carpenter, J., Clarke, C., Scott, R. J., Fasching, P. A., Haeberle, L., Ekici, A. B., Beckmann, M. W., Peto, J., Dos-Santos-Silva, I., Fletcher, O., Johnson, N., Bolla, M. K., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Marme, F., Bojesen, Stig Egil, Nordestgaard, Børge, Kjær, Susanne Krüger, Høgdall, Estrid Vilma Solyom, Høgdall, Claus Kim, Engelholm, S. A. & Australian Ovarian Cancer Study Group, A. O. C. S. G., Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 800-811

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Depressive symptoms in women's midlife in relation to their body weight before, during and after childbearing years

    Bliddal, M., Pottegård, A., Kirkegaard, H., Olsen, J., Sørensen, Thorkild I.A. & Nohr, E. A., Dec 2016, In: Obesity Science & Practice. 2, 4, p. 415-425 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females

    Junnila, R. K., Duran-Ortiz, S., Suer, O., Sustarsic, E. G., Berryman, D. E., List, E. O. & Kopchick, J. J., Dec 2016, In: Endocrinology. 157, 12, p. 4502-4513

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Excessive gains in BMI during adolescence increase risks of cardiovascular mortality in men

    Baker, J. L., Dec 2016, In: The Lancet Diabetes & Endocrinology. 4, 12, p. 964-966 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  40. Published

    Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Barban, N., Jansen, R., de Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., van der Laan, S. W., Perry, J. R. B., Kong, A., Ahluwalia, T. V. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., Ayers, K. & 31 others, Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Bisgaard, H., Bønnelykke, Klaus, Waage, J. & BIOS Consortium, B. C., Dec 2016, In: Nature Genetics. 48, 12, p. 1462-1472 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Impact of body composition changes on risk of all-cause mortality in older adults

    Graf, C. E., Herrmann, F. R., Spoerri, A., Makhlouf, A., Sørensen, Thorkild I.A., Ho, S., Karsegard, V. L. & Genton, L., Dec 2016, In: Clinical Nutrition. 35, 6, p. 1499-1505 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years

    Justesen, Johanne Marie, Andersson, E. A., Allin, K. H., Sandholt, C. H., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye & Grarup, N., Dec 2016, In: Journal of Lipid Research. 57, 12, p. 2193-2199 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels

    pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

    Ried, J. S., Jeff M, J., Chu, A. Y., Bragg-Gresham, J. L., van Dongen, J., Huffman, J. E., Ahluwalia, T. V. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S., Kristiansson, K. & 256 others, Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Stančáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., van der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D'Avila, F., de Geus, E. J. C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. M. P., Glorioso, N., Graff, M., Grallert, H., Grarup, N., Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Justesen, Johanne Marie, Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-Kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, Allan René, Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., McArdle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-Madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., van der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-Armstrong, L. M., Hua Zhao, J., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, Torben, Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, Oluf Borbye, Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, Peter, Shudiner, A. R., Smit, J. H., Sørensen, Thorkild I.A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., McCarthy, M. I., North, K. E., O'Connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., 23 Nov 2016, In: Nature Communications. 7, 11 p., 13357.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Building Bridges through Scientific Conferences

    Zierath, Juleen R, 17 Nov 2016, In: Cell. 167, 5, p. 1155-1158 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  46. Published

    Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology

    Schnurr, T. M., Gjesing, A. M. P., Sandholt, C. H., Jonsson, Anna Elisabet, Mahendran, Y., Have, C. T., Ekstrøm, Claus Thorn, Bjerregaard, A., Brage, S., Witte, D., Jørgensen, M. E., Aadahl, Mette, Thuesen, B. H., Linneberg, Allan René, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Grarup, N., Kilpeläinen, Tuomas O. & Hansen, Torben, 15 Nov 2016, In: P L o S One. 11, 11, 14 p., e0166738.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs

    Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  48. Published

    15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

    Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J. & 7 others, Karjalainen-Lindsberg, M., Workman, C. T., Garde, C., Elonen, E., Brown, Peter de Nully, Grønbæk, Kirsten & Geisler, C. H., Nov 2016, In: British Journal of Haematology. 175, 3, p. 410-418 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Airway irritation, inflammation, and toxicity in mice following inhalation of metal oxide nanoparticles

    Larsen, S. T., Jackson, P., Poulsen, Steen Seier, Levin, M., Jensen, K. A., Wallin, H., Nielsen, G. D. & Koponen, I. K., Nov 2016, In: Nanotoxicology. 10, 9, p. 1254-1262 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Associations between childhood height and morphologically different variants of melanoma in adulthood

    Meyle, K. D., Gamborg, M. O., Hølmich, Lisbet Rosenkrantz & Baker, J. L., Nov 2016, In: European journal of cancer (Oxford, England : 1990). 67, p. 99-105 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Disturbed postprandial glucose metabolism and gut hormone responses in non-diabetic patients with psoriasis

    Gyldenløve, M., Vilsbøll, Tina, Holst, Jens Juul, Zachariae, Claus, Skov, L. & Knop, Filip Krag, Nov 2016, In: British Journal of Dermatology. 175, 5, p. 1085–1088

    Research output: Contribution to journal › Letter › Research › peer-review

  52. Published

    Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment

    Baranov, O., Kahle, M., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Nov 2016, In: Diabetes, Obesity and Metabolism. 18, 11, p. 1100-1109 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Higher Endogenous Glucose Production during OGTT vs Isoglycemic Intravenous Glucose Infusion

    Lund, Asger Bach, Bagger, J. I., Christensen, Mikkel Bring, Grøndahl, M., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 11, p. 4377-4384

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Lipoprotein (a) as a cause of cardiovascular disease: insights from epidemiology, genetics, and biology

    Nordestgaard, Børge & Langsted, A., Nov 2016, In: Journal of Lipid Research. 57, 11, p. 1953-1975 23 p.

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial

    Gæde, P., Øllgaard, J. C., Carstensen, Bendix, Rossing, Peter, Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, Nov 2016, In: Diabetologia. 59, 11, p. 2298-2307 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Svær overvægt hos børn og unge

    Kloppenborg, J. T. & Holm, Jens-Christian, 31 Oct 2016, In: Ugeskrift for Laeger. 178, 22, p. 2089-2092 4 p., V06160432.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

    Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Vejle diabetes Biobank: A resource for studies of the etiologies of diabetes and its comorbidities

    Petersen, E. R. B., Nielsen, A. A., Christensen, H., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K. & Brandslund, I., 21 Oct 2016, In: Clinical Epidemiology. 8, p. 393-413 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Improved pan-specific prediction of MHC class I peptide binding using a novel receptor clustering data partitioning strategy

    Mattsson, A. H., Kringelum, J. V., Garde, C. & Nielsen, M., 20 Oct 2016, In: HLA. 88, 6, p. 287-292 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Resolution of non-alcoholic steatohepatitis after growth hormone replacement in a pediatric liver transplant patient with panhypopituitarism

    Gilliland, T., Dufour, S., Shulman, G. I., Petersen, K. F. & Emre, S. H., 20 Oct 2016, In: Pediatric Transplantation. 20, 8, p. 1157-1163 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

    van der Beek, C. M., Canfora, E. E., Lenaerts, K., Troost, F. J., Damink, S. W. M. O., Holst, Jens Juul, Masclee, A. A. M., Dejong, C. H. C. & Blaak, E. E., 11 Oct 2016, In: Clinical Science. 130, 22, p. 2073-2082 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

    Ratajczak, J., Joffraud, M., Trammell, Sam, Ras, R., Canela, N., Boutant, M., Kulkarni, S. S., Rodrigues, M., Redpath, P., Migaud, M. E., Auwerx, J., Yanes, O., Brenner, C. & Cantó, C., 11 Oct 2016, In: Nature Communications. 7, 13103.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11)

    Navia-Paldanius, D., Patel, J. Z., López Navarro, M., Jakupovic, Hermina, Goffart, S., Pasonen-Seppänen, S., Nevalainen, T. J., Jääskeläinen, T., Laitinen, T., Laitinen, J. T. & Savinainen, J. R., 10 Oct 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 253-263 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

    Trammell, Sam, Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., Li, Z., Abel, E. D., Migaud, M. E. & Brenner, C., 10 Oct 2016, In: Nature Communications. 7, 12948.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Signals from the gut microbiota to distant organs in physiology and disease

    Schroeder, B. O. & Bäckhed, G. F., 6 Oct 2016, In: Nature Medicine. 22, 10, p. 1079-1089 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium

    Muranen, T. A., Blomqvist, C., Dörk, T., Jakubowska, A., Heikkilä, P., Fagerholm, R., Greco, D., Aittomäki, K., Bojesen, S. E., Shah, M., Dunning, A. M., Rhenius, V., Hall, P., Czene, K., Brand, J. S., Darabi, H., Chang-Claude, J., Rudolph, A., Nordestgaard, B. G., Couch, F. J. & 24 others, Hart, S. N., Figueroa, J., García-Closas, M., Fasching, P. A., Beckmann, M. W., Li, J., Liu, J., Andrulis, I. L., Winqvist, R., Pylkäs, K., Mannermaa, A., Kataja, V., Lindblom, A., Margolin, S., Lubinski, J., Dubrowinskaja, N., Bolla, M. K., Dennis, J., Michailidou, K., Wang, Q., Easton, D. F., Pharoah, P. D. P., Schmidt, M. K. & Nevanlinna, H., 3 Oct 2016, In: Breast Cancer Research (Online). 18, 15 p., 98.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

    Bonilla, C., Lewis, S. J., Rowlands, M-A., Gaunt, T. R., Davey-Smith, G., Gunnell, D., Palmer, T. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G., Wiklund, F., Grönberg, H., Haiman, C. A. & 22 others, Schleutker, J., Nordestgaard, Børge, Travis, R. C., Pashayan, N., Khaw, K., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., PRACTICAL consortium, P. C., Lathrop, M., Martin, R. M. & Holly, J. M. P., 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1520-1533 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Gene set analysis for interpreting genetic studies

    Pers, Tune H, 1 Oct 2016, In: Human Molecular Genetics. 25, R2, p. R133-R140 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  69. Published

    Inflammatory biomarkers and risk of cancer in 84,000 individuals from the general population

    Allin, K. H., Bojesen, Stig Egil & Nordestgaard, Børge, 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1493-500 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci

    Walford, G. A., Gustafsson, S., Rybin, D., Stančáková, A., Chen, H., Liu, C-T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 others, Montasser, M. E., Landenvall, C., Staiger, H., Luan, J., Frayling, T. M., Weedon, M. N., Xie, W., Morcillo, S., Martínez-Larrad, M. T., Biggs, M. L., Ida Chen, Y., Corbaton-Anchuelo, A., Faerch, K., Zumaquero, J. M., Goodarzi, M. O., Kizer, J., Koistinen, H. A., Leong, A., Lind, L., Lindgren, C., Machicao, F., Manning, A. K., Martín-Núñez, G. M., Rojo-Martínez, G., Rotter, J. I., Siscovick, D. S., Zmuda, J. M., Zhang, Z., Serrano-Rios, M., Smith, U., Soriguer, F., Hansen, Torben, Jørgensen, T., Linnenberg, A., Pedersen, Oluf Borbye, Walker, M., Langenberg, C., Scott, R. A., Wareham, N. J., Fritsche, A., Häring, H., Stefan, N., Groop, L., O'Connell, J. R., Boehnke, M., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., März, W., Kovacs, P., Stumvoll, M., Psaty, B. M., Kuusisto, J., Laakso, M., Meigs, J. B., Dupuis, J., Ingelsson, E. & Florez, J. C., Oct 2016, In: Diabetes. 65, 10, p. 3200-3211 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    High body mass index and risk of exacerbations and pneumonias in individuals with chronic obstructive pulmonary disease: observational and genetic risk estimates from the Copenhagen General Population Study

    Çolak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, Oct 2016, In: International Journal of Epidemiology. 45, 5, p. 1551-1559 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    In vivo characterization of the ultrapotent monoacylglycerol lipase inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048)

    Aaltonen, N., Kedzierska, E., Orzelska-Górka, J., Lehtonen, M., Navia-Paldanius, D., Jakupovic, Hermina, Savinainen, J. R., Nevalainen, T., Laitinen, J. T., Parkkari, T. & Gynther, M., Oct 2016, In: Journal of Pharmacology and Experimental Therapeutics. 359, 1, p. 62-72 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Involvement of glucagon-like peptide-1 in the glucose-lowering effect of metformin

    Bahne, E., Hansen, M., Brønden, A., Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, Oct 2016, In: Diabetes, Obesity and Metabolism Online. 18, 10, p. 955-61 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  74. Published

    Long telomeres and cancer risk among 95 568 individuals from the general population

    Rode, L., Nordestgaard, Børge & Bojesen, Stig Egil, Oct 2016, In: International Journal of Epidemiology. 45, 5, p. 1634-1643 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

    Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A. D., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D. W., Mowry, B. J., Müller-Mhysok, B., Neale, B. M. & 297 others, Nenadic, I., Nöthen, M. M., O’Dushlaine, C., Rietschel, M., Ruderfer, D. M., Rujescu, D., Schulze, T. G., Simonson, M. A., Stahl, E. A., Strohmaier, J., Witt, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K., Holmans, P. A., Lee, P. H., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, Tune H, Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W. F., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Robert Cloninger, C., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Del-Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., de Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julià, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Chee Keong, J. L., Hong Lee, S., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Mallet, J., Marsal, S., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S. M., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C. T., Anthony O'Neill, F., Oh, S. Y., Olincy, A., Olsen, L., van Os, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A. L., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, Henrik Berg, Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Watts-Williams, S. J., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Riley, B. P., Sham, P., Sklar, P., St Clair, D., Weinberger, D. R., Wendland, J. R., Werge, Thomas, Daly, M. J., O'Donovan, M. C., Sullivan, P. F. & Keller, M. C., Oct 2016, In: PLOS Genetics. 12, 10, 20 p., e1006343.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.

    Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro

    Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Reproducibility of coronary atherosclerotic plaque characteristics in populations with low, intermediate, and high prevalence of coronary artery disease by multidetector computer tomography: a guide to reliable visual coronary plaque assessments

    de Knegt, M. C., Linde, J. J., Fuchs, A., Nordestgaard, Børge, Køber, Lars Valeur, Hove, Jens Dahlgaard & Kofoed, Klaus Fuglsang, Oct 2016, In: International Journal of Cardiovascular Imaging. 32, 10, p. 1555-66 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    The U-shaped association of body mass index with mortality: Influence of the traits height, intelligence, and education

    Jørgensen, Terese Sara Høj, Osler, Merete, Ängquist, Lars, Zimmermann, E., Okholm, Gunhild Tidemann & Sørensen, Thorkild I.A., Oct 2016, In: Obesity. 24, 10, p. 2240–2247 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    The gut microbiota and metabolic disease: current understanding and future perspectives

    Arora, T. & Bäckhed, G. F., Oct 2016, In: Journal of Internal Medicine. 280, 4, p. 339-49 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  81. Published

    Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

    Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, Jens Juul, Reimann, F. & Gribble, F. M., Oct 2016, In: Diabetologia. 59, 10, p. 2156-2165 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Genome-wide associations for birth weight and correlations with adult disease

    Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., Feenstra, B., van Zuydam, N. R., Gaulton, K. J., Grarup, N., Bradfield, J. P., Strachan, D. P., Li-Gao, R., Ahluwalia, T. V. S., Kreiner, E., Rueedi, R., Lyytikäinen, L-P., Cousminer, D. L., Wu, Y., Thiering, E. & 31 others, Wang, C. A., Have, C. T., Hottenga, J., Vilor-Tejedor, N., Joshi, P. K., Boh, E. T. H., Ntalla, I., Pitkänen, N., Mahajan, A., van Leeuwen, E. M., Joro, R., Lagou, V., Nodzenski, M., Diver, L. A., Zondervan, K. T., Bustamante, M., Marques-Vidal, P., Mercader, J. M., Appel, E. V. R., Waage, J., Sørensen, Thorkild I.A., Melbye, M., Kadarmideen, H. N., Holm, Jens-Christian, Hansen, Torben, Bønnelykke, Klaus, Bisgaard, H., Pisinger, C., Pedersen, Oluf Borbye, Vaag, Allan & CHARGE Consortium Hematology Working Group, C. C. H. W. G., 28 Sep 2016, In: Nature. 538, p. 248-252 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  83. Published

    52 Genetic Loci Influencing Myocardial Mass

    van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L-P., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M. & 140 others, Smith, A. V., Dörr, M., Kerr, K. F., Magnani, J. W., Del Greco M, F., Zhang, W., Nolte, I. M., Silva, C. T., Padmanabhan, S., Tragante, V., Esko, T., Abecasis, G. R., Adriaens, M. E., Andersen, K., Barnett, P., Bis, J. C., Bodmer, R., Buckley, B. M., Campbell, H., Cannon, M. V., Chakravarti, A., Chen, L. Y., Delitala, A., Devereux, R. B., Doevendans, P. A., Dominiczak, A. F., Ferrucci, L., Ford, I., Gieger, C., Harris, T. B., Haugen, E., Heinig, M., Hernandez, D. G., Hillege, H. L., Hirschhorn, J. N., Hofman, A., Hubner, N., Hwang, S., Iorio, A., Kähönen, M., Kellis, M., Kolcic, I., Kooner, I. K., Kooner, J. S., Kors, J. A., Lakatta, E. G., Lage, K., Launer, L. J., Levy, D., Lundby, Alicia, Macfarlane, P. W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A. S., Nutile, T., Okin, P. M., Olsen, Jesper Velgaard, Oostra, B. A., Penninger, J. M., Pennacchio, L. A., Pers, Tune H, Perz, S., Peters, A., Pinto, Y. M., Pfeufer, A., Pilia, M. G., Pramstaller, P. P., Prins, B. P., Raitakari, O. T., Raychaudhuri, S., Rice, K. M., Rossin, E. J., Rotter, J. I., Schafer, S., Schlessinger, D., Schmidt, C. O., Sehmi, J., Silljé, H. H. W., Sinagra, G., Sinner, M. F., Slowikowski, K., Soliman, E. Z., Spector, T. D., Spiering, W., Stamatoyannopoulos, J. A., Stolk, R. P., Strauch, K., Tan, S., Tarasov, K. V., Trinh, B., Uitterlinden, A. G., van den Boogaard, M., van Duijn, C. M., van Gilst, W. H., Viikari, J. S., Visscher, P. M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C. X., Westra, H., Wijmenga, C., Wolffenbuttel, B. H., Yang, J., Bezzina, C. R., Munroe, P. B., Snieder, H., Wright, A. F., Rudan, I., Boyer, L. A., Asselbergs, F. W., van Veldhuisen, D. J., Stricker, B. H., Psaty, B. M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J. F., Bandinelli, S., Alonso, A., Gasparini, P., Jukema, J. W., Kääb, S., Gudnason, V., Felix, S. B., Heckbert, S. R., de Boer, R. A., Newton-Cheh, C., Hicks, A. A., Chambers, J. C., Jamshidi, Y., Visel, A., Christoffels, V. M., Isaacs, A., Samani, N. J. & de Bakker, P. I. W., 27 Sep 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Growth in Total Height and Its Components and Cardiometabolic Health in Childhood

    Haugaard, L. K., Baker, J. L., Perng, W., Belfort, M. B., Rifas-Shiman, S. L., Switkowski, K., Oken, E. & Gillman, M. W., 23 Sep 2016, In: PLOS ONE. 11, 9, p. 1-15 15 p., e0163564.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Ionizing Radiation Potentiates High Fat Diet-Induced Insulin Resistance and Reprograms Skeletal Muscle and Adipose Progenitor Cells

    Nylander, V., Ingerslev, L. R., Andersen, E., Fabre, O., Garde, C., Rasmussen, M., Citirikkaya, K., Bæk, J., Christensen, G. L., Aznar, M., Specht, Lena, Simar, D. & Barrès, Romain, 20 Sep 2016, In: Diabetes. 65, 12, p. 3573-3584 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Epigenetisk påvirkning af fosterets udvikling

    Donkin, I., Barrès, Romain & Pinborg, Anja, 12 Sep 2016, In: Ugeskrift for Laeger. 178, 37, p. 2-5 V02160132.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., Shah, S. & 31 others, Kleber, M. E., Guo, X., Lyytikäinen, L., Fava, C., Eriksson, N., Nolte, I. M., Magnusson, P. K., Salfati, E. L., Rallidis, L. S., Theusch, E., Smith, A. J. P., Folkersen, L., Witkowska, K., Pers, Tune H, Joehanes, R., Kim, S. K., Lataniotis, L., Jansen, R., Johnson, A. D., Warren, H., Kim, Y. J., Zhao, W., Wu, Y., Tayo, B. O., Bochud, M., Absher, D., Adair, L. S., Amin, N., Njølstad, I., Schwarz, Peter & CHARGE-EchoGen Consortium, C. C., 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1171-1184 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 32 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Havulinna, A. S., Husemoen, L. L., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye, Nordestgaard, Børge, CHARGE-Heart Failure Consortium, C. F. C. & V Varga, Tibor, 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1151-1161 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    The biology of glucagon and the consequences of hyperglucagonemia

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Pedersen, Jens, Knop, Filip Krag & Holst, Jens Juul, 9 Sep 2016, In: Biomarkers in Medicine. 10, 11, p. 1141-1151 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Ethnic inequalities in overweight and obesity prevalence among copenhagen schoolchildren from 2002 to 2007

    Pedersen, D. C., Aarestrup, J., Pearson, S. & Baker, J. L., 1 Sep 2016, In: Obesity Facts. 9, 4, p. 284-295 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Guidelines: Surgical or medical therapy for patients with obesity and T2DM?

    Madsbad, Sten & Holst, Jens Juul, 1 Sep 2016, In: Nature Reviews Endocrinology. 12, 9, p. 500-502 3 p.

    Research output: Contribution to journal › Comment/debate › Communication

  92. Published

    Alcohol consumption and risk of atrial fibrillation: Observational and genetic estimates of association

    Tolstrup, J. S., Wium-Andersen, M. K., Ørsted, D. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Preventive Cardiology. 23, 14, p. 1514-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    BODY MASS INDEX AND MORTALITY OVER 3 DECADES

    Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, Sep 2016, In: Atherosclerosis. 252, p. E222-E222 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  94. Published

    Diabetes and obesity treatment based on dual incretin receptor activation: ‘twincretins’

    Skow, M. A., Bergmann, N. C. & Knop, Filip Krag, Sep 2016, In: Diabetes, Obesity and Metabolism. 18, 9, p. 847-54 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  95. Published

    Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery

    Ratner, C., Skov, Louise Julie, Raida, Z., Bächler, T., Bellmann-Sickert, K., Le Foll, C., Sivertsen, B., Dalbøge, L. S., Hartmann, Bolette, Beck-Sickinger, A. G., Madsen, A. N., Jelsing, J., Holst, Jens Juul, Lutz, T. A., Andrews, Z. B. & Holst, Birgitte, Sep 2016, In: Endocrinology. 157, 9, p. 3482-92 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

    Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, N., Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

    Kar, S. P., Beesley, J., Amin Al Olama, A., Michailidou, K., Tyrer, J., Kote-Jarai, ZS., Lawrenson, K., Lindstrom, S., Ramus, S. J., Thompson, D. J., Kibel, A. S., Dansonka-Mieszkowska, A., Michael, A., Dieffenbach, A. K., Gentry-Maharaj, A., Whittemore, A. S., Wolk, A., Monteiro, A., Peixoto, A., Kierzek, A. & 31 others, Cox, A., Rudolph, A., Gonzalez-Neira, A., Wu, A. H., Lindblom, A., Swerdlow, A., Ziogas, A., Ekici, A. B., Burwinkel, B., Karlan, B. Y., Nordestgaard, Børge, Blomqvist, C., Phelan, C., McLean, C., Pearce, C. L., Vachon, C., Cybulski, C., Slavov, C., Stegmaier, C., Maier, C., Ambrosone, C. B., Høgdall, Claus Kim, Teerlink, C. C., Kang, D., Tessier, D. C., Schaid, D. J., Stram, D. O., Høgdall, Estrid Vilma Solyom, Bojesen, Stig Egil, Kjær, Susanne Krüger & ABCTB Investigators, A. I., Sep 2016, In: Cancer Discovery. 6, 9, p. 1052-67 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Limited availability of childhood overweightand obesity treatment programmes in Danish paediatric departments

    Eg, M., Cortes, Dina, Johansen, A., Frederiksen, K., Lorentzen, V., Larsen, L. M., Holm, Jens-Christian & Vámosi, M., Sep 2016, In: Danish Medical Journal. 63, 9, p. 1-5 5 p., A5269.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Lipoprotein Apheresis for Lipoprotein(a)-Associated Cardiovascular Disease: Prospective 5 Years of Follow-Up and Apolipoprotein(a) Characterization

    Roeseler, E., Julius, U., Heigl, F., Spitthoever, R., Heutling, D., Breitenberger, P., Leebmann, J., Lehmacher, W., Kamstrup, P. R., Nordestgaard, Børge, Maerz, W., Noureen, A., Schmidt, K., Kronenberg, F., Heibges, A., Klingel, R. & Pro(a)LiFe-Study Group, P. G., Sep 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 2019-2027 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Microbial regulation of GLP-1 and L-cell biology

    Greiner, T. U. & Bäckhed, G. F., Sep 2016, In: Molecular Metabolism. 5, 9, p. 753-8 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  101. Published

    No Islet Cell Hyperfunction, but Altered Gut-Islet Regulation and Postprandial Hypoglycemia in Glucose-Tolerant Patients 3 Years After Gastric Bypass Surgery

    Dirksen, C., Eiken, A., Bojsen-Møller, K. N., Svane, M. S., Martinussen, C., Jørgensen, N. B., Holst, Jens Juul & Madsbad, Sten, Sep 2016, In: Obesity Surgery. 26, 9, p. 2263-7 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  102. Published

    Opposite Regulation of Ghrelin and Glucagon-like Peptide-1 by Metabolite G-Protein-Coupled Receptors

    Engelstoft, M. S. & Schwartz, Thue W., Sep 2016, In: Trends in Endocrinology and Metabolism. 27, 9, p. 665-675 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

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