Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2016
  2. Published

    Pregnancy and childhood exposure to residential traffic noise and overweight at 7 years of age

    Christensen, J. S., Hjortebjerg, D., Raaschou-Nielsen, O., Ketzel, M., Sørensen, Thorkild I.A. & Sørensen, M., Sep 2016, In: Environment International. 94, 9, p. 170-176 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Response to 'Prenatal exposure to vitamin-D from fortified margarine and milk and body size at age 7 years'

    Jensen, C. B., Stougård, M., Sørensen, Thorkild I.A. & Heitmann, Berit, Sep 2016, In: European Journal of Clinical Nutrition. 70, 9, p. 1092 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  4. Published

    The metabolic actions of neurotensin secreted from the gut

    Ratner, C., Johnsen, Cecilie Hundahl & Holst, Birgitte, Sep 2016, In: Cardiovascular Endocrinology. 5, 3, p. 102-111

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Tracking of body mass index from 7 to 69 years of age

    Aarestrup, J., Bjerregaard, L. G., Gamborg, Michael Orland, Ängquist, Lars, Tjønneland, Anne, Overvad, K., Linneberg, Allan René, Osler, Merete, Mortensen, Erik Lykke, Gyntelberg, F., Lund, Rikke, Sørensen, Thorkild I.A. & Baker, J. L., Sep 2016, In: International Journal of Obesity. 40, 9, p. 1376-1383 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells

    Schmidt, S. F., Madsen, J. G. S., Frafjord, K. Ø., Poulsen, L. L. C., Salö, S., Boergesen, M., Loft, A., Larsen, B. D., Madsen, M. S., Holst, Jens Juul, Maechler, P., Dalgaard, L. T. & Mandrup, S., 30 Aug 2016, In: Cell Reports. 16, 9, p. 2359-72 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

    Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Albrechtsen, Nicolai Jacob Wewer, Rehfeld, Jens Frederik, Hartmann, Bolette, Madsbad, Sten & Holst, Jens Juul, 30 Aug 2016, In: International Journal of Obesity. 40, p. 1699–1706

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119

    Hassing, H. A., Fares, S., Larsen, Olav, Pad, H., Pedersen, M. H., Jones, R. M., Schwartz, Thue W., Hansen, Harald S. & Rosenkilde, Mette, 26 Aug 2016, In: Biochemical Pharmacology. 119, 1, p. 66-75 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Transcriptional interactions suggest niche segregation among microorganisms in the human gut

    Plichta, D. R., Juncker, A. S., Bertalan, M., Rettedal, E., Gautier, L., Varela, E., Manichanh, C., Fouqueray, C., Levenez, F., Nielsen, T., Doré, J., Machado, A. M. D., de Evgrafov, M. C. R., Hansen, T., Jørgensen, T., Bork, P., Guarner, F., Pedersen, O., Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium, Sommer, M. O. A. & 4 others, Ehrlich, S. D., Sicheritz-Pontén, T., Brunak, Søren & Nielsen, H. B., 26 Aug 2016, In: Nature Microbiology. 1, p. 1-6 6 p., 16152.

    Research output: Contribution to journal › Letter › Research › peer-review

  10. Published

    Stress hormone release is a key component of the metabolic response to lipopolysaccharide (LPS): studies in hypopituitary and healthy subjects

    Bach, E., Møller, A. B., Jorgensen, J. O. L., Vendelbo, M. H., Jessen, N., Pedersen, S. B., Nielsen, Thomas Svava & Møller, N., 25 Aug 2016, In: European Journal of Endocrinology. 175, 5, p. 455-465 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Afferent Endocrine Control of Eating

    Langhans, W. & Holst, Jens Juul, 22 Aug 2016, Neuroendocrinology of Appetite. Dickson, S. L. & Mercer, J. G. (eds.). Wiley-Blackwell, p. 24-54 31 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  12. Published

    Antibiotic-mediated gut microbiome perturbation accelerates development of type 1 diabetes in mice

    Livanos, A. E., Greiner, T. U., Vangay, P., Pathmasiri, W., Stewart, D., McRitchie, S., Li, H., Chung, J., Sohn, J., Kim, S., Gao, Z., Barber, C., Kim, J., Ng, S., Rogers, A. B., Sumner, S., Zhang, X-S., Cadwell, K., Knights, D., Alekseyenko, A. & 2 others, Bäckhed, G. F. & Blaser, M. J., 22 Aug 2016, In: Nature Microbiology. 1, 11, p. 1-13 13 p., 16140.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

    Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium

    Khankari, N. K., Murff, H. J., Zeng, C., Wen, W., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, B. G., Travis, R. C., Donovan, J. L., Pashayan, N., Khaw, K-T. & 15 others, Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Zheng, W. & PRACTICAL consortium, P. C., 4 Aug 2016, In: B J C. 115, 5, p. 624-631 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The genetic architecture of type 2 diabetes

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B., Kim, Y., Kim, Y. J., Kwon, M., Lee, J., Lee, S., Lin, K., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stancáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, Johanne Marie, Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, Allan René, Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, Torben, Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, Oluf Borbye, Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Comparison of associations of maternal peri-pregnancy and paternal anthropometrics with child anthropometrics from birth through age 7 y assessed in the Danish National Birth Cohort

    Sørensen, Thorkild I.A., Ajslev, T. A., Ängquist, Lars, Morgen, C. S., Ciuchi, I. G. & Smith, G. D., 1 Aug 2016, In: The American Journal of Clinical Nutrition. 104, 2, p. 389-396 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents

    Perry, R. J., Cardone, R. L., Petersen, M. C., Zhang, D., Fouqueray, P., Hallakou-Bozec, S., Bolze, S., Shulman, G. I., Petersen, K. F. & Kibbey, R. G., 1 Aug 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E461-70

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Analysis of Case-Parent Trios Using a Loglinear Model with Adjustment for Transmission Ratio Distortion

    Huang, L. O., Infante-RIvard, C. & Labbe, A., Aug 2016, In: Frontiers in Genetics. 7, p. 1-10 10 p., 155.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study

    Silventoinen, K., Jelenkovic, A., Sund, R., Hur, Y-M., Yokoyama, Y., Honda, C., Hjelmborg, J. VB., Møller, S., Ooki, S., Aaltonen, S., Ji, F., Ning, F., Pang, Z., Rebato, E., Busjahn, A., Kandler, C., Saudino, K. J., Jang, K. L., Cozen, W., Hwang, A. E. & 84 others, Mack, T. M., Gao, W., Yu, C., Li, L., Corley, R. P., Huibregtse, B. M., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Heikkila, K., Wardle, J., Llewellyn, C. H., Fisher, A., McAdams, T. A., Eley, T. C., Gregory, A. M., He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Stazi, M. A., Fagnani, C., D'Ippolito, C., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Eaves, L. J., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Bartels, M., van Beijsterveldt, T. C. E. M., Craig, J. M., Saffery, R., Freitas, D. L., Maia, J. A., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Chong, Y., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Tynelius, P., Lichtenstein, P., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Oncel, S. Y., Aliev, F., Spector, T., Mangino, M., Lachance, G., Baker, L. A., Tuvblad, C., Duncan, G. E., Buchwald, D., Willemsen, G., Rasmussen, F., Goldberg, J. H., Sørensen, Thorkild I.A., Boomsma, D. I. & Kaprio, J., Aug 2016, In: The American Journal of Clinical Nutrition. 104, 2, p. 371-379

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Genetic risk scores link body fat distribution with specific cardiometabolic profiles

    Svendstrup, M., Sandholt, C. H., Andersson Galijatovic, E. A., Linneberg, Allan René, Jørgensen, T., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Grarup, N., Hansen, Torben & drb459, drb459, Aug 2016, In: Obesity. 24, 8, p. 1778-1785 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans

    Asmar, M., Simonsen, L., Asmar, Ali, Holst, Jens Juul, Dela, Flemming & Bülow, J., Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3155-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

    Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H. & 31 others, Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes & International Headache Genetics Consortium, I. H. G. C., Aug 2016, In: Nature Genetics. 48, 8, p. 856-66 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

    CHARGE Consortium Hematology Working Group, C. C. H. W. G., Aug 2016, In: Nature Genetics. 48, 8, p. 867-876 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice

    Arora, T., Wegmann, U., Bobhate, A., Lee, Y. S., Greiner, T. U., Drucker, D. J., Narbad, A. & Bäckhed, G. F., Aug 2016, In: Molecular Metabolism. 5, 8, p. 725-30 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Obstructive sleep apnea in obese children and adolescents, treatment methods and outcome of treatment: A systematic review

    Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, Aug 2016, In: International Journal of Pediatric Otorhinolaryngology. 87, p. 190-7 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Renin angiotensinogen system gene polymorphisms and essential hypertension among people of West African descent: a systematic review

    Reiter, L. M., Christensen, Dirk Lund & Gjesing, A. P., Aug 2016, In: Journal of Human Hypertension. 30, 8, p. 467–478 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    The role of diet and exercise in the transgenerational epigenetic landscape of T2DM

    Barrès, Romain & Zierath, Juleen R, Aug 2016, In: Nature Reviews Endocrinology. 12, 8, p. 441-51 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Total and Trimester-Specific Gestational Weight Gain and Offspring Birth and Early Childhood Weight: A Prospective Cohort Study on Monozygotic Twin Mothers and Their Offspring

    Scheers Andersson, E., Silventoinen, K., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., Aug 2016, In: Twin Research and Human Genetics. 19, 4, p. 367-76 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Towards leanness by 'feeding' a novel thermogenic pathway?

    Lund, Jens & Gillum, M. P., Aug 2016, In: Trends in Endocrinology and Metabolism. 27, 8, p. 529-530 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  30. Published

    A century of trends in adult human height

    Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 26 Jul 2016, In: eLife. 5, 29 p., e13410.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The Role of the Gut Microbiota in Childhood Obesity

    Pihl, A. F., Fonvig, C. E., Stjernholm, T., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 25 Jul 2016, In: Childhood Obesity. 12, 4, p. 292-299 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The Emerging Role of Epigenetics in Inflammation and Immunometabolism

    Raghuraman, S., Donkin, I., Versteyhe, S., Barrès, Romain & Simar, D., 18 Jul 2016, In: Trends in Endocrinology and Metabolism. 27, 11, p. 782-795 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Iron Regulation of Pancreatic Beta-Cell Functions and Oxidative Stress

    Backe, M. B., Moen, I. W., Ellervik, Christina, Hansen, J. B. & Mandrup-Poulsen, Thomas, 17 Jul 2016, In: Annual Review of Nutrition. 36, p. 241-273 33 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by (13)C Magnetic Resonance Spectroscopy

    Petersen, K. M. F., Befroy, D. E., Dufour, S., Rothman, D. L. & Shulman, G. I., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 167-71 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Digital questionnaire platform in the Danish Blood Donor Study

    Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial

    Reijnders, D., Goossens, G. H., Hermes, G. D. A., Neis, E. P. J. G., van der Beek, C. M., Most, J., Holst, Jens Juul, Lenaerts, K., Kootte, R. S., Nieuwdorp, M., Groen, A. K., Olde Damink, S. W. M., Boekschoten, M. V., Smidt, H., Zoetendal, E. G., Dejong, C. H. C. & Blaak, E. E., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 63-74 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

    Wahlström, A., Sayin, S. I., Marschall, H. & Bäckhed, G. F., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 41-50 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

    Mottillo, E. P., Desjardins, E. M., Crane, J. D., Smith, B. K., Green, A. E., Ducommun, S., Henriksen, T. I., Rebalka, I. A., Razi, A., Sakamoto, Kei, Schéele, Camilla Charlotte Nielsen, Kemp, B. E., Hawke, T. J., Ortega, J., Granneman, J. G. & Steinberg, G. R., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 118-129 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis

    De Vadder, F., Kovatcheva-Datchary, P., Zitoun, C., Duchampt, A., Bäckhed, G. F. & Mithieux, G., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 151-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Diet-microbiota interactions as moderators of human metabolism

    Sonnenburg, J. L. & Bäckhed, G. F., 7 Jul 2016, In: Nature. 535, 7610, p. 56-64 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

    Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, Raffield, L. M., Burt, A., Bartz, T. M., Becker, D. M., Becker, L. C., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., O'Donoghue, M. L., Crosslin, D. R., de Denus, S., Dubé, M., Elliott, P., Engström, G., Evans, M. K., Floyd, J. S., Fornage, M., Gao, H., Greinacher, A., Gudnason, V., Hansen, Torben, Harris, T. B., Hayward, C., Hernesniemi, J., Highland, H. M., Hirschhorn, J. N., Hofman, A., Irvin, M. R., Kähönen, M., Lange, E., Launer, L. J., Lehtimäki, T., Li, J., Liewald, D. C. M., Linneberg, Allan René, Liu, Y., Lu, Y., Lyytikäinen, L., Mägi, R., Mathias, R. A., Melander, O., Metspalu, A., Mononen, N., Nalls, M. A., Nickerson, D. A., Nikus, K., O'Donnell, C. J., Orho-Melander, M., Pedersen, Oluf Borbye, Petersmann, A., Polfus, L., Psaty, B. M., Raitakari, O. T., Raitoharju, E., Richard, M., Rice, K. M., Rivadeneira, F., Rotter, J. I., Schmidt, F., Smith, A. V., Starr, J. M., Taylor, K. D., Teumer, A., Thuesen, B. H., Torstenson, E. S., Tracy, R. P., Tzoulaki, I., Zakai, N. A., Vacchi-Suzzi, C., van Duijn, C. M., van Rooij, F. J. A., Cushman, M., Deary, I. J., Velez Edwards, D. R., Vergnaud, A., Wallentin, L., Waterworth, D. M., White, H. D., Wilson, J. G., Zonderman, A. B., Kathiresan, S., Grarup, N., Esko, T., Loos, R. J. F., Lange, L. A., Faraday, N., Abumrad, N. A., Edwards, T. L., Ganesh, S. K., Auer, P. L., Johnson, A. D., Reiner, A. P. & Lettre, G., 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Vaccinations against smallpox and tuberculosis are associated with better long-term survival: a Danish case-cohort study 1971-2010

    Rieckmann, Andreas, Villumsen, M., Sørup, S., Haugaard, L. K., Ravn, H., Roth, A., Baker, J. L., Benn, C. S. & Aaby, P., 5 Jul 2016, In: International Journal of Epidemiology. 2016, p. 1-11 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast

    Bak, A. M., Møller, A. B., Vendelbo, M. H., Nielsen, Thomas Svava, Viggers, R., Rungby, Jørgen, Pedersen, S. B., Jørgensen, J. O. L., Jessen, N. & Møller, N., 1 Jul 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 1, p. E224-35 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Early myocardial impairment in type 1 diabetes patients without known heart disease assessed with tissue Doppler echocardiography: The Thousand & 1 study

    Jensen, M. T., Søgaard, P., Andersen, H. U., Gustafsson, I., Bech, J., Hansen, T. F., Theilade, S., Almdal, Thomas Peter, Rossing, Peter & Jensen, J. S., Jul 2016, In: Diabetes and Vascular Disease Research. 13, 4, p. 260-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Majority of never-smokers with airflow limitation do not have asthma: the Copenhagen General Population Study

    Çolak, Y., Afzal, Shoaib, Nordestgaard, Børge & Lange, Peter, Jul 2016, In: Thorax. 71, 7, p. 614-623 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor

    Holst, Jens Juul & Madsbad, Sten, Jul 2016, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 12, 6, p. 1236-42 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Secretion of glucagon-like peptide-2 responds to nutrient intake but not glucose provision in milk-fed calves

    Castro, J. J., Morrison, S. Y., Hosseinni, A., Loor, J. J., Drackley, J. K., Ipharraguerre, I. R., Holst, Jens Juul & Hartmann, Bolette, Jul 2016, In: Journal of Dairy Science. 99, 7, p. 5793–5807

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Urinary biomarkers are associated with incident cardiovascular disease, all-cause mortality and deterioration of kidney function in type 2 diabetic patients with microalbuminuria

    von Scholten, B. J., Reinhard, H., Hansen, Tine Willum, Oellgaard, J., Parving, H., Jacobsen, P. K. & Rossing, Peter, Jul 2016, In: Diabetologia. 59, 7, p. 1549–1557

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

    Teumer, A., Qi, Q., Nethander, M., Aschard, H., Bandinelli, S., Beekman, M., Berndt, S. I., Bidlingmaier, M., Broer, L., Cappola, A., Ceda, G. P., Chanock, S., Chen, M-H., Chen, T. C., Chen, Y-D. I., Chung, J., Del Greco Miglianico, F., Eriksson, J., Ferrucci, L., Friedrich, N. & 31 others, Gnewuch, C., Goodarzi, M. O., Grarup, N., Guo, T., Hammer, E., Hayes, R. B., Hicks, A. A., Hofman, A., Houwing-Duistermaat, J. J., Hu, F., Hunter, D. J., Husemoen, L. L., Isaacs, A., Jacobs, K. B., Janssen, J. A. M. J. L., Jansson, J., Jehmlich, N., Johnson, S., Juul, Anders, Karlsson, M., Kilpeläinen, Tuomas O., Kovacs, P., Kraft, P., Li, C., Linneberg, Allan René, Liu, Y., Loos, Ruth, Lorentzon, M., Lu, Y., Maggio, M. & CHARGE Longevity Working Group, C. L. W. G., 29 Jun 2016, In: Aging Cell. 15, 5, p. 811-824 14 p., e1006166.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts

    Jelenkovic, A., Sund, R., Hur, Y-M., Yokoyama, Y., Hjelmborg, J. V. B., Möller, S., Honda, C., Magnusson, P. K. E., Pedersen, N. L., Ooki, S., Aaltonen, S., Stazi, M. A., Fagnani, C., D'Ippolito, C., Freitas, D. L., Maia, J. A., Ji, F., Ning, F., Pang, Z., Rebato, E. & 83 others, Busjahn, A., Kandler, C., Saudino, K. J., Jang, K. L., Cozen, W., Hwang, A. E., Mack, T. M., Gao, W., Yu, C., Li, L., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, Ruth, Heikkila, K., Wardle, J., Llewellyn, C. H., Fisher, A., McAdams, T. A., Eley, T. C., Gregory, A. M., He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Eaves, L. J., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Bartels, M., van Beijsterveldt, T. C. E. M., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Swan, G. E., Krasnow, R., Tynelius, P., Lichtenstein, P., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Spector, T., Mangino, M., Lachance, G., Baker, L. A., Tuvblad, C., Duncan, G. E., Buchwald, D., Willemsen, G., Skytthe, A., Kyvik, K. O., Christensen, K., Oncel, S. Y., Aliev, F., Rasmussen, F., Goldberg, J. H., Sørensen, Thorkild I.A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 23 Jun 2016, In: Scientific Reports. 6, p. 1-13 13 p., 28496.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Hypophosphatemia promotes lower rates of muscle ATP synthesis

    Pesta, D. H., Tsirigotis, D. N., Befroy, D. E., Caballero, D., Jurczak, M. J., Rahimi, Y., Cline, G. W., Dufour, S., Birkenfeld, A. L., Rothman, D. L., Carpenter, T. O., Insogna, K., Petersen, K. M. F., Bergwitz, C. & Shulman, G. I., 23 Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 10, p. 3378-3387 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

    Ziętak, M., Kovatcheva-Datchary, P., Markiewicz, L. H., Ståhlman, M., Kozak, L. P. & Bäckhed, G. F., 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1216-23 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Exercise Promotes Healthy Aging of Skeletal Muscle

    Cartee, G. D., Hepple, R. T., Bamman, M. M. & Zierath, Juleen R, 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1034-47 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndrome

    Perry, R. J., Peng, L., Barry, N. A., Cline, G. W., Zhang, D., Cardone, R. L., Petersen, K. F., Kibbey, R. G., Goodman, A. L. & Shulman, G. I., 9 Jun 2016, In: Nature. 534, 7606, p. 213-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

    Perry, R. J., Borders, C. B., Cline, G. W., Zhang, X., Alves, T. C., Petersen, K. M. F., Rothman, D. L., Kibbey, R. G. & Shulman, G. I., 3 Jun 2016, In: Journal of Biological Chemistry. 291, 23, p. 12161-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

    Koh, A., De Vadder, F., Kovatcheva-Datchary, P. & Bäckhed, G. F., 2 Jun 2016, In: Cell. 165, 6, p. 1332-45 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

    Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T. & 34 others, Linneberg, Allan René, Friedrich, N., Krarup, N. T., Fenger, M., Abildgaard, U., Hansen, Peter Riis, Galløe, A. M., Braund, P. S., Nelson, C. P., Hall, A. S., Williams, M. J. A., van Rij, A. M., Jones, G. T., Patel, R. S., Levey, A. I., Hayek, S., Shah, S. H., Reilly, M., Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, I., Kiemeney, L. A., Quyyumi, A. A., Rader, D. J., Kraus, W. E., Samani, N. J., Pedersen, Oluf Borbye, Thorgeirsson, G., Masson, G., Holm, H., Gudbjartsson, D., Sulem, P., Thorsteinsdottir, U. & Stefansson, K., 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2131-2141 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

    Scott, R. A., Freitag, D. F., Li, L., Chu, A. Y., Surendran, P., Young, R., Grarup, N., Stancakova, A., Chen, Y., Varga, T. V., Yaghootkar, H., Luan, J., Zhao, J. H., Willems, S. M., Wessel, J., Wang, S., Maruthur, N., Michailidou, K., Pirie, A., van der Lee, S. J. & 119 others, Gillson, C., Al Olama, A. A., Amouyel, P., Arriola, L., Arveiler, D., Aviles-Olmos, I., Balkau, B., Barricarte, A., Barroso, I., Garcia, S. B., Bis, J. C., Blankenberg, S., Boehnke, M., Boeing, H., Boerwinkle, E., Borecki, I. B., Bork-Jensen, J., Bowden, S., Caldas, C., Caslake, M., Cupples, L. A., Cruchaga, C., Czajkowski, J., den Hoed, M., Dunn, J. A., Earl, H. M., Ehret, G. B., Ferrannini, E., Ferrieres, J., Foltynie, T., Ford, I., Forouhi, N. G., Gianfagna, F., Gonzalez, C., Grioni, S., Hiller, L., Jansson, J., Jørgensen, M. E., Jukema, J. W., Kaaks, R., Kee, F., Kerrison, N. D., Key, T. J., Kontto, J., Kote-Jarai, Z., Kraja, A. T., Kuulasmaa, K., Kuusisto, J., Linneberg, Allan René, Liu, C., Marenne, G., Mohlke, K. L., Morris, A. P., Muir, K., Mueller-Nurasyid, M., Munroe, P. B., Navarro, C., Nielsen, S. F., Nilsson, P. M., Nordestgaard, B. G., Packard, C. J., Palli, D., Panico, S., Peloso, G. M., Perola, M., Peters, A., Poole, C. J., Quiros, J. R., Rolandsson, O., Sacerdote, C., Salomaa, V., Sanchez, M., Sattar, N., Sharp, S. J., Sims, R., Slimani, N., Smith, J. A., Thompson, D. J., Trompet, S., Tumino, R., van der A, D. L., van der Schouw, Y. T., Virtamo, J., Walker, M., Walter, K., Abraham, J. E., Amundadottir, L. T., Aponte, J. L., Butterworth, A., Dupuis, J., Easton, D. F., Eeles, R. A., Erdmann, J., Franks, P. W., Frayling, T. M., Hansen, Torben, Howson, J. M. M., Jørgensen, T., Kooner, J., Laakso, M., Langenberg, C., McCarthy, M. I., Pankow, J. S., Pedersen, Oluf Borbye, Riboli, E., Rotter, J. I., Saleheen, D., Samani, N. J., Schunkert, H., Vollenweider, P., O'Rahilly, S., Deloukas, P., Danesh, J., Goodarzi, M. O., Kathiresan, S., Meigs, J. B., Ehm, M. G., Wareham, N. J. & Waterworth, D. M., 1 Jun 2016, In: Science Translational Medicine. 8, 341, 13 p., 341ra76.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Erratum: Evidence of extrapancreatic glucagon secretion in man. Diabetes 2016;65:585-597

    Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jun 2016, In: Diabetes. 65, 6, p. 1752 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  60. Published

    Associations between birth weight and colon and rectal cancer risk in adulthood

    Smith, N. R., Jensen, B. W., Zimmermann, E., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., Jun 2016, In: Cancer Epidemiology. 42, p. 181-185 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion

    Hansen, M., Scheltema, M. J., Sonne, David Peick, Hansen, J. S., Sperling, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jun 2016, In: Diabetes, Obesity and Metabolism. 18, 6, p. 571-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Okbay, A., Baselmans, B. M. L., De Neve, J-E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F. W., Linnér, R. K., Rietveld, C. A., Derringer, J., Gratten, J., Lee, J. J., Liu, J. Z., de Vlaming, R., Ahluwalia, T. V. S., Buchwald, J., Cavadino, A., Frazier-Wood, A. C., Furlotte, N. A., Garfield, V. & 31 others, Geisel, M. H., Gonzalez, J. R., Haitjema, S., Karlsson, R., van der Laan, S. W., Ladwig, K., Lahti, J., van der Lee, S. J., Lind, P. A., Liu, T., Matteson, L., Mihailov, E., Miller, M. B., Minica, C. C., Nolte, I. M., Mook-Kanamori, D., van der Most, P. J., Oldmeadow, C., Qian, Y., Raitakari, O., Rawal, R., Realo, A., Rueedi, R., Schmidt, B., Smith, A. V., Stergiakouli, E., Tanaka, T., Bültmann, U., Hansen, Torben, Sørensen, Thorkild I.A. & LifeLines Cohort Study, L. C. S., Jun 2016, In: Nature Genetics. 48, 6, p. 624-33 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Open source non-invasive prenatal testing platform and its performance in a public health laboratory

    Johansen, P., Richter, S. R., Balslev-Harder, M., Miltoft, C. B., Tabor, Ann, Duno, M. & Kjærgaard, S., Jun 2016, In: Prenatal Diagnosis. 36, 6, p. 530-536 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Retinopathy is associated with impaired myocardial function assessed by advanced echocardiography in type 1 diabetes patients – The Thousand & 1 Study

    Nouhravesh, N., Andersen, H. U., Jensen, J. S., Rossing, Peter & Jensen, M. T., Jun 2016, In: Diabetes Research and Clinical Practice. 116, p. 263-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Roles of the Gut in Glucose Homeostasis

    Holst, Jens Juul, Gribble, F., Horowitz, M. & Rayner, C. K., Jun 2016, In: Diabetes Care. 39, 6, p. 884-92 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36

    Iepsen, E. W., Lundgren, J., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, Jun 2016, In: European Journal of Endocrinology. 174, 6, p. 775-784 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice

    Windeløv, Johanne Agerlin, Pedersen, Jens & Holst, Jens Juul, Jun 2016, In: Physiological Reports. 4, 11, 6 p., e12824.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice

    Trammell, Sam, Weidemann, B. J., Chadda, A., Yorek, M. S., Holmes, A., Coppey, L. J., Obrosov, A., Kardon, R. H., Yorek, M. A. & Brenner, C., 27 May 2016, In: Scientific Reports. 6, 26933.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Genome-wide association study identifies 74 loci associated with educational attainment

    Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G-B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P. N., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. V. S., Bacelis, J., Baumbach, C., Bjornsdottir, G. & 31 others, Brandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., deLeeuw, C., Lind, P. A., Lindgren, K., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., Bønnelykke, Klaus, Waage, J., Bisgaard, H., Sørensen, Thorkild I.A. & LifeLines Cohort Study, L. C. S., 26 May 2016, In: Nature. 533, 7604, p. 539-42 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  70. Published

    Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding

    Barington, L., Rummel, P. C., Lückmann, Michael, Pihl, H., Larsen, Olav, Daugvilaite, V., Johnsen, A. H., Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 19 May 2016, In: The Journal of Biological Chemistry. 291, 31, p. 16208-16220

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats

    Hoelmkjaer, K. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cronin, A. M., Nielsen, Dorte Hald, Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2 May 2016, In: P L o S One. 11, 5, 18 p., e0154727.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Anxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala

    Jensen, M., Ratner, C., Rudenko, Olga, Christiansen, S. H., Skov, Louise Julie, Johnsen, Cecilie Hundahl, Woldbye, David Paul Drucker & Holst, Birgitte, 1 May 2016, In: International Journal of Neuropsychopharmacology. 19, 5, 12 p., pyv123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses

    Rohde, U., Sonne, D. P., Christensen, M., Hansen, M., Brønden, A., Toräng, S., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 May 2016, In: The Journal of clinical endocrinology and metabolism. 101, 5, p. 2076-2083

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    FAP finds FGF21 easy to digest

    Gillum, M. P. & Potthoff, M. J., 1 May 2016, In: Biochemical Journal. 473, 9, p. 1125-7 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  76. Published

    Komplement C3 und risiko fur venose thromboembolie

    Nørgaard, I., Nielsen, S. F. & Nordestgaard, Børge, 1 May 2016, In: Vasomed. 28, 3, p. 134-135 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  77. Published

    Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217

    Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Nicotinamide riboside is a major NAD+ precursor vitamin in cow milk

    Trammell, Sam, Y., L., Redpath, P., Migaud, M. E. & Brenner, C., 1 May 2016, In: Journal of Nutrition. 146, 5, p. 957-963 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production

    Marzec, Michal Tomasz, Hawkes, C. P., Eletto, D., Boyle, S., Rosenfeld, R. G., Hwa, V., Wit, J. M., van Duyvenvoorde, H. A., Oostdijk, W., Losekoot, M., Pedersen, Oluf Borbye, Yeap, B. B., Flicker, L., Barzilai, N., Atzmon, G., Grimberg, A. & Argon, Y., May 2016, In: Endocrinology. 157, 5, p. 1914-1928 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

    Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 26 others, Halfvarson, J., Jensen, A. B., Lieb, W., Degenhardt, F., Forstner, A. J., Hofmann, A., Schreiber, S., Mrowietz, U., Juran, B. D., Lazaridis, K. N., Brunak, Søren, Dale, A. M., Trembath, R. C., Weidinger, S., Weichenthal, M., Ellinghaus, E., Elder, J. T., Barker, J. N. W. N., Andreassen, O. A., McGovern, D. P., Karlsen, T. H., Barrett, J. C., Parkes, M., Brown, M. A., Franke, A. & International IBD Genetics Consortium (IIBDGC), I. I. G. C. (., May 2016, In: Nature Genetics. 48, 5, p. 510-521 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Association of Pre-Pregnancy Body Mass Index, Pregnancy-Related Weight Changes, and Parity With the Risk of Developing Degenerative Musculoskeletal Conditions

    Bliddal, M., Pottegård, A., Kirkegaard, H., Olsen, J., Jørgensen, J. S., Sørensen, Thorkild I.A., Dreyer, L. & Nohr, E. A., May 2016, In: Arthritis & Rheumatism. 68, 5, p. 1156-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Combined insulin deficiency and endotoxin exposure stimulate lipid mobilization and alter adipose tissue signaling in an experimental model of ketoacidosis in subjects with type 1 diabetes: A randomized, controlled, cross over trial

    Svart, M., Kampmann, U., Voss, T., Pedersen, S. B., Johannsen, M., Rittig, N., Poulsen, P. L., Nielsen, Thomas Svava, Jessen, N. & Møller, N., May 2016, In: Diabetes. 65, 5, p. 1380-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia

    Junker, A. E., Gluud, Lise Lotte, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, May 2016, In: Journal of Internal Medicine. 279, 5, p. 485–493 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Effect of antibiotics on gut microbiota, glucose metabolism and bodyweight regulation: a review of the literature

    Mikkelsen, K. H., Allin, K. H. & Knop, Filip Krag, May 2016, In: Diabetes, Obesity and Metabolism. 18, 5, 444–453.

    Research output: Contribution to journal › Review › Research › peer-review

  85. Published

    Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112

    Cornelia Peeters, M., Mos, I., Lenselink, E. B., Lucchesi, M., IJzerman, A. P. & Schwartz, Thue W., May 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 5, p. 1836-1848 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy

    Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Sorensen, Charlotte Mehlin, Jonassen, Thomas & Bulow, J., May 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 9, p. E744-E753 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Observationally and Genetically High YKL-40 and Risk of Venous Thromboembolism in the General Population: Cohort and Mendelian Randomization Studies

    Kjaergaard, A. D., Johansen, Julia Sidenius, Bojesen, Stig Egil & Nordestgaard, Børge, May 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 5, p. 1030-1036 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

    Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity

    Larsen, S. C., Ängquist, Lars, Moldovan, M., Huikari, V., Sebert, S., Cavadino, A., Ahluwalia, Tarun Veer Singh, Skaaby, T., Linneberg, Allan René, Husemoen, L. L. N., Toft, U., Pedersen, Oluf Borbye, Hansen, T., Herzig, K., Jarvelin, M., Power, C., Hypponen, E., Heitmann, Berit & Sørensen, Thorkild I.A., 14 Apr 2016, In: P L o S One. 11, 4, p. 1-18 e0153611.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Increased Risk for Other Cancers in Addition to Breast Cancer for CHEK2*1100delC Heterozygotes Estimated From the Copenhagen General Population Study

    Näslund-Koch, C., Nordestgaard, Børge & Bojesen, Stig Egil, 10 Apr 2016, In: Journal of Clinical Oncology. 34, 11, p. 1208-16 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes

    Lund, M. T., Kristensen, M. D., Hansen, M., Tveskov, L., Floyd, A. K., Støckel, M., Vainer, B., Poulsen, Steen Seier, Helge, Jørn Wulff, Prats Gavalda, Clara & Dela, Flemming, 6 Apr 2016, In: The Journal of Physiology. 594, 15, p. 4351-4358 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Effects of endogenous GLP-1 and GIP on glucose tolerance after Roux-en-Y gastric bypass surgery

    Svane, M. S., Bojsen-Moller, K. N., Nielsen, S., Jørgensen, N. B., Dirksen, C., Bendtsen, Flemming, Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 1 Apr 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 7, p. E505-E514 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Searching for the physiological role of glucose-dependent insulinotropic polypeptide

    Holst, Jens Juul, Windeløv, Johanne Agerlin, Boer, G. A., Pedersen, Jens, Svendsen, B., Christensen, M., Torekov, Signe Sørensen, Asmar, M., Hartmann, Bolette & Nissen, A., 1 Apr 2016, In: Journal of Diabetes Investigation. 7, S1, p. 8-12 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Childhood body mass index and risk of schizophrenia in relation to childhood age, sex and age of first contact with schizophrenia

    Sørensen, H. J., Gamborg, Michael Orland, Sørensen, Thorkild I.A., Baker, J. L. & Mortensen, Erik Lykke, Apr 2016, In: European Psychiatry. 34, p. 64-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Childhood height, adult height, and the risk of prostate cancer

    Bjerregaard, L. G., Aarestrup, J., Gamborg, Michael Orland, Lange, Theis, Tjønneland, A. & Baker, J. L., Apr 2016, In: Cancer Causes & Control. 27, 4, p. 561-567 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Comparison of the long-term effects of LIiraglutide and Glimepiride monotherapy on bone mineral density in patients with type 2 diabetes

    Gilbert, M. P., Marre, M., Holst, Jens Juul, Garber, A., Baeres, F. M. M., Thomsen, H. & Pratley, R. E., Apr 2016, In: Endocrine Practice. 22, 4, p. 406-411 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Effects of glucagon-like peptide-1 on glucagon secretion in patients with non-alcoholic fatty liver disease

    Junker, A. E., Gluud, Lise Lotte, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Apr 2016, In: Journal of Hepatology. 64, 4, p. 908–915

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production

    Lee, Y. S., De Vadder, F., Tremaroli, V., Wichmann, A., Mithieux, G. & Bäckhed, G. F., Apr 2016, In: Molecular Metabolism. 5, 4, p. 263-70 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Levels of the inflammation marker YKL-40 in young adults exposed to intrauterine hyperglycemia

    Kelstrup, L., Dejgaard, T. F., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, drb459, drb459 & Damm, Peter, Apr 2016, In: Diabetes Research and Clinical Practice. 114, p. 50-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Liraglutide for treating type 1 diabetes

    Dejgaard, T. F., Frandsen, C. S., Holst, Jens Juul & Madsbad, Sten, Apr 2016, In: Expert Opinion on Biological Therapy. 16, 4, p. 579-90 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Peptide YY3-36 and glucagon-like peptide-1 in functional dyspepsia. Secretion and role in symptom generation

    Witte, A., Hilsted, Linda, Holst, Jens Juul & Schmidt, P. T., Apr 2016, In: Scandinavian Journal of Gastroenterology. 51, 4, p. 400-409 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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