Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2015
  2. Published

    Acute TNF-induced repression of cell identity genes is mediated by NFκB-directed redistribution of cofactors from super-enhancers

    Schmidt, S. F., Larsen, B. D., Loft, A., Nielsen, R., Madsen, J. G. S. & Mandrup, S., Sep 2015, In: Genome Research. 25, 9, p. 1281-94 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists

    Hansen, L. S., wbf943, wbf943, Svendsen, B., Christensen, M., Hartmann, Bolette, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Sep 2015, In: Diabetologia. 58, 1 supplement, p. S276-S277 2 p., 569.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  4. Published

    Important species differences regarding lymph contribution to gut hormone responses

    Hansen, M., Hjøllund, K. R., Hartmann, Bolette, Plamboeck, A., Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 28-31 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    No evidence of seasonality of birth in adult type 2 diabetes in Denmark

    Jensen, C. B., Zimmermann, E., Gamborg, Michael Orland, Heitmann, B. L., Baker, J. L., Vaag, Allan & Sørensen, Thorkild I.A., Sep 2015, In: Diabetologia. 58, 9, p. 2045-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Paternal chronic high-fat diet consumption reprogrammes the gametic epigenome and induces transgenerational inheritance of metabolic disorder

    Barbosa, T. D. C., Versteyhe, S., Alm, P., Ingerslev, L. R., Massart, J., Rasmussen, M., Donkin, I., Qian, K., Sjogren, R., Mudry, J. M., Vetterli, L., Gup, S., Krook, A., Zierath, Juleen R & Barrès, Romain, Sep 2015, In: Diabetologia. 58, Issue 1 Supplement, p. S162-S163 2 p., 323.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  8. Published

    The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Association study between CDH2 and Gilles de la Tourette syndrome in a Danish cohort

    Nazaryan, L., Bertelsen, B., Padmanabhuni, S. S., Debes, N. M., LuCamp, L., Have, C. T. & Tümer, Asuman Zeynep, 30 Aug 2015, In: Psychiatry Research. 228, 3, p. 974-5 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  10. Published

    The disruption of mitochondrial axonal transport is an early event in neuroinflammation

    Errea, O., Moreno, B., Gonzalez-Franquesa, A., Garcia-Roves, P. M. & Villoslada, P., 28 Aug 2015, In: Journal of Neuroinflammation. 12, p. 152

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells

    Wu, B., Wei, S., Petersen, N., Ali, Y., Wang, X., Bacaj, T., Rorsman, P., Hong, W., Südhof, T. C. & Han, W., 11 Aug 2015, In: National Academy of Sciences. Proceedings. 112, 32, p. 9996-10001 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    NNMT: A Bad Actor in Fat Makes Good in Liver

    Trammell, Sam & Brenner, C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 200-201 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  13. Published

    Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

    Shoaie, S., Ghaffari, P., Kovatcheva-Datchary, P., Mardinoglu, A., Sen, P., Pujos-Guillot, E., de Wouters, T., Juste, C., Rizkalla, S., Chilloux, J., Hoyles, L., Nicholson, J. K., Dore, J., Dumas, M. E., Clement, K., Bäckhed, G. F., Nielsen, J. & MICRO-Obes Consortium, M. C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 320-31 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

    Tremaroli, V., Karlsson, F., Werling, M., Ståhlman, M., Kovatcheva-Datchary, P., Olbers, T., Fändriks, L., le Roux, C. W., Nielsen, J. & Bäckhed, G. F., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 228-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young

    Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Childhood maltreatment and obesity

    Sørensen, Thorkild I.A., Aug 2015, In: Obesity. 23, 8, p. 1528 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  17. Published

    Diabetologia at 50: celebrating half a century of progress in diabetes research and care

    Zierath, Juleen R, Aug 2015, In: Diabetologia. 58, 8, p. 1685-7 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  18. Published

    Exploring possible epigenetic mediation of early-life environmental exposures on adiposity and obesity development

    Richmond, R. C., Timpson, N. J. & Sørensen, Thorkild I.A., Aug 2015, In: International Journal of Epidemiology. 44, 4, p. 1191-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits

    Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Garaulet, M., Gottlieb, D. J., Hruby, A., Jacques, P. F., Kiefte-de Jong, J. C., Lamon-Fava, S., Scheer, F. A. J. L., Bartz, T. M., Kovanen, L., Wojczynski, M. K., Frazier-Wood, A. C., Ahluwalia, T. V. S., Perälä, M-M., Jonsson, A., Muka, T., Kalafati, I. P. & 3 others, Mikkilä, V., Ordovás, J. M. & CHARGE Nutrition Study Group, C. N. S. G., Aug 2015, In: Diabetes Care. 38, 8, p. 1456-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model

    Amrutkar, M., Cansby, E., Chursa, U., Nuñez-Durán, E., Chanclón, B., Ståhlman, M., Fridén, V., Mannerås-Holm, L., Wickman, A., Smith, U., Bäckhed, G. F., Borén, J., Howell, B. W. & Mahlapuu, M., Aug 2015, In: Diabetes. 64, 8, p. 2791-804 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Heparin treatment increases thioredoxin interacting protein expression in hepatocellular carcinoma cells

    Gunes, A., Iscan, E., Topel, Hande, Avci, S. T., Gumustekin, M., Erdal, E. & Atabey, N., Aug 2015, In: The International Journal of Biochemistry & Cell Biology. 65, p. 169-81 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Heritability of gestational weight gain: a Swedish register-based twin study

    Andersson, E. S., Silventoinen, K., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., Aug 2015, In: Twin Research and Human Genetics. 18, 4, p. 410-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Maternal prepregnancy waist circumference and BMI in relation to gestational weight gain and breastfeeding behavior: the CARDIA study

    Kirkegaard, H., Nohr, E. A., Rasmussen, K. M., Stovring, H., Sørensen, Thorkild I.A., Lewis, C. E. & Gunderson, E. P., Aug 2015, In: The American Journal of Clinical Nutrition. 102, 2, p. 393-401 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Prognostic clinical and molecular biomarkers of renal disease in type 2 diabetes

    Pena, M. J., de Zeeuw, D., Mischak, H., Jankowski, J., Oberbauer, R., Woloszczuk, W., Benner, J., Dallmann, G., Mayer, B., Mayer, G., Rossing, Peter & Lambers Heerspink, H. J., Aug 2015, In: Nephrology, Dialysis, Transplantation. 30, Suppl 4, p. iv86-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits

    Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., Tarnoki, A. D., Tarnoki, D. L., Ning, F., Ji, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A. & 106 others, Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D'Ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freitas, D. L., Maia, J. A., Harden, K. P., Tucker-Drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Hong, C., Chong, Y., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Song, Y., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Heikkilä, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C. H., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Rasmussen, F., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Boomsma, D. I., Hur, Y., Sørensen, Thorkild I.A. & Kaprio, J., Aug 2015, In: Twin Research and Human Genetics. 18, 4, p. 348-60 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Directional dominance on stature and cognition in diverse human populations

    Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V., Trompet, S. & 31 others, Guo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Traglia, M., Farmaki, A., Kacprowski, T., Bjonnes, A., van der Spek, A., Wu, Y., Giri, A. K., Yanek, L. R., Wang, L., Hofer, E., Rietveld, C. A., McLeod, O., Cornelis, M. C., Pattaro, C., Verweij, N., Baumbach, C., Abdellaoui, A., Warren, H. R., Ahluwalia, Tarun Veer Singh, Melbye, M., Bisgaard, H., Sørensen, Thorkild I.A. & BioBank Japan Project, B. J. P., 23 Jul 2015, In: Nature. 523, p. 459-62 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  27. Published

    Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes

    Thomsen, S. B., Gjesing, A. M. P., Rathcke, C. N., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 21 Jul 2015, In: PLOS ONE. 10, 7, p. 1-10 10 p., e0133672.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo.

    Toräng, S., Veedfald, Simon, Rosenkilde, Mette, Hartmann, Bolette & Holst, Jens Juul, 20 Jul 2015, In: Physiological Reports. 3, 7, p. 1-8 8 p., e12455.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Inhibitors of histone deacetylase

    Holson, E., Wagner, F. F., Haggarty , S. J., Zhang , Y., Lundh, M., Wagner , B. & Lewis , M. C., 9 Jul 2015, IPC No. A61K31/167, Patent No. PCT/US2013/052572, 29 Jul 2013, Priority date 27 Jul 2012, Priority No. US201314417477 20130729 ; US201261676496P 20120727 ; WO2013US52572 20130729

    Research output: Patent

  30. Published

    Looking Ahead Perspective: Where Will the Future of Exercise Biology Take Us?

    Zierath, Juleen R & Wallberg-Henriksson, H., 7 Jul 2015, In: Cell Metabolism. 22, 1, p. 25-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

    Rönn, T., Volkov, P., Gillberg, L., Kokosar, M., Perfilyev, A., Jacobsen, A. L., Jørgensen, S. W., Brøns, C., Jansson, P., Eriksson, K., Pedersen, Oluf Borbye, Hansen, Torben, Groop, L., Stener-Victorin, E., Vaag, Allan, Nilsson, E. & Ling, C., 1 Jul 2015, In: Human Molecular Genetics. 24, 13, p. 3792-813 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Childhood height increases the risk of prostate cancer mortality

    Aarestrup, J., Gamborg, Michael Orland, Cook, M. B. & Baker, J. L., Jul 2015, In: European Journal of Cancer. 51, 10, p. 1340-1345 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents

    Qi, Q., Downer, M. K., Oskari Kilpeläinen, T., Taal, H. R., Barton, S. J., Ntalla, I., Standl, M., Boraska, V., Huikari, V., Kiefte-de Jong, J. C., Körner, A., Lakka, T. A., Liu, G., Magnusson, J., Okuda, M., Raitakari, O., Richmond, R., Scott, R. A., Bailey, M. E. S., Scheuermann, K. & 22 others, Holloway, J. W., Inskip, H., Isasi, C. R., Mossavar-Rahmani, Y., Jaddoe, V. W. V., Laitinen, J., Lindi, V., Melén, E., Pitsiladis, Y., Pitkänen, N., Snieder, H., Heinrich, J., Timpson, N. J., Wang, T., Yuji, H., Zeggini, E., Dedoussis, G. V., Kaplan, R. C., Wylie-Rosett, J., Loos, R. J. F., Hu, F. B. & Qi, L., Jul 2015, In: Diabetes. 64, 7, p. 2467-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1

    Manfra, O., Van Craenenbroeck, K., Skieterska, K., Frimurer, Thomas Michael, Schwartz, Thue W., Levy, F. O. & Andressen, K. W., Jul 2015, In: A C S Chemical Neuroscience. 6, 7, p. 1206–1218 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Energy balance measurement: when something is not better than nothing

    Dhurandhar, N. V., Schoeller, D., Brown, A. W., Heymsfield, S. B., Thomas, D., Sørensen, Thorkild I.A., Speakman, J. R., Jeansonne, M., Allison, D. B., Astrup, A. & Energy Balance Measurement Working Group, E. B. M. W. G., Jul 2015, In: International journal of obesity (2005). 39, p. 1109-13 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study

    Færch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbæk, A., Holst, Jens Juul & Jørgensen, M. E., Jul 2015, In: Diabetes. 64, p. 2513-25 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

    Lundh, M., Galbo, T., Poulsen, Steen Seier & Mandrup-Poulsen, Thomas, Jul 2015, In: Diabetes, Obesity and Metabolism. 17, 7, p. 703-7 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  38. Published

    Neuromedin U inhibits food intake partly by inhibiting gastric emptying

    Dalbøge, L. S., Pedersen, S. L., Secher, T., Holst, Birgitte, Vrang, N. & Jelsing, J., Jul 2015, In: Peptides. 69, p. 56-65 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Accelerated food source location in aging Drosophila.

    Egenriether, S., Chow, E., Krauth, Nathalie & Giebultowicz, J., 23 Jun 2015, In: Aging Cell.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals

    Krarup, N. T., Borglykke, A., Allin, K. H., Sandholt, C. H., Justesen, Johanne Marie, Andersson, E. A., Grarup, N., Jørgensen, T., Pedersen, O. & Hansen, T., Jun 2015, In: Atherosclerosis. 240, 2, p. 305-10 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

    Yaghootkar, H., Stancáková, A., Freathy, R. M., Vangipurapu, J., Weedon, M. N., Xie, W., Wood, A. R., Ferrannini, E., Mari, A., Ring, S. M., Lawlor, D. A., Davey Smith, G., Jørgensen, T., Hansen, T., Pedersen, O., Steinthorsdottir, V., Guðbjartsson, D. F., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K. & 7 others, Hattersley, A. T., Walker, M., Morris, A. D., McCarthy, M. I., Palmer, C. N. A., Laakso, M. & Frayling, T. M., Jun 2015, In: Diabetes. 64, 6, p. 2279-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Does menopausal hormone therapy reduce myocardial infarction risk if initiated early after menopause? A population-based case-control study

    Carrasquilla, Germán D., Berglund, A., Gigante, B., Landgren, B., de Faire, U., Hallqvist, J. & Leander, K., Jun 2015, In: Menopause . 22, 6, p. 598-606

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study

    Schopman, J. E., Hoekstra, J. B. L., Frier, B. M., Ackermans, M. T., de Sonnaville, J. J. J., Stades, A. M., Zwertbroek, R., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Holleman, F., Jun 2015, In: Diabetes, Obesity and Metabolism. 17, 6, p. 546-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    One-year high fat diet affects muscle-but not brain mitochondria

    Joergensen, T., Grunnet, N. & Quistorff, B., Jun 2015, In: Journal of Cerebral Blood Flow and Metabolism. 35, 6, p. 943-950 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Secular trends in seasonal variation in birth weight

    B. Jensen, C., Gamborg, Michael Orland, Raymond, K., McGrath, J., Sørensen, Thorkild I.A. & Heitmann, Berit, Jun 2015, In: Early Human Development. 91, 6, p. 361-365 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Stable intergenerational associations of childhood overweight during the development of the obesity epidemic

    Ajslev, T. A., Ängquist, Lars, Silventoinen, K., Baker, J. L. & Sørensen, Thorkild I.A., Jun 2015, In: Obesity. 23, 6, p. 1279-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Specific gut microbiota features and metabolic markers in postmenopausal women with obesity

    Brahe, L. K., Le Chatelier, E., Prifti, E., Pons, N., Kennedy, S., Hansen, Torben, Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. D. & Larsen, L. H., 15 May 2015, In: Nutrition and Diabetes. 5, 7 p., e159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Central serotonergic neurons activate and recruit thermogenic brown and beige fat and regulate glucose and lipid homeostasis

    McGlashon, J. M., Gorecki, M. C., Kozlowski, A. E., Thirnbeck, C. K., Markan, K. R., Leslie, K. L., Kotas, M. E., Potthoff, M. J., Richerson, G. B. & Gillum, M. P., May 2015, In: Cell Metabolism. 21, 5, p. 692-705 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data

    Gjesing, A. M. P., Ribel-Madsen, R., Harder, M. N., Eiberg, Hans Rudolf Lytchoff, Grarup, N., Jørgensen, T., Ekstrøm, Claus Thorn, Pedersen, Oluf Borbye & Hansen, Torben, May 2015, In: Diabetologia. 58, 5, p. 1006-1012 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Hypoglycemia-associated changes in the electroencephalogram in patients with type 1 diabetes and normal hypoglycemia awareness or unawareness

    Sejling, A., Kjær, T. W., Pedersen-Bjergaard, Ulrik, Diemar, S. S., Frandsen, C. S. S., Hilsted, L., Faber, Jens, Holst, Jens Juul, Tarnow, L., Nielsen, M. N., Remvig, L. S., Thorsteinsson, B. & Juhl, C. B., May 2015, In: Diabetes. 64, 5, p. 1760-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    NKG2D-Dependent Activation of Dendritic Epidermal T cells in Contact Hypersensitivity

    Nielsen, M. M., Dyring-Andersen, Beatrice, Schmidt, J. D., Witherden, D., Lovato, P., Woetmann, Anders , Ødum, Niels, Poulsen, Steen Seier, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, May 2015, In: Journal of Investigative Dermatology. 135, 5, p. 1311-19 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Risk of Breast Cancer in Relation to Combined Effects of Hormone Therapy, Body Mass Index, and Alcohol Use, by Hormone-receptor Status

    Hvidtfeldt, U. A., Tjønneland, Anne, Keiding, N., Lange, Theis, Andersen, Ingelise, Sørensen, Thorkild I.A., Prescott, Eva, Hansen, Åse Marie, Gronbaek, M., Bojesen, Stig Egil, Diderichsen, Finn & Rod, Naja Hulvej, May 2015, In: Epidemiology. 26, 3, p. 353-361

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator

    Husby, S., Ralfkiaer, U., Garde, C., Zandi, R., Ek, S., Kolstad, A., Jerkeman, M., Laurell, A., Räty, R., Pedersen, L. B., Pedersen, A., Ehinger, M., Sundström, C., Karjalainen-Lindsberg, M-L., Delabie, J., Clasen-Linde, E., Brown, P. D. N., Cowland, J. B., Workman, C. T., Geisler, C. H. & 1 others, Grønbæk, Kirsten, 23 Apr 2015, In: Blood. 125, 17, p. 2669-77 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2 leading to cell depolarization and calcium influx

    Kuhre, Rune Ehrenreich, Bechmann, L. E., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 21 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 12, p. E1123–E1130 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

    Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, von Holstein-Rathlou, Niels-Henrik, Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In: A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Renal Extraction and Acute Effects of Glucagon-like peptide-1 on Central and Renal Hemodynamics in Healthy Men

    Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Jonassen, Thomas & Bülow, J., 15 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 8, p. E641-E649 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery

    Lund, M. T., Hansen, M., Skaaby, Stinna, Dalby, S., Støckel, M., Floyd, A. K., Bech, K., Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 13 Apr 2015, In: The Journal of Physiology. 593, 14, p. 3123-33 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals

    Haahr, M. E., Hansen, D. L., Fisher, P. M., Svarer, C., Stenbæk, D. S., Madsen, K., Madsen, J., Holst, Jens Juul, Baaré, W. F. C., Højgaard, Liselotte, Almdal, T. & Knudsen, G. M., 8 Apr 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 14, p. 5884-5889 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Impaired oxidative capacity due to decreased CPT1b levels as a contributing factor to fat accumulation in obesity

    Ratner, C., Madsen, A. N., Kristensen, L. V., Skov, Louise Julie, Pedersen, K. S., Mortensen, Ole Hartvig, Knudsen, Gitte Moos, Raun, K. & Holst, Birgitte, 8 Apr 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 308, 11, p. R973-R982 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia

    Nøhr, M. K., Egerod, Kristoffer Lihme, Christiansen, S. H., Gille, A., Offermanns, S., Schwartz, Thue W. & Møller, Morten, 2 Apr 2015, In: Neuroscience. 290, p. 126-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Alterations in molecular muscle mass regulators after 8 days immobilizing Special Forces mission

    Jespersen, J. G., Mikkelsen, U. R., Nedergaard, A., Thorlund, J. B., Schjerling, Peter, Suetta, Charlotte, Christensen, P. A. & Aagaard, P., Apr 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 2, p. 175-183 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease

    Ádori, C., Glück, L., Barde, S., Yoshitake, T., Kovacs, G. G., Mulder, J., Maglóczky, Z., Havas, L., Bölcskei, K., Mitsios, N., Uhlén, M., Szolcsányi, J., Kehr, J., Rönnbäck, A., Schwartz, Thue W., Rehfeld, Jens Frederik, Harkany, T., Palkovits, M., Schulz, S. & Hökfelt, T., Apr 2015, In: Acta Neuropathologica. 129, 4, p. 541-63 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study

    Bohl, M., Bjørnshave, A., Rasmussen, K. V., Schioldan, A. G., Amer, B., Larsen, M. K., Dalsgaard, T. K., Holst, Jens Juul, Herrmann, A., O'Neill, S., O'Driscoll, L., Afman, L., Jensen, E., Christensen, M. M., Gregersen, S. & Hermansen, K., Apr 2015, In: The American Journal of Clinical Nutrition. 101, 4, p. 870-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways and transcription factors

    Deshmukh, Atul Shahaji, Murgia, M., Nagaraja, N., Treebak, Jonas Thue, Cox, J. & Mann, Matthias, Apr 2015, In: Molecular and Cellular Proteomics. 14, 4, p. 841-853

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes

    Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, N. & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Global Longitudinal Strain Is Not Impaired in Type 1 Diabetes Patients Without Albuminuria: The Thousand & 1 Study

    Jensen, M. T., Sogaard, P., Andersen, H. U., Bech, J., Fritz Hansen, T., Biering-Sørensen, Tor, Jørgensen, P. G., Galatius, S., Madsen, J. K., Rossing, Peter & Jensen, J. S., Apr 2015, In: J A C C: Cardiovascular Imaging. 8, 4, p. 400-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors

    Hamann, J., Aust, G., Araç, D., Engel, F. B., Formstone, C., Fredriksson, R., Hall, R. A., Harty, B. L., Kirchhoff, C., Knapp, B., Krishnan, A., Liebscher, I., Lin, H-H., Martinelli, D. C., Monk, K. R., Cornelia Peeters, M., Piao, X., Prömel, S., Schöneberg, T., Schwartz, T. W. & 9 others, Singer, K., Stacey, M., Ushkaryov, Y. A., Vallon, M., Wolfrum, U., Wright, M. W., Xu, L., Langenhan, T. & Schiöth, H. B., Apr 2015, In: Pharmacological Reviews. 67, 2, p. 338-67 30 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults

    Zimmermann, E., Ängquist, L. H., Mirza, S. S., Zhao, J. H., Chasman, D. I., Fischer, K., Qi, Q., Smith, A. V., Thinggaard, M., Jarczok, M. N., Nalls, M. A., Trompet, S., Timpson, N. J., Schmidt, B., Jackson, A. U., Lyytikäinen, L. P., Verweij, N., Mueller-Nurasyid, M., Vikström, M., Marques-Vidal, P. & 31 others, Wong, A., Meidtner, K., Middelberg, R. P., Strawbridge, R. J., Christiansen, L., Kyvik, K. O., Hamsten, A., Jääskeläinen, T., Tjønneland, A., Eriksson, J. G., Whitfield, J. B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K., Peters, A., van der Harst, P., Kumari, M., Lehtimäki, T., Meirhaeghe, A., Tuomilehto, J., Jöckel, K., Ben-Shlomo, Y., Sattar, N., Baumeister, S. E., Davey Smith, G., Casas, J. P., Houston, D. K., März, W., Sørensen, Thorkild I.A. & FTO-Mortality Collaborating Group, F. C. G., Apr 2015, In: Obesity Reviews. 16, 4, p. 327-40 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Maternal weight change from prepregnancy to 7 years postpartum: the influence of behavioral factors

    Kirkegaard, H., Stovring, H., Rasmussen, K. M., Abrams, B., Sørensen, Thorkild I.A. & Nohr, E. A., Apr 2015, In: Obesity. 23, 4, p. 870-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Patients with psoriasis are insulin resistant

    Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics

    Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data

    Madsen, J. G. S., Schmidt, S. F., Larsen, B. D., Loft, A., Nielsen, R. & Mandrup, S., 31 Mar 2015, In: Nucleic Acids Research. 43, 6, p. 1-9 9 p., e40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes

    Hansen, T. H., drb459, drb459, Jørgensen, T., Jørgensen, M. E., Lauritzen, T., Brandslund, I., Christensen, C., Pedersen, Oluf Borbye, Hansen, Torben & Gjesing, A. M. P., 20 Mar 2015, In: BMC Medical Genetics. 16, p. 1-9 9 p., 17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    No association of maternal gestational weight gain with offspring blood pressure and hypertension at age 18 years in male sibling-pairs: a prospective register-based cohort study

    Scheers Andersson, E., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., 20 Mar 2015, In: PLOS ONE. 10, 3, p. 1-12 12 p., e0121202.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals

    Nead, K. T., Li, A., Wehner, M. R., Neupane, B., Gustafsson, S., Butterworth, A., Engert, J. C., Davis, A. D., Hegele, R. A., Miller, R., den Hoed, M., Khaw, K-T., Oskari Kilpeläinen, T., Wareham, N., Edwards, T. L., Hallmans, G., Varga, T. V., Kardia, S. L. R., Smith, J. A., Zhao, W. & 31 others, Faul, J. D., Weir, D., Mi, J., Xi, B., Canizales Quinteros, S., Cooper, C., Sayer, A. A., Jameson, K., Grøntved, A., Fornage, M., Sidney, S., Hanis, C. L., Highland, H. M., Häring, H., Heni, M., Lasky-Su, J., Weiss, S. T., Gerhard, G. S., Still, C., Melka, M. M., Pausova, Z., Paus, T., Grant, S. F. A., Hakonarson, H., Price, R. A., Wang, K., Scherag, A., Hebebrand, J., Hinney, A., Franks, P. W. & BioBank Japan, B. J., 17 Mar 2015, In: Human Molecular Genetics. 24, 2, p. 3582–3594 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass

    Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    AMP-activated protein kinase controls exercise training- and AICAR-induced increases in SIRT3 and MnSOD

    Brandauer, J., Andersen, M. A., Kellezi, H., Risis, S., Frøsig, C., Vienberg, S. G. & Treebak, Jonas Thue, Mar 2015, In: Frontiers in Physiology. 6, 16 p., 85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine

    Svendsen, B., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Toräng, S., Rehfeld, Jens Frederik, Poulsen, Steen Seier & Holst, Jens Juul, Mar 2015, In: Endocrinology. 156, 3, p. 847-857 11 p., en20141710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Circulating miR-192 and miR-193b are markers of prediabetes and are modulated by an exercise intervention

    Párrizas, M., Brugnara, L., Esteban, Y., González-Franquesa, A., Canivell, S., Murillo, S., Gordillo-Bastidas, E., Cussó, R., Cadefau, J. A., García-Roves, P. M., Servitja, J. & Novials, A., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E407-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients

    Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    DISEASES: Text mining and data integration of disease-gene associations

    Pletscher-Frankild, S., Pallejà, A., Tsafou, K., Binder, J. X. & Jensen, Lars Juhl, Mar 2015, In: Methods. 74, p. 83-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice

    Clemmensen, Christoffer, Finan, B., Fischer, K., Tom, R. Z., Legutko, B., Sehrer, L., Heine, D., Grassl, N., Meyer, C. W., Henderson, B., Hofmann, S. M., Tschöp, M. H., Van der Ploeg, L. H. T. & Müller, T. D., Mar 2015, In: EMBO Molecular Medicine. 7, 3, p. 288-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Kristiansen, V. B., Wulff, B. S., Rainteau, D., Humbert, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Clausen, T. R., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E396-406 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Incretin effect after oral amino Acid ingestion in humans

    Lindgren, O., Pacini, G., Tura, A., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 1172-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes

    Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., Mar 2015, In: Diabetes. 64, 3, p. 673-86 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Placenta accreta: adherent placenta due to Asherman syndrome

    pjx571, pjx571, Langhoff-Roos, J., Kjer, J. J. & Istre, O., Mar 2015, In: Clinical Case Reports. 3, 3, p. 175 178 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium

    Sommer, F. & Bäckhed, G. F., Mar 2015, In: Mucosal Immunology. 8, 2, p. 372-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population

    Justesen, Johanne Marie, Allin, K. H., Sandholt, C. H., Borglykke, A., Krarup, N. T., Grarup, N., Linneberg, Allan René, Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 24 Feb 2015, In: Circulation. Cardiovascular genetics. 8, p. 465-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    A novel common variant in DCST2 is associated with length in early life and height in adulthood

    van der Valk, R. J. P., Kreiner-Møller, E., Kooijman, M. N., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J. P., Geller, F., Hayes, M. G., Cousminer, D. L., Körner, A., Thiering, E., Curtin, J. A., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N. M., Pitkänen, N., Ntalla, I. & 31 others, Horikoshi, M., Veijola, R., Freathy, R. M., Teo, Y., Barton, S. J., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Davey Smith, G., Bergström, A., Kull, I., Hakonarson, H., Mentch, F. D., Bisgaard, H., Chawes, Bo Lund Krogsgaard, Stokholm, Jakob, Waage, J., Eriksen, P., Sevelsted, A., Melbye, M., van Duijn, C. M., Medina-Gomez, C., Hofman, A., de Jongste, J. C., Taal, H. R., Uitterlinden, A. G., Armstrong, L. L., Pers, Tune H, Bønnelykke, Klaus & Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, E. G. A. L. E. (. C., 15 Feb 2015, In: Human Molecular Genetics. 24, 4, p. 1155-68 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Optimisation of in silico derived 2-aminobenzimidazole hits as unprecedented selective kappa opioid receptor agonists

    Sasmal, P. K., Krishna, C. V., Sudheerkumar Adabala, S., Rawoof, K. A., Thadi, A., Sukumar, K. P., Cheera, S., Abbineni, C., Rao, K. V. L. N., Prasanthi, A., Nijhawan, K., Jaleel, M., Ramachandran Iyer, L., Chaitanya, T. K., Tiwari, N. K., Krishna, N. L., Potluri, V., Khanna, I., Frimurer, T. M., Lückmann, M. & 3 others, Rist, Ø., Elster, L. & Högberg, T., 15 Feb 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 4, p. 887-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Genetic studies of body mass index yield new insights for obesity biology

    Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Mägi, R., Randall, J. C., Winkler, T. W. & 31 others, Wood, A. R., Workalemahu, T., Faul, J. D., Smith, J. A., Hua Zhao, J., Zhao, W., Chen, J., Fehrmann, R., Hedman, Å. K., Karjalainen, J., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bolton, J. L., Bragg-Gresham, J. L., Buyske, S., Demirkan, A., Deng, G., Ehret, G. B., Feenstra, B., Feitosa, M. F., Fischer, K., Goel, A., Gong, J., Jackson, A. U., Schwarz, Peter, Melbye, M., Njølstad, I. & LifeLines Cohort Study, L. C. S., 12 Feb 2015, In: Nature. 518, 7538, p. 197-206 24 p., 14177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    GLP-1 defects in diabetes

    Janus, C., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2 Feb 2015

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  94. Published

    First report on intraoperative vector flow imaging of the heart among patients with healthy and diseased aortic valves

    Hansen, Kristoffer Lindskov, Møller-Sørensen, H., Pedersen, M. M., Hansen, P. M., Kjærgaard, Jesper, Lund, Jens, Nilsson, J. C., Jensen, J. A. & Nielsen, Michael Bachmann, 1 Feb 2015, In: Ultrasonics. 56, p. 243-250 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    In vivo efficacy of HD0471953: A novel GPR119 agonist for the treatment of type 2 diabetes mellitus

    'T Hart, L. M., Fritsche, A., Nijpels, G., Van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N., Van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., MacHicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M. H., Holst, Jens Juul, De Koning, E. J., Häring, H. U., Pedersen, O., Groop, L., De Geus, E. J., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M., Pearson, E. R. & Diamant, M., 1 Feb 2015, In: Diabetes Technology & Therapeutics. 17, p. S131-S133

    Research output: Contribution to journalComment/debateResearchpeer-review

  96. Published

    Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes

    Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 207-210 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  97. Published

    Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

    Hu, Z., Zhu, D., Wang, W., Li, W., Jia, W., Zeng, X., Ding, W., Yu, L., Wang, X., Wang, L., Shen, H., Zhang, C., Liu, H., Liu, X., Zhao, Y., Fang, X., Li, S., Chen, W., Tang, T., Fu, A. & 16 others, Wang, Z., Chen, G., Gao, Q., Li, S., Xi, L., Wang, C., Liao, S., Ma, X., Wu, P., Li, K., Wang, S., Zhou, J., Wang, J., Xu, X., Wang, H. & Ma, D., Feb 2015, In: Nature Genetics. 47, 2, p. 158-63, 2 unpag. pages 8 p.

    Research output: Contribution to journalLetterResearchpeer-review

  98. Published

    Intact Pituitary Function is Decisive for the Catabolic Response to TNF-α: Studies of Protein, Glucose and Fatty Acid Metabolism in Hypopituitary and Healthy Subjects

    Bach, E., Møller, A. B., Jørgensen, J. O. L., Vendelbo, M. H., Jessen, N., Olesen, J. F., Pedersen, S. B., Nielsen, Thomas Svava & Møller, N., Feb 2015, In: The Journal of clinical endocrinology and metabolism. 100, 2, p. 578-86 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Maternal salivary cortisol levels during pregnancy are positively associated with overweight children

    Hohwü, L., Henriksen, T. B., Grønborg, T. K., Hedegaard, M., Sørensen, Thorkild I.A. & Obel, C., Feb 2015, In: Psychoneuroendocrinology. 52, p. 143-152 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice

    Brandt, C., Hansen, R. H., Hansen, J. B., Olsen, C. H., Galle, P., Mandrup-Poulsen, Thomas, Gehl, Julie, Pedersen, Bente Klarlund & Hojman, P., Feb 2015, In: Metabolism. 64, 2, p. 283-295 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review