- 2015
- Published
Updates in weight loss surgery and gastrointestinal peptides
Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Peptidomics combined with cDNA library unravel the diversity of centipede venom
Rong, M., Yang, S., Wen, B., Mo, G., Kang, D., Liu, J., Lin, Z., Jiang, W., Li, B., Du, C., Yang, S., Jiang, H., Feng, Q., Xu, X., Wang, J. & Lai, R., 30 Jan 2015, In: Journal of Proteomics. 114, 1, p. 28-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, , 29 Jan 2015, In: Nature Communications. 6, p. 5897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas
Christiansen, Charlotte Bayer, Svendsen, B. & Holst, Jens Juul, 20 Jan 2015, In: Hormone and Metabolic Research. 47, 07, p. 537-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol
Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of glucagon-like peptide-1 and glucagon in human plasma
Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum:Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression (Cell (2014) 159 (33-45))
Agudelo, L. Z., Femenía, T., Orhan, F., Porsmyr-Palmertz, M., Goiny, M., Martinez-Redondo, V., Correia, J. C., Izadi, M., Bhat, M., Schuppe-Koistinen, I., Pettersson, A., Ferreira, D. M. S., Krook, A., Barrès, Romain, Zierath, Juleen R, Erhardt, S., Lindskog, M. & Ruas, J. L., 15 Jan 2015, In: Cell. 160, 1-2, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
HDAC Inhibitor-Mediated Beta-Cell Protection Against Cytokine-Induced Toxicity Is STAT1 Tyr701 Phosphorylation Independent
Dahllöf, M. S., Christensen, D. P., Harving, M., Wagner, B. K., Mandrup-Poulsen, Thomas & Lundh, M., 13 Jan 2015, In: Journal of Interferon & Cytokine Research. 35, 1, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes mellitus and metabolic syndrome
Ortega, E., Martín-Cordero, L., Garcia-Roves, P. M., Chicco, A. J., Gonzalez-Franquesa, A. & Marado, D., 1 Jan 2015, Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer, p. 55-79 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases
Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
Finan, B., Yang, B., Ottaway, N., Smiley, D. L., Ma, T., Clemmensen, C., Chabenne, J., Zhang, L., Habegger, K. M., Fischer, K., Campbell, J. E., Sandoval, D., Seeley, R. J., Bleicher, K., Uhles, S., Riboulet, W., Funk, J., Hertel, C., Belli, S., Sebokova, E. & 9 others, , Jan 2015, In: Nature Medicine. 21, 1, p. 27-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of moderate- and high-intensity acute exercise on appetite in obese individuals
Martins, C., Stensvold, D., Finlayson, G., Holst, Jens Juul, Wisloff, U., Kulseng, B., Morgan, L. & King, N. A., Jan 2015, In: Medicine and Science in Sports and Exercise. 47, 1, p. 40-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo
Pedersen, M. H., Bentsen, M. A., Husted, Anna Sofie, Ekberg, J. P., Wright, M. J., Di Salvo, J., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, Michael, Miller, M. W., Trujillo, M. E., Frimurer, Thomas Michael, Holst, Birgitte, Howard, A. D. & Schwartz, Thue W., Jan 2015, In: Molecular Metabolism. 4, 1, p. 3-14 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental transactions underlying the association between physical fitness/physical exercise and body composition
Johnson, W., de Ruiter, I., Kyvik, K. O., Murray, A. L. & Sørensen, Thorkild I.A., Jan 2015, In: Behavior Genetics. 45, 1, p. 84-105 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes
Christensen, Mikkel Bring, Calanna, S., wbf943, wbf943, Kristensen, P. L., Rosenkilde, Mette, Faber, Jens, Purrello, F., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Jan 2015, In: Diabetes. 64, 1, p. 72-78 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants
Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., Saxena, R., Scheer, F. A. J. L., Kovanen, L., Bartz, T. M., Perälä, M-M., Jonsson, A. E., Frazier-Wood, A. C., Kalafati, I-P., Mikkilä, V., Partonen, T. & 34 others, , Jan 2015, In: The American Journal of Clinical Nutrition. 101, 1, p. 135-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 31 others, , Jan 2015, In: P L o S Genetics. 11, 1, p. 1-25 25 p., e1004876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into the role of the microbiome in obesity and type 2 diabetes
Hartstra, A. V., Bouter, K. E. C., Bäckhed, G. F. & Nieuwdorp, M., Jan 2015, In: Diabetes Care. 38, 1, p. 159-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interplay between FGF21 and insulin action in the liver regulates metabolism
Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., Jan 2015, In: The Journal of Clinical Investigation. 125, 1, p. 458Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Prediction of adolescent and adult adiposity outcomes from early life anthropometrics
Graversen, L., Sørensen, Thorkild I.A., Gerds, Thomas Alexander, Petersen, L., Sovio, U., Kaakinen, M., Sandbaek, A., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M. & Obel, C., Jan 2015, In: Obesity. 23, 1, p. 162-169 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors
Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whey-reduced weight gain is associated with a temporary growth reduction in young mice fed a high-fat diet
Christensen, B. T., Madsen, A. N., Hansen, Axel Kornerup & Hellgren, L. I., Jan 2015, In: Journal of Nutritional Biochemistry. 26, 1, p. 9-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents
Fonvig, C. E., Chabanova, E., Andersson, E. A., Ohrt, J. D., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, 2015, In: PLOS ONE. 10, 8, 15 p., e0135018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A catalog of the mouse gut metagenome: [incl. Author Correction]
Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D., Yu, J. & 17 others, , 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comparison of isolated circulating tumor cells and tissue biopsies using whole-genome sequencing in prostate cancer
Jiang, R., Lu, Y-T., Ho, H., Li, B., Chen, J-F., Lin, M., Li, F., Wu, K., Wu, H., Lichterman, J., Wan, H., Lu, C-L., OuYang, W., Ni, M., Wang, L., Li, G., Lee, T., Zhang, X., Yang, J., Rettig, M. & 9 others, , 2015, In: OncoTarget. 6, 42, p. 44781-44793 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A glycogene mutation map for discovery of diseases of glycosylation
Hansen, Lars, Lind-Thomsen, A., Joshi, Hiren Jitendra, Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, N., Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Freeze, H. H., Hansen, Torben, Pedersen, Oluf Borbye, Henrissat, B., Mandel, Ulla, Clausen, Henrik, Wandall, Hans H. & Bennett, Eric Paul, 2015, In: Glycobiology. 25, 2, p. 211-224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity
Apuschkin, Mia, Stilling, S., Rahbek-Clemmensen, T., Sørensen, G., Fortin, G., Herborg, Freja, Eriksen, J., Trudeau, L., Egerod, Kristoffer Lihme, Gether, Ulrik & Rickhag, Karl Mattias, 2015, In: European Journal of Neuroscience. 42, 7, p. 2438-2454 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of body composition by dual-energy X-ray absorptiometry, bioimpedance analysis and anthropometrics in children: the Physical Activity and Nutrition in Children study
Tompuri, T. T., Lakka, T. A., Hakulinen, M., Lindi, V., Laaksonen, D. E., Kilpeläinen, Tuomas O., Jääskeläinen, J., Lakka, H. & Laitinen, T., 2015, In: Clinical Physiology and Functional Imaging. 35, 1, p. 21-33 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asthma in patients with psoriasis
Lønnberg, A. S., Skov, L., Skytthe, A., Kyvik, K. O., Pedersen, Oluf Borbye, Meteran, Howraman, Backer, Vibeke & Thomsen, Simon Francis, 2015, In: British Journal of Dermatology. p. 1660-1661Research output: Contribution to journal › Letter › Research › peer-review
- Published
Atmospheric Smell: hospital-based and museum-staged
Stenslund, A., 2015, SL Grafik. 216 p.Research output: Book/Report › Ph.D. thesis
- Published
Auto-inflammatory challenge of the endolymphatic sac - Cochlear damage measured by distortion product oto-acoustic emissions
Larsen, M., Friis, M., Rift, Charlotte Vestrup, Poulsen, Steen Seier, Lund, S. P. & Qvortrup, Klaus, 2015, In: Acta Oto-Laryngologica. 135, 8, p. 758-764 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors
Brighton, C. A., Rievaj, J., Kuhre, Rune Ehrenreich, Glass, L. L., Schoonjans, K., Holst, Jens Juul, Gribble, F. M. & Reimann, F., 2015, In: Endocrinology. 156, 11, p. 3961-1370 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile acid mediated effects on gut integrity and performance of early-weaned piglets
de Diego-Cabero, N., Mereu, A., Menoyo, D., Holst, Jens Juul & Ipharraguerre, I. R., 2015, In: B M C Veterinary Research. 11, 1, p. 1-8 8 p., 111.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index in school-aged children and the risk of routinely diagnosed non-alcoholic fatty liver disease in adulthood: a prospective study based on the Copenhagen School Health Records Register
Zimmermann, E., Gamborg, M., Holst, C., Baker, J. L., Sørensen, Thorkild I.A. & Berentzen, T. L., 2015, In: B M J Open. 5, p. 1-8 8 p., e006998.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers
Loft, A., Forss, I., Siersbæk, M. S., Schmidt, S. F., Larsen, A. B., Madsen, J. G. S., Pisani, D. F., Nielsen, R., Aagaard, M. M., Mathison, A., Neville, M. J., Urrutia, R., Karpe, F., Amri, E. & Mandrup, S., 2015, In: Genes & Development. 29, p. 7-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index in relation to future risk of oesophageal adenocarcinoma
Cook, M. B., Freedman, N. D., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 2015, In: B J C. 112, p. 601-607 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats
Caillaud, C., Mechta, Mie, Ainge, H., Madsen, A. N., Ruell, P., Mas, E., Bisbal, C., Mercier, J., Twigg, S., Mori, T. A., Simar, D. & Barrès, Romain, 2015, In: Journal of Endocrinology. 225, 2, p. 77-88 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian Metabolism in the Light of Evolution
Gerhart-Hines, Zach & Lazar, M. A., 2015, In: Endocrine Reviews. 36, 3, p. 289-304 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Co-Curation as Hacking: Biohackers in Copenhagen’s Medical Museion
Davies, S. R., Tybjerg, Karin, Whiteley, Louise & Söderqvist, Thomas, 2015, In: Curator: The Museum Journal. 58, 1, p. 117-131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: The Danish Conscription Database(DCD): A cohort of 728 160 men born from 1939 through 1959
Okholm, Gunhild Tidemann, Molbo, Drude, Ängquist, Lars, Mortensen, Erik Lykke, Christensen, K., Sørensen, Thorkild I.A. & Osler, Merete, 2015, In: International Journal of Epidemiology. 44, 2, p. 432-40Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study
Hollensted, M., Ahluwalia, Tarun Veer Singh, Have, C. T., Grarup, N., Fonvig, C. E., Nielsen, T. R. H., Trier, C., Paternoster, L., Pedersen, Oluf Borbye, Holm, Jens-Christian, Sørensen, Thorkild I.A. & Hansen, Torben, 2015, In: BMC Medical Genetics. 16, 9 p., 105.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction
Zhang, W., Yu, Y., Hertwig, F., Thierry-Mieg, J., Zhang, W., Thierry-Mieg, D., Wang, J., Furlanello, C., Devanarayan, V., Cheng, J., Deng, Y., Hero, B., Hong, H., Jia, M., Li, L., Lin, S. M., Nikolsky, Y., Oberthuer, A., Qing, T., Su, Z. & 56 others, , 2015, In: Genome Biology (Online Edition). 16, 12 p., 133.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of variations detection between whole-genome amplification methods used in single-cell resequencing
Hou, Y., Wu, K., Shi, X., Li, F., Song, L., Wu, H., Dean, M., Li, G., Tsang, S., Jiang, R., Zhang, X., Li, B., Liu, G., Bedekar, N., Lu, N., Xie, G., Liang, H., Chang, L., Wang, T., Chen, J. & 6 others, , 2015, In: GigaScience. 4, 16 p., 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5
Hunt, L. E., Noyvert, B., Bhaw-Rosun, L., Sesay, A. K., Paternoster, L., Nohr, E. A., Davey Smith, G., Tommerup, Niels, Sørensen, Thorkild I.A. & Elgar, G., 2015, In: Genome Medicine. 7, 1, p. 1-14 14 p., 126.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conflicts of Interest
Høj, J. B. & Whiteley, Louise, 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). Frederiksberg: Department of Food and Resource Economics, University of Copenhagen, p. 76-89Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study.
Dijkstra, A., Smolonska, J., van, D. B. M., Wijmenga, C., Zanen, P., Luinge, M., Platteel, M., Lammers, J., Dahlback, M., Tosh, K., Hiemstra, P., Sterk, P., Spira, A., Vestbo, J., Nordestgaard, Børge, Benn, Marianne, Nielsen, S., Dahl, Morten, Verschuren, W. & Picavet, H., 2015, In: P L o S Genetics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes in population isolates: lessons from Greenland
Grarup, N., Moltke, Ida, Albrechtsen, Anders & Hansen, Torben, 2015, In: The Review of Diabetic Studies. 12, 3-4, p. 320-329 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Dietary n-6 PUFA, carbohydrate: protein ratio and change in body weight and waist circumference: a follow-up study
Jakobsen, M. U., Madsen, L., Dethlefsen, C., Due, K. M., Halkjaer, J., Sørensen, Thorkild I.A., Kristiansen, Karsten & Overvad, K., 2015, In: Public Health Nutrition. 18, 07, p. 1317-1323 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary modulation of the gut microbiota - a randomised controlled trial in obese postmenopausal women
Brahe, L. K., Le Chatelier, E., Prifti, E., Pons, N., Kennedy, S., Blædel, T., Håkansson, J., Dalsgaard, T. K., Hansen, Torben, Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. D. & Larsen, L. H., 2015, In: British Journal of Nutrition. 114, 3, p. 406-417 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary protein and urinary nitrogen in relation to 6-year changes in fat mass and fat-free mass
Ankarfeldt, Mikkel Zöllner, Gottliebsen, K., Ängquist, Lars, Astrup, A., Heitmann, Berit & Sørensen, Thorkild I.A., 2015, In: International Journal of Obesity. 39, 1, p. 162-168 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance
Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, , 2015, In: Nature. 528, 7581, p. 262-266 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes
Reiband, H. K., Schmidt, S., Ranjan, A., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, 2015, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 31, 7, p. 672-9 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Dynamics and stabilization of the human gut microbiome during the first year of life
Bäckhed, G. F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., Khan, M. T., Zhang, J., Li, J., Xiao, L., Al-Aama, J., Zhang, D., Lee, Y. S., Kotowska, D. E., Colding, C. S., Tremaroli, V. & 7 others, , 2015, In: Cell Host & Microbe. 17, 5, p. 690-703 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early child care and obesity at 12 months of age in the Danish National Birth Cohort
Neelon, S. E. B., Andersen, C. S., Morgen, C. S., Kamper-Jørgensen, Mads, Oken, E., Gillman, M. W. & Sørensen, Thorkild I.A., 2015, In: International journal of obesity (2005). 39, p. 33-38 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs
Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients
Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure
Bagger, J. I., Holst, Jens Juul, Hartmann, Bolette, Andersen, B., Knop, Filip Krag & Vilsbøll, T., 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 12, p. 4541–4552 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes
Rhee, N. A., Wahlgren, C. D., Pedersen, J., Mortensen, B., Langholz, E., Wandall, E. P., Friis, S. U., Vilmann, Peter, Paulsen, S. J., Kristiansen, V. B., Jelsing, J., Dalbøge, L. S., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetologia. 58, 10, p. 2254-2258 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium
Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjørngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. V. S., Wannamethee, S. G., Lahti, J., Räikkönen, K. & 40 others, , 2015, In: Circulation: Cardiovascular Genetics. 8, p. 832-841 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes-a protocol for a randomised, double-blind, placebo-controlled study: The Lira-1 study
Dejgaard, T. F., Knop, Filip Krag, Tarnow, L., Frandsen, C. S., Hansen, T. S., Almdal, Thomas Peter, Holst, Jens Juul, Madsbad, Sten & Andersen, H. U., 2015, In: B M J Open. 5, 4, p. 1-8 8 p., e007791.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Embryo genome profiling by single-cell sequencing for preimplantation genetic diagnosis in a β-thalassemia family
Xu, Y., Chen, S., Yin, X., Shen, X., Pan, X., Chen, F., Jiang, H., Liang, Y., Wang, W., Xu, X., Wang, J., Zhang, X., Zhou, C. & Wang, J., 2015, In: Clinical Chemistry. 61, 4, p. 617-626 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity: a population-based study
Bonfils, L., Ellervik, Christina, Friedrich, N., Linneberg, Allan René, Sandholt, C. H., Jørgensen, M. E., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Allin, K. H., 2015, In: Diabetologia. 58, 3, p. 523-533 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks supplementation with Lactobacillus paracasei subsp. paracasei L. casei W8® shows modest effect on triacylglycerol in young healthy adults
Bjerg, A. T., Kristensen, M. B., Ritz, C., Stark, K. D., Holst, Jens Juul, Leser, T. D., Wellejus, A. & Astrup, A., 2015, In: Beneficial Microbes. 6, 1, p. 29-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GENETICALLY HIGH PLASMA VITAMIN C, INTAKE OF FRUIT AND VEGETABLES, AND RISK OF ISCHEMIC HEART DISEASE AND ALL-CAUSE MORTALITY: A MENDELIAN RANDOMIZATION STUDY
Kobylecki, C., Afzal, Shoaib, Smith, G. D. & Nordestgaard, Børge, 2015, In: Atherosclerosis.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
GLP-1 baseret behandling af diabetes og svær overvægt
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: BestPractice. 9, 4, p. 10-12 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women
Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass
Guimarães, M., Rodrigues, P., Pereira, S. S., Nora, M., Gonçalves, G., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Holst, Jens Juul & Monteiro, M. P., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-5 5 p., 150049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels
Hofsø, D., Birkeland, K. I., Holst, Jens Juul, Bollerslev, J., Sandbu, R., Røislien, J. & Hjelmesæth, J., 2015, In: Diabetology & Metabolic Syndrome. 7, p. 1-4 4 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying and disease activity in inflammatory bowel disease
Keller, J., Binnewies, U., Rösch, M., Holst, Jens Juul, Beglinger, C., Andresen, V. & Layer, P., 2015, In: European Journal of Clinical Investigation. 45, 12, p. 1234-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels
Van Leeuwen, E. M., Karssen, L. C., Deelen, J., Isaacs, A., Medina-Gomez, C., Mbarek, H., Kanterakis, A., Trompet, S., Postmus, I., Verweij, N., Van Enckevort, D. J., Huffman, J. E., White, C. C., Feitosa, M. F., Bartz, T. M., Manichaikul, A., Joshi, P. K., Peloso, G. M., Deelen, P., Van Dijk, F. & 105 others, , 2015, In: Nature Communications. 6, 6 p., 6065.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies of human adiposity: Zooming in on synapses.
Sandholt, C. H., Grarup, N., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: Molecular and Cellular Endocrinology. 418, Part 2, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study
Jacobsen, Ramune, Hypponen, E., Sørensen, Thorkild I.A., Vaag, Allan & Heitmann, Berit, 2015, In: PloS one. 10, 6, p. 1-11 11 p., e0128631.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling
Basse, A. L., Dixen, K., Yadav, R., Tygesen, M. P., Qvortrup, Klaus, Kristiansen, Karsten, Quistorff, B., Gupta, R., Wang, J. & Hansen, Jacob B., 2015, In: BMC Genomics. 16, 19 p., 215.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes
Bork-Jensen, J., Schéele, Camilla Charlotte Nielsen, Christophersen, D. V., Nilsson, E., Friedrichsen, M., Fernandez-Twinn, D. S., Grunnet, Louise Groth, Litman, T., Holmstrøm, K., Vind, B., Højlund, K., Beck-Nielsen, H., Wojtaszewski, Jørgen F P, Ozanne, S. E., Pedersen, Bente Klarlund, Poulsen, P. & Vaag, Allan, 2015, In: Diabetologia. 58, 2, p. 363-373 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Greenlandic Inuit show genetic signatures of diet and climate adaptation
Fumagalli, M., Moltke, Ida, Grarup, N., Racimo, F., Bjerregaard, P., Jørgensen, M. E., Korneliussen, Thorfinn Sand, Gerbault, P., Skotte, L., Linneberg, Allan René, Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E. B., Pedersen, Oluf Borbye, Hansen, T., Albrechtsen, Anders & Nielsen, Rasmus, 2015, In: Science (New York, N.Y.). 349, 6254, p. 1343-1347 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiome development along the colorectal adenoma-carcinoma sequence
Feng, Q., Liang, S., Jia, H., Stadlmayr, A., Tang, L., Lan, Z., Zhang, D., Xia, H., Xu, X., Jie, Z., Su, L., Li, X., Li, X., Li, J., Xiao, L., Huber-Schönauer, U., Niederseer, D., Xu, X., Al-Aama, J. Y., Yang, H. & 6 others, , 2015, In: Nature Communications. 6, 13 p., 6528.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HOODS: finding context-specific neighborhoods of proteins, chemicals and diseases
Palleja, A. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, p. 1-10 10 p., e1057.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HUMAN SKIN MICROORGANISMS ARE DISTRIBUTED IN BIOFILM AGGREGATES AT WOUND EDGES
Bay, Lene, Agren, M. S., Poulsen, Steen Seier, Ghathian, K. S. A., Calum, H. & Bjarnsholt, Thomas, 2015, In: Wound Repair and Regeneration. 23, 4, p. A3-A3 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, , 2015, In: B M J Open. 5, 8, p. 1-10 10 p., e008808.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet
Penke, M., Larsen, P. S., Schuster, S., Dall, M., Jensen, Benjamin Anderschou Holbech, Gorski, T., Meusel, A., Richter, S., Vienberg, S. G., Treebak, Jonas Thue, Kiess, W. & Garten, A., 2015, In: Molecular and Cellular Endocrinology. 412, p. 65-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides
Challis, B. G., Albrechtsen, Nicolai Jacob Wewer, Bansiya, V., Burling, K., Barker, P., Hartmann, Bolette, Gribble, F., O'Rahilly, S., Holst, Jens Juul & Simpson, H. L., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-7 7 p., 150105.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition
Rosenkilde Larsen, M., Morville, T., Riis Andersen, P., Kjær, K., Rasmusen, H., Holst, Jens Juul, Dela, Flemming, Westerterp, K., Sjödin, Anders Mikael & Helge, Jørn Wulff, 2015, In: American Journal of Clinical Nutrition. 102, 6, p. 1398-1405 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy
Kelstrup, L., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, Holst, Jens Juul & Damm, Peter, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1967-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inference of purifying and positive selection in three subspecies of chimpanzees (Pan troglodytes) from exome sequencing
Bataillon, T., Duan, J., Hvilsom, C., Jin, X., Li, Y., Skov, L., Glemin, S., Munch, K., Jiang, T., Qian, Y., Hobolth, A., Wang, J., Mailund, T., Siegismund, Hans Redlef & Schierup, M. H., 2015, In: Genome Biology and Evolution. 7, 4, p. 1122-1132 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory and metabolic alterations of Kager's fat pad in chronic achilles tendinopathy
Pingel, Jessica, Petersen, M. C. H., Fredberg, U., Kjær, S. G., Quistorff, B., Langberg, Henning & Hansen, Jacob B., 2015, In: P L o S One. 10, 5, 13 p., e0127811.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes
Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, Jens, Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children
Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, W. P., Carroll, W. L., Winick, N., Williams, R., Hansen, T. & 13 others, , 2015, In: Nature Communications. 6, p. 1-7 7 p., 7553.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept
Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients
Samocha-Bonet, D., Chisholm, D. J., Holst, Jens Juul & Greenfield, J. R., 2015, In: Nutrients. 7, 4, p. 2101-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide for Type 2 diabetes and obesity: a 2015 update
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: Expert Review of Cardiovascular Therapy. 13, 7, p. 753-67 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MECHANISMS IN ENDOCRINOLOGY: Gut microbiota in patients with type 2 diabetes mellitus
Allin, K. H., Nielsen, T. & Pedersen, Oluf Borbye, 2015, In: European Journal of Endocrinology. 172, 4, p. R167-R177 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Many obese individuals experience wheezing, rather than asthma: A Mendelian randomization study of 86,019 adults
Colak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, 2015, In: European Respiratory Journal.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle
Fonvig, C. E., Chabanova, E., Ohrt, J. D., Nielsen, L. A., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, 2015, In: B M C Pediatrics. 15, p. 1-9 9 p., 196.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation-Guided Unbiased Modeling of the Fat Sensor GPR119 for High-Yield Agonist Screening.
Norn, C., Pedersen, M. H., Engelstoft, M. S., Kim, S. H., Lehmann, J., Jones, R. M., Schwartz, Thue W. & Frimurer, Thomas Michael, 2015, In: Structure. 23, 12, p. 2377-2386 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No changes in serum tryptase after bariatric surgery
Skaaby, T., drb459, drb459, Thomsen, S., Knudsen, A. L., Jørgensen, Niklas Rye & Linneberg, Allan René, 2015, In: Annals of Epidemiology. 25, 10, p. 800-1 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios
Besenbacher, S., Liu, S., Gonzalez-Izarzugaza, J. M., Grove, J., Belling, K. G., Bork-Jensen, J., Huang, S., Als, T. D., Li, S., Yadav, R., Rubio García, A., Lescai, F., Demontis, D., Rao, J., Ye, W., Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R., Sun, J. & 27 others, , 2015, In: Nature Communications. 6, 9 p., 5969.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity Beige adipocytes-will they beat obesity?.
Sandholt, C. H. & Pedersen, Oluf Borbye, 2015, In: Nature Reviews Endocrinology. 11, 12, p. 694-696 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests
Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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