- 2015
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Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs
Barkholt, P., Vegge, A., Clausen, T. R., Birck, M. M., Fels, J. J., Støckel, M., Gögenur, Ismail, Eriksen, Thomas, Holst, Jens Juul, Hansen, Axel Kornerup, Thymann, Thomas, Jelsing, J., Sangild, Per Torp & Raun, K., 2015, In: Journal of Obesity and Bariatrics. 1, 1, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study
Mor, A., Antonsen, S., Kahlert, J., Holsteen, V., Jørgensen, S., Holm-Pedersen, J., Sørensen, H. T., Pedersen, Oluf Borbye & Ehrenstein, V., 2015, In: International journal of obesity (2005). 39, 10, p. 1450-1455 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to vitamin-D from fortified margarine and milk and body size at age 7 years
Jensen, C. B., Gamborg, Michael Orland, Berentzen, T. L., Sørensen, Thorkild I.A. & Heitmann, Berit, 2015, In: European Journal of Clinical Nutrition. 69, 10, p. 1169-75 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal parental separation and body weight, including development of overweight and obesity later in childhood
Hohwü, L., Zhu, J. L., Graversen, L., Li, J., Sørensen, Thorkild I.A. & Obel, C., 2015, In: PloS one. 10, 3, p. 1-10 10 p., e0119138.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner
Kjøbsted, Rasmus, Treebak, Jonas Thue, Fentz, J., Lantier, L., Viollet, B., Birk, Jesper Bratz, Schjerling, Peter, Björnholm, M., Zierath, Juleen R & Wojtaszewski, Jørgen F P, 2015, In: Diabetes. 64, 6, p. 2042-2055 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes
Väremo, L., Schéele, Camilla Charlotte Nielsen, Broholm, C., Mardinoglu, A., Kampf, C., Asplund, A., Nookaew, I., Uhlén, M., Pedersen, Bente Klarlund & Nielsen, J., 2015, In: Cell Reports. 11, 6, p. 921-33 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Public Science Communication
Whiteley, Louise, 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). Frederiksberg, p. 90-107Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
R package for Sex-of-Parent-specific Transmission Ratio Distortion
Huang, L. O., 2015Research output: Non-textual form › Computer programme › Research
- Published
RCR - A Danish textbook for courses in Responsible Conduct of Research [1. ed.]
Jensen, Karsten Klint (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), 2015, 1st edition ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 107 p.Research output: Book/Report › Book
- Published
Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes
Støy, J., Kampmann, U., Mengel, A., Magnusson, N. E., Jessen, N., Grarup, N., Rungby, Jørgen, Stødkilde-Jørgensen, H., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye & Møller, N., 2015, In: BMJ open diabetes research & care. 3, 1, p. 1-12 12 p., e000095.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance
Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resistant starch and protein intake enhances fat oxidation and feelings of fullness in lean and overweight/obese women
Gentile, C. L., Ward, E., Holst, Jens Juul, Astrup, A., Ormsbee, M. J., Connelly, S. & Arciero, P. J., 2015, In: Nutrition Journal. 14, 10 p., 113.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to 'Energy balance measurement: when something is not better than nothing'
Dhurandhar, N. V., Schoeller, D. A., Brown, A. W., Heymsfield, S. B., Thomas, D., Sørensen, Thorkild I.A., Speakman, J. R., Jeansonne, M., Allison, D. B. & Energy Balance Measurement Working Group, E. B. M. W. G., 2015, In: International Journal of Obesity. 39, 7Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686
Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., 2015, In: Diabetes. 64, 10, p. e38-9 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Rev-erbα and the circadian transcriptional regulation of metabolism.
Gerhart-Hines, Zach & Lazar, M. A., 2015, In: Diabetes, Obesity and Metabolism Online. 17, S1, p. 12-16 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission
Arora, T., Velagapudi, V., Pournaras, D. J., Welbourn, R., le Roux, C. W., Orešič, M. & Bäckhed, G. F., 2015, In: PLOS ONE. 10, 5, p. 1-10 10 p., e0126401.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe hypoglycaemia during treatment with sulphonylureas in patients with type 2 diabetes in the Capital Region of Denmark
Pilemann-Lyberg, S., Thorsteinsson, B., Snorgaard, O., Zander, M., drb459, drb459 & Røder, M. E., 2015, In: Diabetes Research and Clinical Practice. 110, 2, p. 202-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signal Transduction Inhibitors as Promising Anticancer Agents
Kumar, R., Dos Santos, C., Ahluwalia, Tarun Veer Singh & Singh, S., 2015, In: BioMed Research International. 2015, p. 1-2 2 p., 584170.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Site-specific programming of the host epithelial transcriptome by the gut microbiota
Sommer, F., Nookaew, I., Sommer, N., Fogelstrand, P. & Bäckhed, G. F., 2015, In: Genome Biology (Online Edition). 16, p. 1-15 15 p., 62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific inhibition of bile acid transport alters plasma lipids and GLP-1
Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.
Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes
Balslev-Harder, M., Appel, E. V. R., Grarup, N., Gjesing, A. M. P., Ahluwalia, Tarun Veer Singh, Jørgensen, T., Christensen, C., Brandslund, I., Linneberg, Allan René, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: PLOS ONE. 10, 3, p. 1-13 13 p., e0120890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report
Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study
Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
The gut microbiome in cardio-metabolic health
Hansen, T. H., Gøbel, R. J., Hansen, Torben & Pedersen, Oluf Borbye, 2015, In: Genome Medicine. 7, p. 1-16 16 p., 33.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiota modulates host amino acid and glutathione metabolism in mice
Mardinoglu, A., Shoaie, S., Bergentall, M., Ghaffari, P., Zhang, C., Larsson, E., Bäckhed, G. F. & Nielsen, J., 2015, In: Molecular Systems Biology. 11, 10, p. 1-15 15 p., 834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes
Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A. W., Abbott, J., Wahl, S., Tan, S-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. V. S., Bonder, M. J. & 31 others, , 2015, In: Nature Genetics. 47, 11, p. 1282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss
Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals
Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes mellitus
DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, Jens Juul, Hu, F. B., Kahn, C. R., Raz, I., Shulmann, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015, In: Nature Reviews. Disease Primers. 1, 22 p., 15019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the genetic history of the present-day greenlandic population
Moltke, Ida, Fumagalli, M., Korneliussen, Thorfinn Sand, Crawford, J. E., Bjerregaard, P., Jørgensen, M. E., Grarup, N., Gulløv, H. C., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Nielsen, Rasmus & Albrechtsen, Anders, 2015, In: American Journal of Human Genetics. 96, 1, p. 54-69 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of Antibiotics and Risk of Type 2 Diabetes: A Population-Based Case-Control Study
Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegård, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. 3633-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole exome sequencing identifies frequent somatic mutations in cell-cell adhesion genes in chinese patients with lung squamous cell carcinoma
Li, C., Gao, Z., Li, F., Li, X., Sun, Y., Wang, M., Li, D., Wang, R., Li, F., Fang, R., Pan, Y., Luo, X., He, J., Zheng, L., Xia, J., Qiu, L., He, J., Ye, T., Zhang, R., He, M. & 32 others, , 2015, In: Scientific Reports. 5, 11 p., 14237 .Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Pancreatic effects of GLP-1
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 22 Dec 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication
- Published
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
Gnad, T., Scheibler, S., von Kügelgen, I., Scheele, C., Kilić, A., Glöde, A., Hoffmann, L. S., Reverte-Salisa, L., Horn, P., Mutlu, S., El-Tayeb, A., Kranz, M., Deuther-Conrad, W., Brust, P., Lidell, M. E., Betz, M. J., Enerbäck, S., Schrader, J., Yegutkin, G. G., Müller, C. E. & 1 others, , 18 Dec 2014, In: Nature. 516, 7531, p. 395-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo
Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance
Kaalund, S. S., Venø, M. T., Bak, M., Møller, R. S., Laursen, H., Madsen, F., Broholm, H., Quistorff, B., Uldall, P., Tommerup, Niels, Kauppinen, S., Sabers, A., Fluiter, K., Møller, L. B., Nossent, Anne Yaël, Silahtaroglu, Asli, Kjems, J., Aronica, E. & Tümer, Asuman Zeynep, Dec 2014, In: Epilepsia. 55, 12, p. 2017-2027 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consumption of predefined 'Nordic' dietary items in ten European countries - an investigation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort
Roswall, N., Olsen, A., Boll, K., Christensen, J., Halkjær, J., Sørensen, T. I. A., Dahm, C. C., Overvad, K., Clavel-Chapelon, F., Boutron-Ruault, M. C., Cottet, V., Teucher, B., Kaaks, R., Boeing, H., von Ruesten, A., Trichopoulou, A., Oikonomou, E., Vasilopoulou, E., Pala, V., Sacerdote, C. & 24 others, , Dec 2014, In: Public Health Nutrition. 17, 12, p. 2650-2659 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors
Liebscher, I., Ackley, B., Araç, D., Ariestanti, D. M., Aust, G., Bae, B., Bista, B. R., Bridges, J. P., Duman, J. G., Engel, F. B., Giera, S., Goffinet, A. M., Hall, R. A., Hamann, J., Hartmann, N., Lin, H-H., Liu, M., Luo, R., Mogha, A., Monk, K. R. & 12 others, , Dec 2014, In: Annals of the New York Academy of Sciences. 1333, p. 43-64 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes
Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers
Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R., Kumari, M., Hällfors, J., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 44 others, , Dec 2014, In: P L o S Genetics. 10, 12, p. 1-6 6 p., e1004799.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119
Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice
Baquedano, E., Ruiz-Lopez, A. M., Sustarsic, E. G., Herpy, J., List, E. O., Chowen, J. A., Frago, L. M., Kopchick, J. J. & Argente, J., Dec 2014, In: Endocrinology. 155, 12, p. 4856-67 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance
van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Therapies for inter-relating diabetes and obesity - GLP-1 and obesity
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological and Pathological Impact of Blood Sampling by Retro-Bulbar Sinus Puncture and Facial Vein Phlebotomy in Laboratory Mice
Teilmann, A. C., Nygaard Madsen, A., Holst, Birgitte, Hau, Jann, Rozell, B. & Abelson, Klas, 26 Nov 2014, In: PloS one. 9, 11, p. 1-19 19 p., e113225.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo
Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomet og diabetes
Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 10 Nov 2014, In: Ugeskrift for Laeger. 176, 23, p. 2176-2179 V06140337.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans
Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of fetal and neonatal environment on beta cell function and development of diabetes
Nielsen, Jens Høiriis, Haase, T. N., Jaksch, C., Nalla, A., Søstrup, B., Nalla, A. A., Larsen, L., Rasmussen, M., Dalgaard, L. T., Gaarn, L. W., Thams, P., Kofod, H. & Billestrup, Nils, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1109-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The potential role of inhibitor of differentiation-3 in human adipose tissue remodeling and metabolic health
Svendstrup, M. & drb459, drb459, Nov 2014, In: Molecular Genetics and Metabolism. 113, 3, p. 149-154 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery
Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1
Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression
Agudelo, L. Z., Femenía, T., Orhan, F., Porsmyr-Palmertz, M., Goiny, M., Martinez-Redondo, V., Correia, J. C., Izadi, M., Bhat, M., Schuppe-Koistinen, I., Pettersson, A. T., Ferreira, D. M. S., Krook, A., Barrès, Romain, Zierath, Juleen R, Erhardt, S., Lindskog, M. & Ruas, J. L., 25 Sep 2014, In: Cell. 159, 1, p. 33-45 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does prenatal exposure to vitamin D-fortified margarine and milk alter birth weight? A societal experiment
Jensen, C. B., Berentzen, T. L., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Heitmann, B. L., 14 Sep 2014, In: British Journal of Nutrition. 112, 5, p. 785-793 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes
Nilsson, E., Jansson, P. A., Perfilyev, A., Volkov, P., Pedersen, M., Svensson, M. K., Poulsen, P., Ribel-Madsen, R., Pedersen, N. L., Almgren, P., Fadista, J., Rönn, T., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen, Vaag, Allan & Ling, C., Sep 2014, In: Diabetes. 63, 9, p. 2962-2976 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study
Vimaleswaran, K. S., Cavadino, A., Berry, D. J., Jorde, R., Dieffenbach, A. K., Lu, C., Alves, A. C., Heerspink, H. J. L., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K. A., Nolte, I. M., Houston, D. K., Ahluwalia, T. V. S., van der Most, P. J., Pasko, D., Zgaga, L., Thiering, E. & 31 others, , Sep 2014, In: The Lancet Diabetes & Endocrinology. 2, 9, p. 719-729 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human
Simar, D., Versteyhe, S., Donkin, I., Liu, J., Hesson, L., Nylander, V. C., Fossum, A. & Barrès, Romain, Sep 2014, In: Metabolism. 63, 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify variants in developmental genes associated with hypospadias
Geller, F., Feenstra, B., Carstensen, L., Pers, Tune H, van Rooij, I. A. L. M., Korberg, I. B., Choudhry, S., Karjalainen, J. M., Schnack, T. H., Hollegaard, M. V., Feitz, W. F. J., Roeleveld, N., Hougaard, D. M., Hirschhorn, J. N., Franke, L., Baskin, L. S., Nordenskjold, A., van der Zanden, L. F. M. & Melbye, M., Sep 2014, In: Nature Genetics. 46, 9, p. 957-+Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients
Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity: Global trends in the prevalence of overweight and obesity
Morgen, C. S. & Sørensen, Thorkild I.A., Sep 2014, In: Nature Reviews Endocrinology. 10, 9, p. 513-514 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial
Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract
Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of high-fat diet on rat myometrium during pregnancy-isolated myometrial mitochondria are not affected
Gam, C. M. B. F., Mortensen, Ole Hartvig, Qvortrup, Klaus, Damm, Peter & Quistorff, B., 21 Aug 2014, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1539-1549 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tarmbakterier kan have betydning for overvægt i barnealderen
Fonvig, C. E., Pihl, A. F., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 18 Aug 2014, In: Ugeskrift for Laeger. 176, p. 2-6 5 p., V03140171.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
Deelen, J., Beekman, M., Uh, H-W., Broer, L., Ayers, K. L., Tan, Q., Kamatani, Y., Bennet, A. M., Tamm, R., Trompet, S., Guðbjartsson, D. F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H. J., Crocco, P., van den Akker, E. B., Böhringer, S. & 67 others, , 15 Aug 2014, In: Human Molecular Genetics. 23, 16, p. 4420-4432 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
Qi, Q., Oskari Kilpeläinen, T., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Angquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. V. S., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, , 7 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6961-6972 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor
Zhang, C., Cooper, D. E., Grevengoed, Trisha Jean, Li, L. O., Klett, E. L., Eaton, J. M., Harris, T. E. & Coleman, R. A., 1 Aug 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 307, 3, p. E305-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environmental factors affecting the expression of type IV pilus genes as well as piliation of Thermus thermophilus
Salzer, R., Kern, T., Joos, F. & Averhoff, B., Aug 2014, In: FEMS Microbiology Letters. 357, 1, p. 56-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional body composition and related aspects in research on obesity and cachexia: report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany
Müller, M. J., Baracos, V., Bosy-Westphal, A., Dulloo, A. G., Eckel, J., Fearon, K. C. H., Hall, K. D., Pietrobelli, A., Sørensen, Thorkild I.A., Speakman, J., Trayhurn, P., Visser, M. & Heymsfield, S. B., Aug 2014, In: Obesity Reviews. 15, 8, p. 640-656 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond
Grarup, N., Sandholt, C. H., Hansen, Torben & Pedersen, Oluf Borbye, Aug 2014, In: Diabetologia. 57, 8, p. 1528-41 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals
Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility
Guigas, B., de Leeuw van Weenen, J. E., van Leeuwen, N., Simonis-Bik, A. M., van Haeften, T. W., Nijpels, G., Houwing-Duistermaat, J. J., Beekman, M., Deelen, J., Havekes, L. M., Penninx, B. W. J. H., Vogelzangs, N., van 't Riet, E., Dehghan, A., Hofman, A., Witteman, J. C., Uitterlinden, A. G., Grarup, N., Jørgensen, T., Witte, D. R. & 15 others, , Aug 2014, In: Diabetic Medicine. 31, 8, p. 1001-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Timing of motor milestones achievement and development of overweight in childhood: a study within the Danish National Birth Cohort
Morgen, C. S., Nybo Andersen, Anne-Marie, Due, P., Neelon, S. B., Gamborg, Michael Orland & Sørensen, Thorkild I.A., Aug 2014, In: Pediatric Obesity. 9, 4, p. 239-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic epigenetic responses to muscle contraction
Rasmussen, M., Zierath, Juleen R & Barrès, Romain, 19 Jul 2014, In: Drug Discovery Today. 19, 7, p. 1010-4 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Identification and characterization of human brown adipose tissue (BAT) content and metabolism in adults using [18F]-FDG PET/MR – a pilot study
Johannesen, H. H., Löfgren, J., Donkin, I., Hansen, A. E., Loft, A., Højgaard, Liselotte & Kjær, Andreas, Jul 2014, In: E J N M M I Physics. 1, Suppl 1, 3 p., A68.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
META-Life: Biotechnologies, Synthetic Biology, Alife and the Arts
Bureaud, A. (ed.), Malina, R. (ed.) & Whiteley, Louise (ed.), Jul 2014, (Leonardo).Research output: Book/Report › Book › peer-review
- Published
Mapping Substance P Binding Sites on the Neurokinin-1 Receptor Using Genetic Incorporation of a Photoreactive Amino Acid
Valentin-Hansen, L., Park, M., Huber, T., Grunbeck, A., Naganathan, S., Schwartz, Thue W. & Sakmar, T. P., 27 Jun 2014, In: The Journal of Biological Chemistry. 289, 26, p. 18045-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model
Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects
Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin secretion: direct mechanisms
Balk-Møller, E., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 12 Jun 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), p. 1-3 3 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication
- Published
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
Perry, R. J., Samuel, V. T., Petersen, K. M. F. & Shulmann, G. I., 5 Jun 2014, In: Nature. 510, p. 84-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?
Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic glucocorticoid treatment increases de novo lipogenesis in visceral adipose tissue
Vienberg, S. G. & Björnholm, M., Jun 2014, In: Acta Physiologica (Print). 211, 2, p. 257-9 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin
Paul, D. S., Grevengoed, Trisha Jean, Pascual, F., Ellis, J. M., Willis, M. S. & Coleman, R. A., Jun 2014, In: B B A - Reviews on Cancer. 1841, 6, p. 880-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease
Nielsen, Thomas Svava, Jessen, N., Jørgensen, J. O. L., Møller, N. & Lund, S., Jun 2014, In: Journal of Molecular Endocrinology. 52, 3, p. R199-R222 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation
Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Jun 2014, In: Diabetes. 63, suppl 1, p. A491 1 p., Abstract no 1915-P.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients
Gjesing, A. M. P., Hornbak, M., Allin, K. H., Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, Jun 2014, In: Diabetologia. 57, 6, p. 1173-1181 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lessons from whole-exome sequencing in MODYX families
Dusatkova, P., Fang, M., Pruhova, S., Gjesing, A. P., Cinek, O., Hansen, Torben, Pedersen, Oluf Borbye, Xu, X. & Lebl, J., Jun 2014, In: Diabetes Research and Clinical Practice. 104, 3, p. e72-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo
Mattox, T. A., Young, M. E., Rubel, C. E., Spaniel, C., Rodríguez, J. E., Grevengoed, Trisha Jean, Gautel, M., Xu, Z., Anderson, E. J. & Willis, M. S., Jun 2014, In: Journal of Bioenergetics and Biomembranes. 46, 3, p. 173-87 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals
Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes
Pietraszek, A., Gregersen, S., Pedersen, S. B., Holst, Jens Juul & Hermansen, K., 14 May 2014, In: European Journal of Clinical Nutrition. 68, p. 1022-28 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FXR is a molecular target for the effects of vertical sleeve gastrectomy
Ryan, K. K., Tremaroli, V., Clemmensen, Christoffer, Kovatcheva-Datchary, P., Myronovych, A., Karns, R., Wilson-Pérez, H. E., Sandoval, D. A., Kohli, R., Bäckhed, F. & Seeley, R. J., 8 May 2014, In: Nature. 509, 7499, p. 183-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus
Torekov, Signe Sørensen, Holst, Jens Juul & Ehlers, M. R., May 2014, In: Diabetes, Obesity and Metabolism. 16, 5, p. 451-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice
Zachariah Tom, R., Garcia-Roves, P. M., Sjögren, R. J. O., Jiang, L. Q., Holmström, M. H., Deshmukh, Atul Shahaji, Vieira, E., Chibalin, A. V., Björnholm, M. & Zierath, Juleen R, May 2014, In: Diabetes. 63, 5, p. 1560-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition
Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is it acceptable to use animals to model obese humans? a critical discussion of two arguments against the use of animals in obesity research
Lund, Thomas Bøker, Sørensen, Thorkild I.A., Olsson, I. A. S., Hansen, Axel Kornerup & Sandøe, Peter, May 2014, In: Journal of Medical Ethics. 40, 5, p. 320-324 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study
Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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