Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2015
  2. Published

    Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs

    Barkholt, P., Vegge, A., Clausen, T. R., Birck, M. M., Fels, J. J., Støckel, M., Gögenur, Ismail, Eriksen, Thomas, Holst, Jens Juul, Hansen, Axel Kornerup, Thymann, Thomas, Jelsing, J., Sangild, Per Torp & Raun, K., 2015, In: Journal of Obesity and Bariatrics. 1, 1, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study

    Mor, A., Antonsen, S., Kahlert, J., Holsteen, V., Jørgensen, S., Holm-Pedersen, J., Sørensen, H. T., Pedersen, Oluf Borbye & Ehrenstein, V., 2015, In: International journal of obesity (2005). 39, 10, p. 1450-1455 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Prenatal exposure to vitamin-D from fortified margarine and milk and body size at age 7 years

    Jensen, C. B., Gamborg, Michael Orland, Berentzen, T. L., Sørensen, Thorkild I.A. & Heitmann, Berit, 2015, In: European Journal of Clinical Nutrition. 69, 10, p. 1169-75 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Prenatal parental separation and body weight, including development of overweight and obesity later in childhood

    Hohwü, L., Zhu, J. L., Graversen, L., Li, J., Sørensen, Thorkild I.A. & Obel, C., 2015, In: PloS one. 10, 3, p. 1-10 10 p., e0119138.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner

    Kjøbsted, Rasmus, Treebak, Jonas Thue, Fentz, J., Lantier, L., Viollet, B., Birk, Jesper Bratz, Schjerling, Peter, Björnholm, M., Zierath, Juleen R & Wojtaszewski, Jørgen F P, 2015, In: Diabetes. 64, 6, p. 2042-2055 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes

    Väremo, L., Schéele, Camilla Charlotte Nielsen, Broholm, C., Mardinoglu, A., Kampf, C., Asplund, A., Nookaew, I., Uhlén, M., Pedersen, Bente Klarlund & Nielsen, J., 2015, In: Cell Reports. 11, 6, p. 921-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Public Science Communication

    Whiteley, Louise, 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). Frederiksberg, p. 90-107

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  9. Published

    R package for Sex-of-Parent-specific Transmission Ratio Distortion

    Huang, L. O., 2015

    Research output: Non-textual formComputer programmeResearch

  10. Published

    RCR - A Danish textbook for courses in Responsible Conduct of Research [1. ed.]

    Jensen, Karsten Klint (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), 2015, 1st edition ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 107 p.

    Research output: Book/ReportBook

  11. Published

    Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes

    Støy, J., Kampmann, U., Mengel, A., Magnusson, N. E., Jessen, N., Grarup, N., Rungby, Jørgen, Stødkilde-Jørgensen, H., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye & Møller, N., 2015, In: BMJ open diabetes research & care. 3, 1, p. 1-12 12 p., e000095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance

    Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Resistant starch and protein intake enhances fat oxidation and feelings of fullness in lean and overweight/obese women

    Gentile, C. L., Ward, E., Holst, Jens Juul, Astrup, A., Ormsbee, M. J., Connelly, S. & Arciero, P. J., 2015, In: Nutrition Journal. 14, 10 p., 113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Response to 'Energy balance measurement: when something is not better than nothing'

    Dhurandhar, N. V., Schoeller, D. A., Brown, A. W., Heymsfield, S. B., Thomas, D., Sørensen, Thorkild I.A., Speakman, J. R., Jeansonne, M., Allison, D. B. & Energy Balance Measurement Working Group, E. B. M. W. G., 2015, In: International Journal of Obesity. 39, 7

    Research output: Contribution to journalComment/debateResearchpeer-review

  15. Published

    Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686

    Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., 2015, In: Diabetes. 64, 10, p. e38-9 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  16. Published

    Rev-erbα and the circadian transcriptional regulation of metabolism.

    Gerhart-Hines, Zach & Lazar, M. A., 2015, In: Diabetes, Obesity and Metabolism Online. 17, S1, p. 12-16 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission

    Arora, T., Velagapudi, V., Pournaras, D. J., Welbourn, R., le Roux, C. W., Orešič, M. & Bäckhed, G. F., 2015, In: PLOS ONE. 10, 5, p. 1-10 10 p., e0126401.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Severe hypoglycaemia during treatment with sulphonylureas in patients with type 2 diabetes in the Capital Region of Denmark

    Pilemann-Lyberg, S., Thorsteinsson, B., Snorgaard, O., Zander, M., drb459, drb459 & Røder, M. E., 2015, In: Diabetes Research and Clinical Practice. 110, 2, p. 202-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Signal Transduction Inhibitors as Promising Anticancer Agents

    Kumar, R., Dos Santos, C., Ahluwalia, Tarun Veer Singh & Singh, S., 2015, In: BioMed Research International. 2015, p. 1-2 2 p., 584170.

    Research output: Contribution to journalEditorialResearchpeer-review

  20. Published

    Site-specific programming of the host epithelial transcriptome by the gut microbiota

    Sommer, F., Nookaew, I., Sommer, N., Fogelstrand, P. & Bäckhed, G. F., 2015, In: Genome Biology (Online Edition). 16, p. 1-15 15 p., 62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Specific inhibition of bile acid transport alters plasma lipids and GLP-1

    Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.

    Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes

    Balslev-Harder, M., Appel, E. V. R., Grarup, N., Gjesing, A. M. P., Ahluwalia, Tarun Veer Singh, Jørgensen, T., Christensen, C., Brandslund, I., Linneberg, Allan René, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: PLOS ONE. 10, 3, p. 1-13 13 p., e0120890.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report

    Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study

    Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  26. Published

    The gut microbiome in cardio-metabolic health

    Hansen, T. H., Gøbel, R. J., Hansen, Torben & Pedersen, Oluf Borbye, 2015, In: Genome Medicine. 7, p. 1-16 16 p., 33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The gut microbiota modulates host amino acid and glutathione metabolism in mice

    Mardinoglu, A., Shoaie, S., Bergentall, M., Ghaffari, P., Zhang, C., Larsson, E., Bäckhed, G. F. & Nielsen, J., 2015, In: Molecular Systems Biology. 11, 10, p. 1-15 15 p., 834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes

    Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

    Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A. W., Abbott, J., Wahl, S., Tan, S-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. V. S., Bonder, M. J. & 31 others, Chen, P., Dehghan, A., Edwards, T. L., Esko, T., Go, M. J., Harris, S. E., Hartiala, J., Kasela, S., Kasturiratne, A., Khor, C., Kleber, M. E., Li, H., Mok, Z. Y., Nakatochi, M., Sapari, N. S., Saxena, R., Stewart, A. F. R., Stolk, L., Tabara, Y., Teh, A. L., Wu, Y., Wu, J., Grarup, N., Justesen, Johanne Marie, Sparsø, T. H., Hansen, Torben, Jørgensen, T., Linneberg, Allan René, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & BIOS Consortium, B. C., 2015, In: Nature Genetics. 47, 11, p. 1282-93 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss

    Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals

    Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Type 2 diabetes mellitus

    DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, Jens Juul, Hu, F. B., Kahn, C. R., Raz, I., Shulmann, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015, In: Nature Reviews. Disease Primers. 1, 22 p., 15019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Uncovering the genetic history of the present-day greenlandic population

    Moltke, Ida, Fumagalli, M., Korneliussen, Thorfinn Sand, Crawford, J. E., Bjerregaard, P., Jørgensen, M. E., Grarup, N., Gulløv, H. C., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Nielsen, Rasmus & Albrechtsen, Anders, 2015, In: American Journal of Human Genetics. 96, 1, p. 54-69 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Use of Antibiotics and Risk of Type 2 Diabetes: A Population-Based Case-Control Study

    Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegård, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. 3633-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Whole exome sequencing identifies frequent somatic mutations in cell-cell adhesion genes in chinese patients with lung squamous cell carcinoma

    Li, C., Gao, Z., Li, F., Li, X., Sun, Y., Wang, M., Li, D., Wang, R., Li, F., Fang, R., Pan, Y., Luo, X., He, J., Zheng, L., Xia, J., Qiu, L., He, J., Ye, T., Zhang, R., He, M. & 32 others, Zhu, M., Hu, H., Shi, T., Zhou, X., Sun, M., Tian, S., Zhou, Y., Wang, Q., Chen, L., Yin, G., Lu, J., Wu, R., Guo, G., Li, Y., Hu, X., Li, L., Asan, Wang, Q., Yin, Y., Feng, Q., Wang, B., Wang, H., Wang, M., Yang, X., Zhang, X., Yang, H., Jin, L., Wang, C., Ji, H., Chen, H., Wang, J. & Wei, Q., 2015, In: Scientific Reports. 5, 11 p., 14237 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2014
  37. Published

    Pancreatic effects of GLP-1

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 22 Dec 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

  38. Published

    Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

    Gnad, T., Scheibler, S., von Kügelgen, I., Scheele, C., Kilić, A., Glöde, A., Hoffmann, L. S., Reverte-Salisa, L., Horn, P., Mutlu, S., El-Tayeb, A., Kranz, M., Deuther-Conrad, W., Brust, P., Lidell, M. E., Betz, M. J., Enerbäck, S., Schrader, J., Yegutkin, G. G., Müller, C. E. & 1 others, Pfeifer, A., 18 Dec 2014, In: Nature. 516, 7531, p. 395-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

    Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance

    Kaalund, S. S., Venø, M. T., Bak, M., Møller, R. S., Laursen, H., Madsen, F., Broholm, H., Quistorff, B., Uldall, P., Tommerup, Niels, Kauppinen, S., Sabers, A., Fluiter, K., Møller, L. B., Nossent, Anne Yaël, Silahtaroglu, Asli, Kjems, J., Aronica, E. & Tümer, Asuman Zeynep, Dec 2014, In: Epilepsia. 55, 12, p. 2017-2027 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Consumption of predefined 'Nordic' dietary items in ten European countries - an investigation in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

    Roswall, N., Olsen, A., Boll, K., Christensen, J., Halkjær, J., Sørensen, T. I. A., Dahm, C. C., Overvad, K., Clavel-Chapelon, F., Boutron-Ruault, M. C., Cottet, V., Teucher, B., Kaaks, R., Boeing, H., von Ruesten, A., Trichopoulou, A., Oikonomou, E., Vasilopoulou, E., Pala, V., Sacerdote, C. & 24 others, Mattiello, A., Masala, G., Peeters, P. H. M., Bueno-de-Mesquita, H. B., Engeset, D., Skeie, G., Asli, L. A., Amiano, P., Jakszyn, P., Ardanaz, E., Huerta, J. M., Quirós, J. R., Molina-Montes, E., Nilsson, L. M., Johansson, I., Wirfält, E., Drake, I., Mulligan, A. A., Khaw, K. T., Romaguera, D., Vergnaud, A., Key, T., Riboli, E. & Tjønneland, Anne, Dec 2014, In: Public Health Nutrition. 17, 12, p. 2650-2659 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors

    Liebscher, I., Ackley, B., Araç, D., Ariestanti, D. M., Aust, G., Bae, B., Bista, B. R., Bridges, J. P., Duman, J. G., Engel, F. B., Giera, S., Goffinet, A. M., Hall, R. A., Hamann, J., Hartmann, N., Lin, H-H., Liu, M., Luo, R., Mogha, A., Monk, K. R. & 12 others, Cornelia Peeters, M., Prömel, S., Ressl, S., Schiöth, H. B., Sigoillot, S. M., Song, H., Talbot, W. S., Tall, G. G., White, J. P., Wolfrum, U., Xu, L. & Piao, X., Dec 2014, In: Annals of the New York Academy of Sciences. 1333, p. 43-64 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes

    Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers

    Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R., Kumari, M., Hällfors, J., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 44 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., Kisialiou, A., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Frayling, T., Nohr, E. A., Christiansen, L., Ohm Kyvik, K., Kuh, D., Watt, G., Eriksson, J., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, Allan René, Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, Thorkild I.A., Munafò, M. R. & Sattar, N., Dec 2014, In: P L o S Genetics. 10, 12, p. 1-6 6 p., e1004799.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119

    Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice

    Baquedano, E., Ruiz-Lopez, A. M., Sustarsic, E. G., Herpy, J., List, E. O., Chowen, J. A., Frago, L. M., Kopchick, J. J. & Argente, J., Dec 2014, In: Endocrinology. 155, 12, p. 4856-67 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  48. Published

    Therapies for inter-relating diabetes and obesity - GLP-1 and obesity

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Physiological and Pathological Impact of Blood Sampling by Retro-Bulbar Sinus Puncture and Facial Vein Phlebotomy in Laboratory Mice

    Teilmann, A. C., Nygaard Madsen, A., Holst, Birgitte, Hau, Jann, Rozell, B. & Abelson, Klas, 26 Nov 2014, In: PloS one. 9, 11, p. 1-19 19 p., e113225.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo

    Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Genomet og diabetes

    Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 10 Nov 2014, In: Ugeskrift for Laeger. 176, 23, p. 2176-2179 V06140337.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans

    Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Impact of fetal and neonatal environment on beta cell function and development of diabetes

    Nielsen, Jens Høiriis, Haase, T. N., Jaksch, C., Nalla, A., Søstrup, B., Nalla, A. A., Larsen, L., Rasmussen, M., Dalgaard, L. T., Gaarn, L. W., Thams, P., Kofod, H. & Billestrup, Nils, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1109-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The potential role of inhibitor of differentiation-3 in human adipose tissue remodeling and metabolic health

    Svendstrup, M. & drb459, drb459, Nov 2014, In: Molecular Genetics and Metabolism. 113, 3, p. 149-154 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery

    Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

    Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression

    Agudelo, L. Z., Femenía, T., Orhan, F., Porsmyr-Palmertz, M., Goiny, M., Martinez-Redondo, V., Correia, J. C., Izadi, M., Bhat, M., Schuppe-Koistinen, I., Pettersson, A. T., Ferreira, D. M. S., Krook, A., Barrès, Romain, Zierath, Juleen R, Erhardt, S., Lindskog, M. & Ruas, J. L., 25 Sep 2014, In: Cell. 159, 1, p. 33-45 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Does prenatal exposure to vitamin D-fortified margarine and milk alter birth weight? A societal experiment

    Jensen, C. B., Berentzen, T. L., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Heitmann, B. L., 14 Sep 2014, In: British Journal of Nutrition. 112, 5, p. 785-793 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes

    Nilsson, E., Jansson, P. A., Perfilyev, A., Volkov, P., Pedersen, M., Svensson, M. K., Poulsen, P., Ribel-Madsen, R., Pedersen, N. L., Almgren, P., Fadista, J., Rönn, T., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen, Vaag, Allan & Ling, C., Sep 2014, In: Diabetes. 63, 9, p. 2962-2976 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

    Vimaleswaran, K. S., Cavadino, A., Berry, D. J., Jorde, R., Dieffenbach, A. K., Lu, C., Alves, A. C., Heerspink, H. J. L., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K. A., Nolte, I. M., Houston, D. K., Ahluwalia, T. V. S., van der Most, P. J., Pasko, D., Zgaga, L., Thiering, E. & 31 others, Vitart, V., Fraser, R. M., Huffman, J. E., de Boer, R. A., Schöttker, B., Saum, K., McCarthy, M. I., Dupuis, J., Herzig, K., Sebert, S., Pouta, A., Laitinen, J., Kleber, M. E., Navis, G., Lorentzon, M., Jameson, K., Arden, N., Cooper, J. A., Acharya, J., Hardy, R., Raitakari, O., Ripatti, S., Billings, L. K., Lahti, J., Osmond, C., Penninx, B. W., Rejnmark, L., Lohman, K. K., Paternoster, L., Sørensen, Thorkild I.A. & LifeLines Cohort Study investigators, L. C. S. I., Sep 2014, In: The Lancet Diabetes & Endocrinology. 2, 9, p. 719-729 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    DNA methylation is altered in B and NK lymphocytes in obese and type 2 diabetic human

    Simar, D., Versteyhe, S., Donkin, I., Liu, J., Hesson, L., Nylander, V. C., Fossum, A. & Barrès, Romain, Sep 2014, In: Metabolism. 63, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Genome-wide association analyses identify variants in developmental genes associated with hypospadias

    Geller, F., Feenstra, B., Carstensen, L., Pers, Tune H, van Rooij, I. A. L. M., Korberg, I. B., Choudhry, S., Karjalainen, J. M., Schnack, T. H., Hollegaard, M. V., Feitz, W. F. J., Roeleveld, N., Hougaard, D. M., Hirschhorn, J. N., Franke, L., Baskin, L. S., Nordenskjold, A., van der Zanden, L. F. M. & Melbye, M., Sep 2014, In: Nature Genetics. 46, 9, p. 957-+

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients

    Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Obesity: Global trends in the prevalence of overweight and obesity

    Morgen, C. S. & Sørensen, Thorkild I.A., Sep 2014, In: Nature Reviews Endocrinology. 10, 9, p. 513-514 2 p.

    Research output: Contribution to journalComment/debateResearch

  65. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial

    Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  66. Published

    The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract

    Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Effect of high-fat diet on rat myometrium during pregnancy-isolated myometrial mitochondria are not affected

    Gam, C. M. B. F., Mortensen, Ole Hartvig, Qvortrup, Klaus, Damm, Peter & Quistorff, B., 21 Aug 2014, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1539-1549 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Tarmbakterier kan have betydning for overvægt i barnealderen

    Fonvig, C. E., Pihl, A. F., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 18 Aug 2014, In: Ugeskrift for Laeger. 176, p. 2-6 5 p., V03140171.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

    Deelen, J., Beekman, M., Uh, H-W., Broer, L., Ayers, K. L., Tan, Q., Kamatani, Y., Bennet, A. M., Tamm, R., Trompet, S., Guðbjartsson, D. F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H. J., Crocco, P., van den Akker, E. B., Böhringer, S. & 67 others, Helmer, Q., Nelson, C. P., Saunders, G. I., Alver, M., Andersen-Ranberg, K., Breen, M. E., van der Breggen, R., Caliebe, A., Capri, M., Cevenini, E., Collerton, J. C., Dato, S., Davies, K., Ford, I., Gampe, J., Garagnani, P., de Geus, E. J. C., Harrow, J., van Heemst, D., Heijmans, B. T., Heinsen, F., Hottenga, J., Hofman, A., Jeune, B., Jonsson, P. V., Lathrop, M., Lechner, D., Martin-Ruiz, C., Mcnerlan, S. E., Mihailov, E., Montesanto, A., Mooijaart, S. P., Murphy, A., Nohr, E. A., Paternoster, L., Postmus, I., Rivadeneira, F., Ross, O. A., Salvioli, S., Sattar, N., Schreiber, S., Stefánsson, H., Stott, D. J., Tiemeier, H., Uitterlinden, A. G., Westendorp, R. G. J., Willemsen, G., Samani, N. J., Galan, P., Sørensen, Thorkild I.A., Boomsma, D. I., Jukema, J. W., Rea, I. M., Passarino, G., de Craen, A. J. M., Christensen, K., Nebel, A., Stefánsson, K., Metspalu, A., Magnusson, P., Blanché, H., Christiansen, L., Kirkwood, T. B. L., van Duijn, C. M., Franceschi, C., Houwing-Duistermaat, J. J. & Slagboom, P. E., 15 Aug 2014, In: Human Molecular Genetics. 23, 16, p. 4420-4432 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

    Qi, Q., Oskari Kilpeläinen, T., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Angquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. V. S., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, Eriksson, J., Perola, M., Friedlander, Y., Gao, Y., Heppe, D. H. M., Holloway, J. W., Houston, D. K., Kanoni, S., Kim, Y., Laaksonen, M. A., Jääskeläinen, T., Lee, N. R., Lehtimäki, T., Lemaitre, R. N., Lu, W., Luben, R. N., Manichaikul, A., Männistö, S., Marques-Vidal, P., Monda, K. L., Ngwa, J. S., Perusse, L., van Rooij, F. J. A., Xiang, Y., Wen, W., Wojczynski, M. K., Zhu, J., Borecki, I. B., Bouchard, C., Cai, Q., Cooper, C., Dedoussis, G. V., Deloukas, P., Ferrucci, L., Forouhi, N. G., Hansen, Torben, Christiansen, L., Hofman, A., Johansson, I., Jørgensen, T., Karasawa, S., Khaw, K., Kim, M., Kristiansson, K., Li, H., Lin, X., Liu, Y., Lohman, K. K., Long, J., Mikkilä, V., Mozaffarian, D., North, K., Pedersen, Oluf Borbye, Raitakari, O., Rissanen, H., Tuomilehto, J., van der Schouw, Y. T., Uitterlinden, A. G., Carola Zillikens, M., Franco, O. H., Shyong Tai, E., Ou Shu, X., Siscovick, D. S., Toft, Ulla Marie Nørgaard, Monique Verschuren, W. M., Vollenweider, P., Wareham, N. J., Witteman, J. C. M., Zheng, W., Ridker, P. M., Kang, J. H., Liang, L., Jensen, M. K., Curhan, G. C., Pasquale, L. R., Hunter, D. J., Mohlke, K. L., Uusitupa, M., Adrienne Cupples, L., Rankinen, T., Orho-Melander, M., Wang, T., Chasman, D. I., Franks, P. W., Sørensen, Thorkild I.A., Hu, F. B., Loos, R. J. F., Nettleton, J. A. & Qi, L., 7 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6961-6972 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

    Zhang, C., Cooper, D. E., Grevengoed, Trisha Jean, Li, L. O., Klett, E. L., Eaton, J. M., Harris, T. E. & Coleman, R. A., 1 Aug 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 307, 3, p. E305-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Environmental factors affecting the expression of type IV pilus genes as well as piliation of Thermus thermophilus

    Salzer, R., Kern, T., Joos, F. & Averhoff, B., Aug 2014, In: FEMS Microbiology Letters. 357, 1, p. 56-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Functional body composition and related aspects in research on obesity and cachexia: report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany

    Müller, M. J., Baracos, V., Bosy-Westphal, A., Dulloo, A. G., Eckel, J., Fearon, K. C. H., Hall, K. D., Pietrobelli, A., Sørensen, Thorkild I.A., Speakman, J., Trayhurn, P., Visser, M. & Heymsfield, S. B., Aug 2014, In: Obesity Reviews. 15, 8, p. 640-656 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  74. Published

    Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

    Grarup, N., Sandholt, C. H., Hansen, Torben & Pedersen, Oluf Borbye, Aug 2014, In: Diabetologia. 57, 8, p. 1528-41 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  75. Published

    High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals

    Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility

    Guigas, B., de Leeuw van Weenen, J. E., van Leeuwen, N., Simonis-Bik, A. M., van Haeften, T. W., Nijpels, G., Houwing-Duistermaat, J. J., Beekman, M., Deelen, J., Havekes, L. M., Penninx, B. W. J. H., Vogelzangs, N., van 't Riet, E., Dehghan, A., Hofman, A., Witteman, J. C., Uitterlinden, A. G., Grarup, N., Jørgensen, T., Witte, D. R. & 15 others, Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Hottenga, J., Romijn, J. A., Diamant, M., Kramer, M. H. H., Heine, R. J., Willemsen, G., Dekker, J. M., Eekhoff, E. M., Pijl, H., de Geus, E. J., Slagboom, P. E. & 't Hart, L. M., Aug 2014, In: Diabetic Medicine. 31, 8, p. 1001-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Timing of motor milestones achievement and development of overweight in childhood: a study within the Danish National Birth Cohort

    Morgen, C. S., Nybo Andersen, Anne-Marie, Due, P., Neelon, S. B., Gamborg, Michael Orland & Sørensen, Thorkild I.A., Aug 2014, In: Pediatric Obesity. 9, 4, p. 239-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Dynamic epigenetic responses to muscle contraction

    Rasmussen, M., Zierath, Juleen R & Barrès, Romain, 19 Jul 2014, In: Drug Discovery Today. 19, 7, p. 1010-4 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  79. Published

    Identification and characterization of human brown adipose tissue (BAT) content and metabolism in adults using [18F]-FDG PET/MR – a pilot study

    Johannesen, H. H., Löfgren, J., Donkin, I., Hansen, A. E., Loft, A., Højgaard, Liselotte & Kjær, Andreas, Jul 2014, In: E J N M M I Physics. 1, Suppl 1, 3 p., A68.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  80. Published

    META-Life: Biotechnologies, Synthetic Biology, Alife and the Arts

    Bureaud, A. (ed.), Malina, R. (ed.) & Whiteley, Louise (ed.), Jul 2014, (Leonardo).

    Research output: Book/ReportBookpeer-review

  81. Published

    Mapping Substance P Binding Sites on the Neurokinin-1 Receptor Using Genetic Incorporation of a Photoreactive Amino Acid

    Valentin-Hansen, L., Park, M., Huber, T., Grunbeck, A., Naganathan, S., Schwartz, Thue W. & Sakmar, T. P., 27 Jun 2014, In: The Journal of Biological Chemistry. 289, 26, p. 18045-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model

    Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Incretin secretion: direct mechanisms

    Balk-Møller, E., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 12 Jun 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), p. 1-3 3 p.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

  86. Published

    The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

    Perry, R. J., Samuel, V. T., Petersen, K. M. F. & Shulmann, G. I., 5 Jun 2014, In: Nature. 510, p. 84-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Chronic glucocorticoid treatment increases de novo lipogenesis in visceral adipose tissue

    Vienberg, S. G. & Björnholm, M., Jun 2014, In: Acta Physiologica (Print). 211, 2, p. 257-9 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  89. Published

    Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin

    Paul, D. S., Grevengoed, Trisha Jean, Pascual, F., Ellis, J. M., Willis, M. S. & Coleman, R. A., Jun 2014, In: B B A - Reviews on Cancer. 1841, 6, p. 880-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

    Nielsen, Thomas Svava, Jessen, N., Jørgensen, J. O. L., Møller, N. & Lund, S., Jun 2014, In: Journal of Molecular Endocrinology. 52, 3, p. R199-R222 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  91. Published

    Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Jun 2014, In: Diabetes. 63, suppl 1, p. A491 1 p., Abstract no 1915-P.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  92. Published

    High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients

    Gjesing, A. M. P., Hornbak, M., Allin, K. H., Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, Jun 2014, In: Diabetologia. 57, 6, p. 1173-1181 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Lessons from whole-exome sequencing in MODYX families

    Dusatkova, P., Fang, M., Pruhova, S., Gjesing, A. P., Cinek, O., Hansen, Torben, Pedersen, Oluf Borbye, Xu, X. & Lebl, J., Jun 2014, In: Diabetes Research and Clinical Practice. 104, 3, p. e72-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo

    Mattox, T. A., Young, M. E., Rubel, C. E., Spaniel, C., Rodríguez, J. E., Grevengoed, Trisha Jean, Gautel, M., Xu, Z., Anderson, E. J. & Willis, M. S., Jun 2014, In: Journal of Bioenergetics and Biomembranes. 46, 3, p. 173-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes

    Pietraszek, A., Gregersen, S., Pedersen, S. B., Holst, Jens Juul & Hermansen, K., 14 May 2014, In: European Journal of Clinical Nutrition. 68, p. 1022-28 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    FXR is a molecular target for the effects of vertical sleeve gastrectomy

    Ryan, K. K., Tremaroli, V., Clemmensen, Christoffer, Kovatcheva-Datchary, P., Myronovych, A., Karns, R., Wilson-Pérez, H. E., Sandoval, D. A., Kohli, R., Bäckhed, F. & Seeley, R. J., 8 May 2014, In: Nature. 509, 7499, p. 183-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus

    Torekov, Signe Sørensen, Holst, Jens Juul & Ehlers, M. R., May 2014, In: Diabetes, Obesity and Metabolism. 16, 5, p. 451-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice

    Zachariah Tom, R., Garcia-Roves, P. M., Sjögren, R. J. O., Jiang, L. Q., Holmström, M. H., Deshmukh, Atul Shahaji, Vieira, E., Chibalin, A. V., Björnholm, M. & Zierath, Juleen R, May 2014, In: Diabetes. 63, 5, p. 1560-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition

    Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Is it acceptable to use animals to model obese humans? a critical discussion of two arguments against the use of animals in obesity research

    Lund, Thomas Bøker, Sørensen, Thorkild I.A., Olsson, I. A. S., Hansen, Axel Kornerup & Sandøe, Peter, May 2014, In: Journal of Medical Ethics. 40, 5, p. 320-324 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study

    Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review