- 2014
- Published
Quality control and conduct of genome-wide association meta-analyses
Winkler, T. W., Day, F. R., Croteau-Chonka, D. C., Wood, A. R., Locke, A. E., Mägi, R., Ferreira, T., Fall, T., Graff, M., Justice, A. E., Luan, J., Gustafsson, S., Randall, J. C., Vedantam, S., Workalemahu, T., Kilpeläinen, T., Scherag, A., Esko, T., Kutalik, Z., Heid, I. M. & 2 others, , May 2014, In: Nature Protocols (Online). 9, 5, p. 1192-1212 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of growth hormone (GH) action in mice: Discovery of GH receptor antagonists and clinical indications
Kopchick, J. J., List, E. O., Kelder, B., Gosney, E. S. & Berryman, D. E., 5 Apr 2014, In: Molecular and Cellular Endocrinology. 386, 1-2, p. 34-45 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes
Harder-Lauridsen, N. M., Krogh-Madsen, Rikke, Holst, Jens Juul, Plomgaard, P., Leick, L., Pedersen, Bente Klarlund & Fischer, C. P., 1 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 7, p. E769-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans
Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Probabilistic Genome-Wide Gene Reading Frame Sequence Model
Have, C. T. & Mørk, S., Apr 2014. 12 p.Research output: Contribution to conference › Paper › Research › peer-review
- Published
A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk
Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet
Clemmensen, Christoffer, Chabenne, J., Finan, B., Sullivan, L., Fischer, K., Küchler, D., Sehrer, L., Ograjsek, T., Hofmann, S. M., Schriever, S. C., Pfluger, P. T., Pinkstaff, J., Tschöp, M. H., Dimarchi, R. & Müller, T. D., Apr 2014, In: Diabetes. 63, 4, p. 1422-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity
Vrieze, A., Out, C., Fuentes, S., Jonker, L., Reuling, I., Kootte, R. S., van Nood, E., Holleman, F., Knaapen, M., Romijn, J. A., Soeters, M. R., Blaak, E. E., Dallinga-Thie, G. M., Reijnders, D., Ackermans, M. T., Serlie, M. J., Knop, F. K., Holst, J. J., van der Ley, C., Kema, I. P. & 6 others, , Apr 2014, In: Journal of Hepatology. 60, 4, p. 824-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference
Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, Berit & Sørensen, Thorkild I.A., Apr 2014, In: The American Journal of Clinical Nutrition. 99, 4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia
Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of melanocortin-4 receptor function attenuates HPA responses to psychological stress
Ryan, K. K., Mul, J. D., Clemmensen, Christoffer, Egan, A. E., Begg, D. P., Halcomb, K., Seeley, R. J., Herman, J. P. & Ulrich-Lai, Y. M., Apr 2014, In: Psychoneuroendocrinology. 42, p. 98-105 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 31 others, , Apr 2014, In: Nature Genetics. 46, 4, p. 357-63 7 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Pleiotropic effects of HNF1A rs1183910 in a population-based study of 60,283 individuals
Allin, K. H. & Nordestgaard, Børge, Apr 2014, In: Diabetologia. 57, 4, p. 729-737 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased metabolic flexibility and complexity in a long-lived growth hormone insensitive mouse model
Lee Hong, S., Longo, K. A., Gosney, E. & Kopchick, J. J., 17 Mar 2014, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 69 A, 3, p. 274-281 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8
Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose triglyceride lipase and g0/g1 switch gene 2: approaching proof of concept
Nielsen, Thomas Svava & Møller, N., Mar 2014, In: Diabetes. 63, 3, p. 847-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birth weight, childhood BMI and height in relation to mammographic density and breast cancer: Register based cohort study
Andersen, Zorana Jovanovic, Baker, J. L., Bihrmann, K., Vejborg, I., Sørensen, Thorkild I.A. & Lynge, Elsebeth, Mar 2014, In: European Journal of Cancer. 50, Suppl S2, p. S75-S75 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade
Aulinger, B. A., Bedorf, A., Kutscherauer, G., de Heer, J., Holst, Jens Juul, Göke, B. & Schirra, J., Mar 2014, In: Diabetes. 63, 3, p. 1079-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gating function of isoleucine-116 in TM-3 (position III:16/3.40) for the activity state of the CC-chemokine receptor 5 (CCR5)
Steen, A., wbf943, wbf943, Thiele, S., Guo, D., Frimurer, Thomas Michael & Rosenkilde, Mette, Mar 2014, In: British Journal of Pharmacology. 171, 6, p. 1566-79 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S., Almgren, P., Atalay, M., Aung, T., Baldassarre, D., Balkau, B. & 31 others, , Mar 2014, In: Nature Genetics. 46, 3, p. 234-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes
Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance alters islet morphology in nondiabetic humans
Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin effect does not differ in trained and untrained, young, healthy men
Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in genes related to hepatic lipid metabolism and changes in waist circumference and body weight
Meidtner, K., Fisher, E., Ängquist, Lars, Holst, C., Vimaleswaran, K. S., Boer, J. M. A., Halkjær, J., Masala, G., Ostergaard, J. N., Mortensen, L. M., van der A, D. L., Tjønneland, A., Palli, D., Overvad, K., Wareham, N. J., Loos, R. J. F., Sørensen, Thorkild I.A. & Boeing, H., Mar 2014, In: Genes & Nutrition. 9, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding
Jacobsen, S. C., Gillberg, L., Bork-Jensen, J., Ribel-Madsen, R., Lara, E., Calvanese, V., Ling, C., Fernandez, A. F., Fraga, M. F., Poulsen, P., Brøns, C. & Vaag, Allan, 26 Feb 2014, In: Diabetologia. 57, 6, p. 1154-1158 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interplay between FGF21 and insulin action in the liver regulates metabolism
Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., 3 Feb 2014, In: The Journal of Clinical Investigation. 124, 2, p. 515-27 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index in childhood and adult risk of primary liver cancer
Berentzen, T. L., Gamborg, Michael Orland, Holst, C., Sørensen, Thorkild I.A. & Baker, J. L., Feb 2014, In: Journal of Hepatology. 60, 2, p. 325-30 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose
Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation of L cells in mouse and human small intestine organoids
Petersen, N., Reimann, F., Bartfeld, S., Farin, H. F., Ringnalda, F. C., Vries, R. G. J., van den Brink, S., Clevers, H., Gribble, F. M. & de Koning, E. J. P., Feb 2014, In: Diabetes. 63, 2, p. 410-20 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and familial environmental effects on suicide attempts: A study of Danish adoptees and their biological and adoptive siblings
Petersen, L., Sørensen, Thorkild I.A., Andersen, Per Kragh, Mortensen, P. B. & Hawton, K., Feb 2014, In: Journal of Affective Disorders. 155, p. 273-277 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How do pregnancy-related weight changes and breastfeeding relate to maternal weight and BMI-adjusted waist circumference 7 y after delivery? Results from a path analysis
Kirkegaard, H., Stovring, H., Rasmussen, K. M., Abrams, B., Sørensen, Thorkild I.A. & Nohr, E. A., Feb 2014, In: The American Journal of Clinical Nutrition. 99, 2, p. 312-319 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: a prospective randomized study
Tamandl, D., Sahora, K., Prucker, J., Schmid, R., Holst, J., Miholic, J., Goetzinger, P., Gnant, M. & Holst, Jens Juul, Feb 2014, In: World Journal of Surgery. 38, 2, p. 465-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery
Madsbad, Sten, Dirksen, C. & Holst, Jens Juul, Feb 2014, In: The Lancet Diabetes & Endocrinology. 2, 2, p. 152-64 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of referral for cardiac rehabilitation on survival following acute myocardial infarction: a comparison survival in two cohorts collected in 1995 and 2003
Lewinter, C., Bland, J. M., Crouch, S., Doherty, P., Lewin, R. J., Køber, Lars Valeur, Hall, A. S. & Gale, C. P., Feb 2014, In: European Journal of Preventive Cardiology. 21, 2, p. 163-171 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass
Kirchner, H., Nylen, C., Laber, S., Barrès, Romain, Yan, J., Krook, A., Zierath, Juleen R & Näslund, E., 28 Jan 2014, In: Surgery for Obesity and Related Diseases. 10, 4, p. 671-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
Steinthorsdottir, V., Thorleifsson, G., Sulem, P., Helgason, H., Grarup, N., Sigurdsson, A., Helgadottir, H. T., Johannsdottir, H., Magnusson, O. T., Gudjonsson, S. A., Justesen, J. M., Harder, M. N., Jørgensen, M. E., Christensen, C., Brandslund, I., Sandbæk, A., Lauritzen, T., Vestergaard, H., Linneberg, A., Jørgensen, T. & 14 others, , 26 Jan 2014, In: Nature Genetics. 46, 3, p. 294-300 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification
Husemoen, L. L. N., Skaaby, T., Jørgensen, T., Thuesen, B. H., Fenger, M., Grarup, N., Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Jan 2014, In: European Journal of Nutrition. 53, 7, p. 1549-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle specific miRNAs are induced by testosterone and independently upregulated by age
Nielsen, S., Hvid, T., Kelly, M., Lindegaard, B., Dethlefsen, C., Winding, K., Mathur, N., Schéele, Camilla Charlotte Nielsen, Pedersen, Bente Klarlund & Laye, M. J., 23 Jan 2014, In: Frontiers in Physiology. 4, p. 1-11 11 p., 394.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs
Sigalet, D. L., de Heuvel, E., Wallace, L., Bulloch, E., Turner, J., Wales, P. W., Nation, P., Wizzard, P. R., Hartmann, Bolette, Assad, M. & Holst, Jens Juul, 10 Jan 2014, In: Regulatory Peptides. 188, p. 70-80 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, , 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice
Sackmann-Sala, L., Berryman, D. E., Lubbers, E. R., Zhang, H., Vesel, C. B., Troike, K. M., Gosney, E. S., List, E. O. & Kopchick, J. J., 1 Jan 2014, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 69, 1, p. 34-43 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood Height and Body Mass Index Were Associated with Risk of Adult Thyroid Cancer in a Large Cohort Study
Kitahara, C. M., Gamborg, Michael Orland, Berrington de González, A., Sørensen, Thorkild I.A. & Baker, J. L., 1 Jan 2014, In: Cancer Research. 74, 1, p. 235-242 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
The ReproGen Consortium, T. R. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The ReproGen Consortium, T. R. C. & The GIANT Consortium, T. G. C., 1 Jan 2014, In: Human Molecular Genetics. 23, 16, p. 4452-4464 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting the intestinal L-cell for obesity and type 2 diabetes treatment
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes
Lepola, Mette Andersen, Sterner, M., Forsén, T., Käräjämäki, A., Rolandsson, O., Forsblom, C., Groop, P. H., Lahti, K., Nilsson, P. M., Groop, L. & Tuomi, T., 1 Jan 2014, In: Diabetologia. 57, 9, p. 1859-1868 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity
Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study
Hartvigsen, M. L., Gregersen, S., Lærke, H. N., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., Jan 2014, In: European Journal of Clinical Nutrition. 68, 1, p. 84-90 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance
Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of aspirin and statins on long-term survival in patients hospitalized with acute myocardial infarction complicated by heart failure: an analysis of 1706 patients
Lewinter, C., Bland, J. M., Crouch, S., Cleland, J. G. F., Doherty, P., LeWinter, M. M., Køber, Lars Valeur, Hall, A. S. & Gale, C. P., Jan 2014, In: European Journal of Heart Failure. 16, 1, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens
Svalgaard, J. D., Særmark, C., Dall, M., Buschard, K., Johansen, Jeanne Duus & Engkilde, K., Jan 2014, In: Immunologic Research. 58, 1, p. 40-50 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The authors reply
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
A 25-year-old woman with type 2 diabetes and liver disease
Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Prospective Study of Height and Body Mass Index in Childhood, Birth Weight, and Risk of Adult Glioma Over 40 Years of Follow-up
Kitahara, C. M., Gamborg, Michael Orland, Rajaraman, P., Sørensen, Thorkild I.A. & Baker, J. L., 2014, In: American Journal of Epidemiology. 180, 8, p. 821-829 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A combined analysis of 48 type 2 diabetes genetic risk variants shows no discriminative value to predict time to first prescription of a glucose lowering drug in Danish patients with screen detected type 2 diabetes.
Hornbak, M., Allin, K. H., Jensen, M. L., Lau, C. J., Witte, D. R., Jørgensen, M. E., Sandbæk, A., Lauritzen, T., Andersson, Åsa, Pedersen, Oluf Borbye & Hansen, Torben, 2014, In: PloS One. 9, 8, 10 p., e104837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, , 2014, In: Nature. 512, 7513, p. 190-193 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium
Su, Z., Labaj, P. P., Li, S., Thierry-Mieg, J., Thierry-Mieg, D., Shi, W., Wang, C., Schroth, G. P., Setterquist, R. A., Thompson, J. F., Jones, W. D., Xiao, W., Xu, W., Jensen, R. V., Kelly, R., Xu, J., Conesa, A., Furlanello, C., Gao, H., Hong, H. & 142 others, , 2014, In: Nature Biotechnology. 32, 9, p. 903-914 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-scale screen for coding variants predisposing to psoriasis
Tang, H., Jin, X., Li, Y., Jiang, H., Tang, X., Yang, X., Cheng, H., Qiu, Y., Chen, G., Mei, J., Zhou, F., Wu, R., Zuo, X., Zhang, Y., Zheng, X., Cai, Q., Yin, X., Quan, C., Shao, H., Cui, Y. & 47 others, , 2014, In: Nature Genetics. 46, 1, p. 45-+ 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity
Lantier, L., Fentz, J., Mounier, R., Leclerc, J., Treebak, Jonas Thue, Pehmøller, C. K., Sanz, N., Sakakibara, I., Saint-Amand, E., Rimbaud, S., Maire, P., Marette, A., Ventura-Clapier, R., Ferry, A., Wojtaszewski, Jørgen F P, Foretz, M. & Viollet, B., 2014, In: F A S E B Journal. 28, 7, p. 3211-3224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute and perinatal programming effects of a fat-rich diet on rat muscle mitochondrial function and hepatic lipid accumulation
Hellgren, L. I., Jensen, R. I., Waterstradt, M. S. G., Quistorff, B. & Lauritzen, Lotte, 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1170-1180 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute exercise and physiological insulin induce distinct phosphorylation signatures on TBC1D1 and TBC1D4 in human skeletal muscle
Treebak, Jonas Thue, Pehmøller, C., Kristensen, Jonas Møller, Kjøbsted, Rasmus, Birk, Jesper Bratz, Schjerling, Peter, Richter, Erik A., Goodyear, L. J. & Wojtaszewski, Jørgen F P, 2014, In: Journal of Physiology. 592, 2, p. 351-375 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acyl-CoA metabolism and partitioning
Grevengoed, Trisha Jean, Klett, E. L. & Coleman, R. A., 2014, In: Annual Review of Nutrition. 34, p. 1-30 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges
Kufareva, I., Katritch, V., Biggin, P., Kim, M., Park, K., Jung, S. W., Cho, A. E., Sands, Z. A., Ostopovici-Halip, L., Bologa, C. G., Norn, C., Brylinski, M., Skolnick, J., Keränen, H., Lenselink, B. E., Van Westen, G., Overington, J. P., De Teráán, H. G., Isberg, V., Fidom, K. M. & 96 others, , 2014, In: Structure. 22, 8, p. 1120-1139 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated catalog of reference genes in the human gut microbiome
Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, , 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins
Yuan, W., Xia, Y., Bell, C. G., Yet, I., Ferreira, T., Ward, K. J., Gao, F., Loomis, A. K., Hyde, C. L., Wu, H., Lu, H., Liu, Y., Small, K. S., Vinuela, A., Morris, A. P., Berdasco, M., Esteller, M., Brosnan, M. J., Deloukas, P., McCarthy, M. I. & 4 others, , 2014, In: Nature Communications. 5, 7 p., 5719.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist
Klementiev, B., Li, S., Korshunova, Irina, Dmytriyeva, O., Pankratova, Stanislava, Walmod, P. S., Kjær, L. K., Dahllöf, M. S., Lundh, M., Christensen, D. P., Mandrup-Poulsen, Thomas, Bock, E. & Berezin, V., 2014, In: Journal of Neuroinflammation. 11, 1, p. 27Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between Mediterranean and Nordic diet scores and changes in weight and waist circumference: influence of FTO and TCF7L2 loci
Roswall, N., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Romaguera, D., Larsen, S. C., Østergaard, J. N., Halkjaer, J., Vimaleswaran, K. S., Wareham, N. J., Bendinelli, B., Palli, D., Boer, J. M. A., van der A, D. L., Boeing, H., Loos, R. J. F., Sørensen, Thorkild I.A. & Tjønneland, A., 2014, In: The American Journal of Clinical Nutrition. 100, 4, p. 1188-1197 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor rev-erbα
Jager, J., Timothy O'Brien, W., Manlove, J., Krizman, E. N., Fang, B., Gerhart-Hines, Zach, Robinson, M. B., Klein, P. S. & Lazar, M. A., 2014, In: Molecular Endocrinology. 28, 4, p. 490-498 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birth weight, childhood body mass index, and height in relation to mammographic density and breast cancer: a register-based cohort study
Andersen, Zorana Jovanovic, Baker, J. L., Bihrmann, K., Vejborg, I. M. M., Sørensen, Thorkild I.A. & Lynge, Elsebeth, 2014, In: Breast cancer research : BCR. 16, 1, p. 1-11 11 p., R4.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood pressure levels in male carriers of Arg82Cys in CD300LG
Støy, J., Grarup, N., Hørlyck, A., Ibsen, L., Rungby, J., Poulsen, P. L., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye, Møller, N. & Kampmann, U., 2014, In: PLOS ONE. 9, 10, 6 p., e109646.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body Characteristics, Dietary Protein and Body Weight Regulation: Reconciling Conflicting Results from Intervention and Observational Studies?
Ankarfeldt, Mikkel Zöllner, Ängquist, Lars, Stocks, T., Jakobsen, M. U., Overvad, K., Halkjær, J., Saris, W. H. M., Astrup, A. & Sørensen, Thorkild I.A., 2014, In: P L o S One. 9, 7, p. 1-8 8 p., e101134.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cause-Specific Mortality According to Urine Albumin Creatinine Ratio in the General Population
Skaaby, T., Husemoen, L. L. N., Ahluwalia, Tarun Veer Singh, Rossing, Peter, Jørgensen, T., Thuesen, B. H., Pisinger, C., Rasmussen, K. & Linneberg, Allan René, 2014, In: PLOS ONE. 9, 3, p. 1-10 10 p., e93212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index and the risk of prostate cancer in adult men
Aarestrup, J., Gamborg, Michael Orland, Cook, M. B., Sørensen, Thorkild I.A. & Baker, J. L., 2014, In: B J C. 111, p. 207-212 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating sCD36 is associated with unhealthy fat distribution and elevated circulating triglycerides in morbidly obese individuals
Knøsgaard, L., Thomsen, S. B., Støckel, M., drb459, drb459 & Handberg, A., 2014, In: Nutrition and Diabetes. 4, 6 p., e114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women
Mark, A. B., Poulsen, M. W., Andersen, S., Andersen, J. M., Bak, M. J., Ritz, C., Holst, Jens Juul, Nielsen, J., de Courten, B., Dragsted, Lars Ove & Bügel, Susanne Gjedsted, 2014, In: Diabetes Care. 37, 1, p. 88-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defects in TLR3 expression and RNase L activation lead to decreased MnSOD expression and insulin resistance in muscle cells of obese people
Fabre, O. M. J., Breuker, C., Amouzou, C., Salehzada, T., Kitzmann, M., Mercier, J. & Bisbal, C., 2014, In: Cell Death & Disease. 5, p. 1-11 11 p., e1136.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts
Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, B. L. & Sørensen, Thorkild I.A., 2014, In: Nutrition Journal. 13, p. 1-11 11 p., 43.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary intervention modulates the gut microbiota and improves insulin resistance - a randomized controlled trial in obese postmenopausal women
Brahe, L. K., Le Chatelier, E., Prifti, E., Kennedy, S., Blædel, T., Håkansson, J., Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. & Larsen, L. H., 2014, In: Obesity Reviews. 15, Suppl. 2, p. 41-42 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Direct ChIP-bisulfite sequencing reveals a role of H3K27me3 mediating aberrant hypermethylation of promoter CpG islands in cancer cells
Gao, F., Ji, G., Gao, Z., Han, X., Ye, M., Yuan, Z., Luo, H., Huang, X., Natarajan, K., Wang, J., Yang, H. & Zhang, X., 2014, In: Genomics. 103, 2-3, p. 204-210 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy
Befroy, D. E., Perry, R. J., Jain, N., Dufour, S., Cline, G. W., Trimmer, J. K., Brosnan, J., Rothman, D. L., Petersen, K. F. & Shulman, G. I., 2014, In: Nature Medicine. 20, 1, p. 98-102 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia
Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, , 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do rapid BMI growth in childhood and early-onset obesity offer cardiometabolic protection to obese adults in mid-life? Analysis of a longitudinal cohort study of Danish men
Howe, L. D., Zimmermann, E., Weiss, R. & Sørensen, Thorkild I.A., 2014, In: B M J Open. 4, 4, p. 1-10 10 p., e004827.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial
Larsen, J. R., Vedtofte, L., Holst, Jens Juul, Oturai, P., Kjær, Andreas, Corell, C. U., Vilsbøll, T. & Fink-Jensen, Anders, 2014, In: B M J Open. 4, 3, p. 1-9 9 p., e004227.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Du er ikke alene Om bakterier og bevidsthed: Om bevidsthed og bakterier
Bencard, Adam, 2014, Im-materialitet (bevidsthed). Kirkhoff Eriksen, B. (ed.). Sorø: Sorø Kunstmuseum, Vol. 3. p. 69-78 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass
Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Serup, A. K. L., Albers, P. H., Hansen, D. L., Worm, D., Naver, L., Kristiansen, V. B., Wojtaszewski, Jørgen F P, Kiens, Bente, Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2014, In: Diabetes. 63, 5, p. 1725-1737 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals
Poulsen, M. W., Bak, M. J., Andersen, J. M., Monošík, R., Giraudi-Futin, A. C., Holst, Jens Juul, Nielsen, J., Lauritzen, Lotte, Larsen, L. H., Bügel, Susanne Gjedsted & Dragsted, Lars Ove, 2014, In: European Journal of Nutrition. 53, 2, p. 661-672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of PYY3-36 and GLP-1 on energy intake, energy expenditure and appetite in overweight men
Schmidt, J. B., Gregersen, N. T., Pedersen, S. D., Arentoft, J. L., Ritz, C., Schwartz, Thue W., Holst, Jens Juul, Astrup, A. & Sjödin, Anders Mikael, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 11, p. E1248-E1256 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of body size and change in body size from infancy through childhood on body mass index in adulthood
Bjerregaard, L. G., Rasmussen, K. M., Michaelsen, Kim F., Skytthe, A., Mortensen, Erik Lykke, Baker, J. L. & Sørensen, Thorkild I.A., 2014, In: International Journal of Obesity. 38, 10, p. 1305-1311 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of hydrolysed casein, intact casein and intact whey protein on energy expenditure and appetite regulation: a randomised, controlled, cross-over study
Bendtsen, L. Q., Lorenzen, J. K., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael & Astrup, A., 2014, In: British Journal of Nutrition. 112, 8, p. 1412-1422 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model
Gao, R., Liu, Y., Gjesing, A. M. P., Hollensted, M., Wan, X., He, S., Pedersen, Oluf Borbye, Yi, X., Wang, J. & Hansen, Torben, 2014, In: B M C Genetics. 15, 9 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer
Christensen, L. L., Holm, A., Rantala, J., Kallioniemi, O., Rasmussen, M. H., Ostenfeld, M. S., Dagnaes-Hansen, F., Oster, B., Schepeler, T., Tobiasen, H., Thorsen, K., Sieber, O. M., Gibbs, P., Lamy, P., Hansen, T. F., Jakobsen, A., Riising, E. M., Helin, K., Lubinski, J., Hagemann-Madsen, R. & 3 others, , 2014, In: PLOS ONE. 9, 6, p. e96767Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle
Sjøberg, K. A., Holst, Jens Juul, Rattigan, S., Richter, Erik A. & Kiens, Bente, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 4, p. E355-E362 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes 2012;61:1090-1099
Biensø, R. S., Ringholm, S., Kiilerich, K., Aachmann-Andersen, N., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2014, In: Diabetes. 63, 9, 1 p., 3159.Research output: Contribution to journal › Comment/debate › Research
- Published
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study
Langenberg, C., Sharp, S. J., Franks, P. W., Scott, R. A., Deloukas, P., Forouhi, N. G., Froguel, P., Groop, L. C., Hansen, T., Palla, L., Pedersen, O., Schulze, M. B., Tormo, M-J., Wheeler, E., Agnoli, C., Arriola, L., Barricarte, A., Boeing, H., Clarke, G. M., Clavel-Chapelon, F. & 27 others, , 2014, In: P L o S Medicine (Print). 11, 5, 14 p., e1001647.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene-physical activity interactions and their impact on diabetes
Kilpeläinen, Tuomas O. & Franks, P. W., 2014, In: Medicine and Sport Science. 60, p. 94-103 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 treatment may improve intestinal adaptation during weaning
Thymann, Thomas, Le Huërou-Luron, I., Petersen, Y. M., Hedemann, M. S., Elinf, J., Jensen, B. B., Holst, Jens Juul, Hartmann, Bolette & Sangild, Per Torp, 2014, In: Journal of Animal Science. 92, 5, p. 2070-2079 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1: effect on pro-atrial natriuretic peptide in healthy males
Skov, J., Holst, Jens Juul, Gøtze, J. P., Frøkiær, J. & Christiansen, J. S., 2014, In: Endocrine Connections. 3, 1, p. 11-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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