- 2013
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Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates
Vegge, A., Thymann, Thomas, Lund, P., Stoll, B., Bering, S. B., Hartmann, Bolette, Jelsing, J., Qvist, N., Burrin, D. G., Jeppesen, Palle Bekker, Holst, Jens Juul & Sangild, Per Torp, 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, 4, p. G277-G285 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin
Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, Jens, 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects
Asmar, M., Simonsen, L., Arngrim, N., Holst, Jens Juul, Dela, Flemming & Bülow, J., 2013, In: International journal of obesity (2005). 38, 2, p. 259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Harnessing the beneficial properties of adipogenic microbes for improving human health
Dhurandhar, N. V., Geurts, L., Atkinson, R. L., Casteilla, L., Clement, K., Gerard, P., Vijay-Kumar, M., Nam, J. H., Nieuwdorp, M., Trovato, G., Sørensen, Thorkild I.A., Vidal-Puig, A. & Cani, P. D., 2013, In: Obesity Reviews. 14, 9, p. 721-735 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion
Jonsson, Anna Elisabet, Hornbak, M., Gjesing, A. P., Allin, K. H., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Pedersen, O. & Hansen, T., 2013, In: Diabetologia. 56, 1, Supplement, p. S154-S154Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia
Shi, Y., Wang, J., Li, J-D., Ren, H., Guan, W., He, M., Yan, W., Zhou, Y., Hu, Z., Zhang, J., Xiao, J., Su, Z., Dai, M., Wang, J., Jiang, H., Guo, J., Zhou, Y., Zhang, F., Li, N., Du, J. & 8 others, , 2013, In: P L o S One. 8, 12, 9 p., e81884.Research output: Contribution to journal › Journal article › Research › peer-review
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Impairments in site-specific AS160 phosphorylation and effects of exercise training
Consitt, L. A., Van Meter, J., Newton, C. A., Collier, D. N., Dar, M. S., Wojtaszewski, Jørgen F P, Treebak, Jonas Thue, Tanner, C. J. & Houmard, J. A., 2013, In: Diabetes. 62, 10, p. 3437-3447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice
Clemmensen, Christoffer, Smajilovic, S., Madsen, A. N., Klein, A. B., Holst, Birgitte & Bräuner, Hans, 2013, In: Journal of Endocrinology. 217, 2, p. 151-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of SNPs in nutrient-sensitive candidate genes and gene-diet interactions on blood lipids: the DiOGenes study
Brahe, L. K., Ängquist, Lars, Larsen, L. H., Vimaleswaran, K. S., Hager, J., Viguerie, N., Loos, Ruth, Handjieva-Darlenska, T., Jebb, S. A., Hlavaty, P., Larsen, T. M., Martinez, J. A., Papadaki, A., Pfeiffer, A. F. H., van Baak, M. A., Sørensen, Thorkild I.A., Holst, C., Langin, D., Astrup, A. & Saris, W. H. M., 2013, In: British Journal of Nutrition. 110, 5, p. 790-796 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin Resistance and Impaired Pancreatic β-Cell Function in Adult Offspring of Women With Diabetes in Pregnancy
Kelstrup, L., Damm, Peter, Mathiesen, Elisabeth, Hansen, Torben, Vaag, Allan, Pedersen, Oluf Borbye & Clausen, Tine Dalsgaard, 2013, In: The Journal of clinical endocrinology and metabolism. 98, 9, p. 3793-3801 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation
Gao, F., Xia, Y., Wang, J., Luo, H., Gao, Z., Han, X., Zhang, J., Huang, X., Yao, Y., Lu, H., Yi, N., Zhou, B., Lin, Z., Wen, B., Zhang, X., Yang, H. & Wang, J., 2013, In: Epigenetics. 8, 4, p. 421-430 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intraoperative vector flow imaging of the heart
Hansen, Kristoffer Lindskov, Moller-Sorensen, H., Pedersen, M. M., Kjærgaard, Jesper, Nilsson, J. C., Lund, Jens, Nielsen, Michael Bachmann & Jensen, J. A., 2013, 2013 IEEE International Ultrasonics Symposium, IUS 2013. p. 1745-1748 4 p. 6725113. (IEEE International Ultrasonics Symposium, IUS).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?
van Raalte, D. H., Kwa, K. A. A., van Genugten, R. E., Tushuizen, M. E., Holst, Jens Juul, Deacon, Carolyn F., Karemaker, J. M., Heine, R. J., Mari, A. & Diamant, M., 2013, In: Metabolism. 62, 4, p. 568-577 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Late gestation undernutrition can predispose for visceral adiposity by altering fat distribution patterns and increasing the preference for a high-fat diet in early postnatal life
Nielsen, M. O., Kongsted, A. H., Thygesen, M. P., Strathe, A. B., Caddy, S., Quistorff, B., Jørgensen, W., Christensen, V. G., Husted, S. V., Chwalibog, André, Sejrsen, K., Purup, S., Svalastoga, Eiliv Lars, McEvoy, Fintan & Johnsen, L., 2013, In: British Journal of Nutrition. 109, 11, p. 2098-2110 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term renal outcome in the Steno 2 study
Ollgaard, J., Persson, F., Rossing, P., Parving, H., Pedersen, Oluf Borbye & Gaede, P. H., 2013, In: Diabetologia. 56, p. S45-S46Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low birth weight, adult BMI and inflammation in middle age
Pedersen, J. L. M., Rod, Naja Hulvej, Avlund, K., Budtz-Joergensen, Esben, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & Lund, Rikke, 2013, In: Gerontologist. 53, suppl. 1, p. 380Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes
Mari, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2013, In: PLOS ONE. 8, 9, p. e73154Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metagenomic species profiling using universal phylogenetic marker genes
Sunagawa, S., Mende, D. R., Zeller, G., Izquierdo-Carrasco, F., Berger, S. A., Kultima, J. R., Coelho, L. P., Arumugam, M., Tap, J., Nielsen, H. B., Rasmussen, S., Brunak, S., Pedersen, O. B., Guarner, F., de Vos, W. M., Wang, J., Li, J., Doré, J., Ehrlich, S. D., Stamatakis, A. & 1 others, , 2013, In: Nature Methods. 10, 12, p. 1196-1199 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modifiable environmental influences on body mass index shared by young adult brothers
Rokholm, B., Silventoinen, K., Tynelius, P., Sørensen, Thorkild I.A. & Rasmussen, F., 2013, In: International journal of obesity (2005). 37, p. 211-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair
Vestentoft, P. S., Jelnes, P., Andersen, Jesper Bøje, Tran, T. A. T., Jørgensen, T., Rasmussen, M., Lange, Jette Bornholdt, Grøvdal, L. M., Jensen, C. H., Vogel, Lotte, Thorgeirsson, S. S. & Bisgaard, Hanne Cathrine, 2013, In: Fibrogenesis & Tissue Repair. 6, 1, 15 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism
Quadri, M., Fang, M., Picillo, M., Olgiati, S., Breedveld, G. J., Graafland, J., Wu, B., Xu, F., Erro, R., Amboni, M., Pappata, S., Quarantelli, M., Annesi, G., Quattrone, A., Chien, H. F., Barbosa, E. R., Oostra, B. A., Barone, P., Wang, J. & Bonifati, V., 2013, In: Human Mutation. 34, 9, p. 1208-1215 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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N-3 polyunsaturated fatty acids, body fat and inflammation
Lund, A. Q., Hasselbalch, A. L., Gamborg, M., Skogstrand, K., Hougaard, D. M., Heitmann, B. L., Kyvik, K. O., Sørensen, Thorkild I.A. & Jess, T., 2013, In: Obesity Facts. 6, 4, p. 369-379 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimäki, T., Kreiner-Møller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E., Pfab, T. & 31 others, , 2013, In: Nature Genetics. 45, 1, p. 76-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Onykomykose hos små børn er sjælden, og behandlingen er en dermatologisk specialopgave
Haugaard, L. K., Skov, Lone, Arendrup, M. C. & Saunte, Ditte Marie, 2013, In: Ugeskrift for Laeger. 175, 40, p. 2343-2344 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pre- and postnatal nutrition in sheep affects ß-cell secretion and hypothalamic control
Kongsted, A. H., Husted, S. V., Thygesen, M. P., Christensen, V. G., Blache, D., Tolver, Anders, Larsen, T., Quistorff, B. & Nielsen, M. O., 2013, In: Journal of Endocrinology. 219, p. 159-171 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids
Orešic, M., Hyötyläinen, T., Kotronen, A., Gopalacharyulu, P., Nygren, H., Arola, J., Castillo, S., Mattila, I., Hakkarainen, A., Borra, R. J. H., Honka, M-J., Verrijken, A., Francque, S., Iozzo, P., Leivonen, M., Jaser, N., Juuti, A., Sørensen, T. I. A., Nuutila, P., Van Gaal, L. & 1 others, , 2013, In: Diabetologia. 56, 10, p. 2266-2274 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal Exposures to Perfluorinated Chemicals and Anthropometry at 7 Years of Age
Andersen, C. S., Fei, C., Gamborg, M., Nohr, E. A., Sørensen, Thorkild I.A. & Olsen, J., 2013, In: American Journal of Epidemiology. 178, 6, p. 921-927 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to selective serotonin reuptake inhibitors and childhood overweight at 7 years of age
Grzeskowiak, L., Gilbert, A. L., Sørensen, Thorkild I.A., Olsen, J., Sørensen, H. T., Pedersen, L. H. & Morrison, J. L., 2013, In: Annals of Epidemiology. 23, 11, p. 681-687 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young
Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes
Murholm, M., Isidor, Marie Sophie, Basse, A. L., Winther, Sally, Sørensen, C., Skovgaard-Petersen, J., Nielsen, M. M., Hansen, A. S., Quistorff, B. & Hansen, Jacob B., 2013, In: B M C Cell Biology. 14, 41, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler
Perry, R. J., Kim, T., Zhang, X., Lee, H., Pesta, D., Popov, V. B., Zhang, D., Rahimi, Y., Jurczak, M. J., Cline, G. W., Spiegel, D. A. & Shulman, G. I., 2013, In: Cell Metabolism. 18, 5, p. 740-748Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Review of 'Medical Imaging and Philosophy: Challenges, Reflections, Actions. Edited by Heiner Fangerau, Rethy Chhem, Irmgard Müller and Shih-Chang Wang.'
Whiteley, Louise, 2013, In: Isis. 104, 4, p. 820-821 2 p.Research output: Contribution to journal › Literature review › Research
- Published
Review of Duncan Wilson, Tissue Culture in Science and Society: The Public Life of a Biological Technique in Twentieth Century Britain
Tybjerg, Karin & Bencard, Adam, 2013, In: Isis. 104, p. 187-188 2 p.Research output: Contribution to journal › Review › Research
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Richness of human gut microbiome correlates with metabolic markers
Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J-M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K. S., Grarup, N., Jørgensen, T., Brandslund, I., Nielsen, H. B., Juncker, A., dos Santos, M. B. Q., Levenez, F. & 62 others, , 2013, In: Nature. 500, 7464, p. 541-546 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type
Sode, B. F., Allin, K. H., Dahl, Morten, Gyntelberg, F. & Nordestgaard, Børge, 2013, In: C M A J. 185, 5, p. E229-E237Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOAPfuse: an algorithm for identifying fusion transcripts from paired-end RNA-Seq data
Jia, W., Qiu, K., He, M., Song, P., Zhou, Q., Zhou, F., Yu, Y., Zhu, D., Nickerson, M. L., Wan, S., Liao, X., Zhu, X., Peng, S., Li, Y., Wang, J. & Guo, G., 2013, In: Genome Biology (Online Edition). 14, 2, 15 p., R12.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOAPfusion: a robust and effective computational fusion discovery tool for RNA-seq reads
Wu, J., Zhang, W., Huang, S., He, Z., Cheng, Y., Wang, J., Lam, T., Peng, Z. & Yiu, S., 2013, In: Bioinformatics. 29, 23, p. 2971-2978 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Social sciences and humanities contribution to tackle the obesity epidemic: challenges & potentials in obesity research towards Horizon 2020: concluding report
Holm, Lotte, Sandøe, Peter, Nielsen, Morten Ebbe Juul, Sørensen, Thorkild I.A., Børker Nielsen, P., Meidahl Petersen, A. & Verdich, C., 2013, København: University of Copenhagen. 41 p.Research output: Book/Report › Report
- Published
Sorafenib inhibits epithelial-mesenchymal transition through an epigenetic-based mechanism in human lung epithelial cells
Zhang, J., Chen, Y., Ji, G., Fang, W., Gao, Z., Liu, Y., Wang, J., Ding, X. & Gao, F., 2013, In: P L o S One. 8, 5, 9 p., e64954.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surgically Induced Interpregnancy Weight Loss and Prevalence of Overweight and Obesity in Offspring
Willmer, M., Berglind, D., Sørensen, Thorkild I.A., Näslund, E., Tynelius, P. & Rasmussen, F., 2013, In: P L o S One. 8, 12, p. 1-7 7 p., e82247.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFAP2B -Dietary Protein and Glycemic Index Interactions and Weight Maintenance after Weight Loss in the DiOGenes Trial
Stocks, T., Ängquist, Lars, Hager, J., Charon, C., Holst, C., Martinez, J. A., Saris, W. H. M., Astrup, A., Sørensen, Thorkild I.A. & Larsen, L. H., 2013, In: Human Heredity. 75, 2-4, p. 213-219 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression
Bjerre, C. A., Jensen, L. V., Belling, K. C., Würtz, S. Ø., Yadav, R., Lademann, U. A., Rigina, O., Do, K. N., Ditzel, H. J., Lykkesfeldt, A. E., Wang, J., Nielsen, H. B., Brünner, N., Gupta, R., Rasmussen, A. S. & Stenvang, Jan, 2013, In: Tumor Biology. 34, 6, p. 3839-3851 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release
Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of Roux-en-Y gastric bypass surgery on energy expenditure and appetite: a randomized human study including “pair fed” control subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S., Nielsen, M. S., Nielsen, L. V., Holst, Jens Juul, Hansen, D. L., Dorm, D. W., Madsbad, Sten, Clausen, T. R. C., Ritz, C., Astrup, A. & Sjödin, Anders Mikael, 2013, In: Obesity Facts. 6, suppl. 1, p. 28 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial
Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of long-term taurine supplementation and fructose feeding on glucose and lipid homeostasis in Wistar rats
Larsen, L. H., Orstrup, L. K. H., Hansen, S. H., Grunnet, N., Quistorff, B. & Mortensen, Ole Hartvig, 2013, In: Advances in Experimental Medicine and Biology. 776, p. 39-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transient activation of mTOR following forced treadmill exercise in rats
Elfving, B., Christensen, T., Ratner, C., Wienecke, Jacob & Klein, A. B., 2013, In: Synapse. 67, 9, p. 620-625 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatments for Neurodevelopmental Disorders: Evidence, Advocacy, and the Internet
Di Pietro, N. C., Whiteley, Louise, Mizgalewicz, A. & Illes, J., 2013, In: Journal of Autism and Developmental Disorders. 43, 1, p. 122-133 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trends in prevalence of overweight and obesity in danish infants, children and adolescents--are we still on a plateau?
Morgen, C. S., Rokholm, B., Sjöberg Brixval, C., Schou Andersen, C., Geisler Andersen, L., Rasmussen, M., Nybo Andersen, Anne-Marie, Due, P. & Sørensen, Thorkild I.A., 2013, In: P L o S One. 8, 7, p. e69860Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two Weeks of Metformin Treatment Induces AMPK Dependent Enhancement of Insulin Stimulated Glucose Transport in Mouse Skeletal Muscle
Kristensen, Jonas Møller, Treebak, Jonas Thue, Goodyear, L. J. & Wojtaszewski, Jørgen F P, 2013, In: Diabetes. 62, Suppl. 1, p. A462 1 p., 1780-P.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Utilizing social media to study information-seeking and ethical issues in gene therapy
Robillard, J. M., Whiteley, Louise, Johnson, T. W., Lim, J., Wasserman, W. W. & Illes, J., 2013, In: Journal of Medical Internet Research. 15, 3, p. e44Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1
Cao, Y., Gao, Z., Li, L., Jiang, X., Shan, A., Cai, J., Peng, Y., Li, Y., Jiang, X., Huang, X., Wang, J., Wei, Q., Qin, G., Zhao, J., Jin, X., Liu, L., Li, Y., Wang, W., Wang, J. & Ning, G., 2013, In: Nature Communications. 4, 6 p., 2810.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression
Tammiste, A., Jiang, T., Fischer, K., Mägi, R., Krjutskov, K., Pettai, K., Esko, T., Li, Y., Tansey, K. E., Carroll, L. S., Uher, R., McGuffin, P., Vosa, U., Tsernikova, N., Saria, A., Ng, P. C., Eller, T., Vasar, V., Nutt, D. J., Maron, E. & 2 others, , 2013, In: Journal of Psychopharmacology. 27, 10, p. 915-920 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
Guo, G., Sun, X., Chen, C., Wu, S., Huang, P., Li, Z., Dean, M., Huang, Y., Jia, W., Zhou, Q., Tang, A., Yang, Z., Li, X., Song, P., Zhao, X., Ye, R., Zhang, S., Lin, Z., Qi, M., Wan, S. & 36 others, , 2013, In: Nature Genetics. 45, 12, p. 1459-1463 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Whole-genome sequences of DA and F344 rats with different susceptibilities to arthritis, autoimmunity, inflammation and cancer
Guo, X., Brenner, M., Zhang, X., Laragione, T., Tai, S., Li, Y., Bu, J., Yin, Y., Shah, A. A., Kwan, K., Li, Y., Wang, J. & Gulko, P. S., 2013, In: Genetics. 194, 4, p. 1017-1028 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
Kan, Z., Zheng, H., Liu, X., Li, S., Barber, T. D., Gong, Z., Gao, H., Hao, K., Willard, M. D., Xu, J., Hauptschein, R., Rejto, P. A., Fernandez, J., Wang, G., Zhang, Q., Wang, B., Chen, R., Wang, J., Lee, N. P., Zhou, W. & 30 others, , 2013, In: Genome Research. 23, p. 1422-1433 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome sequencing reveals untapped genetic potential in Africa's indigenous cereal crop sorghum
Mace, E. S., Tai, S., Gilding, E. K., Li, Y., Prentis, P. J., Bian, L., Campbell, B. C., Hu, W., Innes, D. J., Han, X., Cruickshank, A., Dai, C., Frere, C., Zhang, H., Hunt, C. H., Wang, X., Shatte, T., Wang, M., Su, Z., Li, J. & 4 others, , 2013, In: Nature Communications. 4, 9 p., 2320.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation
Valentin-Hansen, L., Holst, Birgitte, Frimurer, Thomas Michael, Schwartz, Thue W. & Hansen, L. V., 21 Dec 2012, In: Journal of Biological Chemistry. 287, 52, p. 43516-43526 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance
Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., Emanuelli, Brice, Smyth, G., Cinti, S., Newgard, C. B., Gibson, B. W., Larsson, N. & Kahn, C. R., 5 Dec 2012, In: Cell Metabolism. 16, 6, p. 765-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adult glucose metabolism in extremely birthweight-discordant monozygotic twins
Frost, M., Petersen, I., Brixen, K., Beck-Nielsen, H., Holst, Jens Juul, Christiansen, L., Højlund, K. & Christensen, K., Dec 2012, In: Diabetologia. 55, 12, p. 3204-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets
van der Meer, Y., Gerrits, W. J. J., van den Bosch, M., Holst, Jens Juul, Moreto, M., Buurman, W. A., Kulik, W. & van Kempen, T. A. T. G., Dec 2012, In: Journal of Animal Science. 90 Suppl 4, p. 302-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissecting signaling and functions of adhesion G protein-coupled receptors
Araç, D., Aust, G., Calebiro, D., Engel, F. B., Formstone, C., Goffinet, A., Hamann, J., Kittel, R. J., Liebscher, I., Lin, H-H., Monk, K. R., Petrenko, A., Piao, X., Prömel, S., Schiöth, H. B., Schwartz, T. W., Stacey, M., Ushkaryov, Y. A., Wobus, M., Wolfrum, U. & 2 others, , Dec 2012, In: Annals of the New York Academy of Sciences. 1276, p. 1-25 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a common variant of the PCSK2 gene on reduced insulin secretion
Jonsson, Anna Elisabet, Isomaa, B., Tuomi, T., Eriksson, J. G., Groop, L. & Lyssenko, V., Dec 2012, In: Diabetologia. 55, 12, p. 3245-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity
Solomon, T. P. J., Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul & Pedersen, Bente Klarlund, Dec 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4682-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia
Gejl, M., Egefjord, L., Lerche, S., Vang, K., Bibby, B. M., Holst, Jens Juul, Mengel, A., Møller, N., Rungby, J., Brock, B. & Gjedde, Albert, Dec 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 12, p. 2146-2152 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves
Taylor-Edwards, C. C., Burrin, D. G., Kristensen, N. B., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., Dec 2012, In: Animal. 6, 12, p. 1985-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)
Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice
Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase
Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zeqiraj, E., Turk, B. E. & Sakamoto, Kei, 1 Nov 2012, In: Cellular Signalling. 24, 11, p. 2085-2094 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. A. & Heise, T., Nov 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)
Benned-Jensen, T., Norn, C., Laurent, S., Madsen, C. M., Larsen, H. M., Arfelt, K. N., Wolf, R. M., Frimurer, Thomas Michael, Sailer, A. W. & Rosenkilde, Mette, 12 Oct 2012, In: The Journal of Biological Chemistry. 287, 42, p. 35470-83 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells
Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery
Bryant, E. J., King, N. A., Falkén, Y., Hellström, P. M., Holst, Jens Juul, Blundell, J. E. & Näslund, E., 12 Oct 2012, In: Surgery for Obesity and Related Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of an Osteopontin gene promoter polymorphism with susceptibility to diabetic nephropathy in Asian Indians
Cheema, B. S., Iyengar, S., Ahluwalia, Tarun Veer Singh, Kohli, H. S., Sharma, R., Shah, V. N., Bhansali, A., Sakhuja, V. & Khullar, M., 9 Oct 2012, In: Clinica chimica acta; international journal of clinical chemistry. 413, 19-20, p. 1600-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational design of conformationally constrained cyclopentapeptide antagonists for C-x-C chemokine receptor 4 (CXCR4)
Mungalpara, J., Thiele, S., Eriksen, Ø., Eksteen, J., Rosenkilde, Mette & Våbenø, J., 9 Oct 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10287-10291 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection
Ekholm, E., Shaat, N. & Holst, Jens Juul, Oct 2012, In: Acta Diabetologica. 49, 5, p. 349-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol
Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
miRSeqNovel: an R based workflow for analyzing miRNA sequencing data
Qian, K., Auvinen, E., Greco, D. & Auvinen, P., Oct 2012, In: Molecular and Cellular Probes. 26, 5, p. 208-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors
Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses
Procaccini, C., De Rosa, V., Galgani, M., Carbone, F., Cassano, S., Greco, D., Qian, K., Auvinen, P., Calì, G., Stallone, G., Formisano, L., La Cava, A. & Matarese, G., 15 Sep 2012, In: Journal of Immunology. 189, 6, p. 2941-53 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor
Hansen, L. V., Groenen, M., Nygaard, R., Frimurer, Thomas Michael, Holliday, N. D. & Schwartz, Thue W., 14 Sep 2012, In: Journal of Biological Chemistry. 287, 38, p. 31973-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor
Els, S., Schild, E., Petersen, P. S., Kilian, T., Mokrosinski, J., Frimurer, Thomas Michael, Chollet, C., Schwartz, Thue W., Holst, Birgitte & Beck-Sickinger, A. G., 13 Sep 2012, In: Journal of Medicinal Chemistry. 55, 17, p. 7437-49 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A metabolic prosurvival role for PML in breast cancer
Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure
Brinkman, A. S., Murali, S. G., Hitt, S., Solverson, P. M., Holst, Jens Juul & Ney, D. M., 1 Sep 2012, In: A J P: Gastrointestinal and Liver Physiology (Online). 303, 5, p. G610-22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs
Stoll, B., Puiman, P. J., Cui, L., Chang, X., Benight, N. M., Bauchart-Thevret, C., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 538-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model
Barnes, J. L., Hartmann, Bolette, Holst, Jens Juul & Tappenden, K. A., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 524-37 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, D. G. R. A. M. (. C., Sep 2012, In: Nature Genetics. 44, 9, p. 991-1005 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Morris, A. P., Voight, B. F., Teslovich, T. M., Ferreira, T., Segrè, A. V., Steinthorsdottir, V., Strawbridge, R. J., Khan, A. H., Grallert, H., Mahajan, A., Prokopenko, I., Kang, H. M., Dina, C., Esko, T., Fraser, R. M., Kanoni, S., Kumar, A., Lagou, V., Langenberg, C., Luan, J. & 31 others, , Sep 2012, In: Nature Genetics. 44, 9, p. 981-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop
Mokrosinski, J., Frimurer, Thomas Michael, Sivertsen, B., Schwartz, Thue W. & Holst, Birgitte, Sep 2012, In: Journal of Biological Chemistry. 287, p. 33488-33502 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation
Fabre, O. M. J., Salehzada, T., Lambert, K., Boo Seok, Y., Zhou, A., Mercier, J. & Bisbal, C., Sep 2012, In: Cell Death and Differentiation. 19, 9, p. 1470-81 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women
Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Råd. Sundhedsstyrelsen svigter overvægtige
Astrup, A., Bitz, C. & Sørensen, Thorkild I.A., 27 Aug 2012, In: Politiken. p. 8 1 p.Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication
- Published
Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside
Midtkandal, R. R., Redpath, P., Trammell, Sam, MacDonald, S. J. F., Brenner, C. & Migaud, M. E., 15 Aug 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 16, p. 5204-5207 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism
Szekeres, F., Chadt, A., Tom, R. Z., Deshmukh, Atul Shahaji, Chibalin, A. V., Björnholm, M., Al-Hasani, H. & Zierath, Juleen R, 15 Aug 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 4, p. E524-33Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of intravenous infusions of PYY3-36 and GLP-1, as monoinfusion and in combination, on ad libitum energy intake in healthy obese subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Schwartz, Thue W., Astrup, A. & Sjödin, Anders Mikael, 10 Aug 2012, In: Regulatory Peptides. 177, Supplement, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes
Muscelli, E., Casolaro, A., Gastaldelli, A., Mari, A., Seghieri, G., Astiarraga, B., Chen, Y., Alba, M., Holst, Jens Juul & Ferrannini, E., Aug 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2818-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
Taneera, J., Lang, S., Sharma, A., Fadista, J., Zhou, Y., Ahlqvist, E., Jonsson, A. E., Lyssenko, V., Vikman, P., Hansson, O., Parikh, H., Korsgren, O., Soni, A., Krus, U., Zhang, E., Jing, X-J., Esguerra, J. L. S., Wollheim, C. B., Salehi, A., Rosengren, A. & 2 others, , 3 Jul 2012, In: Cell Metabolism. 16, 1, p. 122-34 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study
Lepola, Mette Andersen, Lundgren, V., Isomaa, B., Groop, L. & Tuomi, T., 1 Jul 2012, In: European Journal of Endocrinology. 167, 1, p. 27-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
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