Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2011
  2. Published

    Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach

    Thiele, S., Steen, A., Jensen, P. C., Mokrosinski, J., Frimurer, Thomas Michael & Rosenkilde, Mette, 2011, In: Journal of Biological Chemistry. 286, 43, p. 37543-54 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    An Aboriginal Australian genome reveals separate human dispersals into Asia

    Rasmussen, M., Guo, X., Wang, Y., Lohmueller, K. E., Rasmussen, S., Albrechtsen, A., Skotte, L., Lindgreen, S., Metspalu, M., Jombart, T., Kivisild, T., Zhai, W., Eriksson, A., Manica, A., Orlando, L., De La Vega, F. M., Tridico, S., Metspalu, E., Nielsen, K., Avila Arcos, M. D. C. & 38 others, Moreno Mayar, J. Víctor, Muller, C., Dortch, J., Gilbert, M Thomas P, Lund, O., Wesolowska, A., Karmin, M., Weinert, L. A., Wang, B., Li, J., Tai, S., Xiao, F., Hanihara, T., van Driem, G., Jha, A. R., Ricaut, F., de Knijff, P., Migliano, A. B., Gallego Romero, I., Kristiansen, Karsten, Lambert, D. M., Brunak, Søren, Forster, P., Brinkmann, B., Nehlich, O., Bunce, M., Richards, M., Gupta, R., Bustamante, C. D., Krogh, Anders, Foley, R. A., Lahr, M. M., Balloux, F., Sicheritz-Pontén, T., Villems, R., Nielsen, Rasmus, Wang, J. & Willerslev, Eske, 2011, In: Science. 334, 6052, p. 94-98 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression

    Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Association between CST3 rs2424577 polymorphism and corpulence related phenotypes during lifetime in populations of European ancestry

    Hooton, H., Dubern, B., Henegar, C., Paternoster, L., Nohr, E. A., Alili, R., Rousseau, F., Pelloux, V., Galan, P., Hercberg, S., Arner, P., Sørensen, Thorkild I.A. & Clément, K., 2011, In: Obesity Facts. 4, 2, p. 131-44 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Associations between APOE variants and metabolic traits and the impact of psychological stress

    Kring, S. I. I., Barefoot, J., Brummett, B. H., Boyle, S. H., Siegler, I. C., Toubro, S., Hansen, T., Astrup, A., Pedersen, Oluf Borbye, Williams, R. B. & Sørensen, Thorkild I.A., 2011, In: PLoS ONE. 6, 1, 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Back to basics

    Söderqvist, Thomas & Arnold, Ken, 2011, In: Museums Journal. 111, 2, p. 22-27 6 p.

    Research output: Contribution to journal › Journal article › Commissioned

  8. Published

    Balance og stofskifte: To forestillinger om kroppen i medicinens historie

    Bencard, Adam, 2011

    Research output: Non-textual form › 2D/3D (psysical products) › Communication

  9. Published

    C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells

    Galuska, D., Pirkmajer, S., Barrès, Romain, Ekberg, K., Wahren, J. & Chibalin, A. V., 2011, In: P L o S One. 6, 12, p. e28294

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    C-reactive protein and cancer

    Allin, K. H., 2011, Faculty of Health Sciences, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis

  11. Published

    C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients

    Zimmermann, E., Anty, R., Tordjman, J., Verrijken, A., Gual, P., Tran, A., Iannelli, A., Gugenheim, J., Bedossa, P., Francque, S., Le Marchand-Brustel, Y., Clement, K., Van Gaal, L., Sørensen, Thorkild I.A. & Jess, T., 2011, In: Journal of Hepatology. 55, 3, p. 660-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides

    Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Changes in waist circumference and the incidence of acute myocardial infarction in middle-aged men and women

    Berentzen, T. L., Jakobsen, M. U., Stegger, J. G., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 10, p. e26849

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Changes in waist circumference and the incidence of diabetes in middle-aged men and women

    Berentzen, T. L., Jakobsen, M. U., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 8, p. e23104

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Chronic AICAR treatment, but not voluntary exercise training, increases nicotinamide phosphoribosyl transferase (Nampt) protein expression in an AMPK-dependent manner in mouse quadriceps muscle

    Brandauer, J. & Treebak, Jonas Thue, 2011, In: FASEB Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Chronic sympathetic activation promotes downregulation of ß-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

    Soltysinska, E., Thiele, S., Osadchiy, O. & Olesen, Søren-Peter, 2011, In: Pflügers Archiv - European Journal of Physiology. 462, 4, p. 529-43 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Comparison of the relative contributions of intra-abdominal and liver fat to components of the metabolic syndrome

    Kotronen, A., Yki-Järvinen, H., Sevastianova, K., Bergholm, R., Hakkarainen, A., Pietiläinen, K. H., Juurinen, L., Lundbom, N. & Sørensen, Thorkild I.A., 2011, In: Obesity. 19, 1, p. 23-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study

    Brock Jacobsen, I., Vind, B. F., Korsholm, L., Flyvbjerg, A., Frystyk, J., Holst, Jens Juul, Beck-Nielsen, H. & Henriksen, J. E., 2011, In: Acta Physiologica (Print). 202, 3, p. 337-347 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Delayed ß-cell response and glucose intolerance in young women with Turner syndrome

    Hjerrild, B. E., Holst, Jens Juul, Juhl, C., Christiansen, J. S., Schmitz, O. & Gravholt, C. H., 2011, In: B M C Endocrine Disorders. 11, p. 11-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism

    Macotela, Y., Emanuelli, Brice, Bång, A. M., Espinoza, D. O., Boucher, J., Beebe, K., Gall, W. & Kahn, C. R., 2011, In: PLOS ONE. 6, 6, p. e21187

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs

    Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  22. Published

    Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes

    Torekov, Signe Sørensen, Kipnes, M. S., Harley, R. E., Holst, Jens Juul & Ehlers, M. R., 2011, In: Diabetes, Obesity and Metabolism. 13, 7, p. 639-43 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Education modifies genetic and environmental influences on BMI

    Johnson, W., Kyvik, K. O., Skytthe, A., Deary, I. J. & Sørensen, Thorkild I.A., 2011, In: P L o S One. 6, 1, p. e16290

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes

    Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In: Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Estimation of allele frequency and association mapping using next-generation sequencing data

    Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, Niels, Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction

    Lønborg, Jacob Thomsen, Vejlstrup, N., Kelbæk, H., Bøtker, H. E., Kim, W. Y., Mathiasen, A. B., Jørgensen, E., Helqvist, S., Saunamäki, K., Clemmensen, P., Holmvang, Lene, Thuesen, L., Krusell, L. R., Jensen, J. S., Køber, Lars Valeur, Treiman, M., Holst, Jens Juul & Engstrøm, Thomas, 2011, In: European Heart Journal. 33, 12, p. 1491-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Fatty acid composition in organs.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contribution › Research

  29. Published

    Fatty acid composition in red blood cells.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contribution › Research

  30. Published

    Fatty acid composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contribution › Research

  31. Published

    GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes

    Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Gastric bypass and duodenal and gastric feeding: a comment to Hansen et al

    Jorgensen, N. B., Dirksen, C., Holst, Jens Juul & Madsbad, Sten, 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 5, p. G938-G9389 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Gastric emptying of orally administered glucose solutions and incretin hormone responses are unaffected by laparoscopic adjustable gastric banding

    Usinger, Lotte, Hansen, K. B., Kristiansen, V. B., Larsen, S., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Obesity Surgery. 21, 5, p. 625-32 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Genetic and environmental influences on oxidative damage assessed in elderly Danish twins

    Broedbaek, K., Ribel-Madsen, R., Henriksen, T., Weimann, A., Petersen, M., Andersen, Jon Thor Trærup, Afzal, Shoaib, Hjelvang, B., Roberts, L. J., Vaag, Allan, Poulsen, P. & Poulsen, Henrik Enghusen, 2011, In: Free Radical Biology & Medicine. 50, 11, p. 1488-91 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change--the DiOGenes study

    Du, H., Ängquist, Lars, Vimaleswaran, K. S., Hansen, R. D., van der, D. L., Holst, C., Tjønneland, A., Overvad, K., Jakobsen, M. U., Boeing, H., Meidtner, K., Palli, D., Masala, G., Bouatia-Naji, N., Saris, W. H. M., Feskens, E. J. M., Wareham, N. J., Sørensen, Thorkild I.A. & Loos, R. J. F., 2011, In: P L o S One. 6, 2, p. e17436

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index

    Freathy, R. M., Kazeem, G. R., Morris, R. W., Johnson, P. C. D., Paternoster, L., Ebrahim, S., Hattersley, A. T., Hill, A., Hingorani, A. D., Holst, C., Jefferis, B. J., Kring, S. I. I., Mooser, V., Padmanabhan, S., Preisig, M., Ring, S. M., Sattar, N., Upton, M. N., Vollenweider, P., Waeber, G. & 8 others, Sørensen, Thorkild I.A., Frayling, T. M., Watt, G., Lawlor, D. A., Whincup, P. H., Tozzi, F., Davey Smith, G. & Munafò, M., 2011, In: International Journal of Epidemiology. 40, 6, p. 1617-28 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes

    Ketterer, C., Müssig, K., Heni, M., Dudziak, K., Randrianarisoa, E., Wagner, R., Machicao, F., Stefan, N., Holst, Jens Juul, Fritsche, A., Häring, H. & Staiger, H., 2011, In: Metabolism. 60, 9, p. 1325-1333 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques

    Yan, G., Zhang, G., Fang, X., Zhang, Y., Li, C., Ling, F., Cooper, D. N., Li, Q., Li, Y., van Gool, A. J., Du, H., Chen, J., Chen, R., Zhang, P., Huang, Z., Thompson, J. R., Meng, Y., Bai, Y., Wang, J., Zhuo, M. & 26 others, Wang, T., Huang, Y., Wei, L., Li, J., Wang, Z., Hu, H., Yang, P., Le, L., Stenson, P. D., Li, B., Liu, X., Ball, E. V., An, N., Huang, Q., Zhang, Y., Fan, W., Zhang, X., Li, Y., Wang, W., Katze, M. G., Su, B., Nielsen, Rasmus, Yang, H., Wang, J., Wang, X. & Wang, J., 2011, In: Nature Biotechnology. 29, 11, p. 1019-1023 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  39. Published

    Genome sequencing reveals insights into physiology and longevity of the naked mole rat

    Kim, E. B., Fang, X., Fushan, A. A., Huang, Z., Lobanov, A. V., Han, L., Marino, S. M., Sun, X., Turanov, A. A., Yang, P., Yim, S. H., Zhao, X., Kasaikina, M. V., Stoletzki, N., Peng, C., Polak, P., Xiong, Z., Kiezun, A., Zhu, Y., Chen, Y. & 16 others, Kryukov, G. V., Zhang, Q., Peshkin, L., Yang, L., Bronson, R. T., Buffenstein, R., Wang, B., Han, C., Li, Q., Chen, L., Zhao, W., Sunyaev, S. R., Park, T. J., KU, thw266, Wang, J. & Gladyshev, V. N., 2011, In: Nature Photographer. 479, 7372, p. 223-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Genome wide association study identifies KCNMA1 contributing to human obesity

    Jiao, H., Arner, P., Hoffstedt, J., Brodin, D., Dubern, B., Czernichow, S., van't Hooft, F., Axelsson, T., Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A., Hebebrand, J., Kere, J., Dahlman-Wright, K., Hamsten, A., Clement, K. & Dahlman, I., 2011, In: B M C Medical Genomics. 4, p. 51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Genome-wide population-based association study of extremely overweight young adults--the GOYA study

    Paternoster, L., Evans, D. M., Nohr, E. A., Holst, C., Gaborieau, V., Brennan, P., Gjesing, A. P., Grarup, N., Witte, D. R., Jørgensen, T., Linneberg, A. R., Lauritzen, T., Sandbaek, A., Hansen, T., Pedersen, O. B., Elliott, K. S., Kemp, J. P., St Pourcain, B., McMahon, G., Zelenika, D. & 5 others, Hager, J., Lathrop, M., Timpson, N. J., Smith, G. D. & Sørensen, Thorkild I.A., 2011, In: P L o S One. 6, 9, e24303.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Glucagon like-peptide 1 receptor and the liver

    Pedersen, Jens & Holst, Jens Juul, 2011, In: Liver international : official journal of the International Association for the Study of the Liver. 31, 9, p. 1243-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Glucagon-like peptide 2 (Glp-2) stimulates intestinal function during weaning

    Thymann, Thomas, Huërou-Luron, I. L., Petersen, Y. M., Hedemann, M. S., Elnif, J., Jensen, B. B., Hartmann, Bolette, Holst, Jens Juul & Sangild, Per Torp, 2011, 44th annual meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, 2011: programme and abstract booklet. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), p. 202 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

  44. Published

    Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves

    Taylor-Edwards, C. C., Burrin, D. G., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., 2011, In: Journal of Dairy Science. 94, 2, p. 888-898 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B

    Hribal, M. L., Presta, I., Procopio, T., Marini, M. A., Stancáková, A., Kuusisto, J., Andreozzi, F., Hammarstedt, A., Jansson, P., Grarup, Niels, Hansen, Torben, Walker, M., Stefan, N., Fritsche, A., Häring, H. U., Pedersen, Oluf Borbye, Smith, U., Laakso, M., Sesti, G. & EUGENE2 Consortium, E. C., 2011, In: Diabetologia. 54, 4, p. 795-802 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans

    Christensen, M., Vedtofte, L., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    High brain Lactate: High brain lactate is not caused by a shift in the lactate dehydrogenase A/B ratio.

    Quistorff, B. & Grunnet, N., 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 7, p. E21 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

    Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, GIANT Consortium, G. C., 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Human papillomavirus 16 E5 modulates the expression of host microRNAs

    Greco, D., Kivi, N., Qian, K., Leivonen, S., Auvinen, P. & Auvinen, E., 2011, In: PloS one. 6, 7, p. e21646

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Impaired regulation of the incretin effect in patients with type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, drb459, drb459, Holst, Jens Juul & Vilsbøll, Tina, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes

    Engelen, L., Lund, S. S., Ferreira, I., Tarnow, L., Parving, H., Gram, J., Winther, Kaj, Pedersen, Oluf Borbye, Teerlink, T., Barto, R., Stehouwer, C. D. A., Vaag, Allan & Schalkwijk, C. G., 2011, In: European Journal of Endocrinology. 164, 3, p. 371-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects

    Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 447-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion

    Lou, P., Gustavsson, N., Wang, Y., Radda, G. K. & Han, W., 2011, In: PloS one. 6, 10, p. e26671

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial

    Raben, Anne, Møller, B. K., Flint, A., Vasilaris, T. H., Møller, A. C., Holst, Jens Juul & Astrup, A., 2011, In: Food & Nutrition Research. 55, 5961, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Increasing genetic variance of body mass index during the Swedish obesity epidemic

    Rokholm, B., Silventoinen, K., Tynelius, P., Gamborg, M., Sørensen, Thorkild I.A. & Rasmussen, F., 2011, In: P L o S One. 6, 11, p. e27135

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index

    Zimmermann, E., Skogstrand, K., Hougaard, D. M., Astrup, A., Hansen, T., Pedersen, O., Sørensen, Thorkild I.A. & Jess, T., 2011, In: P L o S One. 6, 1, p. e15958 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes

    Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Inkretiner

    Vilsbøll, Tina & Holst, Jens Juul, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2 ed. København: Munksgaard , p. 67-74 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  59. Published

    Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile

    Amlacher, S., Sarges, P., Flemming, D., van Noort, V., Kunze, R., Devos, D. P., Arumugam, Mani, Bork, P. & Hurt, E., 2011, In: Cell. 146, 2, p. 277-89 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Intake of total, animal and plant protein and subsequent changes in weight or waist circumference in European men and women: the Diogenes project

    Halkjær, J., Olsen, A., Overvad, K., Jakobsen, M. U., Boeing, H., Buijsse, B., Palli, D., Tognon, G., Du, H., van der, D. L., Forouhi, N. G., Wareham, N. J., Feskens, E. J. M., Sørensen, Thorkild I.A. & Tjønneland, A., 2011, In: International Journal of Obesity. 35, 8, p. 1104-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation

    Fredheim, S., Svensson, Jannet, Pørksen, S., Hansen, L., Hansen, Torben, Pedersen, Oluf Borbye, Mortensen, H. B., Barbetti, F. & Nielsen, L. B., 2011, In: Case Reports in Genetics. 2011, p. 258978

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion

    Witte, A., Grybäck, P., Jacobsson, H., Näslund, E., Hellström, P. M., Holst, Jens Juul, Hilsted, Linda & Schmidt, P. T., 2011, In: Scandinavian Journal of Gastroenterology. Supplement. 46, 4, p. 428-35 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Is socioeconomic status of the rearing environment causally related to obesity in the offspring?

    Fontaine, K. R., Robertson, H. T., Holst, C., Desmond, R., Stunkard, A. J., Sørensen, Thorkild I.A. & Allison, D. B., 2011, In: P L o S One. 6, 11, p. e27692

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    LIF is a contraction-induced myokine stimulating human myocyte proliferation

    Broholm, C., Laye, M. J., Brandt, C., Vadalasetty, R., Pilegaard, Henriette, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2011, In: Journal of Applied Physiology. 111, 1, p. 251-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Lifelong doubling of mortality in men entering adult life as obese

    Zimmermann, E., Holst, C. & Sørensen, Thorkild I.A., 2011, In: International Journal of Obesity. 35, 9, p. 1193-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials

    Buse, J. B., Garber, A., Rosenstock, J., Schmidt, W. E., Brett, J. H., Videbæk, N., Holst, Jens Juul & Nauck, M., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 6, p. 1695-702 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Lixisenatide for type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Macronutrient composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contribution › Research

  69. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test

    Møller, J. B., Jusko, W. J., Gao, W., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Overgaard, R. V., Madsen, H. & Ingwersen, S. H., 2011, In: Journal of Pharmacokinetics and Pharmacodynamics. 38, 6, p. 713-25 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Medical instruments in museums: Immediate impressions and historical meanings

    Söderqvist, Thomas & Arnold, Ken, 2011, In: Isis. 102, 4, p. 718-729 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications

    Yilmaz, P., Kottmann, R., Field, D., Knight, R., Cole, J. R., Amaral-Zettler, L., Gilbert, J. A., Karsch-Mizrachi, I., Johnston, A., Cochrane, G., Vaughan, R., Hunter, C., Park, J., Morrison, N., Rocca-Serra, P., Sterk, P., Arumugam, M., Bailey, M., Baumgartner, L., Birren, B. W. & 78 others, Blaser, M. J., Bonazzi, V., Booth, T., Bork, P., Bushman, F. D., Buttigieg, P. L., Chain, P. S. G., Charlson, E., Costello, E. K., Huot-Creasy, H., Dawyndt, P., DeSantis, T., Fierer, N., Fuhrman, J. A., Gallery, R. E., Gevers, D., Gibbs, R. A., San Gil, I., Gonzalez, A., Gordon, J. I., Guralnick, R., Hankeln, W., Highlander, S., Hugenholtz, P., Jansson, J., Kau, A. L., Kelley, S. T., Kennedy, J., Knights, D., Koren, O., Kuczynski, J., Kyrpides, N., Larsen, R., Lauber, C. L., Legg, T., Ley, R. E., Lozupone, C. A., Ludwig, W., Lyons, D., Maguire, E., Methé, B. A., Meyer, F., Muegge, B., Nakielny, S., Nelson, K. E., Nemergut, D., Neufeld, J. D., Newbold, L. K., Oliver, A. E., Pace, N. R., Palanisamy, G., Peplies, J., Petrosino, J., Proctor, L., Pruesse, E., Quast, C., Raes, J., Ratnasingham, S., Ravel, J., Relman, D. A., Assunta-Sansone, S., Schloss, P. D., Schriml, L., Sinha, R., Smith, M. I., Sodergren, E., Spo, A., Stombaugh, J., Tiedje, J. M., Ward, D. V., Weinstock, G. M., Wendel, D., White, O., Whiteley, A., Wilke, A., Wortman, J. R., Yatsunenko, T. & Glöckner, F. O., 2011, In: Nature Biotechnology. 29, 5, p. 415-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Modelling cue integration in cluttered environments

    Sahani, M. & Whiteley, Louise, 2011, Sensory Cue Integration. Trommershäuser, J., Körding, K. & Landy, M. S. (eds.). Oxford University Press, p. 82-100 (Computational Neuroscience).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  73. Published

    Morbidity, including fatal morbidity, throughout life in men entering adult life as obese

    Zimmermann, E., Holst, C. & Sørensen, Thorkild I.A., 2011, In: P L o S One. 6, 4, p. e18546

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome

    Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Kim, S. Y., Korneliussen, Thorfinn Sand, Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Feder, A. F., Grarup, Niels, Jørgensen, T., Jiang, T., Witte, D. R., Sandbæk, A., Hellmann, I., Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: P L o S Genetics. 7, 10, 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Neuroprotective properties of GLP-1: theoretical and practical applications

    Holst, Jens Juul, Burcelin, R. & Nathanson, E., 2011, In: Current Medical Research and Opinion. 27, 3, p. 547-58 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming

    Dominy, J. E., Gerhart-Hines, Zach & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential

    Torekov, Signe Sørensen, Madsbad, Sten & Holst, Jens Juul, 2011, In: Obesity Reviews. 12, 8, p. 593-601 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Obesity research based on the Copenhagen School Health Records Register

    Baker, J. L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. Supplement. 39, 7 Suppl, p. 196-200 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Opportunities for European obesity research in the coming decade - a perspective from the European association for the study of obesity (EASO)

    Oppert, J., Sørensen, Thorkild I.A., Hebebrand, J., Woodward, E. & Blundell, J. E., 2011, In: Obesity Facts. 4, 6, p. 425-6 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change

    Jakobsen, M. U., Dethlefsen, C., Due, K. M., Slimani, N., Chajès, V., May, A. M., Sørensen, T. I. A., Halkjær, J., Tjønneland, A., Clavel-Chapelon, F., Boutron-Ruault, M-C., Fagherazzi, G., Teucher, B., Kaaks, R., Boeing, H., Schütze, M., Trichopoulou, A., Zylis, D., Makrygiannis, G., Palli, D. & 21 others, Mattiello, A., Tagliabue, G., van der, D. L., Bueno-de-Mesquita, H. B., Rodríguez, L., Travier, N., Molina-Montes, E., Huerta, J. M., Barricarte, A., Amiano, P., Manjer, J., Wirfält, E., Johansson, I., Hallmans, G., Khaw, K., Wareham, N. J., Crowe, F., Romieu, I., Riboli, E., Peeters, P. H. M. & Overvad, K., 2011, In: Obesity Facts. 4, 4, p. 312-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Protein dose-response effect on glp-1, pyy and appetite in male subjects

    Sparre, A. B., Sørensen, M. Q., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2011, In: Obesity Reviews. 12, suppl. 1, p. 59 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  82. Published

    Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans

    Nauck, M. A., Kemmeries, G., Holst, Jens Juul & Meier, J. J., 2011, In: Diabetes. 60, 5, p. 1561-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Reversed binding of a small molecule ligand in homologous chemokine receptors – differential role of extracellular loop 2.

    Rummel, P. C., Thiele, S., Steen, A. M. F., Elder, A., Kolbech, R., Ghosh, S., Frimurer, Thomas Michael & Rosenkilde, Mette, 2011, In: British Journal of Pharmacology. 166

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?

    Nauck, M. A., Vardarli, I., Deacon, Carolyn F., Holst, Jens Juul & Meier, J., 2011, In: Diabetologia. 54, 1, p. 10-18 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Short sleep duration as a possible cause of obesity: critical analysis of the epidemiological evidence

    Nielsen, L. S., Danielsen, K. & Sørensen, Thorkild I.A., 2011, In: Obesity Reviews. 12, 2, p. 78-92 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Smallpox vaccination and all-cause infectious disease hospitalization: a Danish register-based cohort study

    Sørup, S., Villumsen, M., Ravn, H., Benn, C. S., Sørensen, Thorkild I.A., Aaby, P., Jess, T. & Roth, A. A. E., 2011, In: International Journal of Epidemiology. 40, 4, p. 955-63 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Studies based on the Danish Adoption Register: schizophrenia, BMI, smoking, and mortality in perspective

    Petersen, L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. 39, 7 Suppl, p. 191-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans

    Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    The Danish Adoption Register

    Petersen, L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. 39, 7 Suppl, p. 83-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

    Grarup, Niels, Overvad, M., Sparsø, T., Witte, D. R., Pisinger, C., Jørgensen, T., Yamauchi, T., Hara, K., Maeda, S., Kadowaki, T., Hansen, T. & Pedersen, Oluf Borbye, 2011, In: Diabetologica. 54, 4, p. 789-94 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

    Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys

    Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans

    Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    The effects of adding group-based lifestyle counselling to individual counselling on changes in plasma glucose levels in a randomized controlled trial: the Inter99 study

    Lau, C., Vistisen, D., Toft, U., Tetens, Inge , Glümer, C., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2011, In: Diabetes & Metabolism. 37, 6, p. 546-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism

    Quistorff, B. & Grunnet, N., 2011, In: Aging. 3, 5, p. 457-460

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

    Lund, Asger Bach, Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 6, p. E1038-E1046 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Three-dimensional reconstructions of intrahepatic bile duct tubulogenesis in human liver

    Vestentoft, P. S., Jelnes, P., Hopkinson, B. M., Vainer, B., Møllgård, Kjeld, Quistorff, B. & Bisgaard, Hanne Cathrine, 2011, In: B M C Developmental Biology. 11, p. 56

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Three-dimensional reconstructions of intrahepatic bile duct tubulogenesis in human liver

    Vestentoft, P. S., Jelnes, P., Hopkinson, B. M., Vainer, B., Møllgård, Kjeld, Quistorff, B. & Bisgaard, Hanne Cathrine, 2011, In: BMC Developmental Biology. 11, p. 56

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Tracking of leptin, soluble leptin receptor, and the free leptin index during weight loss and regain in children

    Holm, J., Gamborg, M., Ward, L. C., Gammeltoft, S., Kaas-Ibsen, K., Heitmann, B. L. & Sørensen, Thorkild I.A., 2011, In: Obesity Facts. 4, 6, p. 461-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Treatments and services for neurodevelopmental disorders on advocacy websites: Information or evaluation?

    Di Pietro, N. C., Whiteley, Louise & Illes, J., 2011, In: Neuroethics. 5, 2, p. 197-209 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Trend in obesity prevalence in European adult cohort populations during follow-up since 1996 and their predictions to 2015

    Ruesten, A. V., Steffen, A., Floegel, A., A, D. L. V. D., Masala, G., Tjønneland, A., Halkjaer, J., Palli, D., Wareham, N. J., Loos, R. J. F., Sørensen, Thorkild I.A. & Boeing, H., 2011, In: P L o S One. 6, 11, p. e27455

    Research output: Contribution to journal › Journal article › Research › peer-review

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