- 2013
- Published
Surgically Induced Interpregnancy Weight Loss and Prevalence of Overweight and Obesity in Offspring
Willmer, M., Berglind, D., Sørensen, Thorkild I.A., Näslund, E., Tynelius, P. & Rasmussen, F., 2013, In: P L o S One. 8, 12, p. 1-7 7 p., e82247.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFAP2B -Dietary Protein and Glycemic Index Interactions and Weight Maintenance after Weight Loss in the DiOGenes Trial
Stocks, T., Ängquist, Lars, Hager, J., Charon, C., Holst, C., Martinez, J. A., Saris, W. H. M., Astrup, A., Sørensen, Thorkild I.A. & Larsen, L. H., 2013, In: Human Heredity. 75, 2-4, p. 213-219 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression
Bjerre, C. A., Jensen, L. V., Belling, K. C., Würtz, S. Ø., Yadav, R., Lademann, U. A., Rigina, O., Do, K. N., Ditzel, H. J., Lykkesfeldt, A. E., Wang, J., Nielsen, H. B., Brünner, N., Gupta, R., Rasmussen, A. S. & Stenvang, Jan, 2013, In: Tumor Biology. 34, 6, p. 3839-3851 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release
Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of Roux-en-Y gastric bypass surgery on energy expenditure and appetite: a randomized human study including “pair fed” control subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S., Nielsen, M. S., Nielsen, L. V., Holst, Jens Juul, Hansen, D. L., Dorm, D. W., Madsbad, Sten, Clausen, T. R. C., Ritz, C., Astrup, A. & Sjödin, Anders Mikael, 2013, In: Obesity Facts. 6, suppl. 1, p. 28 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial
Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of long-term taurine supplementation and fructose feeding on glucose and lipid homeostasis in Wistar rats
Larsen, L. H., Orstrup, L. K. H., Hansen, S. H., Grunnet, N., Quistorff, B. & Mortensen, Ole Hartvig, 2013, In: Advances in Experimental Medicine and Biology. 776, p. 39-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transient activation of mTOR following forced treadmill exercise in rats
Elfving, B., Christensen, T., Ratner, C., Wienecke, Jacob & Klein, A. B., 2013, In: Synapse. 67, 9, p. 620-625 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatments for Neurodevelopmental Disorders: Evidence, Advocacy, and the Internet
Di Pietro, N. C., Whiteley, Louise, Mizgalewicz, A. & Illes, J., 2013, In: Journal of Autism and Developmental Disorders. 43, 1, p. 122-133 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trends in prevalence of overweight and obesity in danish infants, children and adolescents--are we still on a plateau?
Morgen, C. S., Rokholm, B., Sjöberg Brixval, C., Schou Andersen, C., Geisler Andersen, L., Rasmussen, M., Nybo Andersen, Anne-Marie, Due, P. & Sørensen, Thorkild I.A., 2013, In: P L o S One. 8, 7, p. e69860Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two Weeks of Metformin Treatment Induces AMPK Dependent Enhancement of Insulin Stimulated Glucose Transport in Mouse Skeletal Muscle
Kristensen, Jonas Møller, Treebak, Jonas Thue, Goodyear, L. J. & Wojtaszewski, Jørgen F P, 2013, In: Diabetes. 62, Suppl. 1, p. A462 1 p., 1780-P.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Utilizing social media to study information-seeking and ethical issues in gene therapy
Robillard, J. M., Whiteley, Louise, Johnson, T. W., Lim, J., Wasserman, W. W. & Illes, J., 2013, In: Journal of Medical Internet Research. 15, 3, p. e44Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1
Cao, Y., Gao, Z., Li, L., Jiang, X., Shan, A., Cai, J., Peng, Y., Li, Y., Jiang, X., Huang, X., Wang, J., Wei, Q., Qin, G., Zhao, J., Jin, X., Liu, L., Li, Y., Wang, W., Wang, J. & Ning, G., 2013, In: Nature Communications. 4, 6 p., 2810.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression
Tammiste, A., Jiang, T., Fischer, K., Mägi, R., Krjutskov, K., Pettai, K., Esko, T., Li, Y., Tansey, K. E., Carroll, L. S., Uher, R., McGuffin, P., Vosa, U., Tsernikova, N., Saria, A., Ng, P. C., Eller, T., Vasar, V., Nutt, D. J., Maron, E. & 2 others, , 2013, In: Journal of Psychopharmacology. 27, 10, p. 915-920 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
Guo, G., Sun, X., Chen, C., Wu, S., Huang, P., Li, Z., Dean, M., Huang, Y., Jia, W., Zhou, Q., Tang, A., Yang, Z., Li, X., Song, P., Zhao, X., Ye, R., Zhang, S., Lin, Z., Qi, M., Wan, S. & 36 others, , 2013, In: Nature Genetics. 45, 12, p. 1459-1463 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Whole-genome sequences of DA and F344 rats with different susceptibilities to arthritis, autoimmunity, inflammation and cancer
Guo, X., Brenner, M., Zhang, X., Laragione, T., Tai, S., Li, Y., Bu, J., Yin, Y., Shah, A. A., Kwan, K., Li, Y., Wang, J. & Gulko, P. S., 2013, In: Genetics. 194, 4, p. 1017-1028 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
Kan, Z., Zheng, H., Liu, X., Li, S., Barber, T. D., Gong, Z., Gao, H., Hao, K., Willard, M. D., Xu, J., Hauptschein, R., Rejto, P. A., Fernandez, J., Wang, G., Zhang, Q., Wang, B., Chen, R., Wang, J., Lee, N. P., Zhou, W. & 30 others, , 2013, In: Genome Research. 23, p. 1422-1433 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome sequencing reveals untapped genetic potential in Africa's indigenous cereal crop sorghum
Mace, E. S., Tai, S., Gilding, E. K., Li, Y., Prentis, P. J., Bian, L., Campbell, B. C., Hu, W., Innes, D. J., Han, X., Cruickshank, A., Dai, C., Frere, C., Zhang, H., Hunt, C. H., Wang, X., Shatte, T., Wang, M., Su, Z., Li, J. & 4 others, , 2013, In: Nature Communications. 4, 9 p., 2320.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation
Valentin-Hansen, L., Holst, Birgitte, Frimurer, Thomas Michael, Schwartz, Thue W. & Hansen, L. V., 21 Dec 2012, In: Journal of Biological Chemistry. 287, 52, p. 43516-43526 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance
Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., Emanuelli, Brice, Smyth, G., Cinti, S., Newgard, C. B., Gibson, B. W., Larsson, N. & Kahn, C. R., 5 Dec 2012, In: Cell Metabolism. 16, 6, p. 765-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adult glucose metabolism in extremely birthweight-discordant monozygotic twins
Frost, M., Petersen, I., Brixen, K., Beck-Nielsen, H., Holst, Jens Juul, Christiansen, L., Højlund, K. & Christensen, K., Dec 2012, In: Diabetologia. 55, 12, p. 3204-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets
van der Meer, Y., Gerrits, W. J. J., van den Bosch, M., Holst, Jens Juul, Moreto, M., Buurman, W. A., Kulik, W. & van Kempen, T. A. T. G., Dec 2012, In: Journal of Animal Science. 90 Suppl 4, p. 302-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissecting signaling and functions of adhesion G protein-coupled receptors
Araç, D., Aust, G., Calebiro, D., Engel, F. B., Formstone, C., Goffinet, A., Hamann, J., Kittel, R. J., Liebscher, I., Lin, H-H., Monk, K. R., Petrenko, A., Piao, X., Prömel, S., Schiöth, H. B., Schwartz, T. W., Stacey, M., Ushkaryov, Y. A., Wobus, M., Wolfrum, U. & 2 others, , Dec 2012, In: Annals of the New York Academy of Sciences. 1276, p. 1-25 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a common variant of the PCSK2 gene on reduced insulin secretion
Jonsson, Anna Elisabet, Isomaa, B., Tuomi, T., Eriksson, J. G., Groop, L. & Lyssenko, V., Dec 2012, In: Diabetologia. 55, 12, p. 3245-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity
Solomon, T. P. J., Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul & Pedersen, Bente Klarlund, Dec 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4682-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia
Gejl, M., Egefjord, L., Lerche, S., Vang, K., Bibby, B. M., Holst, Jens Juul, Mengel, A., Møller, N., Rungby, J., Brock, B. & Gjedde, Albert, Dec 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 12, p. 2146-2152 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves
Taylor-Edwards, C. C., Burrin, D. G., Kristensen, N. B., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., Dec 2012, In: Animal. 6, 12, p. 1985-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)
Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice
Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase
Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zeqiraj, E., Turk, B. E. & Sakamoto, Kei, 1 Nov 2012, In: Cellular Signalling. 24, 11, p. 2085-2094 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. A. & Heise, T., Nov 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)
Benned-Jensen, T., Norn, C., Laurent, S., Madsen, C. M., Larsen, H. M., Arfelt, K. N., Wolf, R. M., Frimurer, Thomas Michael, Sailer, A. W. & Rosenkilde, Mette, 12 Oct 2012, In: The Journal of Biological Chemistry. 287, 42, p. 35470-83 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells
Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery
Bryant, E. J., King, N. A., Falkén, Y., Hellström, P. M., Holst, Jens Juul, Blundell, J. E. & Näslund, E., 12 Oct 2012, In: Surgery for Obesity and Related Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of an Osteopontin gene promoter polymorphism with susceptibility to diabetic nephropathy in Asian Indians
Cheema, B. S., Iyengar, S., Ahluwalia, Tarun Veer Singh, Kohli, H. S., Sharma, R., Shah, V. N., Bhansali, A., Sakhuja, V. & Khullar, M., 9 Oct 2012, In: Clinica chimica acta; international journal of clinical chemistry. 413, 19-20, p. 1600-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational design of conformationally constrained cyclopentapeptide antagonists for C-x-C chemokine receptor 4 (CXCR4)
Mungalpara, J., Thiele, S., Eriksen, Ø., Eksteen, J., Rosenkilde, Mette & Våbenø, J., 9 Oct 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10287-10291 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection
Ekholm, E., Shaat, N. & Holst, Jens Juul, Oct 2012, In: Acta Diabetologica. 49, 5, p. 349-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol
Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
miRSeqNovel: an R based workflow for analyzing miRNA sequencing data
Qian, K., Auvinen, E., Greco, D. & Auvinen, P., Oct 2012, In: Molecular and Cellular Probes. 26, 5, p. 208-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors
Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses
Procaccini, C., De Rosa, V., Galgani, M., Carbone, F., Cassano, S., Greco, D., Qian, K., Auvinen, P., Calì, G., Stallone, G., Formisano, L., La Cava, A. & Matarese, G., 15 Sep 2012, In: Journal of Immunology. 189, 6, p. 2941-53 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor
Hansen, L. V., Groenen, M., Nygaard, R., Frimurer, Thomas Michael, Holliday, N. D. & Schwartz, Thue W., 14 Sep 2012, In: Journal of Biological Chemistry. 287, 38, p. 31973-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor
Els, S., Schild, E., Petersen, P. S., Kilian, T., Mokrosinski, J., Frimurer, Thomas Michael, Chollet, C., Schwartz, Thue W., Holst, Birgitte & Beck-Sickinger, A. G., 13 Sep 2012, In: Journal of Medicinal Chemistry. 55, 17, p. 7437-49 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A metabolic prosurvival role for PML in breast cancer
Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure
Brinkman, A. S., Murali, S. G., Hitt, S., Solverson, P. M., Holst, Jens Juul & Ney, D. M., 1 Sep 2012, In: A J P: Gastrointestinal and Liver Physiology (Online). 303, 5, p. G610-22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs
Stoll, B., Puiman, P. J., Cui, L., Chang, X., Benight, N. M., Bauchart-Thevret, C., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 538-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model
Barnes, J. L., Hartmann, Bolette, Holst, Jens Juul & Tappenden, K. A., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 524-37 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, D. G. R. A. M. (. C., Sep 2012, In: Nature Genetics. 44, 9, p. 991-1005 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
5500
downloads
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5253
downloads
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
4540
downloads
The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
Research output: Contribution to journal › Journal article › Research › peer-review
The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
Research output: Contribution to journal › Journal article › Research › peer-review
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Research output: Contribution to journal › Journal article › Research › peer-review