- 2009
- Published
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index.
Huth, C., Illig, T., Herder, C., Gieger, C., Grallert, H., Vollmert, C., Rathmann, W., Hamid, Y., Pedersen, O., Hansen, T., Thorand, B., Meisinger, C., Doring, A., Klopp, N., Gohlke, H., Lieb, W., Hengstenberg, C., Lyssenko, V., Groop, L., Ireland, H. & 16 others, , 2009, In: Annals of Medicine. 41, p. 128-38Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index
Huth, C., Illig, T., Herder, C., Gieger, C., Grallert, H., Vollmert, C., Rathmann, W., Hamid, Y. H., Pedersen, O., Hansen, T., Thorand, B., Meisinger, C., Doring, A., Klopp, N., Gohlke, H., Lieb, W., Hengstenberg, C., Lyssenko, V., Groop, L., Ireland, H. & 16 others, , 2009, In: Annals of Medicine. 41, 2, p. 128-138 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats
Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longitudinal Analysis of Leptin Variation during Weight Regain after Weight Loss in Obese Children
Holm, Jens-Christian, Gamborg, Michael Orland, Leigh, W., Kaas, I. K., Ibsen, G., Sørensen, Thorkild I.A., Lilienthal, H. B., Holm, Jens-Christian, Gamborg, M., Ward, L., Ibsen, K. K., Gammeltoft, S., Sørensen, Thorkild I.A. & Heitmann, B. L., 2009, In: Obesity Facts. 2, 4, p. 243-248 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial function in lamb as a consequence of maternal caloric restriction during pregnancy and high-fat-high-carbohydrate diet post partem
Jørgensen, W., Nielsen, M. O., Gam, C., Scheibye-Knudsen, M., Grunnet, N. & Quistorff, B., 2009, In: Journal of Diabetes. 1, Suppl. 1, p. A81 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes
Torsvik, J., Johansson, S., Johansen, A., Ek, J., Minton, J., Raeder, H., Ellard, S., Hattersley, A., Pedersen, Oluf Borbye, Hansen, T., Molven, A. & Njølstad, P. R., 2009, In: Human Genetics. 127, 1, p. 55-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult Danes
Gjesing, A. P., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Hansen, T. & Olsen, N. V., 2009, In: PLoS ONE. 4, 9, p. e7206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Past and current body size affect validity of reported energy intake among middle-aged Danish men
Nielsen, B. M., Nielsen, M. M., Toubro, S., Pedersen, Oluf Borbye, Astrup, A., Sørensen, Thorkild I.A., Jess, T. & Heitmann, B. L., 2009, In: Journal of Nutrition. 139, 12, p. 2337-2343 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes
Kring, S. I. I., Werge, Thomas, Holst, C., Toubro, S., Astrup, A., Hansen, Torben, Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2009, In: PLoS ONE. 4, 8, p. e6696 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictive performance for population models using stochastic differential equations applied on data from an oral glucose tolerance test
Møller, J. B., Overgaard, R. V., Madsen, H., Hansen, T., Pedersen, Oluf Borbye & Ingwersen, S. H., 2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 37, 1, p. 85-98 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictors of future fasting and 2-h post-OGTT plasma glucose levels in middle-aged men and women-the Inter99 study
Faerch, K., Vaag, Allan, Witte, D. R., Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetic Medicine. 26, 4, p. 377-83 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Progression to impaired glucose regulation and diabetes in the population-based Inter99 study
Engberg, S., Vistisen, D., Lau, C., Glümer, C., Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetes Care. 32, p. 606-11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spaedbørnsdiabetes kan ofte behandles med sulfonylurinstof i stedet for insulin
Lauridsen, M. H., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T. & Hertz, B., 2009, In: Ugeskrift for læger. 171, 23, p. 1923-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes
Andreasen, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Almind, K., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: BMC Medical Genetics. 10, 1, p. 17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
Holmkvist, J., Banasik, K., Andersen, G., Unoki, H., Jensen, T. S., Pisinger, C., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Brunak, Søren, Maeda, S., Hansen, T. & Pedersen, Oluf Borbye, 2009, In: PLoS ONE. 4, 6, p. e5872Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99)
Urdea, M., Kolberg, J., Wilber, J., Gerwien, R., Moler, E., Rowe, M., Jorgensen, P., Hansen, T., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2009, In: Journal of Diabetes Science and Technology. 3, 4, p. 748-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study
Boesgaard, T. W., Gjesing, A. P., Grarup, N., Rutanen, J., Jansson, P., Hribal, M. L., Sesti, G., Fritsche, A., Stefan, N., Staiger, H., Häring, H., Smith, U., Laakso, M., Pedersen, Oluf Borbye, Hansen, T. & EUGENE2 Consortium, E. C., 2009, In: PLoS ONE. 4, 9, p. e7236Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes
Zobel, D. P., Andreasen, C. H., Grarup, N., Eiberg, Hans Rudolf Lytchoff, Sørensen, Thorkild I.A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2009, In: Diabetes. p. 757-764 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits
Rathcke, C. N., Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 2009, In: PLoS ONE. 4, 5, p. e5469Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the gene encoding Kruppel-like factor 7 influences body fat: studies of 14,818 Danes
Zobel, D., Andreasen, C., Burgdorf, K., Andersson, E., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Maeda, S., Nakamura, Y., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: European Journal of Endocrinology. 160, 4, p. 603-9Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
SOCS-1 deficiency does not prevent diet-induced insulin resistance
Emanuelli, Brice, Macotela, Y., Boucher, J. & Ronald Kahn, C., 12 Dec 2008, In: Biochemical and Biophysical Research Communications. 377, 2, p. 447-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The search for putative unifying genetic factors for components of the metabolic syndrome
Sjögren, M., Lyssenko, V., Jonsson, Anna Elisabet, Berglund, G., Nilsson, P., Groop, L. & Orho-Melander, M., Dec 2008, In: Diabetologia. 51, 12, p. 2242-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical risk factors, DNA variants, and the development of type 2 diabetes
Lyssenko, V., Jonsson, Anna Elisabet, Almgren, P., Pulizzi, N., Isomaa, B., Tuomi, T., Berglund, G., Altshuler, D., Nilsson, P. & Groop, L., 20 Nov 2008, In: New England Journal of Medicine. 359, 21, p. 2220-32 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
Yasuda, K., Miyake, K., Horikawa, Y., Hara, K., Osawa, H., Furuta, H., Hirota, Y., Mori, H., Jonsson, A. E., Sato, Y., Yamagata, K., Hinokio, Y., Wang, H-Y., Tanahashi, T., Nakamura, N., Oka, Y., Iwasaki, N., Iwamoto, Y., Yamada, Y., Seino, Y. & 27 others, , Sep 2008, In: Nature Genetics. 40, 9, p. 1092-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical exercise during pregnancy and the risk of preterm birth: A study within the danish national birth cohort
Juhl, M., Andersen, Per Kragh, Olsen, J., Madsen, M., Jørgensen, Tina, Nøhr, E. A. & Nybo Andersen, Anne-Marie, Aug 2008, In: Obstetrical and Gynecological Survey. 63, 8, p. 495-497 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Strategies for conditional two-locus nonparametric linkage analysis
Ängquist, Lars, Hössjer, O. & Groop, L., 1 Jul 2008, In: Human Heredity. 66, 3, p. 138-156 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial nitric oxide synthase gene haplotypes and diabetic nephropathy among Asian Indians
Ahluwalia, Tarun Veer Singh, Ahuja, M., Rai, T. S., Kohli, H. S., Sud, K., Bhansali, A. & Khullar, M., Jul 2008, In: Molecular and Cellular Biochemistry. 314, 1-2, p. 9-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulinoma in a third-trimester pregnant woman combined with pre-eclampsia: a case report and review of the diagnostic strategies
Christiansen, P. E. & drb459, drb459, Jul 2008, In: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 24, 7, p. 417-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of soy isoflavones on obesity
Ørgaard, A. & Jensen, L., 5 Jun 2008, In: Experimental Biology and Medicine (Maywood). 233, 9, p. 1066-80 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental effects on mortality before age 70 years
Petersen, L., Andersen, Per Kragh, Sørensen, Thorkild I.A., Petersen, L., Andersen, P. K. & Sørensen, Thorkild I.A., 1 May 2008, In: Epidemiology. 19, 3, p. 472-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ACE I/D polymorphism in Indian patients with hypertrophic cardiomyopathy and dilated cardiomyopathy
Rai, T. S., Dhandapany, P. S., Ahluwalia, Tarun Veer Singh, Bhardwaj, M., Bahl, A., Talwar, K. K., Nair, K., Rathinavel, A. & Khullar, M., Apr 2008, In: Molecular and Cellular Biochemistry. 311, 1-2, p. 67-72 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative stress in primary glomerular diseases: a comparative study
Markan, S., Kohli, H. S., Sud, K., Ahuja, M., Ahluwalia, Tarun Veer Singh, Sakhuja, V. & Khullar, M., Apr 2008, In: Molecular and Cellular Biochemistry. 311, 1-2, p. 105-10 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
Gustavsson, N., Lao, Y., Maximov, A., Chuang, J., Kostromina, E., Repa, J. J., Li, C., Radda, G. K., Südhof, T. C. & Han, W., 11 Mar 2008, In: National Academy of Sciences. Proceedings. 105, 10, p. 3992-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance
Emanuelli, Brice, Eberlé, D., Suzuki, R. & Kahn, C. R., 4 Mar 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 9, p. 3545-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of proteomics to study infectious diseases
List, E. O., Berryman, D. E., Bower, B., Sackmann-Sala, L., Gosney, E., Ding, J., Okada, S. & Kopchick, J. J., 1 Mar 2008, In: Infectious Disorders - Drug Targets. 8, 1, p. 31-45 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia
Clausen, Tine Dalsgaard, Mathiesen, E. R., Hansen, T., Pedersen, Oluf Borbye, Jensen, D. M., Lauenborg, J., Damm, Peter, Clausen, T. D., Mathiesen, Elisabeth, Hansen, T., Pedersen, O., Jensen, D., Lauenborg, J. & Damm, Peter, 1 Feb 2008, In: Diabetes Care. 31, 2, p. 340-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic adaptations through the PGC-1α and SIRT1 pathways
Rodgers, J. T., Lerin, C., Gerhart-Hines, Zach & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate
Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In: Pediatrics. 121, 1, p. e180-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Somewhat Subjective Introduction to Gene Mapping through Nonparametric Linkage Analysis
Ängquist, Lars, 2008, Genetic Recombination Research Progress. Schultz, J. H. (ed.). Nova Biomedical Books, 60 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A Unified Discussion on the Concept of Score Functions Used in the Context of Nonparametric Linkage Analysis
Ängquist, Lars, 2008, In: Bioinformatics and Biology Insights. 2, p. 119-132 PMID:19812770.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study
Staiger, H., Stancáková, A., Zilinskaite, J., Vänttinen, M., Hansen, T., Marini, M. A., Hammarstedt, A., Jansson, P., Sesti, G., Smith, U., Pedersen, Oluf Borbye, Laakso, M., Stefan, N., Fritsche, A. & Häring, H., 2008, In: Diabetes. 57, 2, p. 514-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects
Andersen, G., Burgdorf, K. S., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 5, p. 1427-32 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people
Gjesing, A. P., Andersen, G., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Molecular Genetics and Metabolism. 94, 1, p. 90-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: A study of 15,734 Danish subjects
Grarup, N., Stender-Petersen, K. L., Andersson, E. A., Jorgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects
Grarup, N., Stender-Petersen, K. L., Andersson, E. A., Jørgensen, T., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 4, p. 1136-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Grarup, N., Andersen, G., Krarup, N. T., Albrechtsen, Anders, Schmitz, O., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 9, p. 2534-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1
Gonsorcíková, L., Pruhová, S., Cinek, O., Ek, J., Pelikánová, T., Jørgensen, T., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Hansen, T. & Lebl, J., 2008, In: Pediatric Diabetes. 9, 4 Pt 2, p. 367-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common nonsynonymous variants in PCSK1 confer risk of obesity.
Benzinou, M., Creemers, J. W. M., Choquet, H., Lobbens, S., Dina, C., Durand, E., Guerardel, A., Boutin, P., Jouret, B., Heude, B., Balkau, B., Tichet, J., Marre, M., Potoczna, N., Horber, F., Le Stunff, C., Czernichow, S., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K. & 12 others, , 2008, In: Nature Genetics. 40, 8, p. 943-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cost-effectiveness of intensified versus conventional multifactorial intervention in type 2 diabetes: results and projections from the Steno-2 study
Gaede, P., Valentine, W. J., Palmer, A. J., Tucker, D. M. D., Lammert, M., Parving, H. & Pedersen, Oluf Borbye, 2008, In: Diabetes Care. 31, 8, p. 1510-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a multifactorial intervention on mortality in type 2 diabetes
Gaede, P., Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. 358, 6, p. 580-91 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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