Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2024
  2. Accepted/In press

    Effects of exogenous GIP and GLP-2 on bone turnover in individuals with type 2 diabetes

    Skov-Jeppesen, Kirsa, Christiansen, Charlotte Bayer, Hansen, L. S., Windeløv, Johanne Agerlin, Hedbäck, N., Gasbjerg, Lærke Smidt, Hindsø, M., Svane, M. S., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2024, (Accepted/In press) In: The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Atlas of exercise-induced brain activation in mice

    Skovbjerg, G., Fritzen, Andreas Mæchel, Svendsen, C. S. A., Perens, J., Skytte, J. L., Lund, Camilla, Lund, Jens, Madsen, M. R., Roostalu, U., Hecksher-Sørensen, J. & Clemmensen, Christoffer, 2024, In: Molecular Metabolism. 82, 14 p., 101907.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    In Vivo Inhibition of Dipeptidyl Peptidase 4 Allows Measurement of GLP-1 Secretion in Mice

    Smits, Mark, Galsgaard, Katrine Douglas, Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette & Holst, Jens Juul, 2024, In: Diabetes. 73, 5, p. 671-681

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice

    Smits, Mark, Dreyer, S. I. L., Dal, Jenna Elizabeth Hunt, Drzazga, Anna Katarzyna, Modvig, Ida Marie, Holst, Jens Juul & Kissow, Hannelouise, 2024, In: Frontiers in Endocrinology. 15, 1362711.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Development of an automated, high-throughput assay to detect angiotensin AT2-receptor agonistic compounds by nitric oxide measurements in vitro

    Souza-Silva, I. M., Peluso, A. A., Mortensen, C., Nazarova, A. L., Stage, T. B., Sumners, C., Katritch, V. & Steckelings, U. M., 2024, In: Peptides. 172, 7 p., 171137.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

    Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J. & 121 others, Cappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Coutinho de Almeida, R., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Echouffo Tcheugui, J. B., Ellervik, Christina, Eriksson, J. G., Ferrucci, L., Freudenberg, J., Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S. E., Grarup, Niels, Gunjača, I., Hansen, Torben, Harding, B. N., Harris, S. E., Haunsø, Stig, Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, Jørgen K., Kårhus, L. L., Kiemeney, L. A. L. M., Kloppenburg, M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, Allan René, Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Møllehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, Casia, Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, Oluf Borbye, Peters, A., Pietzner, M., Polašek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, Morten Steen Salling, Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sørensen, Thorkild I.A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., van den Akker, E. B., van den Eynde, T., van der Klauw, M. M., van Heemst, D., Verroken, C., Visser, W. E., Vojinovic, D., Völzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H. J. C. M., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zöllner, S., Smit, J. W. A., Peeters, R. P., Köttgen, A., Teumer, A. & Medici, M., 2024, In: Nature Communications. 15, 1, 18 p., 888.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Altered Glucagon and GLP-1 Responses to Oral Glucose in Children and Adolescents With Obesity and Insulin Resistance

    Stinson, Sara, Fernández de Retana Alzola, I., Hovendal, Emilie Damgaard Brünner, Lund, Morten Asp Vonsild, Fonvig, Cilius Esmann, Holm, Louise Aas, Jonsson, Anna Elisabet, Frithioff-Bøjsøe, C., Christiansen, Michael, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, T. I. A., Holst, Jens Juul, Hartmann, Bolette, Holm, Jens-Christian & Hansen, Torben, 2024, In: The Journal of clinical endocrinology and metabolism. 109, 6, p. 1590-1600 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect

    Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Accepted/In press

    Genetic underpinnings of fasting and oral glucose-stimulated based insulin sensitivity indices

    Suleman, Sufyan, Madsen, Anne Lundager, Ängquist, Lars, Schubert, Mikkel, Linneberg, Allan René, Loos, Ruth, Hansen, Torben & Grarup, Niels, 2024, (Accepted/In press) In: Journal of Clinical Endocrinology and Metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Signs of Glucagon Resistance After a Two-Week Hypercaloric Diet Intervention

    Suppli, M. P., Høgedal, A., Bagger, J. I., Chabanova, E., van Hall, Gerrit, Forman, Julie Lyng, Christensen, Mikkel Bring, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 4, p. 955–967 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

    Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., Rayner, N. W., Bocher, O., Arruda, A. L., Sonehara, K., Namba, S., Lee, S. S. K., Preuss, M. H., Petty, L. E., Schroeder, P., Vanderwerff, B. & 31 others, Kals, M., Bragg, F., Lin, K., Guo, X., Zhang, W., Yao, J., Kim, Y. J., Graff, M., Takeuchi, F., Nano, J., Lamri, A., Nakatochi, M., Moon, S., Scott, R. A., Cook, J. P., Lee, J., Pan, I., Taliun, D., Parra, E. J., Grarup, Niels, Chen, W., Bork-Jensen, J., Islam, M. T., Jørgensen, T., Linneberg, Allan René, Witte, D. R., Lind, L., Hansen, Torben, Pedersen, Oluf Borbye, Loos, Ruth & VA Million Veteran Program, V. M. V. P., 2024, In: Nature. 627, 8003, p. 347-357 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Prognostic Value of Gut Microbe-Generated Metabolite Phenylacetylglutamine in Patients with Heart Failure

    Tang, W. H. W., Nemet, I., Li, X. S., Wu, Y., Haghikia, A., Witkowski, M., Koeth, R. A., Demuth, I., König, M., Steinhagen-Thiessen, E., Bäckhed, F., Fischbach, M. A., Deb, A., Landmesser, U. & Hazen, S. L., 2024, In: European Journal of Heart Failure. 26, 2, p. 233-241

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Plasma metabolites of a healthy lifestyle in relation to mortality and longevity: Four prospective US cohort studies

    Tessier, A. J., Wang, F., Liang, L., Wittenbecher, C., Haslam, D. E., Eliassen, A. H., Tobias, D. K., Li, J., Zeleznik, O. A., Ascherio, A., Sun, Q., Stampfer, M. J., Grodstein, F., Rexrode, K. M., Manson, J. A. E., Balasubramanian, R., Clish, C. B., Martínez-González, M. A., Chavarro, J. E., Hu, F. B. & 1 others, Guasch Ferre, Marta, 2024, In: Med. 5, 3, p. 224-238.e5 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Variants at the Interleukin 1 Gene Locus and Pericarditis

    Thorolfsdottir, R. B., Jonsdottir, A. B., Sveinbjornsson, G., Aegisdottir, H. M., Oddsson, A., Stefansson, O. A., Halldorsson, G. H., Saevarsdottir, S., Thorleifsson, G., Stefansdottir, L., Pedersen, O. B., Sørensen, E., Ghouse, J., Raja, A. A., Zheng, C., Silajdzija, E., Rand, S. A., Erikstrup, C., Ullum, H., Mikkelsen, C. & 26 others, Banasik, Karina, Brunak, Søren, Ivarsdottir, E. V., Sigurdsson, A., Beyter, D., Sturluson, A., Einarsson, H., Tragante, V., Helgason, H., Lund, S. H., Halldorsson, B. V., Sigurpalsdottir, B. D., Olafsson, I., Arnar, D. O., Thorgeirsson, G., Knowlton, K. U., Nadauld, L. D., Gretarsdottir, S., Helgadottir, A., Ostrowski, Sisse Rye, Gudbjartssson, D. F., Jonsdottir, I., Bundgård, Henning, Holm, H., Sulem, P. & Stefansson, K., 2024, In: JAMA Cardiology. 9, 2, p. 165-172 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity

    Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Accepted/In press

    Bitter taste receptors: Key target to understand the effects of polyphenols on glucose and body weight homeostasis. Pathophysiological and pharmacological implications

    Trius-Soler, Marta & Moreno, J. J., 2024, (Accepted/In press) In: Biochemical Pharmacology. 116192.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    High-density lipoprotein functionality, cardiovascular health, and patterns of alcohol consumption: new insights and future perspectives

    Trius-Soler, Marta, Mukamal, K. J. & Guasch Ferre, Marta, 2024, In: Current Opinion in Lipidology. 35, 1, p. 25-32 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b

    Uehara, K., Lee, W. D., Stefkovich, M., Biswas, Dipsikha, Santoleri, D., Whitlock, A. G., Quinn, W., Coopersmith, T., Creasy, K. T., Rader, D. J., Sakamoto, Kei, Rabinowitz, J. D. & Titchenell, P. M., 2024, In: Journal of Clinical Investigation. 134, 7, 13 p., e173782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle

    Voisin, S., Seale, K., Jacques, M., Landen, S., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Coffey, V. G., Thompson, J. L. M., Doering, T. M., Lindholm, M. E., Walsh, C., Davison, G., Irwin, R., McBride, C., Hansson, O., Asplund, O., Heikkinen, A. E., Piirilä, P. & 7 others, Pietiläinen, K. H., Ollikainen, M., Blocquiaux, S., Thomis, M., Dawn, C. K., Sharples, A. P. & Eynon, N., 2024, In: Aging Cell. 23, 1, 15 p., e13859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. E-pub ahead of print

    Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test

    Voldstedlund, Christian T, Sjøberg, K. A., Schlabs, Farina Leonie, Sigvardsen, Casper Møller, Andersen, Nicoline Resen, Holst, Jens Juul, Hartmann, Bolette, Wojtaszewski, Jørgen F P, Kiens, Bente, McConell, G. K. & Richter, Erik A., 2024, (E-pub ahead of print) In: Diabetologia.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Clinical exome sequencing reveals a novel pathogenic variant in KIF12 underlying cholestasis with highly variable phenotypes

    Waheed, N., Waris, R., Naseer, M., Razzaq, A., Suleman, Sufyan & Ullah, A., 2024, In: Clinical Genetics. 105, 1, p. 106-108

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  23. Published

    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

    Welsh, J. A., Goberdhan, D. C. I., O’Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. Ỹ. G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T. & 31 others, Sahoo, S., Torrecilhas, A. C., Zheng, L., Zijlstra, A., Abuelreich, S., Bagabas, R., Bergese, P., Bridges, E. M., Brucale, M., Burger, D., Carney, R. P., Cocucci, E., Crescitelli, R., Hanser, E., Harris, A. L., Haughey, N. J., Benediktsdóttir, B. E., Gargiulo, E., Gori, A., Guo, W., Hufnagel, Antonia Sophie, Di Ianni, E., Jacobsen, Søren, Li, B., Mellergaard, M., Nejsum, P., Nolan, J. P., Østergaard, Ole, Yarani, R., Yin, H. & MISEV Consortium, M. C., 2024, In: Journal of Extracellular Vesicles. 13, 2, 84 p., e12404.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. E-pub ahead of print

    Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study

    Winther-Sørensen, Marie, Garcia, S. L., Bartholdy, Andreas, Ottenheijm, Maud Eline, Banasik, Karina, Brunak, Søren, Sorensen, Charlotte Mehlin, Gluud, Lise Lotte, Knop, Filip Krag, Holst, Jens Juul, Rosenkilde, Mette, Jensen, Majken Karoline & Albrechtsen, Nicolai Jacob Wewer, 6 May 2024, (E-pub ahead of print) In: Diabetologia.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. E-pub ahead of print

    Genetics and diet shape the relationship between islet function and whole-body metabolism

    Yau, B., Madsen, S., Healy, M. E., Cooke, K. C., Fritzen, Andreas Mæchel, Thorius, I. H., Stöckli, J., James, D. E. & Kebede, M. A., 3 Apr 2024, (E-pub ahead of print) In: American journal of physiology. Endocrinology and metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome

    Zhu, J., Eliasen, A. U., Aris, I. M., Stinson, Sara, Holm, Jens-Christian, Hansen, Torben, Hivert, M., Bønnelykke, Klaus, Salem, R. M., Hirschhorn, J. N. & Chan, Y., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 2, p. 380-388

    Research output: Contribution to journal › Journal article › Research › peer-review

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