Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2024
  2. Published

    Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study

    Fabricius, T. W., Verhulst, C. E. M., Kristensen, Peter Lommer, Holst, Jens Juul, Tack, C. J., McCrimmon, R. J., Heller, S. R., Evans, M. L., de Galan, B. E., Pedersen-Bjergaard, Ulrik & Hypo-RESOLVE Consortium, H. C., 2024, In: Acta Diabetologica. 61, 5, p. 623-633

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Development of an automated, high-throughput assay to detect angiotensin AT2-receptor agonistic compounds by nitric oxide measurements in vitro

    Souza-Silva, I. M., Peluso, A. A., Mortensen, C., Nazarova, A. L., Stage, T. B., Sumners, C., Katritch, V. & Steckelings, U. M., 2024, In: Peptides. 172, 7 p., 171137.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Dietary fatty acid composition drives neuroinflammation and impaired behavior in obesity

    Sanchez, C., Colson, C., Gautier, N., Noser, Pascal, Salvi, J., Villet, M., Fleuriot, L., Peltier, C., Schlich, P., Brau, F., Sharif, A., Altıntaş, Ali, Amri, E. Z., Nahon, J. L., Blondeau, N., Benani, A., Barrès, Romain & Rovère, C., 2024, In: Brain, Behavior, and Immunity. 117, p. 330-346 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review

    Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Dietary macronutrient composition impacts gene regulation in adipose tissue

    Farris, K. M., Senior, A. M., Sobreira, D. R., Mitchell, R. M., Weber, Z. T., Ingerslev, L. R., Barrès, Romain, Simpson, S. J., Crean, A. J. & Nobrega, M. A., 2024, In: Communications Biology . 7, 13 p., 194.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Discovering Subgroups of Children With High Mortality in Urban Guinea-Bissau: Exploratory and Validation Cohort Study

    Rieckmann, Andreas, Nielsen, S., Dworzynski, P., Amini, H., Mogensen, S. W., Silva, I. B., Chang, A. Y., Arah, O. A., Samek, W., Rod, Naja Hulvej, Ekstrøm, Claus Thorn, Benn, C. S., Aaby, P. & Fisker, A. B., 2024, In: JMIR Public Health and Surveillance. 10, 16 p., e48060.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Do WHO criteria for gestational diabetes fit a rural population in Tanzania? – A follow-up study assessing mother and child health six years after a pregnancy diagnosed with gestational diabetes

    Eriksen, C. B., Minja, D. T., Christensen, Dirk Lund, Bygbjerg, Ib Christian, Damm, Peter, Schmiegelow, Christentze, Grunnet, Louise Groth & Hjort, Line, 2024, In: Diabetes Research and Clinical Practice. 211, 8 p., 111657.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Effect of a 6-Week Carbohydrate-Reduced High-Protein Diet on Levels of FGF21 and GDF15 in People With Type 2 Diabetes

    Richter, Michael Martin, Thomsen, M. N., Skytte, M. J., Kjeldsen, Sasha Alexandra Sampson, Samkani, A., Frystyk, J., Magkos, Faidon, Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Albrechtsen, Nicolai Jacob Wewer, 2024, In: Journal of the Endocrine Society. 8, 4, 11 p., bvae008.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Effect of resveratrol on insulin action in primary myotubes from lean individuals and individuals with severe obesity

    Park, S., Jevtovic, F., Krassovskaia, P. M., Chaves, A. B., Zheng, D., Treebak, Jonas Thue & Houmard, J. A., 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 3, p. E398-E406 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Effects of 3 months of 10-h per-day time-restricted eating and 3 months of follow-up on bodyweight and cardiometabolic health in Danish individuals at high risk of type 2 diabetes: the RESET single-centre, parallel, superiority, open-label, randomised controlled trial

    Quist, Jonas Salling, Pedersen, H. E., Jensen, M. M., Clemmensen, K. K. B., Bjerre, N., Ekblond, T. S., Uldal, S., Størling, Joachim, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Nyeland, M. E., Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G., Blond, Martin Bæk & Færch, K., 2024, In: The Lancet Healthy Longevity. 5, 5, p. e314-e325 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Accepted/In press

    Effects of exogenous GIP and GLP-2 on bone turnover in individuals with type 2 diabetes

    Skov-Jeppesen, Kirsa, Christiansen, Charlotte Bayer, Hansen, L. S., Windeløv, Johanne Agerlin, Hedbäck, N., Gasbjerg, Lærke Smidt, Hindsø, M., Svane, M. S., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2024, (Accepted/In press) In: The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Elucidating pathways to pediatric obesity: a study evaluating obesity polygenic risk scores related to appetitive traits in children

    Renier, T. J., Yeum, D., Emond, J. A., Lansigan, R. K., Ballarino, G. A., Carlson, D. D., Loos, Ruth & Gilbert-Diamond, D., 2024, In: International Journal of Obesity. 48, p. 71-77

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer

    Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

    Baekdal, M., Nielsen, S. W., Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2024, In: Diabetes Care. 47, 1, p. 71-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancy

    Hjort, Line, Bredgaard, S. S., Manitta, Eleonora, Marques, I., Sørensen, A. E., Martino, D., Grunnet, Louise Groth, Kelstrup, Louise, Houshmand-Oeregaard, A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Olsen, Sjurdur F., Saffery, R., Barrès, Romain, Damm, Peter, Vaag, A. A. & Dalgaard, L. T., 2024, In: Clinical Epigenetics. 16, 1, 15 p., 61.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. E-pub ahead of print

    Estimating causality between smoking and abdominal obesity by Mendelian randomization

    Carrasquilla, Germán D., García Ureña, Mario, Romero Lado, María José & Kilpeläinen, Tuomas O., 2024, (E-pub ahead of print) In: Addiction.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Exercise induces tissue-specific adaptations to enhance cardiometabolic health

    Ashcroft, Stephen Paul, Stocks, Ben Nicholas, Egan, B. & Zierath, Juleen R, 2024, In: Cell Metabolism. 36, 2, p. 278-300

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle

    Voisin, S., Seale, K., Jacques, M., Landen, S., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Coffey, V. G., Thompson, J. L. M., Doering, T. M., Lindholm, M. E., Walsh, C., Davison, G., Irwin, R., McBride, C., Hansson, O., Asplund, O., Heikkinen, A. E., Piirilä, P. & 7 others, Pietiläinen, K. H., Ollikainen, M., Blocquiaux, S., Thomis, M., Dawn, C. K., Sharples, A. P. & Eynon, N., 2024, In: Aging Cell. 23, 1, 15 p., e13859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M

    Dollet, L., Lundell, L. S., Chibalin, A. V., Pendergrast, L. A., Pillon, N. J., Lansbury, Elizabeth Laura, Elmastas, M., Frendo-Cumbo, S., Jalkanen, J., de Castro Barbosa, T., Cervone, D. T., Caidahl, K., Dmytriyeva, O., Deshmukh, Atul Shahaji, Barrès, Romain, Rydén, M., Wallberg-Henriksson, H., Zierath, Juleen R & Krook, A., 2024, In: Cell Reports Medicine. 5, 1, 20 p., 101348.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. E-pub ahead of print

    Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test

    Voldstedlund, Christian T, Sjøberg, K. A., Schlabs, Farina Leonie, Sigvardsen, Casper Møller, Andersen, Nicoline Resen, Holst, Jens Juul, Hartmann, Bolette, Wojtaszewski, Jørgen F P, Kiens, Bente, McConell, G. K. & Richter, Erik A., 2024, (E-pub ahead of print) In: Diabetologia.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Exploratory physiological experiments are not clinical trials

    Richter, Erik A., James, D. E., Kirwan, J. P. & Zierath, Juleen R, 2024, In: Cell Metabolism. 36, 5, p. 882-883

    Research output: Contribution to journal › Letter › Research › peer-review

  23. Published

    Exposure to environmental toxicants is associated with gut microbiome dysbiosis, insulin resistance and obesity

    Sen, P., Fan, Yong, Schlezinger, J. J., Ehrlich, S. D., Webster, T. F., Hyötyläinen, T., Pedersen, Oluf Borbye & Orešič, M., 2024, In: Environment International. 186, 12 p., 108569.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability (FOREVER)—A cohort study in a Danish high street optician setting: Design and methodology

    Freiberg, J., Rovelt, J., Gazzard, G., Cour, M. L., Kolko, M., Torp‐Pedersen, C., Benn, M., Brunak, S., Cour, M. L., Tolstrup, J., Toft‐Petersen, A. P., Burgdorf, K. S., Banasik, K., Chmura, P. J., Freiberg, J., Rovelt, J., Thornit, D. N., Foster, P., Gazzard, G., Crabb, D. P. & 4 others, Viswanathan, A., Barman, Sarah, Owen, C. G. & Rudnicka, A. R., 2024, In: Acta Ophthalmologica. 102, 1, p. 80-90 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. E-pub ahead of print

    Functional genomic screens with death rate analyses reveal mechanisms of drug action

    Honeywell, M. E., Isidor, Marie Sophie, Harper, N. W., Fontana, R. E., Birdsall, G. A., Cruz-Gordillo, P., Porto, S. A., Jerome, M., Fraser, C. S., Sarosiek, K. A., Guertin, D. A., Spinelli, J. B. & Lee, M. J., 2024, (E-pub ahead of print) In: Nature Chemical Biology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    GLP-1R signaling modulates colonic energy metabolism, goblet cell number and survival in the absence of gut microbiota

    Greiner, T. U., Koh, A., Peris, E., Bergentall, M., Johansson, M. E. V., Hansson, G. C., Drucker, D. J. & Bäckhed, F., 2024, In: Molecular Metabolism. 83, 12 p., 101924.

    Research output: Contribution to journal › Journal article › Research › peer-review

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