A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. / Jonsson, Anna Elisabet; Isomaa, Bo; Tuomi, Tiinamaija; Taneera, Jalal; Salehi, Albert; Nilsson, Peter; Groop, Leif; Lyssenko, Valeriya.

In: Diabetes, Vol. 58, No. 10, 10.2009, p. 2409-13.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Jonsson, AE, Isomaa, B, Tuomi, T, Taneera, J, Salehi, A, Nilsson, P, Groop, L & Lyssenko, V 2009, 'A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion', Diabetes, vol. 58, no. 10, pp. 2409-13. https://doi.org/10.2337/db09-0246

APA

Jonsson, A. E., Isomaa, B., Tuomi, T., Taneera, J., Salehi, A., Nilsson, P., Groop, L., & Lyssenko, V. (2009). A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes, 58(10), 2409-13. https://doi.org/10.2337/db09-0246

Vancouver

Jonsson AE, Isomaa B, Tuomi T, Taneera J, Salehi A, Nilsson P et al. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. Diabetes. 2009 Oct;58(10):2409-13. https://doi.org/10.2337/db09-0246

Author

Jonsson, Anna Elisabet ; Isomaa, Bo ; Tuomi, Tiinamaija ; Taneera, Jalal ; Salehi, Albert ; Nilsson, Peter ; Groop, Leif ; Lyssenko, Valeriya. / A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion. In: Diabetes. 2009 ; Vol. 58, No. 10. pp. 2409-13.

Bibtex

@article{56b036a6123c4248bd718bd6a2509057,
title = "A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion",
abstract = "Two independent genome-wide association studies for type 2 diabetes in Japanese subjects have recently identified common variants in the KCNQ1 gene that are strongly associated with type 2 diabetes. Here we studied whether a common variant in KCNQ1 would influence BMI as well as insulin secretion and action and predict future type 2 diabetes in subjects from Sweden and Finland.",
keywords = "Body Mass Index, Cadaver, Diabetes Mellitus, Type 2, Female, Finland, Genetic Variation, Genotype, Glucose, Humans, Insulin, Islets of Langerhans, Japan, KCNQ1 Potassium Channel, Male, Predictive Value of Tests, Reference Values, Sweden",
author = "Jonsson, {Anna Elisabet} and Bo Isomaa and Tiinamaija Tuomi and Jalal Taneera and Albert Salehi and Peter Nilsson and Leif Groop and Valeriya Lyssenko",
year = "2009",
month = oct,
doi = "10.2337/db09-0246",
language = "English",
volume = "58",
pages = "2409--13",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association",
number = "10",

}

RIS

TY - JOUR

T1 - A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

AU - Jonsson, Anna Elisabet

AU - Isomaa, Bo

AU - Tuomi, Tiinamaija

AU - Taneera, Jalal

AU - Salehi, Albert

AU - Nilsson, Peter

AU - Groop, Leif

AU - Lyssenko, Valeriya

PY - 2009/10

Y1 - 2009/10

N2 - Two independent genome-wide association studies for type 2 diabetes in Japanese subjects have recently identified common variants in the KCNQ1 gene that are strongly associated with type 2 diabetes. Here we studied whether a common variant in KCNQ1 would influence BMI as well as insulin secretion and action and predict future type 2 diabetes in subjects from Sweden and Finland.

AB - Two independent genome-wide association studies for type 2 diabetes in Japanese subjects have recently identified common variants in the KCNQ1 gene that are strongly associated with type 2 diabetes. Here we studied whether a common variant in KCNQ1 would influence BMI as well as insulin secretion and action and predict future type 2 diabetes in subjects from Sweden and Finland.

KW - Body Mass Index

KW - Cadaver

KW - Diabetes Mellitus, Type 2

KW - Female

KW - Finland

KW - Genetic Variation

KW - Genotype

KW - Glucose

KW - Humans

KW - Insulin

KW - Islets of Langerhans

KW - Japan

KW - KCNQ1 Potassium Channel

KW - Male

KW - Predictive Value of Tests

KW - Reference Values

KW - Sweden

U2 - 10.2337/db09-0246

DO - 10.2337/db09-0246

M3 - Journal article

C2 - 19584308

VL - 58

SP - 2409

EP - 2413

JO - Diabetes

JF - Diabetes

SN - 0012-1797

IS - 10

ER -

ID: 46404349