A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
Research output: Contribution to journal › Journal article › Research › peer-review
Two independent genome-wide association studies for type 2 diabetes in Japanese subjects have recently identified common variants in the KCNQ1 gene that are strongly associated with type 2 diabetes. Here we studied whether a common variant in KCNQ1 would influence BMI as well as insulin secretion and action and predict future type 2 diabetes in subjects from Sweden and Finland.
| Original language | English |
|---|---|
| Journal | Diabetes |
| Volume | 58 |
| Issue number | 10 |
| Pages (from-to) | 2409-13 |
| Number of pages | 5 |
| ISSN | 0046-0192 |
| DOIs | |
| Publication status | Published - Oct 2009 |
- Body Mass Index, Cadaver, Diabetes Mellitus, Type 2, Female, Finland, Genetic Variation, Genotype, Glucose, Humans, Insulin, Islets of Langerhans, Japan, KCNQ1 Potassium Channel, Male, Predictive Value of Tests, Reference Values, Sweden
Research areas
ID: 46404349