Change in body mass index from childhood onwards and risk of adult cardiovascular disease
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Change in body mass index from childhood onwards and risk of adult cardiovascular disease. / Bjerregaard, Lise G.; Adelborg, Kasper; Baker, Jennifer L.
In: Trends in Cardiovascular Medicine, Vol. 30, No. 1, 2020, p. 39-45.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Change in body mass index from childhood onwards and risk of adult cardiovascular disease
AU - Bjerregaard, Lise G.
AU - Adelborg, Kasper
AU - Baker, Jennifer L.
PY - 2020
Y1 - 2020
N2 - Childhood obesity adversely affects the structure and function of the cardiovascular system, but the relationship between excessive weight gain during childhood and adult cardiovascular disease (CVD) is not fully understood. This review summarizes evidence for associations of change in body mass index (BMI) from childhood onwards with CVD outcomes. We found that excessive gain in BMI from childhood onwards was consistently associated with the presence of CVD risk factors, with increased risks of coronary heart disease, and there were suggestions of associations with stroke, atrial fibrillation and heart failure, but a lack of evidence precludes firm conclusions. These results indicate that the risk of CVD can be traced back to child ages and highlights the importance of primordial prevention of CVD by preventing excessive weight gain in childhood. (c) 2019 Elsevier Inc. All rights reserved.
AB - Childhood obesity adversely affects the structure and function of the cardiovascular system, but the relationship between excessive weight gain during childhood and adult cardiovascular disease (CVD) is not fully understood. This review summarizes evidence for associations of change in body mass index (BMI) from childhood onwards with CVD outcomes. We found that excessive gain in BMI from childhood onwards was consistently associated with the presence of CVD risk factors, with increased risks of coronary heart disease, and there were suggestions of associations with stroke, atrial fibrillation and heart failure, but a lack of evidence precludes firm conclusions. These results indicate that the risk of CVD can be traced back to child ages and highlights the importance of primordial prevention of CVD by preventing excessive weight gain in childhood. (c) 2019 Elsevier Inc. All rights reserved.
KW - Body mass index
KW - Cardiovascular disease
KW - Children
KW - Growth
KW - Obesity
KW - Overweight
KW - CORONARY-HEART-DISEASE
KW - BLOOD-PRESSURE
KW - BMI INCREASE
KW - YOUNG-ADULTS
KW - LATER LIFE
KW - OBESITY
KW - GROWTH
KW - MORBIDITY
KW - TRACKING
KW - WEIGHT
U2 - 10.1016/j.tcm.2019.01.011
DO - 10.1016/j.tcm.2019.01.011
M3 - Review
C2 - 30772134
VL - 30
SP - 39
EP - 45
JO - Trends in Cardiovascular Medicine
JF - Trends in Cardiovascular Medicine
SN - 1050-1738
IS - 1
ER -
ID: 250601028