Effect of antibiotics on gut microbiota, glucose metabolism and bodyweight regulation: a review of the literature
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Effect of antibiotics on gut microbiota, glucose metabolism and bodyweight regulation : a review of the literature. / Mikkelsen, Kristian Hallundbaek; Allin, Kristine Højgaard; Knop, Filip Krag.
In: Diabetes, Obesity and Metabolism, Vol. 18, No. 5, 444–453, 05.2016.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Effect of antibiotics on gut microbiota, glucose metabolism and bodyweight regulation
T2 - a review of the literature
AU - Mikkelsen, Kristian Hallundbaek
AU - Allin, Kristine Højgaard
AU - Knop, Filip Krag
N1 - This article is protected by copyright. All rights reserved.
PY - 2016/5
Y1 - 2016/5
N2 - Gut bacteria are involved in a number of host metabolic processes and have been implicated in the development of obesity and type 2 diabetes in humans. Use of antibiotics changes the composition of the gut microbiota and there is accumulating evidence from observational studies for an association between exposure to antibiotics and development of obesity and type 2 diabetes. Here we review human studies examining effects of antibiotics on bodyweight regulation and glucose metabolism and discuss whether the observed findings may relate to alterations in the composition and function of the gut microbiota.
AB - Gut bacteria are involved in a number of host metabolic processes and have been implicated in the development of obesity and type 2 diabetes in humans. Use of antibiotics changes the composition of the gut microbiota and there is accumulating evidence from observational studies for an association between exposure to antibiotics and development of obesity and type 2 diabetes. Here we review human studies examining effects of antibiotics on bodyweight regulation and glucose metabolism and discuss whether the observed findings may relate to alterations in the composition and function of the gut microbiota.
U2 - 10.1111/dom.12637
DO - 10.1111/dom.12637
M3 - Review
C2 - 26818734
VL - 18
JO - Diabetes, Obesity and Metabolism
JF - Diabetes, Obesity and Metabolism
SN - 1462-8902
IS - 5
M1 - 444–453
ER -
ID: 156084726