Epigenetisk påvirkning af fosterets udvikling
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Epigenetisk påvirkning af fosterets udvikling. / Donkin, Ida; Barrès, Romain; Pinborg, Anja.
In: Ugeskrift for Laeger, Vol. 178, No. 37, V02160132, 12.09.2016, p. 2-5.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Epigenetisk påvirkning af fosterets udvikling
AU - Donkin, Ida
AU - Barrès, Romain
AU - Pinborg, Anja
PY - 2016/9/12
Y1 - 2016/9/12
N2 - The epigenome is sensitive to environmental changes and can sustainably alter gene expression, notably during embryonic development. New research indicates that epigenetic factors are heritable, which is why paternal lifestyle may affect fetal development and risk of disease. Children conceived by assisted reproduction technology (ART) have an increased risk of peri- and postnatal complications, and as specific ART protocols associate with specific risk profiles, the procedures themselves may cause epigenetic changes contributing to the altered outcomes of the 5,000 Danish children annually conceived by ART.
AB - The epigenome is sensitive to environmental changes and can sustainably alter gene expression, notably during embryonic development. New research indicates that epigenetic factors are heritable, which is why paternal lifestyle may affect fetal development and risk of disease. Children conceived by assisted reproduction technology (ART) have an increased risk of peri- and postnatal complications, and as specific ART protocols associate with specific risk profiles, the procedures themselves may cause epigenetic changes contributing to the altered outcomes of the 5,000 Danish children annually conceived by ART.
KW - English Abstract
KW - Journal Article
M3 - Tidsskriftartikel
C2 - 27649584
VL - 178
SP - 2
EP - 5
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 37
M1 - V02160132
ER -
ID: 172479012