Genetic predisposition to macronutrient preference and workplace food choices

Research output: Contribution to journal › Review › Research › peer-review

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Genetic predisposition to macronutrient preference and workplace food choices. / Merino, Jordi; Dashti, Hassan S.; Levy, Douglas E.; Del Rocío Sevilla-González, Magdalena; Hivert, Marie France; Porneala, Bianca C.; Saxena, Richa; Thorndike, Anne N.

In: Molecular Psychiatry, Vol. 28, No. 9, 2023, p. 2606–2611.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Merino, J, Dashti, HS, Levy, DE, Del Rocío Sevilla-González, M, Hivert, MF, Porneala, BC, Saxena, R & Thorndike, AN 2023, 'Genetic predisposition to macronutrient preference and workplace food choices', Molecular Psychiatry, vol. 28, no. 9, pp. 2606–2611. https://doi.org/10.1038/s41380-023-02107-x

APA

Merino, J., Dashti, H. S., Levy, D. E., Del Rocío Sevilla-González, M., Hivert, M. F., Porneala, B. C., Saxena, R., & Thorndike, A. N. (2023). Genetic predisposition to macronutrient preference and workplace food choices. Molecular Psychiatry, 28(9), 2606–2611. https://doi.org/10.1038/s41380-023-02107-x

Vancouver

Merino J, Dashti HS, Levy DE, Del Rocío Sevilla-González M, Hivert MF, Porneala BC et al. Genetic predisposition to macronutrient preference and workplace food choices. Molecular Psychiatry. 2023;28(9):2606–2611. https://doi.org/10.1038/s41380-023-02107-x

Author

Merino, Jordi ; Dashti, Hassan S. ; Levy, Douglas E. ; Del Rocío Sevilla-González, Magdalena ; Hivert, Marie France ; Porneala, Bianca C. ; Saxena, Richa ; Thorndike, Anne N. / Genetic predisposition to macronutrient preference and workplace food choices. In: Molecular Psychiatry. 2023 ; Vol. 28, No. 9. pp. 2606–2611.

Bibtex

@article{9c8e56d79abf47dc8f9ca5b97ab32ce9,
title = "Genetic predisposition to macronutrient preference and workplace food choices",
abstract = "Prior research identified genetic variants influencing macronutrient preference, but whether genetic differences underlying nutrient preference affect long-term food choices is unknown. Here we examined the associations of polygenic scores for carbohydrate, fat, and protein preference with 12 months{\textquoteright} workplace food purchases among 397 hospital employees from the ChooseWell 365 study. Food purchases were obtained retrospectively from the hospital{\textquoteright}s cafeteria sales data for the 12 months before participants were enrolled in the ChooseWell 365 study. Traffic light labels, visible to employees when making purchases, measured the quality of workplace purchases. During the 12-month study period, there were 215,692 cafeteria purchases. Each SD increase in the polygenic score for carbohydrate preference was associated with 2.3 additional purchases/month (95%CI, 0.2 to 4.3; p = 0.03) and a higher number of green-labeled purchases (β = 1.9, 95%CI, 0.5–3.3; p = 0.01). These associations were consistent in subgroup and sensitivity analyses accounting for additional sources of bias. There was no evidence of associations between fat and protein polygenic scores and cafeteria purchases. Findings from this study suggest that genetic differences in carbohydrate preference could influence long-term workplace food purchases and may inform follow-up experiments to enhance our understanding of the molecular mechanisms underlying food choice behavior.",
author = "Jordi Merino and Dashti, {Hassan S.} and Levy, {Douglas E.} and {Del Roc{\'i}o Sevilla-Gonz{\'a}lez}, Magdalena and Hivert, {Marie France} and Porneala, {Bianca C.} and Richa Saxena and Thorndike, {Anne N.}",
note = "Publisher Copyright: {\textcopyright} 2023, The Author(s), under exclusive licence to Springer Nature Limited.",
year = "2023",
doi = "10.1038/s41380-023-02107-x",
language = "English",
volume = "28",
pages = "2606–2611",
journal = "Molecular Psychiatry",
issn = "1359-4184",
publisher = "nature publishing group",
number = "9",

}

RIS

TY - JOUR

T1 - Genetic predisposition to macronutrient preference and workplace food choices

AU - Merino, Jordi

AU - Dashti, Hassan S.

AU - Levy, Douglas E.

AU - Del Rocío Sevilla-González, Magdalena

AU - Hivert, Marie France

AU - Porneala, Bianca C.

AU - Saxena, Richa

AU - Thorndike, Anne N.

N1 - Publisher Copyright: © 2023, The Author(s), under exclusive licence to Springer Nature Limited.

PY - 2023

Y1 - 2023

N2 - Prior research identified genetic variants influencing macronutrient preference, but whether genetic differences underlying nutrient preference affect long-term food choices is unknown. Here we examined the associations of polygenic scores for carbohydrate, fat, and protein preference with 12 months’ workplace food purchases among 397 hospital employees from the ChooseWell 365 study. Food purchases were obtained retrospectively from the hospital’s cafeteria sales data for the 12 months before participants were enrolled in the ChooseWell 365 study. Traffic light labels, visible to employees when making purchases, measured the quality of workplace purchases. During the 12-month study period, there were 215,692 cafeteria purchases. Each SD increase in the polygenic score for carbohydrate preference was associated with 2.3 additional purchases/month (95%CI, 0.2 to 4.3; p = 0.03) and a higher number of green-labeled purchases (β = 1.9, 95%CI, 0.5–3.3; p = 0.01). These associations were consistent in subgroup and sensitivity analyses accounting for additional sources of bias. There was no evidence of associations between fat and protein polygenic scores and cafeteria purchases. Findings from this study suggest that genetic differences in carbohydrate preference could influence long-term workplace food purchases and may inform follow-up experiments to enhance our understanding of the molecular mechanisms underlying food choice behavior.

AB - Prior research identified genetic variants influencing macronutrient preference, but whether genetic differences underlying nutrient preference affect long-term food choices is unknown. Here we examined the associations of polygenic scores for carbohydrate, fat, and protein preference with 12 months’ workplace food purchases among 397 hospital employees from the ChooseWell 365 study. Food purchases were obtained retrospectively from the hospital’s cafeteria sales data for the 12 months before participants were enrolled in the ChooseWell 365 study. Traffic light labels, visible to employees when making purchases, measured the quality of workplace purchases. During the 12-month study period, there were 215,692 cafeteria purchases. Each SD increase in the polygenic score for carbohydrate preference was associated with 2.3 additional purchases/month (95%CI, 0.2 to 4.3; p = 0.03) and a higher number of green-labeled purchases (β = 1.9, 95%CI, 0.5–3.3; p = 0.01). These associations were consistent in subgroup and sensitivity analyses accounting for additional sources of bias. There was no evidence of associations between fat and protein polygenic scores and cafeteria purchases. Findings from this study suggest that genetic differences in carbohydrate preference could influence long-term workplace food purchases and may inform follow-up experiments to enhance our understanding of the molecular mechanisms underlying food choice behavior.

U2 - 10.1038/s41380-023-02107-x

DO - 10.1038/s41380-023-02107-x

M3 - Review

C2 - 37217678

AN - SCOPUS:85160025155

VL - 28

SP - 2606

EP - 2611

JO - Molecular Psychiatry

JF - Molecular Psychiatry

SN - 1359-4184

IS - 9

ER -

ID: 348166955