Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life. / Bjerregaard, Lise G; Jensen, Britt W; Baker, Jennifer L.

In: Paediatric and Perinatal Epidemiology, Vol. 31, No. 4, 07.2017, p. 284-292.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bjerregaard, LG, Jensen, BW & Baker, JL 2017, 'Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life', Paediatric and Perinatal Epidemiology, vol. 31, no. 4, pp. 284-292. https://doi.org/10.1111/ppe.12366

APA

Bjerregaard, L. G., Jensen, B. W., & Baker, J. L. (2017). Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life. Paediatric and Perinatal Epidemiology, 31(4), 284-292. https://doi.org/10.1111/ppe.12366

Vancouver

Bjerregaard LG, Jensen BW, Baker JL. Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life. Paediatric and Perinatal Epidemiology. 2017 Jul;31(4):284-292. https://doi.org/10.1111/ppe.12366

Author

Bjerregaard, Lise G ; Jensen, Britt W ; Baker, Jennifer L. / Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life. In: Paediatric and Perinatal Epidemiology. 2017 ; Vol. 31, No. 4. pp. 284-292.

Bibtex

@article{b477f27087034c35a20f7c898b68d290,
title = "Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life",
abstract = "BACKGROUND: Short adults have an increased risk of type 2 diabetes. Although adult height results from childhood growth, the effects of height and growth trajectories during childhood are sparsely investigated. We investigated sex-specific associations between childhood height, growth and adult type 2 diabetes, including potential influences of birthweight and childhood body mass index (BMI).METHODS: We followed 292 827 individuals, born 1930-83, from the Copenhagen School Health Records Register in national registers for type 2 diabetes (11 548 men; 7472 women). Weights and heights were measured at ages 7-13 years. Hazard ratios (HR) of type 2 diabetes (age ≥30 years) were estimated without and with adjustment for birthweight and BMI.RESULTS: In men, associations between height and type 2 diabetes changed from inverse for below-average heights at age 7 years to positive for above-average heights at 13 years. No consistent associations were observed among women. These associations were not affected by birthweight. After adjustment for BMI, below-average childhood heights were inversely associated with type 2 diabetes among men (HR range: 0.91-0.93 per z-score) but above-average heights were not. Among women, after adjustment for BMI, below- and above-average heights in childhood were inversely associated with type 2 diabetes (HR range: 0.91-0.95). Greater height growth from 7 to 13 years was positively associated with type 2 diabetes in men and women.CONCLUSIONS: After adjustment for BMI, short childhood height at all ages and greater growth during childhood are associated with an increased risk of type 2 diabetes, suggesting that this period of life warrants mechanistic investigations.",
keywords = "Journal Article",
author = "Bjerregaard, {Lise G} and Jensen, {Britt W} and Baker, {Jennifer L}",
note = "{\textcopyright} 2017 John Wiley & Sons Ltd.",
year = "2017",
month = jul,
doi = "10.1111/ppe.12366",
language = "English",
volume = "31",
pages = "284--292",
journal = "Paediatric and Perinatal Epidemiology",
issn = "0269-5022",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life

AU - Bjerregaard, Lise G

AU - Jensen, Britt W

AU - Baker, Jennifer L

N1 - © 2017 John Wiley & Sons Ltd.

PY - 2017/7

Y1 - 2017/7

N2 - BACKGROUND: Short adults have an increased risk of type 2 diabetes. Although adult height results from childhood growth, the effects of height and growth trajectories during childhood are sparsely investigated. We investigated sex-specific associations between childhood height, growth and adult type 2 diabetes, including potential influences of birthweight and childhood body mass index (BMI).METHODS: We followed 292 827 individuals, born 1930-83, from the Copenhagen School Health Records Register in national registers for type 2 diabetes (11 548 men; 7472 women). Weights and heights were measured at ages 7-13 years. Hazard ratios (HR) of type 2 diabetes (age ≥30 years) were estimated without and with adjustment for birthweight and BMI.RESULTS: In men, associations between height and type 2 diabetes changed from inverse for below-average heights at age 7 years to positive for above-average heights at 13 years. No consistent associations were observed among women. These associations were not affected by birthweight. After adjustment for BMI, below-average childhood heights were inversely associated with type 2 diabetes among men (HR range: 0.91-0.93 per z-score) but above-average heights were not. Among women, after adjustment for BMI, below- and above-average heights in childhood were inversely associated with type 2 diabetes (HR range: 0.91-0.95). Greater height growth from 7 to 13 years was positively associated with type 2 diabetes in men and women.CONCLUSIONS: After adjustment for BMI, short childhood height at all ages and greater growth during childhood are associated with an increased risk of type 2 diabetes, suggesting that this period of life warrants mechanistic investigations.

AB - BACKGROUND: Short adults have an increased risk of type 2 diabetes. Although adult height results from childhood growth, the effects of height and growth trajectories during childhood are sparsely investigated. We investigated sex-specific associations between childhood height, growth and adult type 2 diabetes, including potential influences of birthweight and childhood body mass index (BMI).METHODS: We followed 292 827 individuals, born 1930-83, from the Copenhagen School Health Records Register in national registers for type 2 diabetes (11 548 men; 7472 women). Weights and heights were measured at ages 7-13 years. Hazard ratios (HR) of type 2 diabetes (age ≥30 years) were estimated without and with adjustment for birthweight and BMI.RESULTS: In men, associations between height and type 2 diabetes changed from inverse for below-average heights at age 7 years to positive for above-average heights at 13 years. No consistent associations were observed among women. These associations were not affected by birthweight. After adjustment for BMI, below-average childhood heights were inversely associated with type 2 diabetes among men (HR range: 0.91-0.93 per z-score) but above-average heights were not. Among women, after adjustment for BMI, below- and above-average heights in childhood were inversely associated with type 2 diabetes (HR range: 0.91-0.95). Greater height growth from 7 to 13 years was positively associated with type 2 diabetes in men and women.CONCLUSIONS: After adjustment for BMI, short childhood height at all ages and greater growth during childhood are associated with an increased risk of type 2 diabetes, suggesting that this period of life warrants mechanistic investigations.

KW - Journal Article

U2 - 10.1111/ppe.12366

DO - 10.1111/ppe.12366

M3 - Journal article

C2 - 28590597

VL - 31

SP - 284

EP - 292

JO - Paediatric and Perinatal Epidemiology

JF - Paediatric and Perinatal Epidemiology

SN - 0269-5022

IS - 4

ER -

ID: 182933891