Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants

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Standard

Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants. / Gottschau, A; Hogh, B.

In: Statistics in Medicine, Vol. 14, No. 24, 30.12.1995, p. 2727-36.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gottschau, A & Hogh, B 1995, 'Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants', Statistics in Medicine, vol. 14, no. 24, pp. 2727-36.

APA

Gottschau, A., & Hogh, B. (1995). Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants. Statistics in Medicine, 14(24), 2727-36.

Vancouver

Gottschau A, Hogh B. Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants. Statistics in Medicine. 1995 Dec 30;14(24):2727-36.

Author

Gottschau, A ; Hogh, B. / Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants. In: Statistics in Medicine. 1995 ; Vol. 14, No. 24. pp. 2727-36.

Bibtex

@article{08a57bcf198f431da78772f69ae81b44,
title = "Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants",
abstract = "A statistical model for interval censored data is described. Assuming a piecewise constant incidence enables us to analyse very unbalanced data in a generalized linear model. The distribution of age at first appearance of P. falciparum parasites in infants in Liberia has been estimated. A new graphical method for presentation of test results on all children was developed. In an illness--death model it is described how the proportion of undetected and detected malaria parasitemias depends on parasite rates and testing frequency. The incidence of detectable malaria parasitemia was 0.14 per month in infants under 4 months of age, and 0.60 per month in children over 4 months (p < 0.001). The congenital resistance to malaria in African infants living in a highly endemic area had largely disappeared by the age of 4 months; before this age children were partly protected.",
keywords = "Age Distribution, Bias, Humans, Immunity, Maternally-Acquired, Incidence, Infant, Infant, Newborn, Liberia/epidemiology, Linear Models, Malaria, Falciparum/immunology, Markov Chains, Mass Screening/methods, Seasons, Survival Analysis",
author = "A Gottschau and B Hogh",
year = "1995",
month = dec,
day = "30",
language = "English",
volume = "14",
pages = "2727--36",
journal = "Statistics in Medicine",
issn = "0277-6715",
publisher = "JohnWiley & Sons Ltd",
number = "24",

}

RIS

TY - JOUR

T1 - Interval censored survival data and multistate compartmental models in the analysis of first appearance of Plasmodium falciparum parasites in infants

AU - Gottschau, A

AU - Hogh, B

PY - 1995/12/30

Y1 - 1995/12/30

N2 - A statistical model for interval censored data is described. Assuming a piecewise constant incidence enables us to analyse very unbalanced data in a generalized linear model. The distribution of age at first appearance of P. falciparum parasites in infants in Liberia has been estimated. A new graphical method for presentation of test results on all children was developed. In an illness--death model it is described how the proportion of undetected and detected malaria parasitemias depends on parasite rates and testing frequency. The incidence of detectable malaria parasitemia was 0.14 per month in infants under 4 months of age, and 0.60 per month in children over 4 months (p < 0.001). The congenital resistance to malaria in African infants living in a highly endemic area had largely disappeared by the age of 4 months; before this age children were partly protected.

AB - A statistical model for interval censored data is described. Assuming a piecewise constant incidence enables us to analyse very unbalanced data in a generalized linear model. The distribution of age at first appearance of P. falciparum parasites in infants in Liberia has been estimated. A new graphical method for presentation of test results on all children was developed. In an illness--death model it is described how the proportion of undetected and detected malaria parasitemias depends on parasite rates and testing frequency. The incidence of detectable malaria parasitemia was 0.14 per month in infants under 4 months of age, and 0.60 per month in children over 4 months (p < 0.001). The congenital resistance to malaria in African infants living in a highly endemic area had largely disappeared by the age of 4 months; before this age children were partly protected.

KW - Age Distribution

KW - Bias

KW - Humans

KW - Immunity, Maternally-Acquired

KW - Incidence

KW - Infant

KW - Infant, Newborn

KW - Liberia/epidemiology

KW - Linear Models

KW - Malaria, Falciparum/immunology

KW - Markov Chains

KW - Mass Screening/methods

KW - Seasons

KW - Survival Analysis

M3 - Journal article

C2 - 8619111

VL - 14

SP - 2727

EP - 2736

JO - Statistics in Medicine

JF - Statistics in Medicine

SN - 0277-6715

IS - 24

ER -

ID: 202982319