Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes : Findings From Two Large Prospective Cohorts. / Birukov, Anna; Guasch-Ferré, Marta; Ley, Sylvia H; Tobias, Deirdre K; Wang, Fenglei; Wittenbecher, Clemens; Yang, Jiaxi; Manson, JoAnn E; Chavarro, Jorge E; Hu, Frank B; Zhang, Cuilin.

In: Diabetes Care, Vol. 47, No. 4, 2024, p. 720-728.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Birukov, A, Guasch-Ferré, M, Ley, SH, Tobias, DK, Wang, F, Wittenbecher, C, Yang, J, Manson, JE, Chavarro, JE, Hu, FB & Zhang, C 2024, 'Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts', Diabetes Care, vol. 47, no. 4, pp. 720-728. https://doi.org/10.2337/dc23-1494

APA

Birukov, A., Guasch-Ferré, M., Ley, S. H., Tobias, D. K., Wang, F., Wittenbecher, C., Yang, J., Manson, J. E., Chavarro, J. E., Hu, F. B., & Zhang, C. (2024). Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts. Diabetes Care, 47(4), 720-728. https://doi.org/10.2337/dc23-1494

Vancouver

Birukov A, Guasch-Ferré M, Ley SH, Tobias DK, Wang F, Wittenbecher C et al. Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts. Diabetes Care. 2024;47(4):720-728. https://doi.org/10.2337/dc23-1494

Author

Birukov, Anna ; Guasch-Ferré, Marta ; Ley, Sylvia H ; Tobias, Deirdre K ; Wang, Fenglei ; Wittenbecher, Clemens ; Yang, Jiaxi ; Manson, JoAnn E ; Chavarro, Jorge E ; Hu, Frank B ; Zhang, Cuilin. / Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes : Findings From Two Large Prospective Cohorts. In: Diabetes Care. 2024 ; Vol. 47, No. 4. pp. 720-728.

Bibtex

@article{6302be58f1e64aa29d99652055c74cf3,
title = "Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts",
abstract = "OBJECTIVE: Breastfeeding duration is inversely associated with risks of cardiovascular disease (CVD) and type 2 diabetes in parous women. However, the association among women at high risk, including women with type 2 diabetes or gestational diabetes mellitus (GDM) is unclear.RESEARCH DESIGN AND METHODS: We included 15,146 parous women with type 2 diabetes from the Nurses' Health Study I and II (NHS, NHS II) and 4,537 women with a history of GDM from NHS II. Participants reported history of breastfeeding via follow-up questionnaires. Incident CVD by 2017 comprised stroke or coronary heart disease (CHD) (myocardial infarction, coronary revascularization). Adjusted hazard ratios (aHRs) and 95% CIs were estimated using Cox models.RESULTS: We documented 1,159 incident CVD cases among women with type 2 diabetes in both cohorts during 188,874 person-years of follow-up and 132 incident CVD cases among women with a GDM history during 100,218 person-years of follow-up. Longer lifetime duration of breastfeeding was significantly associated with lower CVD risk among women with type 2 diabetes, with pooled aHR of 0.68 (95% CI 0.54-0.85) for >18 months versus 0 months and 0.94 (0.91-0.98) per 6-month increment in breastfeeding. Similar associations were observed with CHD (pooled aHR 0.93 [0.88-0.97]) but not with stroke (0.96 [0.91-1.02]) per 6-month increment in breastfeeding. Among women with GDM history, >18 months versus 0 months of breastfeeding was associated with an aHR of 0.49 (0.28-0.86) for total CVD.CONCLUSIONS: Longer duration of breastfeeding was associated with lower risk of CVD in women with type 2 diabetes or GDM.",
author = "Anna Birukov and Marta Guasch-Ferr{\'e} and Ley, {Sylvia H} and Tobias, {Deirdre K} and Fenglei Wang and Clemens Wittenbecher and Jiaxi Yang and Manson, {JoAnn E} and Chavarro, {Jorge E} and Hu, {Frank B} and Cuilin Zhang",
note = "{\textcopyright} 2024 by the American Diabetes Association.",
year = "2024",
doi = "10.2337/dc23-1494",
language = "English",
volume = "47",
pages = "720--728",
journal = "Diabetes Care",
issn = "1935-5548",
publisher = "American Diabetes Association",
number = "4",

}

RIS

TY - JOUR

T1 - Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes

T2 - Findings From Two Large Prospective Cohorts

AU - Birukov, Anna

AU - Guasch-Ferré, Marta

AU - Ley, Sylvia H

AU - Tobias, Deirdre K

AU - Wang, Fenglei

AU - Wittenbecher, Clemens

AU - Yang, Jiaxi

AU - Manson, JoAnn E

AU - Chavarro, Jorge E

AU - Hu, Frank B

AU - Zhang, Cuilin

N1 - © 2024 by the American Diabetes Association.

PY - 2024

Y1 - 2024

N2 - OBJECTIVE: Breastfeeding duration is inversely associated with risks of cardiovascular disease (CVD) and type 2 diabetes in parous women. However, the association among women at high risk, including women with type 2 diabetes or gestational diabetes mellitus (GDM) is unclear.RESEARCH DESIGN AND METHODS: We included 15,146 parous women with type 2 diabetes from the Nurses' Health Study I and II (NHS, NHS II) and 4,537 women with a history of GDM from NHS II. Participants reported history of breastfeeding via follow-up questionnaires. Incident CVD by 2017 comprised stroke or coronary heart disease (CHD) (myocardial infarction, coronary revascularization). Adjusted hazard ratios (aHRs) and 95% CIs were estimated using Cox models.RESULTS: We documented 1,159 incident CVD cases among women with type 2 diabetes in both cohorts during 188,874 person-years of follow-up and 132 incident CVD cases among women with a GDM history during 100,218 person-years of follow-up. Longer lifetime duration of breastfeeding was significantly associated with lower CVD risk among women with type 2 diabetes, with pooled aHR of 0.68 (95% CI 0.54-0.85) for >18 months versus 0 months and 0.94 (0.91-0.98) per 6-month increment in breastfeeding. Similar associations were observed with CHD (pooled aHR 0.93 [0.88-0.97]) but not with stroke (0.96 [0.91-1.02]) per 6-month increment in breastfeeding. Among women with GDM history, >18 months versus 0 months of breastfeeding was associated with an aHR of 0.49 (0.28-0.86) for total CVD.CONCLUSIONS: Longer duration of breastfeeding was associated with lower risk of CVD in women with type 2 diabetes or GDM.

AB - OBJECTIVE: Breastfeeding duration is inversely associated with risks of cardiovascular disease (CVD) and type 2 diabetes in parous women. However, the association among women at high risk, including women with type 2 diabetes or gestational diabetes mellitus (GDM) is unclear.RESEARCH DESIGN AND METHODS: We included 15,146 parous women with type 2 diabetes from the Nurses' Health Study I and II (NHS, NHS II) and 4,537 women with a history of GDM from NHS II. Participants reported history of breastfeeding via follow-up questionnaires. Incident CVD by 2017 comprised stroke or coronary heart disease (CHD) (myocardial infarction, coronary revascularization). Adjusted hazard ratios (aHRs) and 95% CIs were estimated using Cox models.RESULTS: We documented 1,159 incident CVD cases among women with type 2 diabetes in both cohorts during 188,874 person-years of follow-up and 132 incident CVD cases among women with a GDM history during 100,218 person-years of follow-up. Longer lifetime duration of breastfeeding was significantly associated with lower CVD risk among women with type 2 diabetes, with pooled aHR of 0.68 (95% CI 0.54-0.85) for >18 months versus 0 months and 0.94 (0.91-0.98) per 6-month increment in breastfeeding. Similar associations were observed with CHD (pooled aHR 0.93 [0.88-0.97]) but not with stroke (0.96 [0.91-1.02]) per 6-month increment in breastfeeding. Among women with GDM history, >18 months versus 0 months of breastfeeding was associated with an aHR of 0.49 (0.28-0.86) for total CVD.CONCLUSIONS: Longer duration of breastfeeding was associated with lower risk of CVD in women with type 2 diabetes or GDM.

U2 - 10.2337/dc23-1494

DO - 10.2337/dc23-1494

M3 - Journal article

C2 - 38377484

VL - 47

SP - 720

EP - 728

JO - Diabetes Care

JF - Diabetes Care

SN - 1935-5548

IS - 4

ER -

ID: 386375990