Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362

Research output: Contribution to journal › Editorial › Research

Standard

Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362. / Plucińska, Kaja; Barger, Steven W.

In: Journal of Neurochemistry, Vol. 145, No. 5, 2018, p. 358-361.

Research output: Contribution to journal › Editorial › Research

Harvard

Plucińska, K & Barger, SW 2018, 'Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362', Journal of Neurochemistry, vol. 145, no. 5, pp. 358-361. https://doi.org/10.1111/jnc.14334

APA

Plucińska, K., & Barger, S. W. (2018). Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362. Journal of Neurochemistry, 145(5), 358-361. https://doi.org/10.1111/jnc.14334

Vancouver

Plucińska K, Barger SW. Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362. Journal of Neurochemistry. 2018;145(5):358-361. https://doi.org/10.1111/jnc.14334

Author

Plucińska, Kaja ; Barger, Steven W. / Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362. In: Journal of Neurochemistry. 2018 ; Vol. 145, No. 5. pp. 358-361.

Bibtex

@article{af7f161d111842c785a4c15e46a41572,
title = "Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner?: An Editorial for {"}Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain{"} on page 362",
abstract = "This editorial highlights an article by McKee and colleagues in the current issue of Journal of Neurochemistry, in which the authors report epigenetic changes linked to one-carbon metabolism in prefrontal cortex (PFC) of murine offspring from dams fed high-fat diet to mimic maternal obesity. The group found that high-fat diet feeding in utero increases weight gain in offspring and dynamically alters DNA methylation in the PFC of male but not female brains. These epigenetic marks were associated with a shift in brain one-carbon metabolism (folate and methionine) intermediates and were normalized by early-life methyl-donor supplementation in a sex-specific manner.",
author = "Kaja Pluci{\'n}ska and Barger, {Steven W}",
note = "{\textcopyright} 2018 International Society for Neurochemistry.",
year = "2018",
doi = "10.1111/jnc.14334",
language = "English",
volume = "145",
pages = "358--361",
journal = "Journal of Neurochemistry",
issn = "0022-3042",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner?

T2 - An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362

AU - Plucińska, Kaja

AU - Barger, Steven W

N1 - © 2018 International Society for Neurochemistry.

PY - 2018

Y1 - 2018

N2 - This editorial highlights an article by McKee and colleagues in the current issue of Journal of Neurochemistry, in which the authors report epigenetic changes linked to one-carbon metabolism in prefrontal cortex (PFC) of murine offspring from dams fed high-fat diet to mimic maternal obesity. The group found that high-fat diet feeding in utero increases weight gain in offspring and dynamically alters DNA methylation in the PFC of male but not female brains. These epigenetic marks were associated with a shift in brain one-carbon metabolism (folate and methionine) intermediates and were normalized by early-life methyl-donor supplementation in a sex-specific manner.

AB - This editorial highlights an article by McKee and colleagues in the current issue of Journal of Neurochemistry, in which the authors report epigenetic changes linked to one-carbon metabolism in prefrontal cortex (PFC) of murine offspring from dams fed high-fat diet to mimic maternal obesity. The group found that high-fat diet feeding in utero increases weight gain in offspring and dynamically alters DNA methylation in the PFC of male but not female brains. These epigenetic marks were associated with a shift in brain one-carbon metabolism (folate and methionine) intermediates and were normalized by early-life methyl-donor supplementation in a sex-specific manner.

U2 - 10.1111/jnc.14334

DO - 10.1111/jnc.14334

M3 - Editorial

C2 - 29663393

VL - 145

SP - 358

EP - 361

JO - Journal of Neurochemistry

JF - Journal of Neurochemistry

SN - 0022-3042

IS - 5

ER -

ID: 221832293