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  1. 2022
  2. Published

    Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention

    Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, Gieger, C., Graff, M., Hall, L. M., Haller, T., Hartwig, F. P., Hillis, D. A., Huikari, V., Heard-Costa, N., Holzapfel, C., Jackson, A. U., Johansson, A., Jorgensen, A. M., Kaakinen, M. A., Karlsson, R., Kerr, K. F., Kim, B., Koolhaas, C. M., Kutalik, Z., Pacolet, A., Zhao, J., Balslev-Harder, M. N., Grarup, Niels, Linneberg, Allan René, Hansen, Torben, Melbye, M., Pedersen, Oluf Borbye, Pers, Tune H, Sørensen, Thorkild I.A., Zierath, Juleen R, Kilpeläinen, Tuomas O., Loos, Ruth & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

    Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, Henrik, Pers, Tune H, Mortensen, P. B., Mors, O., Nordentoft, Merete, Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, Anders Peter, Melbye, M., Ullum, H., Berkovic, S. F., Werge, Thomas & Feenstra, B., 2022, In: Brain. 145, 2, p. 555–568

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Hindbrain circuits in the control of eating behaviour and energy balance

    Cheng, W., Gordian, D., Ludwig, M. Q., Pers, Tune H, Seeley, R. J. & Myers, M. G., 2022, In: Nature Metabolism. 4, 7, p. 826-835 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Microbiome and metabolome features of the cardiometabolic disease spectrum

    Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. & 44 others, Coelho, L. P., Falony, G., Fellahi, S., Galan, P., Galleron, N., Helft, G., Hoyles, L., Isnard, R., Le Chatelier, E., Julienne, H., Olsson, L., Pedersen, H. K., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J. E., Schmidt, T. S. B., Vieira-Silva, S., Li, P., Zimmermann-Kogadeeva, M., Lewinter, C., Søndertoft, N. B., Hansen, T. H., Gauguier, D., Gøtze, J. P., Køber, Lars Valeur, Kornowski, R., drb459, drb459, Hansen, Torben, Zucker, J. D., Hercberg, S., Letunic, I., Bäckhed, F., Oppert, J. M., Nielsen, J., Raes, J., Bork, P., Stumvoll, M., Segal, E., Clément, K., Dumas, M. E., Ehrlich, S. D. & Pedersen, Oluf Borbye, 2022, In: Nature Medicine. 28, 2, p. 303-314

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Multiomics signatures of type 1 diabetes with and without albuminuria

    Clos-Garcia, M., Ahluwalia, Tarun Veer Singh, Winther, S. A., Henriksen, P., Ali, M., Fan, Yong, Stankevic, Evelina, Lyu, Liwei, Vogt, J. K., Hansen, Torben, Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2022, In: Frontiers in Endocrinology. 13, 17 p., 1015557.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, Freese, J., Herd, P., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., McCreight, J. C., McIntyre, M. H., Mountain, J. L., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Pers, Tune H, Timshel, P., Ahluwalia, Tarun Veer Singh, Bønnelykke, Klaus, Bisgaard, H., Sørensen, Thorkild I.A., 23andMe Research Team, 2. R. T., Social Science Genetic Association Consortium, S. S. G. A. C. & LifeLines Cohort Study, L. C. S., 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

    Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, Hall, Vanessa Jane, 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

    Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Hansen, M., Hansen, T., Li, T., Olsen, L., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Hansen, Thomas Folkmann, Nordentoft, Merete, Werge, Thomas, Plath, N., Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, S. D. C. A. G. O. T. P. G. C. & iPSYCH, I., 2022, In: Biological Psychiatry. 91, 1, p. 107-117

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis

    Fred, Rikard Göran, Steen Pedersen, J., Thompson, J. J., Lee, J., Timshel, P. N., Stender, S., Rygg, M. O., Gluud, Lise Lotte, Bjerregaard Kristiansen, V., Bendtsen, Flemming, Hansen, Torben & Pers, Tune H, 2022, In: Scientific Reports. 12, 1, 13 p., 13484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Sustained inhibition of NPY/AgRP neuronal activity by FGF1

    Hwang, E., Scarlett, J. M., Baquero, A. F., Bennett, C. M., Dong, Y., Chau, D., Brown, Jenny, Mercer, A. J., Meek, T. H., Grove, K. L., Phan, B. A. N., Morton, G. J., Williams, K. W. & Schwartz, M. W., 2022, In: JCI insight. 7, 17, 11 p., e160891.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    microRNA-based signatures obtained from endometrial fluid identify implantative endometrium

    Ibañez-Perez, J., Díaz-Nuñez, M., Clos-García, M., Lainz, L., Iglesias, M., Díez-Zapirain, M., Rabanal, A., Bárcena, L., González, M., Lozano, J. J., Marigorta, U. M., González, E., Royo, F., Aransay, A. M., Subiran, N., Matorras, R. & Falcón-Pérez, J. M., 2022, In: Human Reproduction. 37, 10, p. 2375-2391 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2021
  14. Published

    A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

    Ni, G., Zeng, J., Revez, J. A., Wang, Y., Zheng, Z., Ge, T., Restuadi, R., Kiewa, J., Nyholt, D. R., Coleman, J. R. I., Smoller, J. W., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A. & 21 others, Huang, H., Pers, Tune H, Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Hansen, M., Hansen, Thomas Folkmann, Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2021, In: Biological Psychiatry. 90, 9, p. 611-620

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A genetic map of the mouse dorsal vagal complex and its role in obesity

    Ludwig, M. Q., Cheng, W., Gordian, D., Lee, J., Paulsen, S. J., Hansen, S. N., Egerod, Kristoffer Lihme, Barkholt, P., Rhodes, C. J., Secher, A., Knudsen, L. B., Pyke, C., Myers, M. G. & Pers, Tune H, 2021, In: Nature Metabolism. 3, p. 530-545

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Association and genetic overlap between clinical chemistry tests and migraine

    Tanha, H. M. & The International Headache Genetics Consortium (IHGC), T. I. H. G. C. (., 2021, In: Cephalalgia. 41, 11-12, p. 1208-1221 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, Treutlein, J., Witt, S. H., Cichon, S., Kogevinas, M., Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pers, Tune H, Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Nordentoft, Merete, Werge, Thomas, Hansen, Thomas Folkmann, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

    Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M., Kjolby, M., Membrez, M., Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W., Sanders, M. J. & 4 others, Descombes, P., Chen, S., Steinberg, G. R. & Sakamoto, Kei, 2021, In: Molecular Metabolism. 51, 18 p., 101228.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Genetic insights into biological mechanisms governing human ovarian ageing

    Ruth, K. S., Day, F. R., Hussain, J., Martinez-Marchal, A., Aiken, C. E., Azad, A., Thompson, D. J., Knoblochova, L., Abe, H., Tarry-Adkins, J. L., Gonzalez, J. M., Fontanillas, P., Claringbould, A., Bakker, O. B., Sulem, P., Walters, R. G., Terao, C., Turon, S., Horikoshi, M., Lin, K. & 36 others, Onland-Moret, N. C., Sankar, A., Hertz, Emil Peter Thrane, Timshel, P. N., Shukla, V., Borup, R., Olsen, K. W., Aguilera, P., Ferrer-Roda, M., Huang, Y., Stankovic, S., Timmers, P. R. H. J., Ahearn, T. U., Alizadeh, B. Z., Naderi, E., Andrulis, I. L., Arnold, A. M., Aronson, K. J., Augustinsson, A., Bojesen, Stig Egil, Hoffding, M. K., Shrikhande, A., Pers, Tune H, Grøndahl, M. L., tcg964, tcg964, Lopez-Contreras, Andres, Daniel, J. A., Hoffmann, Eva, Biobank-based Integrative Omics St, B. I. O. S., eQTLGen Consortium, E. C., BioBank Japan Project, B. J. P., China Kadoorie Biobank Collaborati, C. K. B. C., kConFab Investigators, K. I., LifeLines Cohort Study, L. C. S., InterAct Consortium, I. C. & 23 Me Res Team, 2. M. R. T., 2021, In: Nature. 596, p. 393-397

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells

    Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    How robust are cross-population signatures of polygenic adaptation in humans?

    Refoyo Martínez, Alba, Liu, S., Jørgensen, A. M., Jin, X., Albrechtsen, Anders, Martin, A. R. & Racimo, Fernando, 2021, In: Peer Community Journal. 1, 54 p., e22.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

    Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, Puri, P. L. & Jessen, N., 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

    Johnsen, Cecilie Hundahl, Kotzbeck, P., Burm, Hayley Beth, Christiansen, S. H., Pedersen, Lola Julie Torz, zmw799, zmw799, Madsen, M. P., Ratner, C., Serup, A. K., Thompson, J. J., Eichmann, T. O., Pers, Tune H, Woldbye, David Paul Drucker, Piomelli, D., Kiens, Bente, Zechner, R., Skov, Louise Julie & Holst, Birgitte, 2021, In: Molecular Metabolism. 47, 16 p., 101174.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

    Mills, M. C., Tropf, F. C., Brazel, D. M., van Zuydam, N., Vaez, A., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A. K., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Jan Bonder, M., Boomsma, D. I., Christiansen, M. W., Claringbould, A., Deelen, P., Esko, T., Favé, M-J. & 33 others, Franke, L., Frayling, T., Gharib, S. A., Gibson, G., Heijmans, B. T., Hemani, G., Jansen, R., Kähönen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Krohn, K., Kronberg, J., Kukushkina, V., Kutalik, Z., Lee, B., Lehtimäki, T., Loeffler, M., Marigorta, U. M., Mei, H., Milani, L., Montgomery, G. W., Müller-Nurasyid, M., Nauck, M., Nivard, M. G., Penninx, B. W. J. H., Møllegaard, Stine, Pers, Tune H, eQTLGen Consortium, E. C., BIOS Consortium, B. C. & Human Reproductive Behaviour Consortium, H. R. B. C., 2021, In: Nature Human Behaviour. 5, p. 1717-1730

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

    Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies

    Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

    Brown, Jenny, Bentsen, M. A., Belmont-Rausch, Dylan Matthew, Phan, B. A., Wieck, D., Wasanwala, H., Matsen, M. E., Acharya, N., Richardson, N. E., Zhao, X., Zhai, P., Secher, A., Morton, G. J., Pers, Tune H, Schwartz, M. W. & Scarlett, J. M., 2021, In: iScience. 24, 9, 19 p., 102944.

    Research output: Contribution to journal › Journal article › Research › peer-review

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