- 2019
- Published
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L., Caplin, A. H., Chen, C., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Zhang, F., Auton, A., Boardman, J. D., Clark, D. W., Conlin, A., Dolan, C. C., Fischbacher, U., Groenen, P. J. F., Harris, K. M., Hasler, G., Hofman, A., Ikram, M. A., Jain, S., Karlsson, R., Pers, Tune H & 23and Me Research Team, 2. M. R. T., 2019, In: Nature Genetics. 51, 2, p. 245-257Research output: Contribution to journal › Journal article › peer-review
- Published
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., Vlachos, I. S., McCabe, C., Pers, Tune H, Brandes, A., White, C., Keenan, B., Cimpean, M., Winn, P., Panteliadis, I. P., Robbins, A., Andlauer, T. F. M., Zarzycki, O., Dubois, B., Goris, A., Søndergaard, H. B., Sellebjerg, Finn Thorup, Sørensen, Per Soelberg, Ullum, H., Thørner, L. W., Saarela, J., Cournu-Rebeix, I., Damotte, V., Fontaine, B., Guillot-Noel, L., Lathrop, M., Vukusic, S., Berthele, A., Pongratz, V., Buck, D., Gasperi, C., Graetz, C., Grummel, V., Hemmer, B., Hoshi, M., Knier, B., Korn, T., Lill, C. M., Luessi, F., Karpe, F., Lage, K., Oturai, A., International Multiple Sclerosis Genetics Consortium, I. M. S. G. C. & ANZgene, IIBDGC, WTCCC2, A. I. W., 2019, In: Science. 365, 6460, eaav7188.Research output: Contribution to journal › Journal article › peer-review
- Published
PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data
Hsu, Y. H., Churchhouse, C., Pers, Tune H, Mercader, J. M., Metspalu, A., Fischer, K., Fortney, K., Morgen, E. K., Gonzalez, C., Gonzalez, M. E., Esko, T. & Hirschhorn, J. N., 2019, In: PLOS Computational Biology. 15, 1, 26 p., e1006734.Research output: Contribution to journal › Journal article › peer-review
- Published
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Hopkins, L., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Pers, Tune H, Hansen, M., Hansen, Thomas Folkmann, Li, T., Olsen, L., Pantelis, C., Rasmussen, Henrik Berg, Werge, Thomas, Wellcome Trust Case Control Consortium 2, W. T. C. C. C. 2. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Production of stellate cells from induced pluripotent stem cells to study Alzheimer's disease pathology
Mogus, L., Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
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Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A., Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Jørgensen, T., Justesen, Johanne Marie, Karpe, F., Kovacs, P., Li, J., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Pers, Tune H, drb459, drb459, Zhao, J. H., Loos, R. J. F. & CHD Exome+ Consortium, C. E. C., 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › peer-review
- Published
Revisiting How the Brain Senses Glucose-And Why
Bentsen, M. A., Mirzadeh, Z. & Schwartz, M. W., 2019, In: Cell Metabolism. 29, 1, p. 11-17Research output: Contribution to journal › Review › peer-review
- Published
RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones
Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.Research output: Contribution to journal › Conference article › peer-review
- Published
Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L., Mori, Yuki, Asenjo Martinez, A., Lisa Vargas, Irene, Seemann, Ernst Stefan, Lee, J. T. H., Patikis, N., Peralvo Vidal, Juan Miguel, Pihl, M., Kornum, Birgitte Rahbek, Thomsen, Preben Dybdahl, Hyttel, P., Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 45 p.Research output: Contribution to conference › Paper › Communication
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › peer-review
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
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Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Research output: Contribution to journal › Journal article › peer-review
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Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus
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The gut microbiota in multiple sclerosis varies with disease activity
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Microbiome and metabolome features of the cardiometabolic disease spectrum
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