Sakamoto Group

  1. Published

    mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b

    Uehara, K., Lee, W. D., Stefkovich, M., Biswas, Dipsikha, Santoleri, D., Whitlock, A. G., Quinn, W., Coopersmith, T., Creasy, K. T., Rader, D. J., Sakamoto, Kei, Rabinowitz, J. D. & Titchenell, P. M., 2024, In: Journal of Clinical Investigation. 134, 7, 13 p., e173782.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

    Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zeqiraj, E., Turk, B. E. & Sakamoto, Kei, 1 Nov 2012, In: Cellular Signalling. 24, 11, p. 2085-2094 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site

    Sanders, M. J., Ratinaud, Y., Neopane, K., Bonhoure, N., Day, E. A., Ciclet, O., Lassueur, S., Pinta, M. N., Deak, M., Brinon, B., Christen, S., Steinberg, G. R., Barron, D. & Sakamoto, Kei, 2022, In: Journal of Biological Chemistry. 298, 5, 15 p., 101852.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    PEN2: Metformin’s new partner at lysosome

    Sakamoto, Kei & Jessen, N., 2022, In: Cell Research. 32, p. 507-508

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy

    Roberts, F. L. & Markby, G. R., 2021, In: Cells. 10, 10, 29 p., 2639.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

    Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M., Kjolby, M., Membrez, M., Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W., Sanders, M. J. & 4 others, Descombes, P., Chen, S., Steinberg, G. R. & Sakamoto, Kei, 2021, In: Molecular Metabolism. 51, 18 p., 101228.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

    Nguyen-Tu, M., Harris, J., Martinez-Sanchez, A., Chabosseau, P., Hu, M., Georgiadou, E., Pollard, A., Otero, P., Lopez-Noriega, L., Leclerc, I., Sakamoto, Kei, Schmoll, D., Smith, D. M., Carling, D. & Rutter, G. A., 2022, In: Diabetologia. 65, p. 997-1011 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

    Neopane, K., Kozlov, N., Negoita, F., Murray-Segal, L., Brink, R., Hoque, A., Ovens, A. J., Tjin, G., McAloon, L. M., Yu, D., Ling, N. X. Y., Sanders, M. J., Oakhill, J. S., Scott, J. W., Steinberg, G. R., Loh, K., Kemp, B. E., Sakamoto, Kei & Galic, S., 2022, In: Cell Reports. 41, 12, 26 p., 111862.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

    Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, Sakamoto, Kei, 2023, In: Molecular Metabolism. 75, 14 p., 101761.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Mechanism of glycogen synthase inactivation and interaction with glycogenin

    Marr, L., Biswas, Dipsikha, Daly, L. A., Browning, C., Vial, S. C. M., Maskell, D. P., Hudson, C., Bertrand, J. A., Pollard, J., Ranson, N. A., Khatter, H., Eyers, C. E., Sakamoto, Kei & Zeqiraj, E., 2022, In: Nature Communications. 13, 1, 14 p., 3372.

    Research output: Contribution to journalJournal articleResearchpeer-review

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