New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy

Research output: Contribution to journal › Review › Research › peer-review

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New Insights into Molecular Mechanisms Mediating Adaptation to Exercise : A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy. / Roberts, Fiona Louise; Markby, Greg Robert.

In: Cells, Vol. 10, No. 10, 2639, 2021.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Roberts, FL & Markby, GR 2021, 'New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy', Cells, vol. 10, no. 10, 2639. https://doi.org/10.3390/cells10102639

APA

Roberts, F. L., & Markby, G. R. (2021). New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy. Cells, 10(10), [2639]. https://doi.org/10.3390/cells10102639

Vancouver

Roberts FL, Markby GR. New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy. Cells. 2021;10(10). 2639. https://doi.org/10.3390/cells10102639

Author

Roberts, Fiona Louise ; Markby, Greg Robert. / New Insights into Molecular Mechanisms Mediating Adaptation to Exercise : A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy. In: Cells. 2021 ; Vol. 10, No. 10.

Bibtex

@article{e52327143f0f4613b89ac009222cead1,
title = "New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy",
abstract = "Exercise itself is fundamental for good health, and when practiced regularly confers a myriad of metabolic benefits in a range of tissues. These benefits are mediated by a range of adaptive responses in a coordinated, multi-organ manner. The continued understanding of the molecular mechanisms of action which confer beneficial effects of exercise on the body will identify more specific pathways which can be manipulated by therapeutic intervention in order to prevent or treat various metabolism-associated diseases. This is particularly important as exercise is not an available option to all and so novel methods must be identified to confer the beneficial effects of exercise in a therapeutic manner. This review will focus on key emerging molecular mechanisms of mitochon-drial biogenesis, autophagy and mitophagy in selected, highly metabolic tissues, describing their regulation and contribution to beneficial adaptations to exercise.",
keywords = "Autophagy, Exercise, Mitophagy and mitochondrial biogenesis, Molecular signaling",
author = "Roberts, {Fiona Louise} and Markby, {Greg Robert}",
note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2021",
doi = "10.3390/cells10102639",
language = "English",
volume = "10",
journal = "Cells",
issn = "2073-4409",
publisher = "MDPI AG",
number = "10",

}

RIS

TY - JOUR

T1 - New Insights into Molecular Mechanisms Mediating Adaptation to Exercise

T2 - A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy

AU - Roberts, Fiona Louise

AU - Markby, Greg Robert

N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2021

Y1 - 2021

N2 - Exercise itself is fundamental for good health, and when practiced regularly confers a myriad of metabolic benefits in a range of tissues. These benefits are mediated by a range of adaptive responses in a coordinated, multi-organ manner. The continued understanding of the molecular mechanisms of action which confer beneficial effects of exercise on the body will identify more specific pathways which can be manipulated by therapeutic intervention in order to prevent or treat various metabolism-associated diseases. This is particularly important as exercise is not an available option to all and so novel methods must be identified to confer the beneficial effects of exercise in a therapeutic manner. This review will focus on key emerging molecular mechanisms of mitochon-drial biogenesis, autophagy and mitophagy in selected, highly metabolic tissues, describing their regulation and contribution to beneficial adaptations to exercise.

AB - Exercise itself is fundamental for good health, and when practiced regularly confers a myriad of metabolic benefits in a range of tissues. These benefits are mediated by a range of adaptive responses in a coordinated, multi-organ manner. The continued understanding of the molecular mechanisms of action which confer beneficial effects of exercise on the body will identify more specific pathways which can be manipulated by therapeutic intervention in order to prevent or treat various metabolism-associated diseases. This is particularly important as exercise is not an available option to all and so novel methods must be identified to confer the beneficial effects of exercise in a therapeutic manner. This review will focus on key emerging molecular mechanisms of mitochon-drial biogenesis, autophagy and mitophagy in selected, highly metabolic tissues, describing their regulation and contribution to beneficial adaptations to exercise.

KW - Autophagy

KW - Exercise

KW - Mitophagy and mitochondrial biogenesis

KW - Molecular signaling

U2 - 10.3390/cells10102639

DO - 10.3390/cells10102639

M3 - Review

C2 - 34685618

AN - SCOPUS:85116109748

VL - 10

JO - Cells

JF - Cells

SN - 2073-4409

IS - 10

M1 - 2639

ER -

ID: 283751432