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Challenges in tackling energy expenditure as obesity therapy: From preclinical models to clinical application
Löffler, M. C., Betz, M. J., Blondin, D. P., Augustin, R., Sharma, A. K., Tseng, Y. H., Schéele, Camilla Charlotte Nielsen, Zimdahl, H., Mark, M., Hennige, A. M., Wolfrum, C., Langhans, W., Hamilton, B. S. & Neubauer, H., 2021, In: Molecular Metabolism. 51, 15 p., 101237.Research output: Contribution to journal › Review › Research › peer-review
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Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity
Mathur, N., Severinsen, M. C. K., Jensen, M. E., Naver, L., Schrölkamp, Maren, Laye, M. J., Watt, M. J., Nielsen, S., Krogh-Madsen, Rikke, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2022, In: Frontiers in Cell and Developmental Biology. 10, 12 p., 983899.Research output: Contribution to journal › Journal article › Research › peer-review
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Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells
Min, S. Y., Desai, A., Yang, Z., Sharma, A., DeSouza, T., Genga, R. M. J., Kucukural, A., Lifshitz, L. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen, Maehr, R., Garber, M. & Corvera, S., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 36, p. 17970-17979Research output: Contribution to journal › Journal article › Research › peer-review
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Transient postprandial increase in intact circulating fibroblast growth factor-21 levels after Roux-en-Y gastric bypass: A randomized controlled clinical trial
Nielsen, M. S., Søberg, S., Schmidt, J. B., Chenchar, A., Sjödin, Anders Mikael & Gillum, M. P., 2021, In: PeerJ. 9, 14 p., e11174.Research output: Contribution to journal › Journal article › Research › peer-review
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De-novo reconstruction and identification of transcriptional gene regulatory network modules differentiating single-cell clusters
Oubounyt, M., Elkjaer, M. L., Laske, T., Grønning, Alexander GB, Moeller, M. J. & Baumbach, J., 2023, In: NAR Genomics and Bioinformatics. 5, 1, 17 p., lqad018.Research output: Contribution to journal › Journal article › Research › peer-review
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Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots
Palani, Nagendra Prasad, Horvath, C., Timshel, P. N., Folkertsma, P., Grønning, Alexander GB, Henriksen, T. I., Peijs, Lone, Jensen, V. H., Sun, W., Jespersen, N. Z., Wolfrum, C., Pers, Tune H, Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2023, In: Nature Metabolism. 5, 6, p. 996-1013 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat
Plucinska, Kaja, Jespersen, N. Z., Brown, E. L., Petersen, P. S., Rupar, K., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Emanuelli, Brice, 2020, In: Frontiers in Endocrinology. 11, 7 p., 579785.Research output: Contribution to journal › Journal article › Research › peer-review
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Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis
Rauch, A., Haakonsson, A. K., Madsen, J. G. S., Larsen, M., Forss, I., Madsen, M. R., Van Hauwaert, E. L., Wiwie, C., Jespersen, N. Z., Tencerova, M., Nielsen, R., Larsen, B. D., Roettger, R., Baumbach, J., Schéele, Camilla Charlotte Nielsen, Kassem, M. & Mandrup, S., 2019, In: Nature Genetics. 51, 4, p. 716-727Research output: Contribution to journal › Journal article › Research › peer-review
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Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
Sanchez-Gurmaches, J., Tang, Y., Jespersen, N. Z., Wallace, M., Martinez Calejman, C., Gujja, S., Li, H., Edwards, Y. J. K., Wolfrum, C., Metallo, C. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Guertin, D. A., 9 Jan 2018, In: Cell Metabolism. 27, 1, p. 195-209.e6Research output: Contribution to journal › Journal article › Research › peer-review
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Perspectives on the role of brown adipose tissue in human body temperature and metabolism
Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 3 p., 100427.Research output: Contribution to journal › Editorial › Research
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Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism
Schéele, Camilla Charlotte Nielsen & Wolfrum, C., 2020, In: Endocrine Reviews. 41, 1, p. 53-65Research output: Contribution to journal › Review › Research › peer-review
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Functional diversity of human adipose tissue revealed by spatial mapping
Schéele, Camilla Charlotte Nielsen & Wolfrum, C., 2021, In: Nature Reviews Endocrinology. 17, p. 713-714 2 p.Research output: Contribution to journal › Editorial › Research
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Can we target obesity using a single-cell atlas of adipose tissue?
Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2022, In: Med. 3, 5, p. 276-278 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Isolation and Characterization of Human Brown Adipocytes
Schéele, Camilla Charlotte Nielsen, Henriksen, T. I. & Nielsen, S., 2022, In: Methods in Molecular Biology. 2448, p. 217-234 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution
Schlein, C., Fischer, A. W., Sass, F., Worthmann, A., Tödter, K., Jaeckstein, M. Y., Behrens, J., Lynes, M. D., Kiebish, M. A., Narain, N. R., Bussberg, V., Darkwah, A., Jespersen, N. Z., Nielsen, S., Scheele, C., Schweizer, M., Braren, I., Bartelt, A., Tseng, Y. H., Heeren, J. & 1 others, , 2021, In: Cell Reports. 34, 2, 19 p., 108624.Research output: Contribution to journal › Journal article › Research › peer-review
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Muscle-Organ Crosstalk: The Emerging Roles of Myokines
Severinsen, M. C. K. & Pedersen, Bente Klarlund, 2020, In: Endocrine Reviews. 41, 4, p. 594-609Research output: Contribution to journal › Review › Research › peer-review
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Exercise and browning of white adipose tissue - a translational perspective
Severinsen, M. C. K., Schéele, Camilla Charlotte Nielsen & Pedersen, Bente Klarlund, 2020, In: Current Opinion in Pharmacology. 52, p. 18-24 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men
Soberg, S., Löfgren, J., Philipsen, F. E., Jensen, M., Hansen, Adam Espe, Ahrens, E., Nystrup, K. B., Nielsen, R. D., Solling, C., Wedell-Neergaard, A., Berntsen, M., Loft, A., Kjær, Andreas, Gerhart-Hines, Zach, Johannesen, H. H., Pedersen, Bente Klarlund, Karstoft, Kristian & Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Himalayan bacterial endophytes enhance microalgal cell numbers and chlorophyll content in synthetic co-culture
Sonowal, S., Palani, Nagendra Prasad, Ahmed, R., Debbarma, J., Chikkaputtaiah, C., Basar, E. & Velmurugan, N., 2022, In: Journal of Applied Phycology. 34, 5, p. 2383-2400Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, , 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, , 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans
Søberg, S., Sandholt, C. H., Z. Jespersen, N., Toft, U., L. Madsen, A., Holstein-Rønsbo, Stephanie, Grevengoed, Trisha Jean, Christensen, Karl Bang, Bredie, Wender, Potthoff, M. J., P. J. Solomon, T., Schéele, Camilla Charlotte Nielsen, Linneberg, Allan René, Jørgensen, T., Pedersen, Oluf Borbye, Hansen, Torben, Gillum, M. P. & Grarup, Niels, 2017, In: Cell Metabolism. 25, 5, p. 1045-1053 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise
Ziegler, A. K., Damgaard, A., Mackey, Abigail, Schjerling, Peter, Magnusson, Stig Peter, Olesen, A. T., Kjær, Michael & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p., 12069.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice
de Jong, J. M. A., Sun, W., Pires, N. D., Frontini, A., Balaz, M., Jespersen, N. Z., Feizi, A., Petrovic, K., Fischer, A. W., Bokhari, M. H., Niemi, T., Nuutila, P., Cinti, S., Nielsen, S., Schéele, Camilla Charlotte Nielsen, Virtanen, K., Cannon, B., Nedergaard, J., Wolfrum, C. & Petrovic, N., 2019, In: Nature Metabolism. 1, p. 830-843Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
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Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells
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Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men
Research output: Contribution to journal › Journal article › Research › peer-review
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