- 2024
- Published
An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
Apuschkin, Mia, Burm, Hayley Beth, Schmidt, Jan Hendrik, Skov, Louise Julie, Andersen, Rita Chan, Bowin, Carl-Fredrik, Støier, J. F., Jensen, Kathrine Louise, Posselt, Leonie Pauline, Dmytriyeva, O., Sørensen, Andreas Toft, Egerod, Kristoffer Lihme, Holst, B., Rickhag, M., Schwartz, Thue W. & Gether, Ulrik, 2024, In: Cell Reports. 43, 7, 23 p., 114509.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
Dollet, L., Lundell, L. S., Chibalin, A. V., Pendergrast, L. A., Pillon, N. J., Lansbury, Elizabeth Laura, Elmastas, M., Frendo-Cumbo, S., Jalkanen, J., de Castro Barbosa, T., Cervone, D. T., Caidahl, K., Dmytriyeva, O., Deshmukh, Atul Shahaji, Barrès, Romain, Rydén, M., Wallberg-Henriksson, H., Zierath, Juleen R & Krook, A., 2024, In: Cell Reports Medicine. 5, 1, 20 p., 101348.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1-directed NMDA receptor antagonism for obesity treatment
Petersen, J., Ludwig, M. Q., Juozaityte, V., Ranea-Robles, P., Svendsen, C., Hwang, E., Kristensen, A. W., Fadahunsi, N., Lund, J., Breum, A. W., Mathiesen, C. V., Sachs, L., Moreno-Justicia, R., Rohlfs, R., Ford, J. C., Douros, J. D., Finan, B., Portillo, B., Grose, K., Petersen, J. E. & 13 others, , 2024, In: Nature. 629, 8014, p. 1133–1141Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91
Iliyaz, Aslihan Shenol, Lückmann, Michael, Trauelsen, Mette, Lambrughi, M., Tiberti, M., Papaleo, E., Frimurer, Thomas Michael & Schwartz, Thue W., 2024, In: Molecular Cell. 84, 5, p. 955-966.e4 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple recent HCAR2 structures demonstrate a highly dynamic ligand binding and G protein activation mode
Iliyaz, Aslihan Shenol, Tenente, Ricardo Ramos Silva Costa, Lückmann, Michael, Frimurer, Thomas Michael & Schwartz, Thue W., 2024, In: Nature Communications. 15, 10 p., 5364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Lund, Camilla, Ranea-Robles, P., Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice
Makki, K., Brolin, H., Petersen, N., Henricsson, M., Christensen, D. P., Khan, M. T., Wahlström, A., Bergh, P., Tremaroli, V., Schoonjans, K., Marschall, H. & Bäckhed, F., 2023, In: Gut. 72, p. 314-324 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle
Abdelmoez, A. M., Dmytriyeva, O., Zurke, Y. X., Trauelsen, Mette, Marica, A. A., Savikj, M., Smith, J. A. B., Monaco, C., Schwartz, Thue W., Krook, A. & Pillon, N. J., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 324, 4, p. E289-E298 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors
Madsen, J. J., Petersen, Jacob Emil, Christensen, D. P., Hansen, J. B., Schwartz, Thue W., Frimurer, Thomas Michael & Olsen, O. H., 2023, In: Journal of Biological Chemistry. 299, 12, 11 p., 105438.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2
Petersen, Jacob Emil, Pedersen, M. H., Dmytriyeva, O., Nellemose, E., Arora, Tulika, Engelstoft, M. S., Asher, W. B., Javitch, J. A., Schwartz, Thue W. & Trauelsen, Mette, 2023, In: Molecular Metabolism. 74, 10 p., 101757.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 (GLP-1)
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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Aberrant intestinal microbiota in individuals with prediabetes
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Latest publications
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Research output: Contribution to journal › Journal article › Research › peer-review
Multiple recent HCAR2 structures demonstrate a highly dynamic ligand binding and G protein activation mode
Research output: Contribution to journal › Journal article › Research › peer-review
GLP-1-directed NMDA receptor antagonism for obesity treatment
Research output: Contribution to journal › Journal article › Research › peer-review