Zierath Group

  1. Published

    Zeitgebers of skeletal muscle and implications for metabolic health

    Gabriel, B. M. & Zierath, Juleen R, 2022, In: Journal of Physiology. 600, 5, p. 1027-1036

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

    Rabiee, A., Plucinska, Kaja, Isidor, Marie Sophie, Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda Oyarzabal, Marina, Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, Ali, Barrès, Romain, Jensen, O. N., Gerhart-Hines, Zach & Emanuelli, Brice, 2021, In: Molecular Metabolism. 44, 17 p., 101137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action

    Kellezi, Emilie Dalbram, Basse, A. L., Zierath, Juleen R & Treebak, Jonas Thue, 2019, In: Journal of Applied Physiology. 126, 4, p. 993-1005 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

    Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., Garratt, E. S., Vasiloglou, M. F., Chanvillard, L., Dalbram, E., Ehrlich, A. M., Sanchez-Garcia, J. L., Canto, C., Karagounis, L. G., Treebak, J. T., Migaud, M. E. & 15 others, Heshmat, R., Razi, F., Karnani, N., Ostovar, A., Farzadfar, F., Tay, S. K. H., Sanders, M. J., Lillycrop, K. A., Godfrey, K. M., Nakagawa, T., Moco, S., Koopman, R., Lynch, G. S., Sorrentino, V. & Feige, J. N., 2024, In: Nature Metabolism. 6, 3, p. 433–447

    Research output: Contribution to journalLetterResearchpeer-review

  5. Published

    Transient changes to metabolic homeostasis initiate mitochondrial adaptation to endurance exercise

    Dent, J. R., Stocks, Ben Nicholas, Campelj, D. G. & Philp, A., 2023, In: Seminars in Cell and Developmental Biology. 143, p. 3-16

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome

    McIlvenna, L. C., Altıntaş, Ali, Patten, R. K., McAinch, A. J., Rodgers, R. J., Stepto, N. K., Barrès, Romain & Moreno-Asso, A., 2022, In: The Journal of Physiology. 600, 14, p. 3313-3330

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

    Pillon, N. J., Gabriel, B. M., Dollet, L., Smith, J. A. B., Puig, L. S., Botella, J., Bishop, D. J., Krook, A. & Zierath, Juleen R, 2020, In: Nature Communications. 11, 1, 15 p., 470.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development

    Altıntaş, Ali, Laker, R. C., Garde, C., Barrès, Romain & Zierath, Juleen R, 2020, In: Epigenomics. 12, 8, p. 701-713

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Train like an athlete: applying exercise interventions to manage type 2 diabetes

    Savikj, M. & Zierath, Juleen R, 2020, In: Diabetologia. 63, 8, p. 1491-1499

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]

    Lundell, L. S., Parr, E. B., Devlin, B. L., Ingerslev, L. R., Altıntaş, Ali, Sato, S., Sassone-Corsi, P., Barrès, Romain, Zierath, Juleen R & Hawley, J. A., 2020, In: Nature Communications. 11, 1, 11 p., 4643.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis

    Sato, S., Basse, A. L., Schönke, M., Chen, S., Samad, M., Altıntaş, Ali, Laker, R. C., Kellezi, Emilie Dalbram, Barrès, Romain, Baldi, P., Treebak, Jonas Thue, Zierath, Juleen R & Sassone-Corsi, P., 2019, In: Cell Metabolism. 30, 1, p. 92-110.e4 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The use of a systems approach to increase NAD+ in human participants

    Henderson, John David, Quigley, S. N. Z., Chachra, S. S., Conlon, N. & Ford, D., 2024, In: npj Aging. 10, 12 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The role of the molecular circadian clock in human energy homeostasis

    Dollet, L., Pendergrast, L. A. & Zierath, Juleen R, 2021, In: Current Opinion in Lipidology. 32, 1, p. 16-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle

    Maasar, M. F., Turner, D. C., Gorski, P. P., Seaborne, R. A., Strauss, J. A., Shepherd, S. O., Cocks, M., Pillon, N. J., Zierath, Juleen R, Hulton, A. T., Drust, B. & Sharples, A. P., 2021, In: Frontiers in Physiology. 12, 17 p., 619447.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published
  17. Published

    Squeezing Flux Out of Fat

    Gonzalez-Franquesa, A. & Patti, M., 2018, In: Trends in Endocrinology and Metabolism. 29, 4, p. 201-202

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

    Williams, K., Ingerslev, L. R., Bork-Jensen, J., Wohlwend, M., Hansen, Ann Normann, Small, Lewin Barkla, Ribel-Madsen, R., Astrup, A., Pedersen, Oluf Borbye, Auwerx, J., Workman, C. T., Grarup, Niels, Hansen, Torben & Barrès, Romain, 2020, In: Nature Communications. 11, 16 p., 2695.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Seasonal light hours modulate peripheral clocks and energy metabolism in mice

    Small, Lewin Barkla, Lundell, L. S., Iversen, Jo Frøkjær, Ehrlich, Amy M, Dall, M., Basse, A. L., Kellezi, Emilie Dalbram, Hansen, Ann Normann, Treebak, Jonas Thue, Barrès, Romain & Zierath, Juleen R, 2023, In: Cell Metabolism. 35, 10, p. 1722-1735.e5 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Role of Diacylglycerol Kinases in Glucose and Energy Homeostasis

    Massart, J. & Zierath, Juleen R, 2019, In: Trends in Endocrinology and Metabolism. 30, 9, p. 603-617

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Role of AMPK in IL-6 release from isolated mouse skeletal muscle

    Glund, S., Treebak, Jonas Thue, Long, Y. C., Barrès, Romain, Viollet, B., Wojtaszewski, Jørgen F P & Zierath, Juleen R, 2008, In: Diabetologia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Reply to ‘Lactate as a major myokine and exerkine’

    Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C. H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, Watt, M. J., Xia, A., Zierath, Juleen R, Goodpaster, B. H. & Snyder, M., 2022, In: Nature Reviews Endocrinology. 18, 11, p. 713 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  23. Published

    Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle

    Lundell, L. S., Massart, J., Altıntaş, Ali, Krook, A. & Zierath, Juleen R, 2019, In: Molecular Metabolism. 20, p. 79-88 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study

    Karlsson, H. K. R., Kasahara, A., Ikeda, M., Chibalin, A. V., Harada, J., Rydén, M., Krook, A., Kato, M., Kubota, K. & Zierath, Juleen R, 2021, In: Metabolism. 118, 7 p., 154726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Quantification of oxidative stress phenotypes based on high-throughput growth profiling of protein kinase and phosphatase knockouts.

    Altıntaş, Ali, 11 Nov 2015, In: FEMS Yeast Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes

    Isidor, Marie Sophie, Winther, Sally, Markussen, L. K., Basse, A. L., Quistorff, B., Nedergaard, J., Emanuelli, Brice & Hansen, Jacob B., 2020, In: FEBS Letters. 594, 7, p. 1218-1225

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes

    Damgaard, Mads Vargas, Jepsen, Sara Lind, Ashcroft, Stephen Paul, Holst, Jens Juul & Treebak, Jonas Thue, 2022, In: Nutrients. 14, 18, 11 p., 3741.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics

    Moreno Justicia, Roger, Gonzalez-Franquesa, A., Stocks, Ben Nicholas & Deshmukh, Atul Shahaji, 2022, In: STAR Protocols. 3, 1, 21 p., 101135.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte Nielsen, 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation

    Batth, Tanveer Singh, Tollenaere, M. A. X., Rüther, P. L., Gonzalez-Franquesa, A., Prabhakar, B. S., Bekker-Jensen, Simon Holst, Deshmukh, Atul Shahaji & Olsen, Jesper Velgaard, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1027-1035

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Post-translational modifications: The signals at the intersection of exercise, glucose uptake and insulin sensitivity

    Stocks, Ben Nicholas & Zierath, Juleen R, 2022, In: Endocrine Reviews. 43, 4, p. 654-677 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action

    Altıntaş, Ali, Liu, J., Fabre, O., Chuang, T., Wang, Y., Sakurai, R., Chehabi, G. N., Barrès, Romain & Rehan, V. K., 2021, In: F A S E B Journal. 35, 7, e21702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Palmitate impairs circadian transcriptomics in muscle cells through histone modification of enhancers

    Pillon, N. J., Puig, L. S., Altıntaş, Ali, Kamble, P. G., Casaní-Galdón, S., Gabriel, B. M., Barrès, Romain, Conesa, A., Chibalin, A. V., Näslund, E., Krook, A. & Zierath, Juleen R, 2022, In: Life Science Alliance. 6, 1, 14 p., e202201598.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Non-cell autonomous mechanisms control mitochondrial gene dysregulation in polycystic ovary syndrome

    Moreno-Asso, A., Altıntaş, Ali, McIlvenna, L. C., Patten, R. K., Botella, J., McAinch, A. J., Rodgers, R. J., Barrès, Romain & Stepto, N. K., 2021, In: Journal of Molecular Endocrinology. 68, 1, p. 63-76

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men

    Dollerup, O. L., Chubanava, Sabina, Agerholm, M., Søndergård, S. D., Altıntaş, Ali, Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde-Jørgensen, H., Lavery, G. G., Barrès, Romain, Larsen, Steen, Prats Gavalda, Clara, Jessen, N. & Treebak, Jonas Thue, 2020, In: Journal of Physiology. 598, 4, p. 731-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journalComment/debateResearch

  38. Published

    NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner

    Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice

    Pendergrast, L. A., Ashcroft, Stephen Paul, Ehrlich, Amy M, Treebak, Jonas Thue, Krook, A., Dollet, L. & Zierath, Juleen R, 2024, In: Metabolism: Clinical and Experimental. 155, 12 p., 155834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care

    Pillon, N. J., Loos, R. J. F., Marshall, S. M. & Zierath, Juleen R, 2021, In: Cell. 184, 6, p. 1530-1544 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Mechanisms preserving insulin action during high dietary fat intake

    Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, K. A., Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, T. S., Hingst, J. R., Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In: Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Mass spectrometry-based proteomics approaches to interrogate skeletal muscle adaptations to exercise

    Cervone, D. T., Moreno Justicia, Roger, Prats Quesada, Júlia & Deshmukh, Atul Shahaji, 2024, In: Scandinavian Journal of Medicine and Science in Sports. 34, 1, 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

    Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Interplay between diet, exercise and the molecular circadian clock in orchestrating metabolic adaptations of adipose tissue

    Dollet, L. & Zierath, Juleen R, 2019, In: Journal of Physiology. 597, 6, p. 1439-1450

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Integrated Liver and Plasma Proteomics in Obese Mice Reveals Complex Metabolic Regulation

    Stocks, Ben Nicholas, Gonzalez-Franquesa, A., Borg, M. L., Björnholm, M., Niu, Lili, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2022, In: Molecular and Cellular Proteomics. 21, 3, 19 p., 100207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Insulin-induced serine 22 phosphorylation of retinoid X receptor alpha is dispensable for adipogenesis in brown adipocytes

    Ardenkjær-Larsen, J., Rupar, K., Snieckute, Goda, Petersen, P. S. S., Villarroel, J., Lundh, M., Barrès, Romain, Rabiee, A. & Emanuelli, Brice, 2020, In: Adipocyte (Philadelphia). 9, 1, p. 142-152 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes

    Isidor, Marie Sophie, Dong, W., Servin-Uribe, R. I., Villarroel, J., Altıntaş, Ali, Ayala-Sumuano, J. T., Varela-Echavarría, A., Barrès, Romain, Stephanopoulos, G., Macotela, Y. & Emanuelli, Brice, 2022, In: International Journal of Obesity. 46, 3, p. 535-543

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Insulin and 5-aminoimidazole-4-carboxamide ribonucleotide (Aicar) differentially regulate the skeletal muscle cell secretome

    Gonzalez-Franquesa, A., Peijs, Lone, Cervone, D. T., Koçana, C., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Proteomes. 9, 3, 16 p., 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression

    Puig, L. S., Pillon, N. J., Naslund, E., Krook, A. & Zierath, Juleen R, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 1, p. E1-E10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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