IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats

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Standard

IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats. / Thomsen, Karen; Aagaard, Niels Kristian; Grønbæk, Henning; Holst, Jens Juul; Jessen, Niels; Frystyk, Jan; Vilstrup, Hendrik.

In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 71, No. 2, 04.2011, p. 150-156.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Thomsen, K, Aagaard, NK, Grønbæk, H, Holst, JJ, Jessen, N, Frystyk, J & Vilstrup, H 2011, 'IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 71, no. 2, pp. 150-156. https://doi.org/10.3109/00365513.2010.547213

APA

Thomsen, K., Aagaard, N. K., Grønbæk, H., Holst, J. J., Jessen, N., Frystyk, J., & Vilstrup, H. (2011). IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats. Scandinavian Journal of Clinical & Laboratory Investigation, 71(2), 150-156. https://doi.org/10.3109/00365513.2010.547213

Vancouver

Thomsen K, Aagaard NK, Grønbæk H, Holst JJ, Jessen N, Frystyk J et al. IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats. Scandinavian Journal of Clinical & Laboratory Investigation. 2011 Apr;71(2):150-156. https://doi.org/10.3109/00365513.2010.547213

Author

Thomsen, Karen ; Aagaard, Niels Kristian ; Grønbæk, Henning ; Holst, Jens Juul ; Jessen, Niels ; Frystyk, Jan ; Vilstrup, Hendrik. / IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats. In: Scandinavian Journal of Clinical & Laboratory Investigation. 2011 ; Vol. 71, No. 2. pp. 150-156.

Bibtex

@article{6dd4500214544757b5454ab1484f9030,
title = "IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats",
abstract = "Clinical or experimentally induced, active inflammation up-regulates the in vivo capacity of urea synthesis (CUNS), which promotes nitrogen removal from the body and metabolic catabolism. We have shown that tumor necrosis factor a (TNF-a) up-regulates CUNS and increases interleukin 6 expression (IL-6) within hours of administration. The described effect of TNF-a on nitrogen homeostasis may, therefore, depend on IL-6.",
keywords = "Acute-Phase Proteins, Animals, Blood Glucose, Corticosterone, Female, Gene Expression Regulation, Glucagon, Humans, Insulin, Interleukin-6, Liver, RNA, Messenger, Rats, Rats, Wistar, Somatomedins, Urea",
author = "Karen Thomsen and Aagaard, {Niels Kristian} and Henning Gr{\o}nb{\ae}k and Holst, {Jens Juul} and Niels Jessen and Jan Frystyk and Hendrik Vilstrup",
year = "2011",
month = apr,
doi = "10.3109/00365513.2010.547213",
language = "English",
volume = "71",
pages = "150--156",
journal = "Scandinavian Journal of Clinical & Laboratory Investigation",
issn = "0036-5513",
publisher = "Taylor & Francis",
number = "2",

}

RIS

TY - JOUR

T1 - IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats

AU - Thomsen, Karen

AU - Aagaard, Niels Kristian

AU - Grønbæk, Henning

AU - Holst, Jens Juul

AU - Jessen, Niels

AU - Frystyk, Jan

AU - Vilstrup, Hendrik

PY - 2011/4

Y1 - 2011/4

N2 - Clinical or experimentally induced, active inflammation up-regulates the in vivo capacity of urea synthesis (CUNS), which promotes nitrogen removal from the body and metabolic catabolism. We have shown that tumor necrosis factor a (TNF-a) up-regulates CUNS and increases interleukin 6 expression (IL-6) within hours of administration. The described effect of TNF-a on nitrogen homeostasis may, therefore, depend on IL-6.

AB - Clinical or experimentally induced, active inflammation up-regulates the in vivo capacity of urea synthesis (CUNS), which promotes nitrogen removal from the body and metabolic catabolism. We have shown that tumor necrosis factor a (TNF-a) up-regulates CUNS and increases interleukin 6 expression (IL-6) within hours of administration. The described effect of TNF-a on nitrogen homeostasis may, therefore, depend on IL-6.

KW - Acute-Phase Proteins

KW - Animals

KW - Blood Glucose

KW - Corticosterone

KW - Female

KW - Gene Expression Regulation

KW - Glucagon

KW - Humans

KW - Insulin

KW - Interleukin-6

KW - Liver

KW - RNA, Messenger

KW - Rats

KW - Rats, Wistar

KW - Somatomedins

KW - Urea

U2 - 10.3109/00365513.2010.547213

DO - 10.3109/00365513.2010.547213

M3 - Journal article

C2 - 21190512

VL - 71

SP - 150

EP - 156

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

SN - 0036-5513

IS - 2

ER -

ID: 38531833