- 2006
- Published
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Metabolic adaptations through the PGC-1α and SIRT1 pathways
Rodgers, J. T., Lerin, C., Gerhart-Hines, Zach & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity
Cantó, C., Gerhart-Hines, Zach, Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Zach, Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells
Suchankova, G., Nelson, L. E., Gerhart-Hines, Zach, Kelly, M., Gauthier, M. S., Saha, A. K., Ido, Y., Puigserver, P. & Ruderman, N. B., 23 Jan 2009, In: Biochemical and Biophysical Research Communications. 378, 4, p. 836-841 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
Dominy, J. E., Lee, Y., Gerhart-Hines, Zach & Puigserver, P., Aug 2010, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 8, p. 1676-1683 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 2011
- Published
Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming
Dominy, J. E., Gerhart-Hines, Zach & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD +
Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
A metabolic prosurvival role for PML in breast cancer
Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Neuronal apoptosis in the neonates born to preeclamptic mothers
Cosar, H., Ozer, E., Topel, Hande, Kahramaner, Z., Turkoglu, E., Erdemir, A., Sutcuoglu, S., Bagriyanik, A. & Ozer, E. A., Jul 2013, In: Journal of Maternal-Fetal Medicine. 26, 11, p. 1143-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intraoperative vector flow imaging of the heart
Hansen, Kristoffer Lindskov, Moller-Sorensen, H., Pedersen, M. M., Kjærgaard, Jesper, Nilsson, J. C., Lund, Jens, Nielsen, Michael Bachmann & Jensen, J. A., 2013, 2013 IEEE International Ultrasonics Symposium, IUS 2013. p. 1745-1748 4 p. 6725113. (IEEE International Ultrasonics Symposium, IUS).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex
Lim, J. H., Gerhart-Hines, Zach, Dominy, J. E., Lee, Y., Kim, S., Tabata, M., Xiang, Y. K. & Puigserver, P., 8 Mar 2013, In: Journal of Biological Chemistry. 288, 10, p. 7117-7126 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics and epigenetics of liver cancer
Ozen, C., Yildiz, G., Dagcan, A. T., Cevik, D., Ors, A., Keles, U., Topel, Hande & Ozturk, M., 25 May 2013, In: New Biotechnology. 30, 4, p. 381-4 4 p.Research output: Contribution to journal › Review › Research › peer-review
- 2014
- Published
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo
Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Heparin treatment increases thioredoxin interacting protein expression in hepatocellular carcinoma cells
Gunes, A., Iscan, E., Topel, Hande, Avci, S. T., Gumustekin, M., Erdal, E. & Atabey, N., Aug 2015, In: The International Journal of Biochemistry & Cell Biology. 65, p. 169-81 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First report on intraoperative vector flow imaging of the heart among patients with healthy and diseased aortic valves
Hansen, Kristoffer Lindskov, Møller-Sørensen, H., Pedersen, M. M., Hansen, P. M., Kjærgaard, Jesper, Lund, Jens, Nilsson, J. C., Jensen, J. A. & Nielsen, Michael Bachmann, 1 Feb 2015, In: Ultrasonics. 56, p. 243-250 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge
Emmett, M. J., Lim, H., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, Tao, Sims, C. A., Baur, J. A., Pei, L., Won, K., Seale, P., Gerhart-Hines, Zach & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Keeping fat on time: Circadian control of adipose tissue
Ninel Hansen, S., Peics, J. & Gerhart-Hines, Zach, Nov 2017, In: Experimental Cell Research. 360, 1, p. 31-34 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Signaling Pathways as Potential Therapeutic Targets in Hepatocarcinogenesis
Yılmaz, Y., Güneş, A., Topel, Hande & Atabey, N., Sep 2017, In: Journal of Gastrointestinal Cancer. 48, 3, p. 225-237 13 p.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
Agudelo, L. Z., Ferreira, D. M. S., Cervenka, I., Bryzgalova, G., Dadvar, S., Jannig, P. R., Pettersson-Klein, A. T., Lakshmikanth, T., Sustarsic, E. G., Porsmyr-Palmertz, M., Correia, J. C., Izadi, M., Martínez-Redondo, V., Ueland, P. M., Midttun, Ø., Gerhart-Hines, Zach, Brodin, P., Pereira, T., Berggren, P. & Ruas, J. L., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 378-392.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma
Korhan, P., Yılmaz, Y., Bağırsakçı, E., Güneş, A., Topel, Hande, Carr, B. I. & Atabey, N., 2018, In: Canadian Journal of Gastroenterology. 2018, p. 7568742Research output: Contribution to journal › Review › Research › peer-review
- Published
Brown fat: the biological furnace that could burn away obesity
Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.Research output: Contribution to journal › Journal article › Research
- Published
Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism
Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, Fei, Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Zach, Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
Nielsen, K. N., Peics, J., Ma, Tao, Karavaeva, Iuliia, Dall, M., Chubanava, Sabina, Basse, A. L., Dmytriyeva, O., Treebak, Jonas Thue & Gerhart-Hines, Zach, May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
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A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
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NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
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