Gerhart-Hines Group

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  1. Published

    Autocrine negative feed-back regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

    Husted, Anna Sofie, Ekberg, J. H., Tripp, E., Nissen, T. A. D., Meijnikman, S., O'Brien, S. L., Ulven, Trond, Acherman, Y., Bruin, S. C., Nieuwdorp, M., Gerhart-Hines, Zach, Calebiro, D., Dragsted, Lars Ove & Schwartz, Thue W., 2020, In: Molecular Metabolism. 42, 10 p., 101103.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

    Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling

    Khatib-Massalha, E., Bhattacharya, S., Massalha, H., Biram, A., Golan, K., Kollet, O., Kumari, A., Avemaria, F., Petrovich-Kopitman, E., Gur-Cohen, S., Itkin, T., Brandenburger, I., Spiegel, A., Shulman, Z., Gerhart-Hines, Z., Itzkovitz, S., Gunzer, M., Offermanns, S., Alon, R., Ariel, A. & 1 others, Lapidot, T., 2020, In: Nature Communications. 11, 1, 18 p., 3547.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

    Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma

    Korhan, P., Yılmaz, Y., Bağırsakçı, E., Güneş, A., Topel, Hande, Carr, B. I. & Atabey, N., 2018, In: Canadian Journal of Gastroenterology. 2018, p. 7568742

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

    Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex

    Lim, J. H., Gerhart-Hines, Zach, Dominy, J. E., Lee, Y., Kim, S., Tabata, M., Xiang, Y. K. & Puigserver, P., 8 Mar 2013, In: Journal of Biological Chemistry. 288, 10, p. 7117-7126 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R

    Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Overlooked confounding in studies of metabolite salts

    Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  12. Published

    Brown fat: the biological furnace that could burn away obesity

    Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.

    Research output: Contribution to journal › Journal article › Research

  13. Published

    Physiological protection against weight gain: evidence from overfeeding studies and future directions

    Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Har du let eller svært ved at tage på? Måske skyldes det kalorierne i toilettet

    Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 1 Oct 2020, Videnskab.dk, ForskerZonen.

    Research output: Other contribution › Net publication - Internet publication › Communication

  15. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The unidentified hormonal defense against weight gain

    Lund, Jens, Lund, Camilla, Morville, T. H. & Clemmensen, Christoffer, 2020, In: PLOS Biology. 18, 2, 14 p., e3000629.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Is lactate a driver of skin burn-induced adipose browning?

    Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  18. Published

    Naturlig tyndhed: En misforstået og mystisk form for undervægt

    Lund, Jens, 2020, In: Diætisten. 166, p. 33-34 2 p.

    Research output: Contribution to journal › Journal article › Communication

  19. Published

    Outrunning obesity with Lac-Phe?

    Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  20. Published

    Tracing the biological roots of obesity resistance in humans

    Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  21. Published

    Role of Energy Excretion in Human Body Weight Regulation

    Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    MCT1 helps brown fat suck up succinate

    Lund, Jens, Isidor, Marie Sophie & Gerhart-Hines, Zach, 2024, In: Nature Metabolism. 6, p. 387–388

    Research output: Contribution to journal › Letter › Research › peer-review

  23. Published

    Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue

    Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Cold-induction of afadin in brown fat supports its thermogenic capacity

    Lundh, M., Altıntaş, Ali, Tozzi, M., Fabre, O., Ma, Tao, Shamsi, F., Gerhart-Hines, Zach, Barrès, Romain, Tseng, Y. & Emanuelli, Brice, 2021, In: Scientific Reports. 11, 11 p., 9794.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism

    Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, Fei, Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Zach, Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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