Grarup Group

  1. Published

    Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

    Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, Nielsen, Rasmus, Linneberg, Allan René, Olafsson, I., Eyjolfsson, G. I., Jørgensen, T., Wang, J., Hansen, Torben, Thorsteinsdottir, U., Stefánsson, K. & Pedersen, Oluf Borbye, 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

    Grarup, Niels, Sandholt, C. H., Hansen, Torben & Pedersen, Oluf Borbye, Aug 2014, In: Diabetologia. 57, 8, p. 1528-41 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    A decade of genome discoveries in type 2 diabetes and metabolism

    Grarup, Niels, 2020, University of Copenhagen. 72 p.

    Research output: Book/ReportDoctoral thesisResearch

  4. Published

    Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: A study of 15,734 Danish subjects

    Grarup, Niels, Stender-Petersen, K. L., Andersson, E. A., Jorgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Physiologic characterization of type 2 diabetes-related loci

    Grarup, Niels, Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

    Grarup, Niels, Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

    Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

    Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

    Grarup, Niels, Andersen, G., Krarup, N. T., Albrechtsen, Anders, Schmitz, O., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 9, p. 2534-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

    Grarup, Niels, Overvad, M., Sparsø, T., Witte, D. R., Pisinger, C., Jørgensen, T., Yamauchi, T., Hara, K., Maeda, S., Kadowaki, T., Hansen, T. & Pedersen, Oluf Borbye, 2011, In: Diabetologica. 54, 4, p. 789-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review