Grarup Group

  1. 2011
  2. Published

    Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome

    Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Kim, S. Y., Korneliussen, Thorfinn Sand, Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Feder, A. F., Grarup, Niels, Jørgensen, T., Jiang, T., Witte, D. R., Sandbæk, A., Hellmann, I., Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: P L o S Genetics. 7, 10, 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans

    Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

    Grarup, Niels, Overvad, M., Sparsø, T., Witte, D. R., Pisinger, C., Jørgensen, T., Yamauchi, T., Hara, K., Maeda, S., Kadowaki, T., Hansen, T. & Pedersen, Oluf Borbye, 2011, In: Diabetologica. 54, 4, p. 789-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2010
  6. Published

    Physiologic characterization of type 2 diabetes-related loci

    Grarup, Niels, Sparsø, T. & Hansen, Torben, 1 Dec 2010, In: Current Diabetes Reports. 10, 6, p. 485-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

    Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. & 26 others, Andersen, G., Witte, D. R., Jørgensen, T., Lauritzen, T., Sandbæk, A., Hansen, T., Ohshige, T., Omori, S., Saito, I., Kaku, K., Hirose, H., So, W., Beury, D., Chan, J. C. N., Park, K. S., Tai, E. S., Ito, C., Tanaka, Y., Kashiwagi, A., Kawamori, R., Kasuga, M., Froguel, P., Pedersen, Oluf Borbye, Kamatani, N., Nakamura, Y. & Kadowaki, T., 1 Oct 2010, In: Nature Genetics. 42, 10, p. 864-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight

    Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Faerch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 1 Sep 2010, In: Diabetologia. 53, 9, p. 1908-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

    Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J-P. P. M., Kranendonk, S. E., Zeebregts, C. J. A. M., van Sterkenburg, S. M., Geelkerken, R. H., van Rij, A. M., Williams, M. J. A., Boll, A. P. M., Kostic, J. P., Jonasdottir, A., Jonasdottir, A., Walters, G. B., Masson, G., Sulem, P., Saemundsdottir, J. & 82 others, Mouy, M., Magnusson, K. P., Tromp, G., Elmore, J. R., Sakalihasan, N., Limet, R., Defraigne, J., Ferrell, R. E., Ronkainen, A., Ruigrok, Y. M., Wijmenga, C., Grobbee, D. E., Shah, S. H., Granger, C. B., Quyyumi, A. A., Vaccarino, V., Patel, R. S., Zafari, A. M., Levey, A. I., Austin, H., Girelli, D., Pignatti, P. F., Olivieri, O., Martinelli, N., Malerba, G., Trabetti, E., Becker, L. C., Becker, D. M., Reilly, M. P., Rader, D. J., Mueller, T., Dieplinger, B., Haltmayer, M., Urbonavicius, S., Lindblad, B., Gottsäter, A., Gaetani, E., Pola, R., Wells, P., Rodger, M., Forgie, M., Langlois, N., Corral, J., Vasquez, V., Fontcuberta, J., España, F., Grarup, Niels, Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye, Aben, K. K., de Graaf, J., Holewijn, S., Folkersen, L., Franco-Cereceda, A., Eriksson, P., Collier, D. A., Stefansson, H., Steinthorsdottir, V., Rafnar, T., Valdimarsson, E. M., Magnadottir, H. B., Sveinbjornsdottir, S., Olafsson, I., Magnusson, M. K., Palmason, R., Haraldsdottir, V., Andersen, K., Onundarson, P. T., Thorgeirsson, G., Kiemeney, L. A., Powell, J. T., Carey, D. J., Kuivaniemi, H., Lindholt, J. S., Jones, G. T., Kong, A., Blankensteijn, J. D., Matthiasson, S. E., Thorsteinsdottir, U. & Stefansson, K., 1 Aug 2010, In: Nature Genetics. 42, 8, p. 692-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

    Boesgaard, T. W., Grarup, Niels, Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 1 Aug 2010, In: Diabetologia. 53, 8, p. 1647-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M. & 31 others, Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bengtsson Boström, K., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Grarup, Niels, Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye & MAGIC investigators, M. I., 1 Jul 2010, In: Nature Genetics. 42, 7, p. 579-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

    Saxena, R., Hivert, M-F., Langenberg, C., Tanaka, T., Pankow, J. S., Vollenweider, P., Lyssenko, V., Bouatia-Naji, N., Dupuis, J., Jackson, A. U., Kao, W. H. L., Li, M., Glazer, N. L., Manning, A. K., Luan, J., Stringham, H. M., Prokopenko, I., Johnson, T., Grarup, N., Boesgaard, T. W. & 31 others, Lecoeur, C., Shrader, P., O'Connell, J., Ingelsson, E., Couper, D. J., Rice, K., Song, K., Andreasen, C. H., Dina, C., Köttgen, A., Le Bacquer, O., Pattou, F., Taneera, J., Steinthorsdottir, V., Rybin, D., Ardlie, K., Sampson, M., Qi, L., van Hoek, M., Weedon, M. N., Aulchenko, Y. S., Voight, B. F., Grallert, H., Balkau, B., Bergman, R. N., Borch-Johnsen, K., Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye & GIANT Consortium, G. C., 1 Feb 2010, In: Nature Genetics. 42, 2, p. 142-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review