Genetic aspects of non-alcoholic fatty liver disease (NAFLD)
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Genetic aspects of non-alcoholic fatty liver disease (NAFLD). / Stender, Stefan; Grarup, Niels; Hansen, Torben.
The Human Gut-Liver-Axis in Health and Disease. Springer, 2018. p. 195-206.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TY - CHAP
T1 - Genetic aspects of non-alcoholic fatty liver disease (NAFLD)
AU - Stender, Stefan
AU - Grarup, Niels
AU - Hansen, Torben
PY - 2018
Y1 - 2018
N2 - Non-alcoholic fatty liver disease (NAFLD) is a buildup of excessive fat in the liver that can lead to liver damage resembling the damage caused by alcohol abuse, but that occurs in people who do not drink heavily. The disease is of complex and of multifactorial origin. Insulin resistance and obesity are considered major risk factors for the development and progression of NAFLD, however, an important genetic component has been demonstrated. Recent phenotypic characterization of a large number of individuals with NAFLD and developments in genotyping technology has allowed for identification of common genetic variants associating with NAFLD. This book chapter focuses on recent insights into the genetics of NAFLD and directions for future genetic studies are discussed.
AB - Non-alcoholic fatty liver disease (NAFLD) is a buildup of excessive fat in the liver that can lead to liver damage resembling the damage caused by alcohol abuse, but that occurs in people who do not drink heavily. The disease is of complex and of multifactorial origin. Insulin resistance and obesity are considered major risk factors for the development and progression of NAFLD, however, an important genetic component has been demonstrated. Recent phenotypic characterization of a large number of individuals with NAFLD and developments in genotyping technology has allowed for identification of common genetic variants associating with NAFLD. This book chapter focuses on recent insights into the genetics of NAFLD and directions for future genetic studies are discussed.
U2 - 10.1007/978-3-319-98890-0_12
DO - 10.1007/978-3-319-98890-0_12
M3 - Book chapter
AN - SCOPUS:85078156435
SN - 9783319988894
SP - 195
EP - 206
BT - The Human Gut-Liver-Axis in Health and Disease
PB - Springer
ER -
ID: 347797338