Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery. / Aukan, Marthe Isaksen; Skårvold, Silje; Brandsaeter, Ingrid Øfsti; Rehfeld, Jens Frederik; Holst, Jens Juul; Nymo, Siren; Coutinho, Silvia; Martins, Catia.

In: Obesity, Vol. 31, No. 2, 2023, p. 399-411.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Aukan, MI, Skårvold, S, Brandsaeter, IØ, Rehfeld, JF, Holst, JJ, Nymo, S, Coutinho, S & Martins, C 2023, 'Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery', Obesity, vol. 31, no. 2, pp. 399-411. https://doi.org/10.1002/oby.23655

APA

Aukan, M. I., Skårvold, S., Brandsaeter, I. Ø., Rehfeld, J. F., Holst, J. J., Nymo, S., Coutinho, S., & Martins, C. (2023). Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery. Obesity, 31(2), 399-411. https://doi.org/10.1002/oby.23655

Vancouver

Aukan MI, Skårvold S, Brandsaeter IØ, Rehfeld JF, Holst JJ, Nymo S et al. Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery. Obesity. 2023;31(2):399-411. https://doi.org/10.1002/oby.23655

Author

Aukan, Marthe Isaksen ; Skårvold, Silje ; Brandsaeter, Ingrid Øfsti ; Rehfeld, Jens Frederik ; Holst, Jens Juul ; Nymo, Siren ; Coutinho, Silvia ; Martins, Catia. / Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery. In: Obesity. 2023 ; Vol. 31, No. 2. pp. 399-411.

Bibtex

@article{7f5ebf3317eb4038b1ca184119f6f6f0,
title = "Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery",
abstract = "OBJECTIVE: The aim of this study was to compare changes in gastrointestinal hormones and appetite ratings after a similar weight loss induced by a very low-energy diet alone or in combination with sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB).METHODS: Patients with severe obesity scheduled for SG (n = 15) and RYGB (n = 14) and 15 controls (very low-energy diet alone) were recruited. Body weight/composition, plasma concentrations of {\ss}-hydroxybutyric acid, acylated ghrelin, total glucagon-like peptide-1, total peptide YY, cholecystokinin, and ratings of hunger, fullness, desire to eat, and prospective food consumption were measured pre- and postprandially, before and after 10 weeks of intervention.RESULTS: Changes in body weight/composition and level of ketosis were similar across groups. In SG and RYGB, basal and postprandial acylated ghrelin declined, and postprandial glucagon-like peptide-1 increased, both significantly more compared with controls. Postprandial peptide YY increased in all groups. Overall, postprandial hunger decreased, and postprandial fullness increased. But ratings of desire to eat and prospective food consumption were more favorable after both surgeries compared with controls.CONCLUSIONS: Weight loss with SG and RYGB leads to more favorable changes in gastrointestinal hormones compared with diet alone, although ratings of appetite were reduced across all groups.",
author = "Aukan, {Marthe Isaksen} and Silje Sk{\aa}rvold and Brandsaeter, {Ingrid {\O}fsti} and Rehfeld, {Jens Frederik} and Holst, {Jens Juul} and Siren Nymo and Silvia Coutinho and Catia Martins",
note = "{\textcopyright} 2022 The Authors. Obesity published by Wiley Periodicals LLC on behalf of The Obesity Society.",
year = "2023",
doi = "10.1002/oby.23655",
language = "English",
volume = "31",
pages = "399--411",
journal = "Obesity",
issn = "1930-7381",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery

AU - Aukan, Marthe Isaksen

AU - Skårvold, Silje

AU - Brandsaeter, Ingrid Øfsti

AU - Rehfeld, Jens Frederik

AU - Holst, Jens Juul

AU - Nymo, Siren

AU - Coutinho, Silvia

AU - Martins, Catia

N1 - © 2022 The Authors. Obesity published by Wiley Periodicals LLC on behalf of The Obesity Society.

PY - 2023

Y1 - 2023

N2 - OBJECTIVE: The aim of this study was to compare changes in gastrointestinal hormones and appetite ratings after a similar weight loss induced by a very low-energy diet alone or in combination with sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB).METHODS: Patients with severe obesity scheduled for SG (n = 15) and RYGB (n = 14) and 15 controls (very low-energy diet alone) were recruited. Body weight/composition, plasma concentrations of ß-hydroxybutyric acid, acylated ghrelin, total glucagon-like peptide-1, total peptide YY, cholecystokinin, and ratings of hunger, fullness, desire to eat, and prospective food consumption were measured pre- and postprandially, before and after 10 weeks of intervention.RESULTS: Changes in body weight/composition and level of ketosis were similar across groups. In SG and RYGB, basal and postprandial acylated ghrelin declined, and postprandial glucagon-like peptide-1 increased, both significantly more compared with controls. Postprandial peptide YY increased in all groups. Overall, postprandial hunger decreased, and postprandial fullness increased. But ratings of desire to eat and prospective food consumption were more favorable after both surgeries compared with controls.CONCLUSIONS: Weight loss with SG and RYGB leads to more favorable changes in gastrointestinal hormones compared with diet alone, although ratings of appetite were reduced across all groups.

AB - OBJECTIVE: The aim of this study was to compare changes in gastrointestinal hormones and appetite ratings after a similar weight loss induced by a very low-energy diet alone or in combination with sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB).METHODS: Patients with severe obesity scheduled for SG (n = 15) and RYGB (n = 14) and 15 controls (very low-energy diet alone) were recruited. Body weight/composition, plasma concentrations of ß-hydroxybutyric acid, acylated ghrelin, total glucagon-like peptide-1, total peptide YY, cholecystokinin, and ratings of hunger, fullness, desire to eat, and prospective food consumption were measured pre- and postprandially, before and after 10 weeks of intervention.RESULTS: Changes in body weight/composition and level of ketosis were similar across groups. In SG and RYGB, basal and postprandial acylated ghrelin declined, and postprandial glucagon-like peptide-1 increased, both significantly more compared with controls. Postprandial peptide YY increased in all groups. Overall, postprandial hunger decreased, and postprandial fullness increased. But ratings of desire to eat and prospective food consumption were more favorable after both surgeries compared with controls.CONCLUSIONS: Weight loss with SG and RYGB leads to more favorable changes in gastrointestinal hormones compared with diet alone, although ratings of appetite were reduced across all groups.

U2 - 10.1002/oby.23655

DO - 10.1002/oby.23655

M3 - Journal article

C2 - 36536482

VL - 31

SP - 399

EP - 411

JO - Obesity

JF - Obesity

SN - 1930-7381

IS - 2

ER -

ID: 331584741