- Published
Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism
Abdelmoez, A. M., Puig, L. S., Smith, J. A. B., Gabriel, B. M., Savikj, M., Dollet, L., Chibalin, A. V., Krook, A., Zierath, Juleen R & Pillon, N. J., 2020, In: American Journal of Physiology: Cell Physiology. 318, 3, p. C615-C626 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
Agudelo, L. Z., Ferreira, D. M. S., Cervenka, I., Bryzgalova, G., Dadvar, S., Jannig, P. R., Pettersson-Klein, A. T., Lakshmikanth, T., Sustarsic, E. G., Porsmyr-Palmertz, M., Correia, J. C., Izadi, M., Martínez-Redondo, V., Ueland, P. M., Midttun, Ø., Gerhart-Hines, Zach, Brodin, P., Pereira, T., Berggren, P. & Ruas, J. L., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 378-392.e5Research output: Contribution to journal › Journal article › Research › peer-review
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PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
c-Met activation promotes extravasation of hepatocellular carcinoma cells into 3D-cultured hepatocyte cells in lab-on-a-chip device
Bagci, G., Comez, D., Topel, Hande, Yilmaz, Y., Bagirsakci, E., Gunes, A., Batı Ayaz, G., Tahmaz, I., Bilgen, M., Solmaz, G., Pesen Okvur, D. & Atabey, N., Dec 2023, In: B B A - Molecular Cell Research. 1870, 8, p. 119557Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Simvastatin Treatment on Mitochondrial Function and Inflammatory Status of Human White Adipose Tissue
Bager Christensen, I., Blom, Ida, Dohlmann, T. L., Finger, Fabian Michael, Helge, Jørn Wulff, Gerhart-Hines, Zach, Dela, Flemming & Larsen, Steen, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 10, p. e916-e922 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner
Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chasing the hunger-suppressive signals of human exercise
Brunetta, H. S. & Lund, Jens, 2023, In: Journal of Physiology. 601, 16, p. 3441-3442 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity
Cantó, C., Gerhart-Hines, Zach, Feige, J. N., Lagouge, M., Noriega, L., Milne, J. C., Elliott, P. J., Puigserver, P. & Auwerx, J., 23 Apr 2009, In: Nature. 458, 7241, p. 1056-1060 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A metabolic prosurvival role for PML in breast cancer
Carracedo, A., Weiss, D., Leliaert, A. K., Bhasin, M., De Boer, V. C. J., Laurent, G., Adams, A. C., Sundvall, M., Song, S. J., Ito, K., Finley, L. S., Egia, A., Libermann, T., Gerhart-Hines, Zach, Puigserver, P., Haigis, M. C., Maratos-Flier, E., Richardson, A. L., Schafer, Z. T. & Pandolfi, P. P., 4 Sep 2012, In: Journal of Clinical Investigation. 122, 9, p. 3088-3100 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice
Correia, C. M., Præstholm, S. M., Havelund, J. F., Boel, Felix, Siersbæk, M. S., Ebbesen, M. F., Gerhart-Hines, Zach, Heeren, J., Brewer, J., Larsen, Steen, Blagoev, B., Færgeman, N. J. & Grøntved, L., 2023, In: Endocrinology. 164, 10, p. 1-17 164.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuronal apoptosis in the neonates born to preeclamptic mothers
Cosar, H., Ozer, E., Topel, Hande, Kahramaner, Z., Turkoglu, E., Erdemir, A., Sutcuoglu, S., Bagriyanik, A. & Ozer, E. A., Jul 2013, In: Journal of Maternal-Fetal Medicine. 26, 11, p. 1143-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine
Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, , 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
Dollet, L., Lundell, L. S., Chibalin, A. V., Pendergrast, L. A., Pillon, N. J., Lansbury, Elizabeth Laura, Elmastas, M., Frendo-Cumbo, S., Jalkanen, J., de Castro Barbosa, T., Cervone, D. T., Caidahl, K., Dmytriyeva, O., Deshmukh, Atul Shahaji, Barrès, Romain, Rydén, M., Wallberg-Henriksson, H., Zierath, Juleen R & Krook, A., 2024, In: Cell Reports Medicine. 5, 1, 20 p., 101348.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming
Dominy, J. E., Gerhart-Hines, Zach & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
Dominy, J. E., Lee, Y., Gerhart-Hines, Zach & Puigserver, P., Aug 2010, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1804, 8, p. 1676-1683 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge
Emmett, M. J., Lim, H., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, Tao, Sims, C. A., Baur, J. A., Pei, L., Won, K., Seale, P., Gerhart-Hines, Zach & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice
Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo
Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations
Gerhart-Hines, Zach & Loos, Ruth, 2023, In: Current Opinion in Genetics and Development. 83, 102117.Research output: Contribution to journal › Editorial › Research
- Published
The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD +
Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research
Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, , 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.Research output: Contribution to journal › Comment/debate › Research
- Published
Heparin treatment increases thioredoxin interacting protein expression in hepatocellular carcinoma cells
Gunes, A., Iscan, E., Topel, Hande, Avci, S. T., Gumustekin, M., Erdal, E. & Atabey, N., Aug 2015, In: The International Journal of Biochemistry & Cell Biology. 65, p. 169-81 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First report on intraoperative vector flow imaging of the heart among patients with healthy and diseased aortic valves
Hansen, Kristoffer Lindskov, Møller-Sørensen, H., Pedersen, M. M., Hansen, P. M., Kjærgaard, Jesper, Lund, Jens, Nilsson, J. C., Jensen, J. A. & Nielsen, Michael Bachmann, 1 Feb 2015, In: Ultrasonics. 56, p. 243-250 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intraoperative vector flow imaging of the heart
Hansen, Kristoffer Lindskov, Moller-Sorensen, H., Pedersen, M. M., Kjærgaard, Jesper, Nilsson, J. C., Lund, Jens, Nielsen, Michael Bachmann & Jensen, J. A., 2013, 2013 IEEE International Ultrasonics Symposium, IUS 2013. p. 1745-1748 4 p. 6725113. (IEEE International Ultrasonics Symposium, IUS).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Autocrine negative feed-back regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT
Husted, Anna Sofie, Ekberg, J. H., Tripp, E., Nissen, T. A. D., Meijnikman, S., O'Brien, S. L., Ulven, Trond, Acherman, Y., Bruin, S. C., Nieuwdorp, M., Gerhart-Hines, Zach, Calebiro, D., Dragsted, Lars Ove & Schwartz, Thue W., 2020, In: Molecular Metabolism. 42, 10 p., 101103.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis
Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice
Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling
Khatib-Massalha, E., Bhattacharya, S., Massalha, H., Biram, A., Golan, K., Kollet, O., Kumari, A., Avemaria, F., Petrovich-Kopitman, E., Gur-Cohen, S., Itkin, T., Brandenburger, I., Spiegel, A., Shulman, Z., Gerhart-Hines, Z., Itzkovitz, S., Gunzer, M., Offermanns, S., Alon, R., Ariel, A. & 1 others, , 2020, In: Nature Communications. 11, 1, 18 p., 3547.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance
Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, , 2021, In: Nature Communications. 12, 9 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma
Korhan, P., Yılmaz, Y., Bağırsakçı, E., Güneş, A., Topel, Hande, Carr, B. I. & Atabey, N., 2018, In: Canadian Journal of Gastroenterology. 2018, p. 7568742Research output: Contribution to journal › Review › Research › peer-review
- Published
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex
Lim, J. H., Gerhart-Hines, Zach, Dominy, J. E., Lee, Y., Kim, S., Tabata, M., Xiang, Y. K. & Puigserver, P., 8 Mar 2013, In: Journal of Biological Chemistry. 288, 10, p. 7117-7126 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overlooked confounding in studies of metabolite salts
Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Brown fat: the biological furnace that could burn away obesity
Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.Research output: Contribution to journal › Journal article › Research
- Published
Physiological protection against weight gain: evidence from overfeeding studies and future directions
Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.Research output: Contribution to journal › Review › Research › peer-review
- Published
Har du let eller svært ved at tage på? Måske skyldes det kalorierne i toilettet
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 1 Oct 2020, Videnskab.dk, ForskerZonen.Research output: Other contribution › Net publication - Internet publication › Communication
- Published
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions
Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, , 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The unidentified hormonal defense against weight gain
Lund, Jens, Lund, Camilla, Morville, T. H. & Clemmensen, Christoffer, 2020, In: PLOS Biology. 18, 2, 14 p., e3000629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is lactate a driver of skin burn-induced adipose browning?
Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Naturlig tyndhed: En misforstået og mystisk form for undervægt
Lund, Jens, 2020, In: Diætisten. 166, p. 33-34 2 p.Research output: Contribution to journal › Journal article › Communication
- Published
Outrunning obesity with Lac-Phe?
Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Tracing the biological roots of obesity resistance in humans
Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Role of Energy Excretion in Human Body Weight Regulation
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MCT1 helps brown fat suck up succinate
Lund, Jens, Isidor, Marie Sophie & Gerhart-Hines, Zach, 2024, In: Nature Metabolism. 6, p. 387–388Research output: Contribution to journal › Letter › Research › peer-review
- Published
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue
Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cold-induction of afadin in brown fat supports its thermogenic capacity
Lundh, M., Altıntaş, Ali, Tozzi, M., Fabre, O., Ma, Tao, Shamsi, F., Gerhart-Hines, Zach, Barrès, Romain, Tseng, Y. & Emanuelli, Brice, 2021, In: Scientific Reports. 11, 11 p., 9794.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism
Lynes, M. D., Shamsi, F., Sustarsic, E. G., Leiria, L. O., Wang, C. H., Su, S. C., Huang, T. L., Gao, Fei, Narain, N. R., Chen, E. Y., Cypess, A. M., Schulz, T. J., Gerhart-Hines, Zach, Kiebish, M. A. & Tseng, Y. H., 2018, In: Cell Reports. 24, 3, p. 781-790 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
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A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
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NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Research output: Contribution to journal › Journal article › Research › peer-review
Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
Research output: Contribution to journal › Journal article › Research › peer-review
MCT1 helps brown fat suck up succinate
Research output: Contribution to journal › Letter › Research › peer-review