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Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
Dollet, L., Lundell, L. S., Chibalin, A. V., Pendergrast, L. A., Pillon, N. J., Lansbury, Elizabeth Laura, Elmastas, M., Frendo-Cumbo, S., Jalkanen, J., de Castro Barbosa, T., Cervone, D. T., Caidahl, K., Dmytriyeva, O., Deshmukh, Atul Shahaji, Barrès, Romain, Rydén, M., Wallberg-Henriksson, H., Zierath, Juleen R & Krook, A., 2024, In: Cell Reports Medicine. 5, 1, 20 p., 101348.Research output: Contribution to journal › Journal article › Research › peer-review
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Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus
de Guia, R. M., Hassing, Anna Skab, Skov, Louise Julie, Ratner, C., Plucinska, Kaja, Madsen, S., Diep, T. A., dela Cruz, Gelo, Trammell, Sam, Sustarsic, E. G., Emanuelli, Brice, Gillum, M. P., Gerhart-Hines, Zach, Holst, Birgitte & Treebak, Jonas Thue, 2020, In: Acta Physiologica. 228, 4Research output: Contribution to journal › Journal article › Research › peer-review
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First report on intraoperative vector flow imaging of the heart among patients with healthy and diseased aortic valves
Hansen, Kristoffer Lindskov, Møller-Sørensen, H., Pedersen, M. M., Hansen, P. M., Kjærgaard, Jesper, Lund, Jens, Nilsson, J. C., Jensen, J. A. & Nielsen, Michael Bachmann, 1 Feb 2015, In: Ultrasonics. 56, p. 243-250 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fueling the fire of adipose thermogenesis
Wolfrum, C. & Gerhart-Hines, Zach, 2022, In: Science. 375, 6586, p. 1229-1231 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Full activation of thermogenesis in brown adipocytes requires Basigin action
Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691Research output: Contribution to journal › Journal article › Research › peer-review
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Genetics and epigenetics of liver cancer
Ozen, C., Yildiz, G., Dagcan, A. T., Cevik, D., Ors, A., Keles, U., Topel, Hande & Ozturk, M., 25 May 2013, In: New Biotechnology. 30, 4, p. 381-4 4 p.Research output: Contribution to journal › Review › Research › peer-review
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Har du let eller svært ved at tage på? Måske skyldes det kalorierne i toilettet
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 1 Oct 2020, Videnskab.dk, ForskerZonen.Research output: Other contribution › Net publication - Internet publication › Communication
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Heparin treatment increases thioredoxin interacting protein expression in hepatocellular carcinoma cells
Gunes, A., Iscan, E., Topel, Hande, Avci, S. T., Gumustekin, M., Erdal, E. & Atabey, N., Aug 2015, In: The International Journal of Biochemistry & Cell Biology. 65, p. 169-81 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge
Emmett, M. J., Lim, H., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, Tao, Sims, C. A., Baur, J. A., Pei, L., Won, K., Seale, P., Gerhart-Hines, Zach & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448Research output: Contribution to journal › Journal article › Research › peer-review
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Housing temperature influences exercise training adaptations in mice
Raun, Steffen Henning, Henriquez-Olguín, Carlos, Karavaeva, Iuliia, Ali, Mona Sadek, Møller, Lisbeth L V, Kot, Witold, Castro-Mejía, J. L., Nielsen, Dennis Sandris, Gerhart-Hines, Zach, Richter, Erik A. & Sylow, Lykke, 2020, In: Nature Communications. 11, 16 p., 1560.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Zach, Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, Astrid Elisabeth Bruun, Olsen, B. H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, S., Bendtsen, Flemming & Dela, Flemming, 2022, In: Nature Communications. 13, 15 p., 2931.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intraoperative vector flow imaging of the heart
Hansen, Kristoffer Lindskov, Moller-Sorensen, H., Pedersen, M. M., Kjærgaard, Jesper, Nilsson, J. C., Lund, Jens, Nielsen, Michael Bachmann & Jensen, J. A., 2013, 2013 IEEE International Ultrasonics Symposium, IUS 2013. p. 1745-1748 4 p. 6725113. (IEEE International Ultrasonics Symposium, IUS).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Is lactate a driver of skin burn-induced adipose browning?
Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.Research output: Contribution to journal › Comment/debate › Research
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Keeping fat on time: Circadian control of adipose tissue
Ninel Hansen, S., Peics, J. & Gerhart-Hines, Zach, Nov 2017, In: Experimental Cell Research. 360, 1, p. 31-34 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
Agudelo, L. Z., Ferreira, D. M. S., Cervenka, I., Bryzgalova, G., Dadvar, S., Jannig, P. R., Pettersson-Klein, A. T., Lakshmikanth, T., Sustarsic, E. G., Porsmyr-Palmertz, M., Correia, J. C., Izadi, M., Martínez-Redondo, V., Ueland, P. M., Midttun, Ø., Gerhart-Hines, Zach, Brodin, P., Pereira, T., Berggren, P. & Ruas, J. L., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 378-392.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling
Khatib-Massalha, E., Bhattacharya, S., Massalha, H., Biram, A., Golan, K., Kollet, O., Kumari, A., Avemaria, F., Petrovich-Kopitman, E., Gur-Cohen, S., Itkin, T., Brandenburger, I., Spiegel, A., Shulman, Z., Gerhart-Hines, Z., Itzkovitz, S., Gunzer, M., Offermanns, S., Alon, R., Ariel, A. & 1 others, , 2020, In: Nature Communications. 11, 1, 18 p., 3547.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leveraging GPCR signaling in thermogenic fat to counteract metabolic diseases
Sveidahl Johansen, O., Ma, Tao & Gerhart-Hines, Zach, 2022, In: Molecular Metabolism. 60, 8 p., 101474.Research output: Contribution to journal › Review › Research › peer-review
- Published
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, , 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipolysis regulates major transcriptional programs in brown adipocytes
Markussen, L. K., Rondini, E. A., Johansen, O. S., Madsen, J. G. S., Sustarsic, E. G., Marcher, A. B., Hansen, Jacob B., Gerhart-Hines, Zach, Granneman, J. G. & Mandrup, S., 2022, In: Nature Communications. 13, 1, 16 p., 3956.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MCT1 helps brown fat suck up succinate
Lund, Jens, Isidor, Marie Sophie & Gerhart-Hines, Zach, 2024, In: Nature Metabolism. 6, p. 387–388Research output: Contribution to journal › Letter › Research › peer-review
- Published
Metabolic adaptations through the PGC-1α and SIRT1 pathways
Rodgers, J. T., Lerin, C., Gerhart-Hines, Zach & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice
Pendergrast, L. A., Ashcroft, Stephen Paul, Ehrlich, Amy M, Treebak, Jonas Thue, Krook, A., Dollet, L. & Zierath, Juleen R, 2024, In: Metabolism: Clinical and Experimental. 155, 12 p., 155834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis
Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner
Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
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A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
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NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
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Latest publications
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Research output: Contribution to journal › Journal article › Research › peer-review
Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M
Research output: Contribution to journal › Journal article › Research › peer-review
MCT1 helps brown fat suck up succinate
Research output: Contribution to journal › Letter › Research › peer-review