Publications acknowledging the platform
2026
Aalling NN, Todorov PV, Hassan S, et al. Sustained diabetes remission induced by FGF1 involves a shift in transcriptionally distinct AgRP neuron subpopulations. Mol Metab. 2026;103(102300):102300. doi:10.1016/j.molmet.2025.102300
Muñoz F, Gao Q, Mattanovich M, et al. Lysine potentiates insulin secretion via AASS-dependent catabolism and regulation of GABA content and signaling. Metabolism. 2026;174(156423):156423. doi:10.1016/j.metabol.2025.156423
Biswas D, Espino-Gonzalez E, Ahwazi D, et al. Common and distinct roles of AMPKγ isoforms in small-molecule activator-stimulated glucose uptake in mouse skeletal muscle. Mol Metab. 2026;103(102294):102294. doi:10.1016/j.molmet.2025.102294
Rausch DM, Ludwig MQ, Bentsen MA, et al. Semaglutide Attenuates Neuroinflammation in Mice. bioRxiv. Published online 12 January 2026. doi:10.64898/2026.01.10.698763
Negoita F, Fraguas Bringas C, Hellberg K, et al. AMPK promotes TFEB transcriptional activity through dephosphorylation at both MTORC1-dependent and -independent sites. Autophagy. Published online 23 February 2026:1-15. doi:10.1080/15548627.2026.2629720
Grothen JER, Martinez JM, Sidiropoulos N, et al. Single cell transcriptomics of human weight loss links adipocyte NPY1R to control of lipolysis. Mol Metab. 2026;105(102305):102305. doi:10.1016/j.molmet.2025.102305
2025
Tuulari JJ, et al. Exposure to childhood maltreatment is associated with specific epigenetic patterns in sperm. Mol Psychiatry. 2025;30(6):2635-2644. doi:10.1038/s41380-024-02872-3
Madsen S, et al. Rapid downregulation of DICER is a hallmark of adipose tissue upon high-fat diet feeding. Mol Cell Endocrinol. 2025;595:112413. doi:10.1016/j.mce.2024.112413
Agueda-Oyarzabal M, et al. Transcriptomic signatures of cold acclimated adipocytes reveal CXCL12 as a Brown autocrine and paracrine chemokine. Mol Metab. 2025;93(102102):102102. doi:10.1016/j.molmet.2025.102102
Ni D, et al. High fat low carbohydrate diet is linked to CNS autoimmunity protection. Adv Sci (Weinh). 2025;12(22):e2412236. doi:10.1002/advs.202412236
Gil CRE, et al. Food insecurity promotes adiposity in mice. Obesity (Silver Spring). 2025;33(6):1087-1100. doi:10.1002/oby.24259
Huang C, et al. Male obesity causes adipose mitochondrial dysfunction in F1progeny via a let-7-DICER axis. bioRxiv. Published online 2024. doi:10.1101/2024.10.03.615866
Ehrlich AM, et al. HIF1α mediates circadian regulation of skeletal muscle metabolism and substrate preference in response to time-of-day exercise. Proc Natl Acad Sci U S A. 2025;122(28):e2504080122. doi:10.1073/pnas.2504080122
Chubanava S, et al. NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging. Cell Metab. 2025;37(7):1460-1481.e17. doi:10.1016/j.cmet.2025.04.002
Fraguas Bringas C, et al. Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827. Sci Adv. 2025;11(34):eadx2434. doi:10.1126/sciadv.adx2434
Biswas D, et al. Common and distinct roles of AMPKγ isoforms in small-molecule activator-stimulated glucose uptake in mouse skeletal muscle. bioRxiv. Published online 2025. doi:10.1101/2025.09.26.678768
Dall M, et al. Hepatocyte dedifferentiation in 2D culture reveals extensive transcriptomic and proteomic rewiring. Hepatol Commun. 2025;9(11):e0795. doi:10.1097/HC9.0000000000000795
Juozaityte V, et al. The NMDA receptor antagonist memantine modulates aging and stress resilience. Aging Cell. 2026;25(1):e70303. doi:10.1111/acel.70303
Dollet L, et al. Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M. Cell Reports Medicine. 2024 Jan;5(1):101348. doi:10.1016/j.xcrm.2023.101348
Todorov PV, et al. An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity. Sci Data. 2024 Jan 6;11(1):44. doi: 10.1038/s41597-023-02888-4.
Farris KM, et al. Dietary macronutrient composition impacts gene regulation in adipose tissue. Commun Biol. 2024 Feb 16;7(1). doi:10.1038/s42003-024-05876-5
Lund C, et al. Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R. Nat Commun. 2024 Feb 8;15(1). doi:10.1038/s41467-024-45223-0
Fadahunsi N, et al. Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment. Sci Adv. 2024 Mar;10(9). doi:10.1126/sciadv.adg2636
Petersen J, et al. GLP-1-directed NMDA receptor antagonism for obesity treatment. Nature. 2024 May 15;629(8014):1133–41. doi:10.1038/s41586-024-07419-8
Carper D, et al. Loss of atrial natriuretic peptide signaling causes insulin resistance, mitochondrial dysfunction, and low endurance capacity. Sci Adv. 2024 Oct 11;10(41). doi:10.1126/sciadv.adl4374
2023
Lee J, et al. A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development. Sci Adv. 2023 Apr 7;9(14):eadd5745. doi: 10.1126/sciadv.add5745. Epub 2023 Apr 7.
Peluso AA, et al. Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans. NPJ Aging. 2023 Apr 3;9(1):7. doi: 10.1038/s41514-023-00106-4.
Basse AL, et al. NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2220102120. doi: 10.1073/pnas.2220102120. Epub 2023 Mar 30.
Falk S, et al. GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity. Cell Rep. 2023 May 30;42(5):112466. doi: 10.1016/j.celrep.2023.112466. Epub 2023 May 5.
Palani NP, et al. Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots. Nat Metab. 2023 Jun;5(6):996-1013. doi: 10.1038/s42255-023-00820-z. Epub 2023 Jun 19.
Urizar AI, et al. Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding. Cell Death Dis. 2023 Jul 5;14(7):399. doi: 10.1038/s41419-023-05906-w.
Lemcke R, et al. Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus. Elife. 2023 Sep 12;12:RP87515. doi: 10.7554/eLife.87515.
Small L, et al. Seasonal light hours modulate peripheral clocks and energy metabolism in mice. Cell Metab. 2023 Oct 3;35(10):1722-1735.e5. doi: 10.1016/j.cmet.2023.08.005. Epub 2023 Sep 8.
Pedersen SS, et al. Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction. FEBS J. 2023 Nov 20. doi: 10.1111/febs.17005. Epub ahead of print.
Dollet L, et al. Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M. Cell Rep Med. 2023 Dec 21:101348. doi: 10.1016/j.xcrm.2023.101348. Epub ahead of print.
2022
Moharrek F, et al. Comparative analysis of sperm DNA methylation supports evolutionary acquired epigenetic plasticity for organ speciation. Epigenomics. 2022 Nov;14(21):1305-1324. doi: 10.2217/epi-2022-0168. Epub 2022 Nov 24.
Fadahunsi N, et al. Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice. Transl Psychiatry. 2022 Aug 11;12(1):330. doi: 10.1038/s41398-022-02103-9.
Fred RG, et al. Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis. Sci Rep. 2022 Aug 5;12(1):13484. doi: 10.1038/s41598-022-16754-7.
McIlvenna LC, et al. Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome. J Physiol. 2022 Jul;600(14):3313-3330. doi: 10.1113/JP282954. Epub 2022 Jun 27.
Ferraz-Bannitz R, et al. Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome in a Randomized, Controlled Trial. Nutrients. 2022 Jun 28;14(13):2670. doi: 10.3390/nu14132670.
Andersen, E. et al. Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial. Hum Reprod. 2022 May 17. doi: 10.1093/humrep/deac096.
Andreassen CH, et al. RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma. Br J Cancer. 2022 Apr 13. doi: 10.1038/s41416-022-01810-w. Epub ahead of print.
Mads V, et al. Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity. iScience. 2022 Feb 18;25(2):103863. doi: 10.1016/j.isci.2022.103863.
2021
Dall M, et al. Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. J Biol Chem. 2021 Dec;297(6):101388. doi: 10.1016/j.jbc.2021.101388. Epub 2021 Nov 8.
Moreno-Asso A, et al. Non-cell autonomous mechanisms control mitochondrial gene dysregulation in polycystic ovary syndrome. J Mol Endocrinol. 2021 Dec 3;68(1):63-76. doi: 10.1530/JME-21-0212.
Gabriel BM, et al. Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle. Sci Adv. 2021 Oct 22;7(43):eabi9654. doi: 10.1126/sciadv.abi9654. Epub 2021 Oct 20.
Grunddal KV, et al. Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells. Mol Metab. 2021 Sep;51:101231. doi: 10.1016/j.molmet.2021.101231.
Brown JM, et al. Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission. iScience. 2021 Aug 4;24(9):102944. doi: 10.1016/j.isci.2021.102944.
Altıntaş A, et al. Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action. FASEB J. 2021 Jul;35(7):e21702. doi: 10.1096/fj.202100215R.
Williams K, et al. Epigenetic rewiring of skeletal muscle enhancers after exercise training supports a role in whole-body function and human health. Mol Metab. 2021 Jul 10;53:101290. doi: 10.1016/j.molmet.2021.101290.
Basse AL, et al. Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity. Mol Metab. 2021 Jun 11;53:101271. doi: 10.1016/j.molmet.2021.101271.
Ludwig MQ et al. A genetic map of the mouse dorsal vagal complex and its role in obesity. Nature Metabolism. 2021 Mar 25. doi: 10.1038/s42255-021-00363-1.
Hundahl C et al. Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis. Molecular Metabolism. 2021 Feb 5;47:101174. doi: 10.1016/j.molmet.2021.101174.
Small L, et al. Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity. PLoS Genet. 2021 Jan 29;17(1):e1009325. doi: 10.1371/journal.pgen.1009325.
2020
Ardenkjær-Larsen J, et al. Insulin-induced serine 22 phosphorylation of retinoid X receptor alpha is dispensable for adipogenesis in brown adipocytes. Adipocyte. 2020 Dec; 9(1):142-152. doi: 10.1080/21623945.2020.1747352.
Pfisterer U et al. Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis. Nature Communications. 2020 Oct 7;11(1):5038. doi: 10.1038/s41467-020-18752-7. Erratum in: Nat Commun. 2020 Nov 19;11(1):5988.
Nicolaisen TS et al. Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure. FASEB Journal. 2020 Nov;34(11):15480-15491. doi: 10.1096/fj.202001258RR. Epub 2020 Sep 23.
Timshel PN et al. Genetic mapping of etiologic brain cell types for obesity. Elife. 2020 Sep 21;9:e55851. doi: 10.7554/eLife.55851.
Lundell LS et al. Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression. Nature Communications. 2020 Sep 16;11(1):4643. doi: 10.1038/s41467-020-18412-w.
Bentsen MA et al. Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission. Nature Communications. 2020 Sep 7;11(1):4458. doi: 10.1038/s41467-020-17720-5.
Rifes P et al. Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. Nature Biotechnology. 2020 Nov;38(11):1265-1273. doi: 10.1038/s41587-020-0525-0. Epub 2020 May 25. Erratum in: Nature Biotechnology. 2020 Jun 11.
Williams K et al. Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism. Nat Communications. 2020 Jun 1;11(1):2695. doi: 10.1038/s41467-020-16537-6.
2019
Linscheid N, et al. Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking. Nat Commun. 2019 Jun 28;10(1):2889. doi: 10.1038/s41467-019-10709-9.
Skov LJ, et al. RhoA in tyrosine hydroxylase neurones regulates food intake and body weight via altered sensitivity to peripheral hormones. J Neuroendocrinol. 2019 Jul;31(7):e12761. doi: 10.1111/jne.12761.