Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine

    Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In: Molecular Endocrinology. 140, 11, p. 5356-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor

    Hansen, L. S., wbf943, wbf943, Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 826-838 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Somastostatin restrains the secretion of glucagon-like peptide-1 and 2 (GLP-1 and GLP-2) from isolated perfused porcine ileum

    Hansen, L., Hartmann, B., Bisgaard, T., Mineo, H., Jørgensen, P. N. & Holst, Jens Juul, 2000, In: Am. J. Physiol.. 278, p. E1010-E1018

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells

    Hansen, L., Deacon, Carolyn F., Ørskov, C. & Holst, Jens Juul, 1999, In: Endokrinologiya. 140, p. 5356-5363

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glucagon-like peptide- 1 secretion is influenced by perfusate glucose concentration and a feedback mechanism involving somatostatin in isolated perfused porcine ileum

    Hansen, L., Hartmann, B., Mineo, H. & Holst, Jens Juul, 2004, In: Regul. Pept.. 118, p. 11-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Neural regulation of glucagon-like peptide- 1 secretion in pigs

    Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, 2004, In: Am. J. Physiol.. 287, p. E939-E947

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists

    Hansen, L. S., wbf943, wbf943, Svendsen, B., Christensen, M., Hartmann, Bolette, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Sep 2015, In: Diabetologia. 58, 1 supplement, p. S276-S277 2 p., 569.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  8. Published

    Acute effects of glucagon-like peptide-1, GLP-19-36 amide, and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers

    Hansen, Lasse Bremholm, Andersen, U. B., Hornum, Mads, Hilsted, L., Veedfald, S., Hartmann, Bolette & Holst, Jens Juul, Feb 2017, In: Physiological Reports. 5, 4, 12 p., e13102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

    Hansen, L. B. S., Roager, H. M., Søndertoft, N. B., Gøbel, R. J., Kristensen, M. B., Vallès-Colomer, M., Vieira-Silva, S., Ibrügger, S., Lind, M. V., Mærkedahl, R. B., Bahl, M. I., Madsen, M. L., Havelund, J., Falony, G., Tetens, I., Nielsen, T., Allin, K. H., Frandsen, H. L., Hartmann, B., Holst, J. J. & 32 others, Sparholt, M. H., Holck, J., Blennow, Andreas, Moll, J. M., Meyer, A. S., Hoppe, C., Poulsen, J. H., Carvalho, V., Sagnelli, D., Dalgaard, M. D., Christensen, A. F., Lydolph, M., Ross, A. B., Villas-Bôas, S. G., Brix, S., Sicheritz-Pontén, T., Buschard, K., Linneberg, Allan René, Rumessen, J. J., Ekstrøm, Claus Thorn, Ritz, C., Kristiansen, Karsten, Nielsen, H. B., drb459, drb459, Færgeman, N. J., Raes, J., Frøkiær, Hanne, Hansen, Torben, Lauritzen, Lotte, Gupta, R., Licht, T. R. & Pedersen, Oluf Borbye, 2018, In: Nature Communications. 9, 13 p., 4630.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Neural regulation of glucagon-like peptide-1 secretion in pigs

    Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, Nov 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 5, p. E939-47

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.

    Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop?

    Hansen, L. & Holst, Jens Juul, 31 Dec 2002, In: Regulatory Peptides. 110, 1, p. 39-45 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum

    Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 11-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Important species differences regarding lymph contribution to gut hormone responses

    Hansen, M., Hjøllund, K. R., Hartmann, Bolette, Plamboeck, A., Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 28-31 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4

    Hansen, M., Knop, Filip Krag & Holst, Jens Juul, Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors

    Hansen, M., Juul Hare, K., Holst, Jens Juul & Knop, Filip Krag, Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion

    Hansen, M., Scheltema, M. J., Sonne, David Peick, Hansen, J. S., Sperling, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jun 2016, In: Diabetes, Obesity and Metabolism. 18, 6, p. 571-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Glucagon-Like Peptide 2 Inhibits Postprandial Gallbladder Emptying in Man: A Randomized, Double-Blinded, Crossover Study

    Hansen, N. L., Brønden, Andreas, Nexoe-Larsen, C. C., Christensen, A. S., Sonne, D. P., Rehfeld, Jens Frederik, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2020, In: Clinical and Translational Gastroenterology. 11, 12, 9 p., e00257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Novel Mody3 Mutations in the Hepatocyte Factor-1a Gene. Evidence for a Hyperexcitabillity of Pancreatic ß-cells to Intravenous Secretagogues in a Glucosetolerant Carrier of a P447L Mutation

    Hansen, T., Eiberg, Hans Rudolf Lytchoff, Rouard, M., Vaxillaire, M., Møller, A. M., Rasmussen, S. K., Fridberg, M. & Holst, Jens Juul, 1997, In: Diabetes. 46, p. 726-730

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors

    Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., 2004, In: Diabetes. 53, p. 1326-1335

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors

    Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., May 2004, In: Diabetes. 53, 5, p. 1326-35 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes

    Harder-Lauridsen, N. M., Krogh-Madsen, Rikke, Holst, Jens Juul, Plomgaard, P., Leick, L., Pedersen, Bente Klarlund & Fischer, C. P., 1 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 7, p. E769-78 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

    Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes

    Hare, K. J., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 1 Apr 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 4, p. E832-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

    Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.

    Hare, K. J., Hartmann, B., Kissow, Hannelouise, Holst, Jens Juul & Poulsen, Steen Seier, 2007, In: Clinical Cancer Research. 13, 17, p. 5170-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Galanin and vasoactive intestinal polypeptide: coexistence and corelease from the vascularly perfused pig ileum during distension and chemical stimulation of the mucosa

    Harling, H., Messell, T., Poulsen, Steen Seier & Holst, Jens Juul, 1991, In: Digestion. 50, 2, p. 61-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Galanin: Distribution and Effect on Contractile Activity and Release of Vasoactive Intestinal Polypeptide from the Isolated Perfused Porcine Ileum

    Harling, H., Gregersen, H., Rasmussen, T. N., Holst, Jens Juul & Poulsen, S. S., 1990, In: Digestion. 47, p. 191-199

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Circulating galanin: origin, metabolism, and pharmacokinetics in anesthetized pigs

    Harling, H. & Holst, Jens Juul, 1992, In: Am. J. of Physiology. 262, p. E52-E57

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Galanin and vasoactive intestinal polypeptide: Release during intraluminal, chemical irritation and distension of the isolated perfused porcine ileum

    Harling, M., Messel, T., Holst, Jens Juul & Poulsen, S. S., 1991, In: Digestion. 50, p. 61-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity

    Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  32. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    In vivo and in vitro degradation of glucagon-like peptide-2 in humans

    Hartmann, B., Harr, M. B., Jeppesen, P. B., Wojdemann, M., Deacon, Carolyn F., Mortensen, P. B. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 2884-2888

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Immunoneutralization of endogenous glucagon-like peptide-2 reduces adaptive intestinal growth in diabetic rats.

    Hartmann, B., Thulesen, J., Hare, K. J., Kissow, Hannelouise, Orskov, C., Poulsen, Steen Seier & Holst, Jens Juul, 2002, In: Regulatory Peptides. 105, 3, p. 173-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes

    Hartmann, Bolette, Longo, M., Mathiesen, D. S., Hare, Kristine Juul, Jørgensen, Niklas Rye, Esposito, K., Deacon, Carolyn F., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. e259-e265 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study

    Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study

    Hartvigsen, M. L., Gregersen, S., Lærke, H. N., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., Jan 2014, In: European Journal of Clinical Nutrition. 68, 1, p. 84-90 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor

    Hassing, H. A., Engelstoft, M. S., Sichlau, R. M., Madsen, A. N., Rehfeld, Jens Frederik, Pedersen, Jens, Jones, R. M., Holst, Jens Juul, Schwartz, Thue W., Rosenkilde, Mette & Hansen, Harald S., 2016, In: BioFactors. 42, 6, p. 665-673

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells

    Haugaard, Steen Bendix, Andersen, Ove, Dela, Flemming, Holst, Jens Juul, Storgaard, H., Fenger, M., Iversen, J. & Madsbad, Sten, Jan 2005, In: European Journal of Endocrinology. Supplement. 152, 1, p. 103-12 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.

    Haugaard, S. B., Andersen, Ove, Dela, Flemming, Holst, Jens Juul, Storgaard, H., Fenger, M., Iversen, J., Madsbad, Sten, Haugaard, S. B., Andersen, Ove, Dela, F., Holst, J. J., Storgaard, H., Fenger, M., Iversen, J. & Madsbad, Sten, 2005, In: European Journal of Endocrinology. 152, 1, p. 103-112 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagons, lactate and TNF-alfa in patients with HIV-lipodystrophy

    Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J. & Madsbad, Sten, 2006, In: HIV Medicine. 7, p. 163-172 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.

    Haugaard, S. B., Andersen, Ove, Storgaard, H., Dela, Flemming, Holst, Jens Juul, Iversen, J., Nielsen, J. O. & Madsbad, Sten, 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 4, p. E677-85 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.

    He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In: Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.

    He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In: Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effect of meal texture on glucose excursions after bariatric surgery

    Hedbäck, N., Hindso, M., Linddal, A. K., Bojsen-Moller, K. N., Jorgensen, N. B., Dirksen, C., Moller, A., Kristiansen, V. B., Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2020, In: Diabetologia. 63, Suppl. 1, p. S203 1 p., 411.

    Research output: Contribution to journalConference abstract in journalResearch

  46. Published

    Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

    Hedbäck, N., Hindsø, M., Bojsen-Møller, K. N., Linddal, A. K., Jørgensen, N. B., Dirksen, C., Møller, A., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Svane, M. S. & Madsbad, Sten, 2022, In: Frontiers in Nutrition. 9, 889710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effect of glucagon-like peptide 1 (7-356) amide in insulin treated patients with diabetes mellitus secondary to chronic pancreatitis

    Hedetoft, C., Larsen, S., Sheikh, S. & Holst, Jens Juul, 2000, In: Pancreas. 20, p. 25-31

    Research output: Contribution to journalJournal articleResearch

  48. Published

    Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes

    Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.

    Research output: Contribution to journalConference abstract in journalResearch

  49. Published

    Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes

    Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial

    Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Effect of glucagon immunoneutralization on the increase in urea synthesis after hysterectomy in rats

    Heindorff, H., Holst, Jens Juul, Almdal, T. P. & Vilstrup, H., 1993, In: European Journal of Clinical Investigation. 23, p. 166-170

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    The effect of curcumin on hepatic fat content in individuals with obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellstrom, P. M., Naslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., 2008, In: Neurogastroenterology and Motility. 20, 6, p. 649-659 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellström, P. M., Näslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., Jun 2008, In: Neurogastroenterology and Motility Online. 20, 6, p. 649-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The role of the incretins in the postprandial bone remodelling

    Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  59. Published

    The role of endogenous GIP and GLP-1 in postprandial bone homeostasis

    Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Disassociation of bone resorption and formation by GLP-2 - A 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, B., Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2007, In: Bone. 40, 3, p. 723-729 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.

    Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In: Bone. 45, 5, p. 833-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Role of gastrointestinal hormones in postprandial reduction of bone resorption

    Henriksen, D. B., Alexandersen, P., Bjarnason, N. H., Vilsbøll, Tina, Hartmann, B., Henriksen, E. E. G., Byrjalsen, I., Krarup, T., Holst, Jens Juul & Christiansen, C., 1 Dec 2003, In: J Bone Miner Res. 18, 12, p. 2180-2190 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Glucose mediated glucose disposal in insulin resistant normoglycemic relatives of type 2 diabetic patients

    Henriksen, J. E., Levin, K., Thye-Rønn, P., Alford, F., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2000, In: Diabetes. 49, p. 1209-1218

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Elevated circulating leptin in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin

    Henriksen, J. H., Holst, Jens Juul, Møller, S., Jensen, G. & Bendtsen, Flemming, 2000, In: Clin.Sci.. 99, p. 527-534

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Increased Circulating leptin in cirrhosis: relation to release and disposal

    Henriksen, J. H., Holst, Jens Juul, Møller, S., Brinch, K. & Bendtsen, Flemming, 1999, In: Hepatology. 29, p. 1818-1824

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Elevated ciculating leptin levels in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin

    Henriksen, J. H., Holst, Jens Juul & Moller, S., 2001, In: Clin.Sci.. 99, p. 527-534

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes

    Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.

    Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q. & 7 others, Zeng, W., Davies, M. J., Tanaka, W., Holst, Jens Juul, Deacon, Carolyn F., Gottesdiener, K. M. & Wagner, J. A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Postprandial Dyslipidemia, Hyperinsulinemia, and Impaired Gut Peptides/Bile Acids in Adolescents with Obesity

    Higgins, V., Asgari, S., Hamilton, J. K., Wolska, A., Remaley, A. T., Hartmann, Bolette, Holst, Jens Juul & Adeli, K., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. 1228-1241

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Effects of topical ropivacaine on eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis

    Hillingsø, Jens Georg, Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Fisher-Hansen, B., Holst, Jens Juul, Lauristen, K., Bukhave, K. & Rask-Madsen, J., Mar 2002, In: Scandinavian Journal of Gastroenterology. 37, 3, p. 325-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Preservation of active Effects of topical ropivacaine om eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis

    Hillingsøe, J. G., Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Arlander, E., Fischer-Hansen, B., Holst, Jens Juul, Lauritsen, K., Bukhave, K. & Rask-Madsen, J., 2002, In: Scandinavian Journal of Gastroenterology. 37, p. 325-329

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Plasma glucagon and glucose recovery after hypoglycemia: The effect of total autonomic blockade

    Hilsted, J., Frandsen, H., Holst, Jens Juul, Christensen, J. & Nielsen, S. L., 1991, In: Acta Endocrinol.. 125, p. 466-469

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Importance of endogenous GLP-1 and GIP for postprandial glucose tolerance after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindso, M., Hedback, N., Moller, A., Svane, M. S., Martinussen, C., Jorgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 200-201 387.

    Research output: Contribution to journalConference abstract in journalResearch

  76. Published

    Effect of 6 weeks of very low-volume high-intensity interval training on oral glucose-stimulated incretin hormone response

    Hindsø, M., Kuhlman, A. B., Dohlmann, T. L., Lund, M. T., Hartmann, Bolette, Holst, Jens Juul, Larsen, Steen & Helge, Jørn Wulff, 2022, In: European Journal of Sport Science. 22, 3, p. 381-389

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies

    Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391

    Research output: Contribution to journalReviewResearchpeer-review

  79. Published

    Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance

    Hindsø, M., Bojsen-Møller, K. N., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, 2022, In: International Journal of Obesity. 46, 7, p. 1359-1365

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Delayed ß-cell response and glucose intolerance in young women with Turner syndrome

    Hjerrild, B. E., Holst, Jens Juul, Juhl, C., Christiansen, J. S., Schmitz, O. & Gravholt, C. H., 2011, In: B M C Endocrine Disorders. 11, p. 11-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs

    Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  82. Published

    The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion

    Hjørne, A. P., Modvig, Ida Marie & Holst, Jens Juul, 2022, In: Metabolites. 12, 5, 15 p., 420.

    Research output: Contribution to journalReviewResearchpeer-review

  83. Published

    Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects

    Hlebowicz, J., Hlebowicz, A., Lindstedt, S., Björgell, O., Höglund, P., Holst, Jens Juul, Darwiche, G. & Almér, L., 2009, In: American Journal of Clinical Nutrition. 89, 3, p. 815-21 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    GIP infusion in patients with type 1 diabetes seems to attenuate post-prandial glucose excursions after prandial insulin over-dose and physical activity

    Hoe, B., Heimburger, S. M. N., Gasbjerg, L. S., Lanng, A. R., Lynggaard, M. B., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A., Engberg, S., Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, Suppl. 1, p. S117 1 p., 232.

    Research output: Contribution to journalConference abstract in journalResearch

  85. Published
  86. Published

    Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels

    Hofsø, D., Birkeland, K. I., Holst, Jens Juul, Bollerslev, J., Sandbu, R., Røislien, J. & Hjelmesæth, J., 2015, In: Diabetology & Metabolic Syndrome. 7, p. 1-4 4 p., 69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    A single supplement of a standardised bilberry (Vaccinium myrtillus L.) extract (36 % wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes controlled by diet and lifestyle

    Hoggard, N., Cruickshank, M., Moar, K., Bestwick, C., Holst, Jens Juul, Russell, W. & Horgan, G., 2013, In: Journal of Nutritional Science. 2, 9 p., e22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting

    Hojlund, K., Wildner-Christensen, M., Eshoj, O. & Holst, Jens Juul, 2001, In: Am J Physiol-Endoc M. 280, p. E50-E58

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Effect of chemical myenteric ablation on the structure proliferation and endocrine cells in the small intestinal mucosa

    Holle, G. E., Demir, I., Dietl, J., Rehfeld, J. F. & Holst, Jens Juul, 1992, Advances in the Innervation of the Gastrointestinal Tract. Aspen Publishers

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  90. Published

    Effect of chemical myenteric ablation on the structure, proliferation and endocrine cells in the small intestinal mucosa

    Holle, G. E., Demir, I., Dietl, J., Forssmann, W. G., Rehfeld, J. F. & Holst, Jens Juul, 1993, In: Advances in the Innervation of the Gastrointestinal Tract. p. 89-98

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.

    Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects

    Holmer-Jensen, J., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2013, In: Nutrition Research. 33, 1, p. 34-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects

    Holmer-Jensen, J., Hartvigsen, M., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, p. 32-38 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

    Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    On the effects of human galanin in man

    Holst, Jens Juul, Bersani, M., Hvidberg, A., Knigge, Ulrich, Christiansen, E. M., Madsbad, Sten, Harling, H. & Kofod, H., 1993, In: Diabetologia. 36, 7, p. 653-657 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin-releasing peptide, and HCl from porcine non-antral stomach

    Holst, Jens Juul, Skak-Nielsen, T., Ørskov, Cathrine & Seier-Poulsen, S., Aug 1992, In: Scandinavian Journal of Gastroenterology. 27, 8, p. 677-85 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    GRP nerves in pig antrum: role of GRP in vagal control of gastrin secretion

    Holst, Jens Juul & Poulsen, Steen Seier, Nov 1987, In: American Journal of Physiology (Consolidated). 253, 5 Pt 1, p. G643-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    GRP-producing nerves control antral somatostatin and gastrin secretion in pigs

    Holst, Jens Juul, Ørskov, Cathrine & Poulsen, Steen Seier, Dec 1987, In: American Journal of Physiology (Consolidated). 253, 6 Pt 1, p. G767-74

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    On the regulatory functions of neuropeptide Y (NPY) with respect to vascular resistance and exocrine and endocrine secretion in the pig pancreas

    Holst, Jens Juul, Ørskov, Cathrine, Knuhtsen, S., Sheikh, S. & Nielsen, O. V., Aug 1989, In: Acta Physiologica Scandinavica. 136, 4, p. 519-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Occurrence, distribution and motor effects of galanin in the porcine lower esophageal sphincter

    Holst, Jens Juul & Poulsen, Steen Seier, 1989, In: Digestion. 42, 3, p. 151-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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