Thue W. Schwartz
Professor
Schwartz Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
- 1998
- Published
Differential regulation of CXCR4 and CCR5 endocytosis
Signoret, N., Rosenkilde, Mette, Klasse, P. J., Schwartz, Thue W., Malim, M. H., Hoxie, J. A. & Marsh, M., 1998, In: Journal of Cell Science. 111, no. 18, p. 2819-2830Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational evidence for a common kappa antagonist binding pocket in the wild-type kappa and mutant mu[K303E] opioid receptors
Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 1998, In: Journal of Medicinal Chemistry. 41, p. 4911-4914Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor
Rosenkilde, Mette, Lucibello, M., Holst, Birgitte & Schwartz, Thue W., 1998, In: FEBS Letters. 439, 1-2, p. 35-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles of Agonism - Undressing Efficacy
Schwartz, Thue W. & Ijzermann, A. P., 1998, In: TIPS - Trends in Pharmacological Sciences. 19, no. 11, p. 433-436Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28
Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Split-receptors in the tachykinin NK-1 system - mutational analysis of intracellular loop 3
Nielsen, S. M., Elling, C. E. & Schwartz, Thue W., 1998, In: European Journal of Biochemistry. 251, p. 217-226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor
Holst, Birgitte, Jensen, S. Z., Elling, C. E., Hjorth, S. A. & Schwartz, Thue W., 1998, In: Molecular Pharmacology. 53, no. 1, p. 166-175Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CCR5 receptor acts as an alloantigen in CCR5¿32 homozygous individuals: Identification of chemokine- and HIV-1 blocking human antibodies
Ditzel, H. J., Rosenkilde, Mette, Garred, P., Wang, M., Pedersen, C., Burton, D. R. & Schwartz, Thue W., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, no. 9, p. 5241-5245Research output: Contribution to journal › Journal article › Research › peer-review
- Published
XVI: International Union of Pharmacology Recommendations for the nomenclature of neuropeptide Y, peptide YY and pancreatic polypeptide receptors
Michel, M. C., Beck-Sickinger, A., Cox, H., Doods, H. N., Herzog, H., Larhammer, D., Quirion, R., Schwartz, Thue W. & Westfall, T., 1998, In: Pharmacological Reviews. 50, no. 1, p. 143-150Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
CD4-chemokine receptor hybrids in human immunodeficiency virus type 1 infection
Klasse, P. J., Rosenkilde, Mette, Signoret, N., Pelchen-Matthews, A., Schwartz, Thue W. & Marsh, M., 1999, In: Journal of Virology. 73, no. 9, p. 7453-7466Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor
Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 22, p. 12322-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conversion of agonist site to metal-ion chelator site in the ¿2-adrenergic receptor
Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, no. 22, p. 12322-12327Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74
Rosenkilde, Mette, Kledal, T. N., Bräuner, Hans & Schwartz, Thue W., 8 Jan 1999, In: Journal of Biological Chemistry. 274, 2, p. 956-961Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum
Lüttichau, H. R., J., S., Boesen, T. P., Johnsen, A. H., Chantry, D., Gerstoft, J. & Schwartz, Thue W., 2000, In: Journal of Experimental Medicine. 191, no. 1, p. 171-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of norbinaltorphimine (norBNI) congeners to wild-type and mutant mu and kappa opioid receptors: molecular recognition loci for the pharmacophore and address components of kappa antagonists
Larson, D. L., Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 2000, In: Journal of Medicinal Chemistry. 43, no. 8, p. 1573-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disulfide bridge engineering in the tachykinen NK1 receptor
Elling, C. E., Raffetseder, U., Nielsen, S. M. & Schwartz, Thue W., 2000, In: Biochemistry. 39, no. 4, p. 667-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor
Costa-Neto, C. M., Miyakawa, A. A., Oliveira, L., Hjorth, S. A., Schwartz, Thue W. & Paiva, A. C., 2000, In: British Journal of Pharmacology. 130, no. 6, p. 1263-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor
Holst, Birgitte, Elling, C. E. & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 58, 2, p. 263-70 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor
Rosenkilde, Mette & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 57, no. 3, p. 602-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74
Rosenkilde, Mette, Kledal, T. N., Holst, Peter Johannes & Schwartz, Thue W., 2000, In: Journal of Biological Chemistry. 275, 34, p. 26309-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of chemokine receptors as drug targets
Lüttichau, H. R. & Schwartz, Thue W., 2000, In: Current Opinion in Drug Discovery & Development. 3, no. 5, p. 610-623Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Enhanced fluorescence resonance energy transfer between spectral variants of green fluorescent protein through zinc-site engineering
Jensen, K. K., Martini, L. & Schwartz, Thue W., 2001, In: Biochemistry. 40 (4), p. 938-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MC148 encoded by human molluscum contagiosum poxvirus is an antagonist for human but not murine CCR8
Lüttichau, H. R., Gerstoft, Jan & Schwartz, Thue W., 2001, In: Journal of Leukocyte Biology. 70, 2, p. 277-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine
Mizoue, L. S., Sullivan, S. K., King, D. S., Kledal, T. N., Schwartz, Thue W., Bacon, K. B. & Handel, T. M., 2001, In: Journal of Biological Chemistry. 276, 36, p. 33906-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor
Gerlach, L., Skerlj, R. T., Bridger, G. J. & Schwartz, Thue W., 2001, In: Journal of Biological Chemistry. 276 (17), p. 14153-14160Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11601
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
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2786
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
609
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Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Research output: Contribution to journal › Journal article › Research › peer-review
Published