Thue W. Schwartz

Thue W. Schwartz

Professor

Member of:


    1. 1998
    2. Published

      Differential regulation of CXCR4 and CCR5 endocytosis

      Signoret, N., Rosenkilde, Mette, Klasse, P. J., Schwartz, Thue W., Malim, M. H., Hoxie, J. A. & Marsh, M., 1998, In: Journal of Cell Science. 111, no. 18, p. 2819-2830

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Mutational evidence for a common kappa antagonist binding pocket in the wild-type kappa and mutant mu[K303E] opioid receptors

      Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 1998, In: Journal of Medicinal Chemistry. 41, p. 4911-4914

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor

      Rosenkilde, Mette, Lucibello, M., Holst, Birgitte & Schwartz, Thue W., 1998, In: FEBS Letters. 439, 1-2, p. 35-40 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Principles of Agonism - Undressing Efficacy

      Schwartz, Thue W. & Ijzermann, A. P., 1998, In: TIPS - Trends in Pharmacological Sciences. 19, no. 11, p. 433-436

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28

      Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Split-receptors in the tachykinin NK-1 system - mutational analysis of intracellular loop 3

      Nielsen, S. M., Elling, C. E. & Schwartz, Thue W., 1998, In: European Journal of Biochemistry. 251, p. 217-226

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor

      Holst, Birgitte, Jensen, S. Z., Elling, C. E., Hjorth, S. A. & Schwartz, Thue W., 1998, In: Molecular Pharmacology. 53, no. 1, p. 166-175

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      The CCR5 receptor acts as an alloantigen in CCR5¿32 homozygous individuals: Identification of chemokine- and HIV-1 blocking human antibodies

      Ditzel, H. J., Rosenkilde, Mette, Garred, P., Wang, M., Pedersen, C., Burton, D. R. & Schwartz, Thue W., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, no. 9, p. 5241-5245

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      XVI: International Union of Pharmacology Recommendations for the nomenclature of neuropeptide Y, peptide YY and pancreatic polypeptide receptors

      Michel, M. C., Beck-Sickinger, A., Cox, H., Doods, H. N., Herzog, H., Larhammer, D., Quirion, R., Schwartz, Thue W. & Westfall, T., 1998, In: Pharmacological Reviews. 50, no. 1, p. 143-150

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. 1999
    12. Published

      CD4-chemokine receptor hybrids in human immunodeficiency virus type 1 infection

      Klasse, P. J., Rosenkilde, Mette, Signoret, N., Pelchen-Matthews, A., Schwartz, Thue W. & Marsh, M., 1999, In: Journal of Virology. 73, no. 9, p. 7453-7466

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor

      Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 22, p. 12322-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Conversion of agonist site to metal-ion chelator site in the ¿2-adrenergic receptor

      Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, no. 22, p. 12322-12327

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

      Rosenkilde, Mette, Kledal, T. N., Bräuner, Hans & Schwartz, Thue W., 8 Jan 1999, In: Journal of Biological Chemistry. 274, 2, p. 956-961

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. 2000
    17. Published

      A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum

      Lüttichau, H. R., J., S., Boesen, T. P., Johnsen, A. H., Chantry, D., Gerstoft, J. & Schwartz, Thue W., 2000, In: Journal of Experimental Medicine. 191, no. 1, p. 171-80

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Binding of norbinaltorphimine (norBNI) congeners to wild-type and mutant mu and kappa opioid receptors: molecular recognition loci for the pharmacophore and address components of kappa antagonists

      Larson, D. L., Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 2000, In: Journal of Medicinal Chemistry. 43, no. 8, p. 1573-6

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Disulfide bridge engineering in the tachykinen NK1 receptor

      Elling, C. E., Raffetseder, U., Nielsen, S. M. & Schwartz, Thue W., 2000, In: Biochemistry. 39, no. 4, p. 667-75

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor

      Costa-Neto, C. M., Miyakawa, A. A., Oliveira, L., Hjorth, S. A., Schwartz, Thue W. & Paiva, A. C., 2000, In: British Journal of Pharmacology. 130, no. 6, p. 1263-8

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor

      Holst, Birgitte, Elling, C. E. & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 58, 2, p. 263-70 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor

      Rosenkilde, Mette & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 57, no. 3, p. 602-9

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74

      Rosenkilde, Mette, Kledal, T. N., Holst, Peter Johannes & Schwartz, Thue W., 2000, In: Journal of Biological Chemistry. 275, 34, p. 26309-15 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Validation of chemokine receptors as drug targets

      Lüttichau, H. R. & Schwartz, Thue W., 2000, In: Current Opinion in Drug Discovery & Development. 3, no. 5, p. 610-623

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2001
    26. Published

      Enhanced fluorescence resonance energy transfer between spectral variants of green fluorescent protein through zinc-site engineering

      Jensen, K. K., Martini, L. & Schwartz, Thue W., 2001, In: Biochemistry. 40 (4), p. 938-945

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      MC148 encoded by human molluscum contagiosum poxvirus is an antagonist for human but not murine CCR8

      Lüttichau, H. R., Gerstoft, Jan & Schwartz, Thue W., 2001, In: Journal of Leukocyte Biology. 70, 2, p. 277-82 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine

      Mizoue, L. S., Sullivan, S. K., King, D. S., Kledal, T. N., Schwartz, Thue W., Bacon, K. B. & Handel, T. M., 2001, In: Journal of Biological Chemistry. 276, 36, p. 33906-14 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor

      Gerlach, L., Skerlj, R. T., Bridger, G. J. & Schwartz, Thue W., 2001, In: Journal of Biological Chemistry. 276 (17), p. 14153-14160

      Research output: Contribution to journalJournal articleResearchpeer-review

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