Thue W. Schwartz

Thue W. Schwartz

Professor

Member of:


    1. Published

      Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network

      Valentin-Hansen, L., Frimurer, Thomas Michael, Mokrosinski, J., Holliday, N. D. & Schwartz, Thue W., 2 Oct 2015, In: The Journal of Biological Chemistry. 290, 40, p. 24495-508 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119

      Hassing, H. A., Fares, S., Larsen, Olav, Pad, H., Pedersen, M. H., Jones, R. M., Schwartz, Thue W., Hansen, Harald S. & Rosenkilde, Mette, 26 Aug 2016, In: Biochemical Pharmacology. 119, 1, p. 66-75 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Bidirectional GPR119 agonism requires peptide YY and glucose for activity in mouse and human colon mucosa

      Tough, I. R., Forbes, S., Herzog, H., Jones, R. M., Schwartz, Thue W. & Cox, H. M., 1 Apr 2018, In: Endocrinology. 159, 4, p. 1704-1717

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Binding of norbinaltorphimine (norBNI) congeners to wild-type and mutant mu and kappa opioid receptors: molecular recognition loci for the pharmacophore and address components of kappa antagonists

      Larson, D. L., Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 2000, In: Journal of Medicinal Chemistry. 43, no. 8, p. 1573-6

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Bioorthogonal Labeling of Ghrelin Receptor to Facilitate Studies of Ligand-Dependent Conformational Dynamics

      Park, M., Sivertsen, B. B., Els-Heindl, S., Huber, T., Holst, Birgitte, Beck-Sickinger, A. G., Schwartz, Thue W. & Sakmar, T. P., 19 Nov 2015, In: Chemistry & Biology. 22, 11, p. 1431-1436 6 p.

      Research output: Contribution to journalLetterResearchpeer-review

    6. Published

      Bioorthogonal fluorescent labeling of functional G-protein-coupled receptors

      Tian, H., Naganathan, S., Kazmi, M. A., Schwartz, Thue W., Sakmar, T. P. & Huber, T., 18 Aug 2014, In: ChemBioChem. 15, 12, p. 1820-9 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      C-terminal KDEL-modified cystatin C is retained in transfected CHO cells

      Johansen, T. E., Vogel, Lotte & Schwartz, Thue W., 1990, In: Biochemical and Biophysical Research Communications. 172, 3, p. 1384-91 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor

      Casarosa, P., Waldhoer, M., LiWang, P. J., Vischer, H. F., Kledal, T., Timmerman, H., Schwartz, Thue W., Smit, M. J. & Leurs, R., 2005, In: Journal of Biological Chemistry. 280, 5, p. 3275-3285 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      CD4-chemokine receptor hybrids in human immunodeficiency virus type 1 infection

      Klasse, P. J., Rosenkilde, Mette, Signoret, N., Pelchen-Matthews, A., Schwartz, Thue W. & Marsh, M., 1999, In: Journal of Virology. 73, no. 9, p. 7453-7466

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle

      Abdelmoez, A. M., Dmytriyeva, O., Zurke, Y. X., Trauelsen, Mette, Marica, A. A., Savikj, M., Smith, J. A. B., Monaco, C., Schwartz, Thue W., Krook, A. & Pillon, N. J., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 324, 4, p. E289-E298 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Characterization of G-protein coupled receptor kinase interaction with the NK-1 receptor using BRET

      Joergensen, R., Holliday, N. D., Hansen, J. L., Vrecl, M., Heding, A., Elling, C. E. & Schwartz, Thue W., 2008, In: Molecular Pharmaceutics. 73, 2, p. 349-358 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

      Jorgensen, R., Holliday, N. D., Hansen, J. L., Vrecl, M., Heding, A., Schwartz, Thue W. & Elling, C. E., 2007, In: Molecular Pharmacology. 73, 2, p. 349-58 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype

      Jorgensen, R., Martini, L., Schwartz, Thue W. & Elling, C. E., 2005, In: Molecular Endocrinology. 19, 3, p. 812-23 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Characterization of non-peptide antagonist and peptide agonist binding sites of the NK1 receptor with fluorescent ligands

      Turcatti, G., Drozda, S. E., Chassaing, G., Schwartz, Thue W., Chollet, A., Jensen, S. Z. & Lowe III, J. A., 1997, In: Journal of Biological Chemistry. 272, no. 34, p. 21167-21175

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Characterizaton of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype

      Jorgensen, R., Martini, L., Schwartz, Thue W. & Elling, C. E., 2005, In: Molecular Endocrinology. Vol. 19, no.3, p. 812-23

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Common structural basis for constitutive activity of the ghrelin receptor family

      Holst, Birgitte, Holliday, N. D., Bach, Anders, Elling, C. E., Cox, H. M. & Schwartz, Thue W., 2004, In: Journal of Biological Chemistry. 279, 51, p. 53806-17 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Conformational constraining of inactive and active States of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V

      Rosenkilde, Mette, David, R., Oerlecke, I., Benned-Jensen, T., Geumann, U., Beck-Sickinger, A. G. & Schwartz, Thue W., 2006, In: Molecular Pharmacology. 70, 6, p. 1892-901 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Conservation of a helix-stabilizing dipole moment in the PP-fold family of regulatory peptides

      Bjørnholm, B., Jørgensen, Flemming Steen & Schwartz, Thue W., 1993, In: Biochemistry. 32, 12, p. 2954-9 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

      Nygaard, R., Hansen, L. V., Mokrosinski, J., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 25, p. 19625-36 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Constitutive activity of glucagon receptor mutants

      Hjorth, S. A., Ørskov, Cathrine & Schwartz, Thue W., 1998, In: Molecular Endocrinology. 12, no. 1, p. 78-86

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Constitutive and regulated activities of virus-encoded 7TM receptors

      Rosenkilde, Mette & Schwartz, Thue W., 2004, Handbook of Cellular Signalling. Chapter 29 ed. p. 173-76

      Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

    22. Published

      Constitutive ghrelin receptor activity as a signaling set-point in appetite regulation

      Holst, Birgitte & Schwartz, Thue W., 2004, In: TIPS - Trends in Pharmacological Sciences. 25, 3, p. 113-7 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Construction of covalently coupled, concatameric dimers of 7TM receptors

      Terpager, M., Scholl, D. J., Kubale, V., Martini, L., Elling, C. E. & Schwartz, Thue W., 2009, In: Journal of Receptors and Signal Transduction. 29, 5, p. 235-45 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor

      Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 22, p. 12322-7 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Conversion of agonist site to metal-ion chelator site in the ¿2-adrenergic receptor

      Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, no. 22, p. 12322-12327

      Research output: Contribution to journalJournal articleResearchpeer-review

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