Kei Sakamoto
Professor
Sakamoto Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase
Hunter, R. W., Hughey, C. C., Lantier, L., Sundelin, E. I., Peggie, M., Zeqiraj, E., Sicheri, F., Jessen, N., Wasserman, D. H. & Sakamoto, Kei, 1 Sep 2018, In: Nature Medicine. 24, 9, p. 1395-1406 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Metformin selectively targets redox control of complex I energy transduction
Cameron, A. R., Logie, L., Patel, K., Erhardt, S., Bacon, S., Middleton, P., Harthill, J., Forteath, C., Coats, J. T., Kerr, C., Curry, H., Stewart, D., Sakamoto, Kei, Repiščák, P., Paterson, M. J., Hassinen, I., McDougall, G. & Rena, G., Apr 2018, In: Redox Biology. 14, p. 187-197 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
MiR-184 expression is regulated by AMPK in pancreatic islets
Martinez-Sanchez, A., Nguyen-Tu, M. S., Cebola, I., Yavari, A., Marchetti, P., Piemonti, L., De Koning, E., Shapiro, A. M. J., Johnson, P., Sakamoto, Kei, Smith, D. M., Leclerc, I., Ashrafian, H., Ferrer, J. & Rutter, G. A., May 2018, In: FASEB Journal. 32, 5, p. 2587-2600 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking
Chen, S., Wasserman, D. H., MacKintosh, C. & Sakamoto, Kei, 5 Jan 2011, In: Cell Metabolism. 13, 1, p. 68-79 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle
Hunter, R. W., Treebak, Jonas Thue, Wojtaszewski, Jørgen F P & Sakamoto, Kei, 2011, In: Diabetes. 60, 3, p. 766-774 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Molecular mechanism of action of metformin: Old or new insights?
Rena, G., Pearson, E. R. & Sakamoto, Kei, 1 Sep 2013, In: Diabetologia. 56, 9, p. 1898-1906 9 p.Research output: Contribution to journal › Review › Research › peer-review
Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate
Ducommun, S., Deak, M., Sumpton, D., Ford, R. J., Núñez Galindo, A., Kussmann, M., Viollet, B., Steinberg, G. R., Foretz, M., Dayon, L., Morrice, N. A. & Sakamoto, Kei, 1 May 2015, In: Cellular Signalling. 27, 5, p. 978-988 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism
Patra, K. C., Kato, Y., Mizukami, Y., Widholz, S., Boukhali, M., Revenco, I., Grossman, E. A., Ji, F., Sadreyev, R. I., Liss, A. S., Screaton, R. A., Sakamoto, Kei, Ryan, D. P., Mino-Kenudson, M., Castillo, C. F. D., Nomura, D. K., Haas, W. & Bardeesy, N., 1 Jul 2018, In: Nature Cell Biology. 20, 7, p. 811-822 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mutation in the γ2-Subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage
Kim, M., Hunter, R. W., Garcia-Menendez, L., Gong, G., Yang, Y. Y., Kolwicz, S. C., Xu, J., Sakamoto, Kei, Wang, W. & Tian, R., 14 Mar 2014, In: Circulation Research. 114, 6, p. 966-975 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance
Bayascas, J. R., Wullschleger, S., Sakamoto, Kei, García-Martínez, J. M., Clacher, C., Komander, D., Van Aalten, D. M. F., Boini, K. M., Lang, F., Lipina, C., Logie, L., Sutherland, C., Chudek, J. A., Van Diepen, J. A., Voshol, P. J., Lucocq, J. M. & Alessi, D. R., May 2008, In: Molecular and Cellular Biology. 28, 10, p. 3258-3272 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 227976158
Most downloads
-
196
downloads
Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
178
downloads
Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
98
downloads
Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Published