Camilla Charlotte Nielsen Schéele
Associate Professor - Promotion Programme
Schéele Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
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Human Brown Adipocyte Thermogenesis Is Driven by beta 2-AR Stimulation
Blondin, D. P., Nielsen, S., Kuipers, E. N., Severinsen, M. C., Jensen, V. H., Miard, S., Jespersen, N. Z., Kooijman, S., Boon, M. R., Fortin, M., Phoenix, S., Frisch, F., Guerin, B., Turcotte, E. E., Haman, F., Richard, D., Picard, F., Rensen, P. C. N., Schéele, Camilla Charlotte Nielsen & Carpentier, A. C., 2020, In: Cell Metabolism. 32, 2, p. 287-300.e7 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes
Bork-Jensen, J., Schéele, Camilla Charlotte Nielsen, Christophersen, D. V., Nilsson, E., Friedrichsen, M., Fernandez-Twinn, D. S., Grunnet, Louise Groth, Litman, T., Holmstrøm, K., Vind, B., Højlund, K., Beck-Nielsen, H., Wojtaszewski, Jørgen F P, Ozanne, S. E., Pedersen, Bente Klarlund, Poulsen, P. & Vaag, Allan, 2015, In: Diabetologia. 58, 2, p. 363-373 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deficient leukemia inhibitory factor signaling in muscle precursor cells from patients with type 2 diabetes
Broholm, C., Brandt, C., Schultz, N. S., Nielsen, A. R., Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 15 Jul 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 2, p. E283-92Research output: Contribution to journal › Journal article › Research › peer-review
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LIF is a contraction-induced myokine stimulating human myocyte proliferation
Broholm, C., Laye, M. J., Brandt, C., Vadalasetty, R., Pilegaard, Henriette, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2011, In: Journal of Applied Physiology. 111, 1, p. 251-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Epigenetic programming of adipose-derived stem cells in low birthweight individuals
Broholm, C., Olsson, A. H., Perfilyev, A., Hansen, N. S., Schrölkamp, M., Strasko, K. S., Schéele, Camilla Charlotte Nielsen, Ribel-Madsen, R., Mortensen, B., Jørgensen, S. W., Ling, C. & Vaag, Allan, 2016, In: Diabetologia. 59, 12, p. 2664-2673 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Epigenome- and transcriptome-wide changes in muscle stem cells from low birth weight men
Broholm, C., Ribel-Madsen, R., Hjort, L., Olsson, A. H., Ahlers, J. M. D., Hansen, N. S., Schrölkamp, Maren, Gillberg, Linn, Perfilyev, A., Volkov, P., Ling, C., Jørgensen, S. W., Mortensen, B., Hingst, J. R., Wojtaszewski, Jørgen F P, Schéele, Camilla Charlotte Nielsen, Brøns, C., Pedersen, Bente Klarlund & Vaag, Allan, 2020, In: Endocrine Research. 45, 1, p. 58-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The human batokine EPDR1 regulates β-cell metabolism and function
Cataldo Bascunan, Luis Rodrigo, Gao, Q., Argemi Muntadas, Lidia, Hodek, O., Cowan, E., Hladkou, S., Gheibi, S., Spegel, P., Prasad, R. B., Eliasson, L., Schéele, Camilla Charlotte Nielsen, Fex, M., Mulder, H. & Moritz, Thomas, 2022, In: Molecular Metabolism. 66, 14 p., 101629.Research output: Contribution to journal › Journal article › Research › peer-review
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Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes
Davegardh, C., Wedin, E. H., Broholm, C., Henriksen, T. I., Pedersen, M., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen & Ling, C., 2019, In: Stem Cell Research & Therapy. 10Research output: Contribution to journal › Journal article › Research › peer-review
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VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics
Davegårdh, C., Säll, J., Benrick, A., Broholm, C., Volkov, P., Perfilyev, A., Henriksen, T. I., Wu, Y., Hjort, L., Brøns, C., Hansson, O., Pedersen, M., Würthner, J. U., Pfeffer, K., Nilsson, E., Vaag, Allan, Stener-Victorin, E., Pircs, K., Schéele, Camilla Charlotte Nielsen & Ling, C., 2021, In: Nature Communications. 12, 1, 20 p., 2431.Research output: Contribution to journal › Journal article › Research › peer-review
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Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
Davegårdh, C., Broholm, C., Perfilyev, A., Henriksen, T., García-Calzón, S., Peijs, L., Hansen, N. S., Volkov, P., Kjøbsted, Rasmus, Wojtaszewski, Jørgen F P, Pedersen, M., Pedersen, Bente Klarlund, Ballak, D. B., Dinarello, C. A., Heinhuis, B., Joosten, L. A. B., Nilsson, E., Vaag, Allan, Schéele, Camilla Charlotte Nielsen & Ling, C., 2017, In: BMC Medicine. 15, 27 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine
Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, , 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training
Deshmukh, Atul Shahaji, Steenberg, D. E., Hostrup, Morten, Birk, Jesper Bratz, Larsen, Jeppe Kjærgaard, Santos, A., Kjøbsted, Rasmus, Hingst, J. R., Schéele, Camilla Charlotte Nielsen, Murgia, M., Kiens, Bente, Richter, Erik A., Mann, Matthias & Wojtaszewski, Jørgen F P, 2021, In: Nature Communications. 12, 15 p., 304.Research output: Contribution to journal › Journal article › Research › peer-review
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Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity
Gnad, T., Navarro, G., Lahesmaa, M., Reverte-Salisa, L., Copperi, F., Cordomi, A., Naumann, J., Hochhaeuser, A., Haufs-Brusberg, S., Wenzel, D., Suhr, F., Jespersen, N. Z., Scheele, C., Tsvilovskyy, V., Brinkmann, C., Rittweger, J., Dani, C., Kranz, M., Deuther-Conrad, W., Eltzschig, H. K. & 11 others, , 2020, In: Cell Metabolism. 32, 1, p. 56-70.e7 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
Gnad, T., Scheibler, S., von Kügelgen, I., Scheele, C., Kilić, A., Glöde, A., Hoffmann, L. S., Reverte-Salisa, L., Horn, P., Mutlu, S., El-Tayeb, A., Kranz, M., Deuther-Conrad, W., Brust, P., Lidell, M. E., Betz, M. J., Enerbäck, S., Schrader, J., Yegutkin, G. G., Müller, C. E. & 1 others, , 18 Dec 2014, In: Nature. 516, 7531, p. 395-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physical activity is associated with retained muscle metabolism in human myotubes challenged with palmitate
Green, C. J., Bunprajun, T., Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2013, In: The Journal of Physiology. 591, 18, p. 4621-4635 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MultiPep: a hierarchical deep learning approach for multi-label classification of peptide bioactivities
Grønning, Alexander GB, Kacprowski, T. & Schéele, Camilla Charlotte Nielsen, 2021, In: Biology Methods and Protocols. 6, 1, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrating a Multi-label Deep Learning Approach with Protein Information to Compare Bioactive Peptides in Brain and Plasma
Grønning, Alexander GB & Schéele, Camilla Charlotte Nielsen, 2024, Peptidomics: Methods and Protocols. Schrader, M. & Fricker, L. D. (eds.). Humana Press, p. 179-195 17 p. (Methods in Molecular Biology, Vol. 2758).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity
Hayashi, Y., Shimizu, I., Yoshida, Y., Ikegami, R., Suda, M., Katsuumi, G., Fujiki, S., Ozaki, K., Abe, M., Sakimura, K., Okuda, S., Hayano, T., Nakamura, K., Walsh, K., Jespersen, N. Z., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Minamino, T., 2022, In: iScience. 25, 7, 23 p., 104547.Research output: Contribution to journal › Journal article › Research › peer-review
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Brown Adipose Tissue: A Metabolic Regulator in a Hypothalamic Cross Talk?
Henningsen, J. B. & Schéele, Camilla Charlotte Nielsen, 2021, In: Annual Review of Physiology. 83, p. 279-301 23 p.Research output: Contribution to journal › Review › Research › peer-review
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Dysregulated autophagy in muscle precursor cells from humans with type 2 diabetes
Henriksen, T. I., Wigge, L. V., Nielsen, J., Pedersen, Bente Klarlund, Sandri, M. & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes
Henriksen, T. I., Davidsen, P. K., Pedersen, M., Schultz, H. S., Hansen, N. S., Larsen, T. J., Vaag, Allan, Pedersen, Bente Klarlund, Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2017, In: Molecular Metabolism. 6, 7, p. 770-779 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single Cell Analysis Identifies the miRNA Expression Profile of a Subpopulation of Muscle Precursor Cells Unique to Humans With Type 2 Diabetes
Henriksen, T. I., Heywood, S. E., Hansen, N. S., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2018, In: Frontiers in Physiology. 9, p. 1-13 13 p., 883.Research output: Contribution to journal › Journal article › Research › peer-review
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NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program
Hiraike, Y., Waki, H., Yu, J., Nakamura, M., Miyake, K., Nagano, G., Nakaki, R., Suzuki, K., Kobayashi, H., Yamamoto, S., Sun, W., Aoyama, T., Hirota, Y., Ohno, H., Oki, K., Yoneda, M., White, A. P., Tseng, Y-H., Cypess, A. M., Larsen, T. J. & 6 others, , Sep 2017, In: Nature Cell Biology. 19, 9, p. 1081-1092 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PRDM16 stability and metabolically healthy adipose tissue
Horvath, C. & Schéele, Camilla Charlotte Nielsen, 2022, In: Nature Metabolism. 4, p. 1095-1096Research output: Contribution to journal › Comment/debate › Research
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Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity
Ikegami, R., Shimizu, I., Sato, T., Yoshida, Y., Hayashi, Y., Suda, M., Katsuumi, G., Li, J., Wakasugi, T., Minokoshi, Y., Okamoto, S., Hinoi, E., Nielsen, S., Jespersen, N. Z., Schéele, Camilla Charlotte Nielsen, Soga, T. & Minamino, T., 2018, In: Cell Reports. 24, 11, p. 2827-2837.e5 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38541825
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The miRNA Plasma Signature in Response to Acute Aerobic Exercise and Endurance Training
Research output: Contribution to journal › Journal article › Research › peer-review
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327
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
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206
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Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects
Research output: Contribution to journal › Journal article › Research › peer-review
Published