Thue W. Schwartz
Professor
Schwartz Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
- 1986
- Published
Kredsløbsregulation ved hypovolaemisk shock
Sander Jensen, K., Secher, Niels H., Rørsgaard, S., Warberg, J., Astrup, A., Christensen, N. J., Giese, J., Schwartz, Thue W. & Bie, P., 1986, In: Ugeskrift for læger. 148, 38, p. 2383-2387 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1987
- Published
Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
Holst, Jens Juul, Ørskov, Cathrine, Nielsen, Olaf & Schwartz, Thue W., 1987, In: F E B S Letters. 211, 2, p. 169-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-performance liquid chromatography of phenylthiocarbamyl derivatives of amino acids and side-chain derivatized amino acids.
O'Hare, M., Tortora, O., Gether, Ulrik, Nielsen, Henrik & Schwartz, Thue W., Mar 1987, In: Journal of Chromatography.Research output: Contribution to journal › Journal article › Research › peer-review
- 1989
- Published
Release of PYY from pig intestinal mucosa; luminal and neural regulation
Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
- Published
C-terminal KDEL-modified cystatin C is retained in transfected CHO cells
Johansen, T. E., Vogel, Lotte & Schwartz, Thue W., 1990, In: Biochemical and Biophysical Research Communications. 172, 3, p. 1384-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase
Aakerlund, L., Gether, Ulrik, Fuhlendorff, J., Schwartz, Thue W. & Thastrup, Ole, 1990, In: F E B S Letters. 260, 1, p. 73-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
[Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist
Fuhlendorff, J., Gether, Ulrik, Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., Thastrup, Ole & Schwartz, Thue W., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 1, p. 182-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors
Johansen, T. E., Schifter, S., Vogel, Lotte, Tolstoy, S. & Schwartz, Thue W., 1991, In: Molecular and Cellular Endocrinology. 82, 1, p. 51-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Conservation of a helix-stabilizing dipole moment in the PP-fold family of regulatory peptides
Bjørnholm, B., Jørgensen, Flemming Steen & Schwartz, Thue W., 1993, In: Biochemistry. 32, 12, p. 2954-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunohistochemical and chromatographic Identification of Peptides derived from Proneuropeptide Y in the human frontal Cortex
Mikkelsen, J. D., Larsen, P. J., Kruse-Larsen, C., O'Hare, M. M. T. & Schwartz, Thue W., 1993, In: Brain Research Bulletin. 31, p. 415-425Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regional distribution of putative NPY Y*U1 receptors and neurons expressing Y*U1 mRNA in forebrain areas of the rat central nervous system
Larsen, P. J., Sheikh, S. P., Jakobsen, C. R., Schwartz, Thue W. & Mikkelsen, J. D., 1993, In: European Journal of Neuroscience. Vol 5, p. 1622-37Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Molecular mechanism of action of non-peptide ligands for peptide receptors
Schwartz, Thue W., Gether, Ulrik, Schambye, H. T. & Hjorth, Siv Annegrethe, Oct 1995, In: Current Pharmaceutical Design. 1, 3, p. 325-342 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
7TM receptorer - fra lugtesans og nye hormoner til HIV-infektion
Schwartz, Thue W., 1997, In: Ugeskrift for læger. 159, p. 1239-1245Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A broadspectrum chemokine antagonist encoded by Karposis sarcoma associated herpes virus
Kledal, T. N., Rosenkilde, Mette, Coulin, F., Simmons, G., Johnsen, A. H., Alouani, S., Schwartz, Thue W., Poucer, C. A., Lüttichau, H. R., Gerstoft, J., Clapham, P. R., Clark-Lewis, I. & Wells, T. N. C., 1997, In: Kexue (Shanghai). 277, p. 1656-1659Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of non-peptide antagonist and peptide agonist binding sites of the NK1 receptor with fluorescent ligands
Turcatti, G., Drozda, S. E., Chassaing, G., Schwartz, Thue W., Chollet, A., Jensen, S. Z. & Lowe III, J. A., 1997, In: Journal of Biological Chemistry. 272, no. 34, p. 21167-21175Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual agonistic and antagonistic proberty of non-peptide angiotensin AT1 ligands: Susceptibility to receptor mutations
Perlman, S., Costa-Neto, C. M., Miyakawa, A. A., Schambye, H. T., Hjorth, S. A., Paiva, A. C., Rivero, R. A., Greenlee, W. J. & Schwartz, Thue W., 1997, In: Molecular Pharmaceutics. 51, no. 2, p. 301-311Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors
Elling, C. E., Thirstrup, K., Nielsen, S. M., Hjorth, S. A. & Schwartz, Thue W., 1997, In: Structure. 2, no. 4, p. 76-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How receptor mutagenesis may confirm or confuse receptor classification
Schwartz, Thue W., Perlman, S., Rosenkilde, Mette & Hjorth, S. A., 1997, In: Annals of the New York Academy of Sciences. 817, p. 71-84Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metal-ion sites as structural and functional probes of helix-helix interactions in 7TM receptors
Elling, C. E., Thirstrup, K., Nielsen, S. M., Hjorth, S. A. & Schwartz, Thue W., 1997, In: Annals of the New York Academy of Sciences. 814, p. 142-151Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phorbol esters and SDF-1 induce rapid endocytosis and down-modulation of the chemokine receptor CXCR4
Signoret, N., Oldridge, J., Pelchen-Matthews, A., Klasse, P. J., Tran, T., Brass, L. F., Rosenkilde, Mette, Schwartz, Thue W., Luther, M. A., Wells, T. N. C., Hoxie, J. A. & March, M., 1997, In: Journal of Cell Biology. 139, no. 3, p. 651-664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plagiarism of the host immune system - lessons about chemokine immunology from viruses
Wells, T. N. C. & Schwartz, Thue W., 1997, In: Current Opinion in Biotechnology. 8, no. 6, p. 741-748Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist
Simmons, G., Clapham, P. R., Picard, L., Offord, R. E., Rosenkilde, Mette, Schwartz, Thue W., Buser, R., Weels, T. N. C. & Proudfoot, A., 1997, In: Kexue (Shanghai). 276, p. 276-279Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dual nature of the NK-1 receptor
Maggi, C. & Schwartz, Thue W., 1997, In: TIPS - Trends in Pharmacological Sciences. 18, no. 10, p. 351-355Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Den normale hjerne: Ny viden på flere fronter
Pakkenberg, B., Gundersen, H. J. G., Mortensen, Erik Lykke, Lauritzen, Martin, Jeune, B., Regeur, L., West, M. J. & Schwartz, Thue W., 1 Dec 1997, In: Ugeskrift for Laeger. 159, 6, p. 723-727 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Constitutive activity of glucagon receptor mutants
Hjorth, S. A., Ørskov, Cathrine & Schwartz, Thue W., 1998, In: Molecular Endocrinology. 12, no. 1, p. 78-86Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential regulation of CXCR4 and CCR5 endocytosis
Signoret, N., Rosenkilde, Mette, Klasse, P. J., Schwartz, Thue W., Malim, M. H., Hoxie, J. A. & Marsh, M., 1998, In: Journal of Cell Science. 111, no. 18, p. 2819-2830Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational evidence for a common kappa antagonist binding pocket in the wild-type kappa and mutant mu[K303E] opioid receptors
Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 1998, In: Journal of Medicinal Chemistry. 41, p. 4911-4914Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor
Rosenkilde, Mette, Lucibello, M., Holst, Birgitte & Schwartz, Thue W., 1998, In: FEBS Letters. 439, 1-2, p. 35-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles of Agonism - Undressing Efficacy
Schwartz, Thue W. & Ijzermann, A. P., 1998, In: TIPS - Trends in Pharmacological Sciences. 19, no. 11, p. 433-436Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28
Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Split-receptors in the tachykinin NK-1 system - mutational analysis of intracellular loop 3
Nielsen, S. M., Elling, C. E. & Schwartz, Thue W., 1998, In: European Journal of Biochemistry. 251, p. 217-226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor
Holst, Birgitte, Jensen, S. Z., Elling, C. E., Hjorth, S. A. & Schwartz, Thue W., 1998, In: Molecular Pharmacology. 53, no. 1, p. 166-175Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CCR5 receptor acts as an alloantigen in CCR5¿32 homozygous individuals: Identification of chemokine- and HIV-1 blocking human antibodies
Ditzel, H. J., Rosenkilde, Mette, Garred, P., Wang, M., Pedersen, C., Burton, D. R. & Schwartz, Thue W., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, no. 9, p. 5241-5245Research output: Contribution to journal › Journal article › Research › peer-review
- Published
XVI: International Union of Pharmacology Recommendations for the nomenclature of neuropeptide Y, peptide YY and pancreatic polypeptide receptors
Michel, M. C., Beck-Sickinger, A., Cox, H., Doods, H. N., Herzog, H., Larhammer, D., Quirion, R., Schwartz, Thue W. & Westfall, T., 1998, In: Pharmacological Reviews. 50, no. 1, p. 143-150Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
CD4-chemokine receptor hybrids in human immunodeficiency virus type 1 infection
Klasse, P. J., Rosenkilde, Mette, Signoret, N., Pelchen-Matthews, A., Schwartz, Thue W. & Marsh, M., 1999, In: Journal of Virology. 73, no. 9, p. 7453-7466Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor
Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 22, p. 12322-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conversion of agonist site to metal-ion chelator site in the ¿2-adrenergic receptor
Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, no. 22, p. 12322-12327Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74
Rosenkilde, Mette, Kledal, T. N., Bräuner, Hans & Schwartz, Thue W., 8 Jan 1999, In: Journal of Biological Chemistry. 274, 2, p. 956-961Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum
Lüttichau, H. R., J., S., Boesen, T. P., Johnsen, A. H., Chantry, D., Gerstoft, J. & Schwartz, Thue W., 2000, In: Journal of Experimental Medicine. 191, no. 1, p. 171-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of norbinaltorphimine (norBNI) congeners to wild-type and mutant mu and kappa opioid receptors: molecular recognition loci for the pharmacophore and address components of kappa antagonists
Larson, D. L., Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 2000, In: Journal of Medicinal Chemistry. 43, no. 8, p. 1573-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disulfide bridge engineering in the tachykinen NK1 receptor
Elling, C. E., Raffetseder, U., Nielsen, S. M. & Schwartz, Thue W., 2000, In: Biochemistry. 39, no. 4, p. 667-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor
Costa-Neto, C. M., Miyakawa, A. A., Oliveira, L., Hjorth, S. A., Schwartz, Thue W. & Paiva, A. C., 2000, In: British Journal of Pharmacology. 130, no. 6, p. 1263-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor
Holst, Birgitte, Elling, C. E. & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 58, 2, p. 263-70 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor
Rosenkilde, Mette & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 57, no. 3, p. 602-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74
Rosenkilde, Mette, Kledal, T. N., Holst, Peter Johannes & Schwartz, Thue W., 2000, In: Journal of Biological Chemistry. 275, 34, p. 26309-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of chemokine receptors as drug targets
Lüttichau, H. R. & Schwartz, Thue W., 2000, In: Current Opinion in Drug Discovery & Development. 3, no. 5, p. 610-623Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Enhanced fluorescence resonance energy transfer between spectral variants of green fluorescent protein through zinc-site engineering
Jensen, K. K., Martini, L. & Schwartz, Thue W., 2001, In: Biochemistry. 40 (4), p. 938-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MC148 encoded by human molluscum contagiosum poxvirus is an antagonist for human but not murine CCR8
Lüttichau, H. R., Gerstoft, Jan & Schwartz, Thue W., 2001, In: Journal of Leukocyte Biology. 70, 2, p. 277-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine
Mizoue, L. S., Sullivan, S. K., King, D. S., Kledal, T. N., Schwartz, Thue W., Bacon, K. B. & Handel, T. M., 2001, In: Journal of Biological Chemistry. 276, 36, p. 33906-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor
Gerlach, L., Skerlj, R. T., Bridger, G. J. & Schwartz, Thue W., 2001, In: Journal of Biological Chemistry. 276 (17), p. 14153-14160Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11601
Most downloads
-
4519
downloads
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2785
downloads
PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
607
downloads
Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Research output: Contribution to journal › Journal article › Research › peer-review
Published