Thue W. Schwartz

Thue W. Schwartz

Professor

Member of:

    ORCID: 0000-0002-0261-6904

    Publication year:
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    201 - 258 out of 258Page size: 100
    1. 2001
    2. Published

      Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine

      Mizoue, L. S., Sullivan, S. K., King, D. S., Kledal, T. N., Schwartz, Thue W., Bacon, K. B. & Handel, T. M., 2001, In: Journal of Biological Chemistry. 276, 36, p. 33906-14 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor

      Gerlach, L., Skerlj, R. T., Bridger, G. J. & Schwartz, Thue W., 2001, In: Journal of Biological Chemistry. 276 (17), p. 14153-14160

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Mutation of Asp (171) and Asp (262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100

      Hatse, S., Princen, K., Gerlach, L., Bridger, G., Henson, G., De Clercq, E., Schwartz, Thue W. & Schols, D., 2001, In: Molecular Pharmacology. 60 (1), p. 164-173

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100

      Hatse, S., Princen, K., Gerlach, L. O., Bridger, G., Henson, G., De Clercq, E., Schwartz, Thue W. & Schols, D., 2001, In: Molecular Pharmacology. 60, 1, p. 164-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The first PP supper - Camelot at Bispebjerg

      Schwartz, Thue W. & Verlaege, O., 2001, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. vol. 234, p. 109-21

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      The first PP supper--Camelot at Bispebjerg

      Schwartz, Thue W. & Verlaege, O., 2001, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 234, p. 109-21 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus encoded chemokine MC148, inhibits the CCR10 receptor

      Lüttichau, H. R., Lewis, I. C., Gerstoft, J. & Schwartz, Thue W., 2001, In: European Journal of Immunology. 31 (4), p. 1217-1220

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor

      Lüttichau, H. R., Lewis, I. C., Gerstoft, Jan & Schwartz, Thue W., 2001, In: European Journal of Immunology. 31, 4, p. 1217-20 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling

      Fraile-Ramos, A., Kledal, T. N., Pelchen-Matthews, A., Bowers, K., Schwartz, Thue W. & Marsh, M., 2001, In: Molecular Biology of the Cell. 12, 6, p. 1737-49 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity

      Holst, Peter Johannes, Rosenkilde, Mette, Manfra, D., Chen, S. C., Wiekowski, M. T., Holst, Birgitte, Cifire, F., Lipp, M., Schwartz, Thue W. & Lira, S. A., 2001, In: Journal of Clinical Investigation. 108, 12, p. 1789-96 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis

      Holst, Birgitte, Hastrup, H., Raffetseder, U., Martini, L. & Schwartz, Thue W., 2001, In: Journal of Biological Chemistry. 276, 23, p. 19793-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Virally encoded 7TM receptors

      Rosenkilde, Mette, Waldhoer, M., Lüttichau, H. R. & Schwartz, Thue W., 2001, In: Oncogene. 20, 13, p. 1582-93 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. 2000
    15. Published

      A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum

      Lüttichau, H. R., J., S., Boesen, T. P., Johnsen, A. H., Chantry, D., Gerstoft, J. & Schwartz, Thue W., 2000, In: Journal of Experimental Medicine. 191, no. 1, p. 171-80

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Binding of norbinaltorphimine (norBNI) congeners to wild-type and mutant mu and kappa opioid receptors: molecular recognition loci for the pharmacophore and address components of kappa antagonists

      Larson, D. L., Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 2000, In: Journal of Medicinal Chemistry. 43, no. 8, p. 1573-6

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Disulfide bridge engineering in the tachykinen NK1 receptor

      Elling, C. E., Raffetseder, U., Nielsen, S. M. & Schwartz, Thue W., 2000, In: Biochemistry. 39, no. 4, p. 667-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor

      Costa-Neto, C. M., Miyakawa, A. A., Oliveira, L., Hjorth, S. A., Schwartz, Thue W. & Paiva, A. C., 2000, In: British Journal of Pharmacology. 130, no. 6, p. 1263-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor

      Holst, Birgitte, Elling, C. E. & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 58, 2, p. 263-70 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor

      Rosenkilde, Mette & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 57, no. 3, p. 602-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74

      Rosenkilde, Mette, Kledal, T. N., Holst, Peter Johannes & Schwartz, Thue W., 2000, In: Journal of Biological Chemistry. 275, 34, p. 26309-15 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Validation of chemokine receptors as drug targets

      Lüttichau, H. R. & Schwartz, Thue W., 2000, In: Current Opinion in Drug Discovery & Development. 3, no. 5, p. 610-623

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. 1999
    24. Published

      Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

      Rosenkilde, Mette, Kledal, T. N., Bräuner, Hans & Schwartz, Thue W., 8 Jan 1999, In: Journal of Biological Chemistry. 274, 2, p. 956-961

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      CD4-chemokine receptor hybrids in human immunodeficiency virus type 1 infection

      Klasse, P. J., Rosenkilde, Mette, Signoret, N., Pelchen-Matthews, A., Schwartz, Thue W. & Marsh, M., 1999, In: Journal of Virology. 73, no. 9, p. 7453-7466

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Conversion of agonist site to metal-ion chelator site in the beta(2)-adrenergic receptor

      Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 22, p. 12322-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Conversion of agonist site to metal-ion chelator site in the ¿2-adrenergic receptor

      Elling, C. E., Thirstrup, K., Holst, Birgitte & Schwartz, Thue W., 1999, In: Proceedings of the National Academy of Science of the United States of America. 96, no. 22, p. 12322-12327

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. 1998
    29. Published

      Constitutive activity of glucagon receptor mutants

      Hjorth, S. A., Ørskov, Cathrine & Schwartz, Thue W., 1998, In: Molecular Endocrinology. 12, no. 1, p. 78-86

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Differential regulation of CXCR4 and CCR5 endocytosis

      Signoret, N., Rosenkilde, Mette, Klasse, P. J., Schwartz, Thue W., Malim, M. H., Hoxie, J. A. & Marsh, M., 1998, In: Journal of Cell Science. 111, no. 18, p. 2819-2830

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Mutational evidence for a common kappa antagonist binding pocket in the wild-type kappa and mutant mu[K303E] opioid receptors

      Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 1998, In: Journal of Medicinal Chemistry. 41, p. 4911-4914

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor

      Rosenkilde, Mette, Lucibello, M., Holst, Birgitte & Schwartz, Thue W., 1998, In: FEBS Letters. 439, 1-2, p. 35-40 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Principles of Agonism - Undressing Efficacy

      Schwartz, Thue W. & Ijzermann, A. P., 1998, In: TIPS - Trends in Pharmacological Sciences. 19, no. 11, p. 433-436

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28

      Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Split-receptors in the tachykinin NK-1 system - mutational analysis of intracellular loop 3

      Nielsen, S. M., Elling, C. E. & Schwartz, Thue W., 1998, In: European Journal of Biochemistry. 251, p. 217-226

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor

      Holst, Birgitte, Jensen, S. Z., Elling, C. E., Hjorth, S. A. & Schwartz, Thue W., 1998, In: Molecular Pharmacology. 53, no. 1, p. 166-175

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      The CCR5 receptor acts as an alloantigen in CCR5¿32 homozygous individuals: Identification of chemokine- and HIV-1 blocking human antibodies

      Ditzel, H. J., Rosenkilde, Mette, Garred, P., Wang, M., Pedersen, C., Burton, D. R. & Schwartz, Thue W., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, no. 9, p. 5241-5245

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      XVI: International Union of Pharmacology Recommendations for the nomenclature of neuropeptide Y, peptide YY and pancreatic polypeptide receptors

      Michel, M. C., Beck-Sickinger, A., Cox, H., Doods, H. N., Herzog, H., Larhammer, D., Quirion, R., Schwartz, Thue W. & Westfall, T., 1998, In: Pharmacological Reviews. 50, no. 1, p. 143-150

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. 1997
    40. Published

      Den normale hjerne: Ny viden på flere fronter

      Pakkenberg, B., Gundersen, H. J. G., Mortensen, Erik Lykke, Lauritzen, Martin, Jeune, B., Regeur, L., West, M. J. & Schwartz, Thue W., 1 Dec 1997, In: Ugeskrift for Laeger. 159, 6, p. 723-727 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      7TM receptorer - fra lugtesans og nye hormoner til HIV-infektion

      Schwartz, Thue W., 1997, In: Ugeskrift for læger. 159, p. 1239-1245

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      A broadspectrum chemokine antagonist encoded by Karposis sarcoma associated herpes virus

      Kledal, T. N., Rosenkilde, Mette, Coulin, F., Simmons, G., Johnsen, A. H., Alouani, S., Schwartz, Thue W., Poucer, C. A., Lüttichau, H. R., Gerstoft, J., Clapham, P. R., Clark-Lewis, I. & Wells, T. N. C., 1997, In: Kexue (Shanghai). 277, p. 1656-1659

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Characterization of non-peptide antagonist and peptide agonist binding sites of the NK1 receptor with fluorescent ligands

      Turcatti, G., Drozda, S. E., Chassaing, G., Schwartz, Thue W., Chollet, A., Jensen, S. Z. & Lowe III, J. A., 1997, In: Journal of Biological Chemistry. 272, no. 34, p. 21167-21175

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Dual agonistic and antagonistic proberty of non-peptide angiotensin AT1 ligands: Susceptibility to receptor mutations

      Perlman, S., Costa-Neto, C. M., Miyakawa, A. A., Schambye, H. T., Hjorth, S. A., Paiva, A. C., Rivero, R. A., Greenlee, W. J. & Schwartz, Thue W., 1997, In: Molecular Pharmaceutics. 51, no. 2, p. 301-311

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors

      Elling, C. E., Thirstrup, K., Nielsen, S. M., Hjorth, S. A. & Schwartz, Thue W., 1997, In: Structure. 2, no. 4, p. 76-80

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      How receptor mutagenesis may confirm or confuse receptor classification

      Schwartz, Thue W., Perlman, S., Rosenkilde, Mette & Hjorth, S. A., 1997, In: Annals of the New York Academy of Sciences. 817, p. 71-84

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Metal-ion sites as structural and functional probes of helix-helix interactions in 7TM receptors

      Elling, C. E., Thirstrup, K., Nielsen, S. M., Hjorth, S. A. & Schwartz, Thue W., 1997, In: Annals of the New York Academy of Sciences. 814, p. 142-151

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Phorbol esters and SDF-1 induce rapid endocytosis and down-modulation of the chemokine receptor CXCR4

      Signoret, N., Oldridge, J., Pelchen-Matthews, A., Klasse, P. J., Tran, T., Brass, L. F., Rosenkilde, Mette, Schwartz, Thue W., Luther, M. A., Wells, T. N. C., Hoxie, J. A. & March, M., 1997, In: Journal of Cell Biology. 139, no. 3, p. 651-664

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Plagiarism of the host immune system - lessons about chemokine immunology from viruses

      Wells, T. N. C. & Schwartz, Thue W., 1997, In: Current Opinion in Biotechnology. 8, no. 6, p. 741-748

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist

      Simmons, G., Clapham, P. R., Picard, L., Offord, R. E., Rosenkilde, Mette, Schwartz, Thue W., Buser, R., Weels, T. N. C. & Proudfoot, A., 1997, In: Kexue (Shanghai). 276, p. 276-279

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      The dual nature of the NK-1 receptor

      Maggi, C. & Schwartz, Thue W., 1997, In: TIPS - Trends in Pharmacological Sciences. 18, no. 10, p. 351-355

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. 1995
    53. Published

      Molecular mechanism of action of non-peptide ligands for peptide receptors

      Schwartz, Thue W., Gether, Ulrik, Schambye, H. T. & Hjorth, Siv Annegrethe, Oct 1995, In: Current Pharmaceutical Design. 1, 3, p. 325-342 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. 1993
    55. Published

      Conservation of a helix-stabilizing dipole moment in the PP-fold family of regulatory peptides

      Bjørnholm, B., Jørgensen, Flemming Steen & Schwartz, Thue W., 1993, In: Biochemistry. 32, 12, p. 2954-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Immunohistochemical and chromatographic Identification of Peptides derived from Proneuropeptide Y in the human frontal Cortex

      Mikkelsen, J. D., Larsen, P. J., Kruse-Larsen, C., O'Hare, M. M. T. & Schwartz, Thue W., 1993, In: Brain Research Bulletin. 31, p. 415-425

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Regional distribution of putative NPY Y*U1 receptors and neurons expressing Y*U1 mRNA in forebrain areas of the rat central nervous system

      Larsen, P. J., Sheikh, S. P., Jakobsen, C. R., Schwartz, Thue W. & Mikkelsen, J. D., 1993, In: European Journal of Neuroscience. Vol 5, p. 1622-37

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. 1991
    59. Published

      Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors

      Johansen, T. E., Schifter, S., Vogel, Lotte, Tolstoy, S. & Schwartz, Thue W., 1991, In: Molecular and Cellular Endocrinology. 82, 1, p. 51-60 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. 1990
    61. Published

      C-terminal KDEL-modified cystatin C is retained in transfected CHO cells

      Johansen, T. E., Vogel, Lotte & Schwartz, Thue W., 1990, In: Biochemical and Biophysical Research Communications. 172, 3, p. 1384-91 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase

      Aakerlund, L., Gether, Ulrik, Fuhlendorff, J., Schwartz, Thue W. & Thastrup, Ole, 1990, In: F E B S Letters. 260, 1, p. 73-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

      Fuhlendorff, J., Gether, Ulrik, Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., Thastrup, Ole & Schwartz, Thue W., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 1, p. 182-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. 1989
    65. Published

      Release of PYY from pig intestinal mucosa; luminal and neural regulation

      Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. 1987
    67. Published

      High-performance liquid chromatography of phenylthiocarbamyl derivatives of amino acids and side-chain derivatized amino acids.

      O'Hare, M., Tortora, O., Gether, Ulrik, Nielsen, Henrik & Schwartz, Thue W., Mar 1987, In: Journal of Chromatography.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut

      Holst, Jens Juul, Ørskov, Cathrine, Nielsen, Olaf & Schwartz, Thue W., 1987, In: F E B S Letters. 211, 2, p. 169-74 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. 1986
    70. Published

      Kredsløbsregulation ved hypovolaemisk shock

      Sander Jensen, K., Secher, Niels H., Rørsgaard, S., Warberg, J., Astrup, A., Christensen, N. J., Giese, J., Schwartz, Thue W. & Bie, P., 1986, In: Ugeskrift for læger. 148, 38, p. 2383-2387 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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