Thue W. Schwartz
Professor
Schwartz Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
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Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase
Aakerlund, L., Gether, Ulrik, Fuhlendorff, J., Schwartz, Thue W. & Thastrup, Ole, 1990, In: F E B S Letters. 260, 1, p. 73-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle
Abdelmoez, A. M., Dmytriyeva, O., Zurke, Y. X., Trauelsen, Mette, Marica, A. A., Savikj, M., Smith, J. A. B., Monaco, C., Schwartz, Thue W., Krook, A. & Pillon, N. J., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 324, 4, p. E289-E298 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, , 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans
Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, Niels, Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissecting signaling and functions of adhesion G protein-coupled receptors
Araç, D., Aust, G., Calebiro, D., Engel, F. B., Formstone, C., Goffinet, A., Hamann, J., Kittel, R. J., Liebscher, I., Lin, H-H., Monk, K. R., Petrenko, A., Piao, X., Prömel, S., Schiöth, H. B., Schwartz, T. W., Stacey, M., Ushkaryov, Y. A., Wobus, M., Wolfrum, U. & 2 others, , Dec 2012, In: Annals of the New York Academy of Sciences. 1276, p. 1-25 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial regulation of the L cell transcriptome
Arora, Tulika, Akrami, R., Pais, R., Bergqvist, L., Johansson, B. R., Schwartz, Thue W., Reimann, F., Gribble, F. M. & Bäckhed, F., 2018, In: Scientific Reports. 8, p. 1-9 1207.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans
Baumgartner, R., Berg, M., Matic, L., Polyzos, K. P., Forteza, M. J., Hjorth, Siv Annegrethe, Schwartz, Thue W., Paulson-Berne, G., Hansson, G. K., Hedin, U. & Ketelhuth, D. F. J., 2021, In: Journal of Internal Medicine. 289, 1, p. 53-68 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice
Baumgartner, R., Casagrande, F. B., Mikkelsen, R. B., Berg, M., Polyzos, K. A., Forteza, M. J., Arora, A., Schwartz, Thue W., Hjorth, Siv Annegrethe & Ketelhuth, D. F. J., 2021, In: Metabolites. 11, 7, 10 p., 411.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation
Bellmann-Sickert, K., Elling, C. E., Madsen, A. N., Little, P. B., Lundgren, K., Gerlach, L., Bergmann, R., Holst, Birgitte, Schwartz, Thue W. & Beck-Sickinger, A. G., 2011, In: Journal of Medicinal Chemistry. 54, 8, p. 2658-67 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ligand Modulation of the Epstein-Barr Virus-induced Seven-transmembrane Receptor EBI2: IDENTIFICATION OF A POTENT AND EFFICACIOUS INVERSE AGONIST
Benned-Jensen, T., Smethurst, C., Holst, Peter Johannes, Page, K. R., Sauls, H., Sivertsen, B. B., Schwartz, Thue W., Blanchard, A., Jepras, R. & Rosenkilde, Mette, 19 Aug 2011, In: Journal of Biological Chemistry. 286, p. 29292-29302 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conservation of a helix-stabilizing dipole moment in the PP-fold family of regulatory peptides
Bjørnholm, B., Jørgensen, Flemming Steen & Schwartz, Thue W., 1993, In: Biochemistry. 32, 12, p. 2954-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single-chain vascular endothelial growth factor variant with antagonist activity
Boesen, T. P., Soni, B., Schwartz, Thue W. & Halkier, T., 2002, In: Journal of Biological Chemistry. 277, 43, p. 40335-41 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor
Casarosa, P., Waldhoer, M., LiWang, P. J., Vischer, H. F., Kledal, T., Timmerman, H., Schwartz, Thue W., Smit, M. J. & Leurs, R., 2005, In: Journal of Biological Chemistry. 280, 5, p. 3275-3285 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
Chen, S., Lu, M., Liu, D., Yang, L., Yi, C., Ma, L., Zhang, H., Liu, Q., Frimurer, Thomas Michael, Wang, M., Schwartz, Thue W., Stevens, R. C., Wu, B., Wuthrich, K. & Zhao, Q., 2019, In: Nature Communications. 10, 8 p., 638.Research output: Contribution to journal › Journal article › Research › peer-review
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Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112
Cornelia Peeters, M., Mos, I., Lenselink, E. B., Lucchesi, M., IJzerman, A. P. & Schwartz, Thue W., May 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 5, p. 1836-1848 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration
Cornelia Peeters, M., Fokkelman, M., Boogaard, B., Egerod, Kristoffer Lihme, van de Water, B., IJzerman, A. P. & Schwartz, Thue W., Dec 2015, In: Cellular Signalling. 27, 12, p. 2579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor
Costa-Neto, C. M., Miyakawa, A. A., Oliveira, L., Hjorth, S. A., Schwartz, Thue W. & Paiva, A. C., 2000, In: British Journal of Pharmacology. 130, no. 6, p. 1263-8Research output: Contribution to journal › Journal article › Research › peer-review
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Interaction of a non-peptide agonist with angiotensin II AT1 receptor mutants
Costa-Neto, C. M., Miyakawa, A. A., Pesquero, J. B., Oliveira, L., Hjorth, S. A., Schwartz, Thue W. & Paiva, A. C. M., 2002, In: Canadian Journal of Physiology and Pharmacology. 80, 5, p. 413-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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G protein-coupled receptor modulation with pepducins: moving closer to the clinic
Dimond, P., Carlson, K., Bouvier, M., Gerard, C., Xu, L., Covic, L., Agarwal, A., Ernst, O. P., Janz, J. M., Schwartz, Thue W., Gardella, T. J., Milligan, G., Kuliopulos, A., Sakmar, T. P. & Hunt III, S. W., May 2011, In: New York Academy of Sciences. Annals. 1226, p. 34-49 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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G protein-coupled receptor modulation with pepducins: moving closer to the clinic
Dimond, P., Carlson, K., Bouvier, M., Gerard, C., Xu, L., Covic, L., Agarwal, A., Ernst, O. P., Janz, J. M., Schwartz, Thue W., Gardella, T. J., Milligan, G., Kuliopulos, A., Sakmar, T. P. & Hunt, S. W., 2011, In: Annals of the New York Academy of Sciences. 1226, p. 34-49 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The CCR5 receptor acts as an alloantigen in CCR5¿32 homozygous individuals: Identification of chemokine- and HIV-1 blocking human antibodies
Ditzel, H. J., Rosenkilde, Mette, Garred, P., Wang, M., Pedersen, C., Burton, D. R. & Schwartz, Thue W., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, no. 9, p. 5241-5245Research output: Contribution to journal › Journal article › Research › peer-review
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GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue.
Egerod, Kristoffer Lihme, Holst, Birgitte, Petersen, P. S., Hansen, Jacob B., Mulder, J., Hökfelt, T. & Schwartz, Thue W., 2007, In: Molecular Endocrinology. 21, 7, p. 1685-98 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells
Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11601
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
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607
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Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Research output: Contribution to journal › Journal article › Research › peer-review
Published